Harvard Professor Explains How To Reverse The Aging Process Feat. David Sinclair

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#EdMylett #Motivation

[@sandybayes]

I'm 80 and just started Portfolio Diet because of elevated LP(a). in an effort to reduce it. Have been following Sinclair for over a year and I now feel hopeful about living better than I did. Also eat on a time restricted eating plan and have started a better daily exercise plan It makes me happy to do all this.

[@PiereRey]

Z❤😊

[@zzzzxxxx341]

Humans are created to live forever by God the Father. Just as the universe is in existence eternally humans are meant to exist forever in peace and harmony. However since the world is corrupted by sin, people cannot escape the trauma of growing old and eventually dying. Doctors can prolong life in a few years but that is nothing compared to the fear-inspiring power of God which holds the unimaginable vastness of the universe in existence eternally. Seize the day, life is beautiful. Open your eyes to the beauty of nature and the vastness of heaven. Ecclesiastes 11:9 Young people, enjoy your youth. Be happy while you are still young. Do what you want to do, and follow your heart's desire. But remember that God is going to judge you for whatever you do. Amen

[@corinedebekker8895]

So great of you!!❤

[@paulasweeney7713]

Excellent information. to. Enhance your health physically. Mentally, emotionally in strength &. Longevity towards a very happy life . Thank. You for your expertise & excitement Towards a much better attitude towards life blessed . Much appreciated. !!!!🥰🥰🥰🥰🥰🥰🥰

[@denisarobinson-moore1909]

Live long and happily beautiful woman

[@michellelakeart]

I think happiness is much easier if you feel well. If you have no pain.

[@gregbailey45]

Of course!

[@dr.kapilaranasinghe7823]

True its in and with in i guess

[@morganjones5890]

I really love how humble and down to earth he is about all of this.

[@morganjones5890]

Well now the video switched in the middle to a different interview! What happened?

[@denisarobinson-moore1909]

I am a woman and I have been recently sad, confused and discouraged because of all the different information on the same subject. Basically rabbit hole. You guy's just gave me a sense of peace and assurance to stick to what I followed in a first place. Thank you is not sufficiently enough to express my appreciation of you both. Ed it would be tremendous to do a video specifically designed for women as I feel there are certain differences we should be doing according to our cycle as an example. Regardless please stay alive as long as possible because we need you. Sending smile and hugs to both of you.

[@eclub1012]

These branches of science are difficult to apply for a variety of reasons. I suggest you stick to ancient healthy diets such as the Mediterranean or Indian, going for their plant-based varieties. They have been studied by these scientists and they only tweaked a few things here and there, minor elements. You can't go wrong.

[@denisarobinson-moore1909]

@eclub1012 thank you. That's actually what I do . Best way

[@artysan21]

Ed, This is my first ever by chance to come across your video interview with David Sinclair. Both of you are great people. I'm fascinated and always interested in this longevity subject by observations, analysis, practices what I know of by eating and drinking good healthy food, doing physical and mental/spiritual exercises. I'm 73/74 but feel 20 or more younger. I run regularly. I don't take any tablets. What David says 95% I agree with. He is absolutely right. The other 5% has not mentioned yet is how our mind shape our lives, our health. David is a rare human being who thinks for common good to others. Ed, you are great. God bless you both. Love and peace. Topo xx

[@caroldoddart]

This is a great interview (but because he’s like me… I’ve watched or read volumes on longevity,) but there are still questions we have because we’re not scientist --and Ed is asking them! It’s just a marvelous interview. And this is easily the 10th one of Dr. Sinclair’s I’ve watched.

[@olamarina7792]

Great interview Ed! You do ask the right questions and get the most out of David S. I’m 62 and will never give up on health, beauty and longevity.

[@carlakenyon6073]

Sadly, I get compliments regarding how young I look and in shape, I follow Dr. Sinclair…..health should be the goal. Most of the people I know, as they age, look like 💩

[@Kazjal]

David Sinclair deserves Nobel prize for the excellent work he does 🎉❤ Well done for a great interview/chat both ❤❤

[@carlakenyon6073]

Agreed but spell his name correctly

[@Kazjal]

@@carlakenyon6073 THANKS 🌹

[@LuciousKage]

for talking ? years passed and there is not any prove or paper he put for peer review that proves any progress in reverse or stop aging. but hey, he sells more books

[@miker7808]

Check out the latest news concerning him, you will find a whole new way to describe him.

[@Lopata991]

He is a grifter, don't buy his products or believe his lies. Just stick to a healthy diet. This joker aint it

[@krisdire923]

This is the best Sinclair interview ever done. Great questions. Well done mate and thank you!

[@jillianmartin6335]

Thank you. This is amazing. I naturally have never had breakfast. Rarely lunch, and eat my meal at night. I am 54, and my patients I work with in the community do not believe my age. They think I am late 30s early 40s. I do have fibromyalgia, which is challenging and affects my exercise, but I do live as healthily as possible. Can you possibly do an interview on fibromyalgia and cfs? That would be amazing. Thank you.

[@kathyhou4648]

Thank you so much for such amazing content!!!! So much valuable information that can help us right now!!!!

[@SilverFan21k]

Awesome video Ed! Thanks for having David on and covering Aging.

[@MicahBratt]

Great work David! Your work makes the future look brighter

[@stephaniehendricks225]

Sinclair seems to really open up to Ed and give new info! Great stuff

[@Diamond_Motivation]

I love this!! It spoke to my spirit!! Let's get it done!!!

[@michellefilak6783]

Outstanding podcast! Thanks for asking Dr Sinclair great questions!

[@SilverFan21k]

I appreciate you often covering longevity and life extension topics. This came up on my recommended.

[@qhride1]

Wow this was the best ever pod cast discussion to date this guy is of the scale incredible! I will keep an eye on this professor 👍

[@olgasel6186]

Sinclair is so inspirational. Thanks for this video

[@allanpaterson6146]

Great interview thank you so much

[@roniesousa1587]

I admire David Sinclair a lot . Amazing interview

[@jpjames8044]

Dr. Sinclair you are an AVATAR from the light. THANK YOU FOR YOUR WORK

[@davincimen4495]

This is the most mine blowing health and wellness podcast that perhaps has ever been recorded, certainly that I’ve heard, in terms of what is disclosed and how revolutionary all of this research is, and it’s sci-fi implications if it could be realized.

[@grantburris]

Wonderful talk. I always learn something. Sometimes I learn a lot. Thanks to both of you for generating such highly useful dialogue. I attempt to follow every word David Sinclair says. This was an especially good one.

[@ligiasommers]

Thank you for that !!! 🙏🏻🎉🎁✨🙏🏻

[@ACE_dll]

Phenomenal interview!

[@JonClaudeondaBeat]

Thank you so much Ed Mylett for this timeless video! Creating history on the channel 🙌

[@AprilDevelossings]

Thank you Dr. David!!!!! 😊 This is absolutely your calling..😊

[@huha47]

In a couple of months I will be 77, looking at least 20 years younger. Longevity for me has to do naturally with my DNA, as several family members lived to their late 90s, including my great uncle who was 99. I've been a vegetarian for almost 40 years, have played a lot of tennis and golf, did a lot of skiing when I was younger living 15 minutes from the ski area. I'm a rather extreme walker, averaging 500km / month. In 2022 effectively the distance from San Francisco to NYC. Mentally, very acute, do a lot of sudocus daily, read a lot, amongst other things. I don't consider myself to be old, and quite frankly, I can't relate to people my age. Staying healthy is a priority.

[@Danybella]

Good for you!!

[@tasst2674]

I love dr. Sinclair. Lots of longevity on my Dad’s side with them living to 102, 97 and my dad 95.5, but they all suffered at the end which I am trying to minimize. Thank you both!

[@sinagtalamalaya5392]

David Sinclair inspires me ❤

[@valleyislekombucha.amazing5504]

Great episode!!🤙🏼

[@tijuana_503]

This info gives me hope that in the future I will feel and look young when when my kids get older 😃

[@user-uq5go5ey6b]

Dr. Sinclair is the real deal 🤝 Thanks for this recording 👏

[@virginiaholzer7358]

These are mind blowing for me ,wow❤

[@waynesanders1406]

I've listened to a lot of podcasts and remember Charles Poliquinn saying on an episode with either Tim or Mike Mahler that searching published articles on usage of fish oil (which he said improves cellular signaling, because a cell's exterior wall is a lipid layer) showing that increasing fish oil dosages reduced all forms of diseases ranged in the thousands. Fish oil consumption improves cellular signaling (cells don't forget what they are), and as a result diseases / aging processes are diminished. Also, regarding metformin, the natural herbal remedy that preceded (and was the model for formulating the pharmaceutical) is berberine. That one came out on the podcast with Tim. I'm always a fan of natural earth remedies over things made in labs myself, and it's available to everyone. As with any supplement, make sure it's a good brand not made in China (Thorne is my personal go-to brand for anything).

[@jellybeanvinkler4878]

Search Sally Norton. Or check out her book, Toxic super foods. You can stay vegetarian or vegan, which I don't recommend, but get rid of high oxalate foods. Your aches and pains will magically disappear.

[@gwendawnseto2284]

Thank you Wayne

[@linqt9504]

Great interview Ed and thank you Dr. David for your hard work! Do you recommend for everyone to take these meds?

[@Littleboy1976]

WOW! That was a damn good show! ♥️💪

[@adrianaradu9971]

Great talk and legendary work and book. I wonder Dr Sinclair‘opinion on taking the Metformin immediate-release or rather the extended-release form?

[@8JaneSmith8]

One of the greatest podcasts ever! Thank you so much! Long and productive lives guys! God bless!

[@himakakani6274]

Yes, thank God, that Dr. Sinclair exists!

[@mdub1230]

thanks ED and Dave awesome info I need my credit score😊

[@delliscool4924]

please do your best Dr, we all are eager to see something sold about reversing aging.

[@mrapp9457]

really like this guy. I'm reading his book Lifespan.

[@xhango0kx]

love your videos. can you let your editor know that the volume is extremely low? Gotta always turn the volume up alll the way up

[@codefordev911]

The part of this video which really resonate me when you ask david about, what a person can do if he/she dont have such medical facilities , and they replied, control your diet, daily excercise at least 40 minutes and manage your stress, be happy , will really extend your life without taking any pilll for this❤

[@frankteddy8823]

Ed i never fast forward one second of your videos. Thanks brother. You got a huge fan from Toronto

[@christianleadershippartners]

This is such good information, thank you so much for putting out this important information!

[@MrLoreto99]

Thank you Valuable 💯🇸🇧

[@TroyBrooksPainter]

This was a great talk. I do wish he would rethink his position on producing his own supplement system. There are so many untrustworthy companies sponging off his name that I think it would set the standard and eliminate all the poorly implemented knock offs.

[@abdulazuzadel4768]

why do you think he is trustworthy? I struggle to believe his info.

[@lisabeck5582]

This video short makes me wonder where you live because some of the comments from those in warm climates make sense. As for me, all of your suggestions make perfect sense and I plan to follow your suggestions to see what happens. I’m a little nervous to waste a good bell pepper by leaving it out of the fridge but my curiosity makes me want to take a chance and see what happens.

[@jimwilliams3333]

I love this interview between Ed Mylett and Dr. David Sinclair. Very interesting. I'm maybe genetically predisposed to live longer. I don't drink or smoke helps but both sides of my family live long even with drinking and smoking unfiltered Lucky Strikes. The picture of me is about 80, 170 lbs. 6 ft. I'm now started taking these recommendations of Dr. David Sinclair.

[@DanteLikesRock]

you're 80 in your pic?🤣

[@mrapp9457]

Ed , this is the first time I am listening to your program. its great

[@an9546]

What an amazing man. Thanks for bringing him

[@teacherjosephkuan]

🎯 Key Takeaways for quick navigation: 00:26 🕰️ *The Horvath clock is a new way of measuring biological aging, providing accurate predictions of lifespan.* 03:00 🩺 *Metformin can help reduce inflammation, prevent type 2 diabetes, and potentially extend lifespan.* 05:03 💊 *Metformin may slightly affect muscle hypertrophy, but it still promotes strength and overall health.* 12:30 🍷 *Resveratrol can activate anti-aging pathways, but its effectiveness depends on proper absorption and lifestyle choices.* 18:50 🐭 *Researchers are exploring genetic modifications in mice to better understand the impact of substances like Resveratrol on aging.* 19:04 🧬 *Aging-related diseases can potentially be addressed by NAD boosters, exercise, and intermittent fasting to maintain NAD levels.* 21:24 🍇 *Resveratrol should be taken with something like yogurt or milk to enhance absorption and effectiveness.* 25:09 💪 *Combining metformin, resveratrol, and NAD boosters may help rejuvenate the body and activate longevity genes.* 29:21 🧬 *Aging is influenced by epigenetic changes, where cells lose their ability to read DNA correctly over time.* 32:59 👁️ *Research is underway to reverse aging in the eyes, potentially leading to vision restoration and broader applications for longevity.* 38:35 🧬 *Centenarians (people over 100) tend to die quickly from heart attacks or kidney failure and cost less in healthcare, which highlights the importance of staying healthy for longer.* 39:16 📚 *Following Harvard Professor David Sinclair and his work on aging can help individuals live better, longer, and healthier lives.* 40:12 🧬 *The future of anti-aging may involve gene editing technologies like CRISPR, promising potential to extend human lifespans.* 43:23 🧬 *Genetic modifications to resist diseases and enhance longevity are on the horizon, raising ethical questions about the implications of such interventions.* 45:13 🍽️ *Simple steps to potentially reverse the aging process include intermittent fasting (eating less often), regular exercise, and finding happiness, as happy people tend to live longer.* 58:04 🩺 *Testosterone may help with muscle strength and prevent falls but doesn't appear to extend lifespan.* 59:56 🦠 *Low levels of growth hormone might lead to a longer life, as excess growth hormone could have adverse effects, although it may make you feel and heal better.* 01:02:42 🧬 *NAD (nicotinamide mononucleotide) supplementation can potentially activate enzymes that protect the body and slow down the aging process.* 01:09:21 💉 *Metformin can help protect against age-related diseases, especially for individuals predisposed to conditions like cardiovascular disease and diabetes.* 01:15:46 🧬 *Research suggests the ability to reset the age of complex tissues, like the eye, in mice, offering the potential to rejuvenate tissues in humans and potentially cure blindness. Human trials are in progress.* 01:17:23 🔄 *Harvard Professor David Sinclair discusses a universal reset switch in the body that can reset different parts, including the skin and muscles, making them younger.* 01:18:04 🤯 *David Sinclair mentions the potential to reset the age of the human body, a breakthrough already achieved in mice, highlighting the exciting possibilities of reversing aging.* 01:18:57 💊 *A study by UCLA's Steve Horvath and Greg Fay shows that a combination of metformin, growth hormone, and DHEA can reverse the biological clock by about 2 years in humans, suggesting the potential for reversing aging.* 01:19:55 👨‍🔬 *David Sinclair discusses his ability to createpluripotent stem cells from human skin cells and even grow mini organs, emphasizing the potential for personalized medicine and organ testing.* 01:26:13 💡 *David Sinclair touches on his work in preserving fruit shelf life, highlighting how advances in health and longevity can benefit the economy and help address global issues like food supply and climate change.* Made with HARPA AI

[@bobsmith5441]

You're a legend. Thank you so much

[@bsonder]

Thank you.

[@heidir8695]

Exceptional Video. Wow, Am a follower of Dr. Sinclair What an Awesome Amazing Man love this video with these two , so informative, What a Blessing to have two wonderful amazing individuals here. God Bless you both love you. Excellent Video❤

[@gustavopanesso7297]

Great podcast ❤

[@sacredneutral7304]

You reduce aging by living in the moment and doing what you love as much as you can... You create less time and age much less when you are in a constant state of joy

[@lizlambert]

And of course God decides ❤

[@sacredneutral7304]

@lizlambert Hmmm not really but I see what you mean

[@jillwinitana4254]

I'm going to follow this man This sounds sense...Amazing.. Already lm younger looking by 20 yrs....n lm 70 next week...from diet veges good eating...my bloods are great..l got myself off insulin this way n l need to maintain... Thanks♥️

[@drdanielmiezah]

Great topic

[@henrygreen7956]

Dr S, I am hopeful you are going to tell us soon about how cartilage can be stimulated to regrow. This is exciting.

[@geetajain5433]

Dear Mr Ed Mylett, Watched your podcast for first time. I believe you must have struggled alot to develop viewes, success principles which are mentioned in Bhawat Gita( like Bible for Hindu's written 5000 years ago) I am writing my comment for David Sinclair . His work deserves Noble Prize, you should visit his lab. David Sinclair is a very humble man. person got impression Watching podcast. You can bring him to limelight. God bless you. Dr Jain

[@imranahmed-yp9in]

I am Neuro Psychiatrist from Pakistan 🇵🇰 Thought provoking, No doubt, Thanks. Dr Sinclair.

[@mgmossi5861]

Mr Sinclare is fantastic been following him for about one year.

[@benlassu1880]

I am lucky to have the FOXO3 gene and long Telomeres. At 60+ I'm looking forward to Sinclair's studies and recommendations.

[@cindyd1042]

Loved this podcast!!! 💕 I follow both of you great men!!

[@shahnazparveen6648]

I myself was also working from 1993 I am glad he has already come up with exact that solutions😊🌺🥀🌹💐🌻❤ I live in India where we get negative support from the entire country no one appreciates so I was just reading and searching online There was nothing more I could do.

[@virginiaholzer7358]

Am i hearing miracle, amazing thanks, i appreciate 🙏 💗 this information

[@annavieste7208]

I love Dr David’s courage . What a wonderful scientist . Just amazing . Thank you for this interview ♥️ Living extended lives we really need to think about food . Eating animals should not happen ( for soooo many reasons ) hopefully we will evolve into kinder humans and not turn into some future filled with greed and disregard for the planet and it’s inhabitants. Nice to hear about growing body parts and brains and hopefully animal testing will end soon .

[@1160lance]

Ed long term listened: Resveratrol power with yogurt: is the best way to take? So many choices in which place is the best to buy. Lance

[@infodiff]

excellent interview and answers, i think both u and david enjoyed this session, both were in smiles and bubbling out with energy.

[@xAzurasKnightx]

I did this for some time and was really performing best ever with it.... then came the global illness and all I did was declared wrong and it was impossible to exercise (in my habitat), and so I let it all go. Result: inflammations head to toe, obesity, superfast shrinking in length, aso.... And now I watch you guys, and yes..... going to get that car rolling again.

[@CUMBICA1970]

Hope we see some breakthrough soon. But it's too late for my folks both pushing 90. It's just heartbreaking to see they don't recognize anyone anymore because of dementia. Surely Mr. Sinclair knows the pain as he lost his mother at a relatively young age and it's remarkable how he translated his grief into a lifelong quest to cure ageing (or at least to slow down.)

[@STEELESTRENGTHANDCONDITI-jq5km]

"Create a life you want to live longer for" is the best line in this interview imo. @Edmylett you should do a whole episode on this.

[@LETSGODYDYNA]

David Sinclair is great, but he doesn’t work out intensely or regularly with a primary goal of increase aerobic and anaerobic performance. Metformin downregulates mitochondrial capacity so you may live longer, but with lower oxidative and glycolysis capability

[@grantburris]

Well Done by each of you. I watch everything new that David does. He looks younger each time I see him. No doubt David is self medicating.

[@GlacialRidgeHomestead]

Loved this interview. New sub here.

[@nancyvickers2814]

We can’t all learn like you - most of us don’t have enough science education! I actually think I have a small advantage because I have worked in the medical field (EMT) so I At least familiar with a few processes and structures like amino acids etc - so thanks for the guide book!

[@AFSMG]

In what foods do we find NAD?thank you so much

[@JGLOVER0118]

Doc, I need you start with this skin..

[@Randy22124]

Thanks!

[@Virgiemendo]

I would definitely be your Quineapig. I am 54 years old and would be involved in that. Awesome!!

[@fhsa7239]

Can you be mine? Dominant guy here, I'd love to have someone for quite a lot of things

[@dequentinmiller9086]

This interview is going to blow up once the first age reversal pill actually releases. Or maybe even before then when peoples sight is restored or if we even grow new eyeballs onto people.

[@damienlittle9913]

“Create a life that we want to live longer for”

[@lianam3262]

LOL ..yeah. right !:))) ""They "" ""there"" are so much interested to make your life " so precious for them :) " better and better..for Your M-ty would appreciate it more - to live ..." much longer " .Wake up :))))

[@mitchdg5303]

what did you just type?@@lianam3262

[@jtonne3057]

I wonder what Mr. Sinclair’s take is on plant and autoimmune issues. There are people who’ve purportedly switched to a ketovore or carnivore and their issues disappeared. Always look forward to his research, fascinating!

[@oanairani41]

In his previous videos he switched to a vegan diet, i believe one meal a day. I dont know if he did any changes to his diet.

[@cayanne3622]

Love David , so caring and passionate ❤

[@gracielazozaya2103]

Where do I sign up? Is there a way to sign up as a research subject with Dr. Sinclair?

[@Littleboy1976]

This should have 100 Million Views! I have to watch it twice!!! My Wife actually buys me Resveratrol! Now I'm going to go M,W,F not everyday. 💪♥️

[@sandravillegas2829]

Thank YOU! One question, what are the side effects of Resveratrol?

[@shahzamanhaque]

David Sinclair has somewhat edge on Peter Attia but he might be not as eloquent as Attia and Rhonda. I never misses any new interview of Sinclair.

[@dalevandenheuvel3927]

Just a question in regards to the yogurt Dr. Sinclair mix does it happen to be coconut yogurt made from young coconuts and probiotics?

[@jacquelinejimenez8537]

Ed your super handsome!!!!!!!!! Just thought you needed to know 🤷‍♀️

[@yesicasuarez8313]

Hi, firstly thank you for this information. But i did watch the whole interview but i did not see clarification on what you and Dr. Sinclair mean by doing "hot and cold"?

[@jimmykohpbm1543]

Very Good 👍👍👍👍👍👍

[@dynamicalan]

What do you think about Life +. Salt and corn starch does it get in the say? I need to use Chipotle Salsa.

[@donnajulliet]

wow Ed, that hit me, "Create a life you want to live longer for."

[@angelamarcelapappas7035]

What an amazing show. Thank you for bringing such cutting edge information to us. As a mom, I always wonder how to help or maximize our children. Like I feel like my 4 year old son needs to eat 3 meals and he doesn’t think or feels the same. Maybe I just need to relax

[@NinjaCoderInTraining]

How much do different cell populations vary in terms of epigenetic age though? I'm not super convinced that a blood test is an adequate measure of overall aging.

[@TS-uz4zb]

Does health insurance will support this revolution on aging and pay for testing/ specific blood work/ genetic testing ?

[@rebeccawhiteofficialanoint4282]

I would be for, and that includes approving, procedures that turn off bad disease-causing genes, if and only if a person's own genetic material were used to do it and not someone or some animals genetic material. The reason why this differentiation is so critical and will be key to getting such procedures approved, is because there are currently a lot of people out there with non-human DNA in them, and not altering a human to a partial or fully non-human DNA status would be a prerequisite of any kind of approval for drugs or therapies. First and foremost, we need to protect the Adamic race who are purebred children of Adam and Eve. We know the ones with non-human DNA have already been monkeying with their own DNA for eons, therefore it is the Adamic race that must be protected.