Hirschsprung's Disease

This video contains an explanation of Hirschsprung's disease, aimed at helping medical students and healthcare professionals prepare for exams.
More written notes and diagrams about Hirschsprung's disease are available on the website at www.zerotofinals.com/hirschsprungs.
Zero to Finals Medicine book:
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US: www.amazon.com/dp/1091859892
Zero to Finals Paediatrics book:
UK: www.amazon.co.uk/dp/1080142827
US: www.amazon.com/dp/1080142827
Zero to Finals Obstetrics and Gynaecology book:
UK: www.amazon.co.uk/dp/B08K4K2WQB
US: www.amazon.com/dp/B08K4K2WQB
Website: www.zerotofinals.com
Notes: www.zerotofinals.com/learn
Multiple Choice Questions: www.zerotofinals.com/test
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DISCLAIMER: This video is for education and entertainment only, and is not medical advice. This video should NOT be used for medical advice or to guide clinical practice. The Zero to Finals content should not be used in any way to guide medical decision making. Zero to Finals takes no responsibility for any actions taken or not taken based on the information provided. Local and national guidelines and senior clinicians are there to help you make decisions, not KZbin videos. If you need medical advice or information, seek it from an appropriately trained and licenced doctor or healthcare provider that can address your individual needs. Zero to Finals cannot guarantee the accuracy of information in this video. Please highlight any errors you notice in the comments below - thank you.

[@enricos.4993]

Born with this disease, got surgery at 3 days old and then again at 1 years old. 20 years later I can say I’m absolutely ok, just two scars on my abdomen!

[@sumblasami6073]

Again surgery means ?????

[@sumblasami6073]

@@enricos.4993 ????????

[@cemilr9648]

İki ameliyyatdan sonra duzeldinizmi please ansver me

[@srisai9553]

Dr are saying they are complications for entercolitis after surgery.this complications is for all patient?or some patient.pls tell me my family members suffer from the disease 🙏and u didn't get any ifection?

[@enricos.4993]

@@srisai9553 didn't get any infection. I don't know whether it's more common to have one or not. As I said before, it's challenging but you can do it!

[@OldSoulInIndiana]

Very nice video. Our youngest was born with Hirschsprung’s and had his pull-through procedure at three months old. He’s done great ever since! Before he was diagnosed my husband and I had never heard of this condition, as it didn’t run in our families.

[@chrisalexio5616]

I was born with this condition.. I was born in ‘97 and I can honestly say this effected my life and my family’s life very much

[@shraddhadhumale2745]

How ru now? Pls reply

[@chrisalexio5616]

@@shraddhadhumale2745 good, very good 😂🙏🏽

[@wyattmcknight4858]

I was also born with this (2005) but the doctors didn’t know till I was about 2 1/2 years old and I’m now fifteen what should I expect in later years?

[@elenageorgoula8575]

I was born with this condition too in 1997. In Greece only some doctors know how to handle this case. I was born in a small town and the doctors said it was just a constipation although I was wearing diapers until 6 1/2 y.o until I went to surgery. God bless my doctor in Athens Mr Geroulanos. I understand exactly how you felt and feel for this condition and also your family.

[@chrisalexio5616]

@@wyattmcknight4858 all I can honestly say is you gotta train your body... I spent the first 13 years of my life going back and forth from the hospitals.. I had about 15 surgeries by that time. By once I entered middle school I knew something had to change. I started playing sports, dating girls, just growing up. Comes a point in life where we know when we gotta go

[@bukanahholly9629]

Wow just found your channel on my suggestions, I must say that your explanations are easy to follow and not complicated. Your site is quite helpful. Thank you and God bless you more.

[@ZeroToFinals]

Thanks. So glad you like the explanations.

[@Iamhermajesty9]

I don’t have this but I’ve been reading about it and will pray for everyone who is affected. I read that it occurs at a rate of about 1 in 5000 and that it is about four times more common in males than females.

[@adesolataiwo7307]

I am grateful to you for this video. Making a presentation on Hirschprings Disease in my Pediatric surgery posting. Thank you!

[@dylanharper354]

I was diagnosed with this as a newborn and got a surgery which removed all the useless intestines, I’m 19 now and the only side effect I see is I have to use the restroom quite often and it is EXTREMELY hard for me to gain weight. Other than that I’m happy I got my surgery

[@BrummieJamie]

Keep going, my friend has suffered with this and he has put loads of weight on now

[@dereksmead4681]

thank you ! these videos rock!

[@joanaprincessmulungi2511]

You have really explained it very very well,

[@Alex73736]

My niece is 11 months old. Two weeks ago she was diagnosed with this disease. The doctor was supposed to perform the surgery very soon, but the baby had developed a pneumonia. My poor niece. This made me really sad 😢 Please pray for my little niece. 😢

[@bonivieortiz4944]

Praying for her and don't worry she will be okay soon

[@sham-3mbzd858]

in love with your videos they made my life easer thanks

[@ZeroToFinals]

So glad to help!

[@amaranextdoor]

Thank you so much! This was very helpful

[@deniseview4253]

Yes, was very helpful. Thank you for the information.

[@Dr_feelgood_zw]

Thank you 🙏 ❤

[@adyanmajid5576]

Nice lecture . Thank you so much

[@adibamayeesha3577]

so much helpful...very nicely described.. Thank you🤍

[@mkangel1937]

I’ve had this condition and went to many doctors about it but everyone of them diagnosed me wrong and I only found out I had this when I was 12

[@happiness965]

I understood the concept , Thank you! but can you explain modified duhamel procedure.

[@roaa_harahshih]

great explanation for this interesting topic

[@katiesann_04]

I was just diagnosed with this disease two days ago and I am 19 years old. I’ve had terrible stomach pain and bloating for my entire life and I’m grateful to finally be educated on my condition. Thank you for the great video. 🤍

[@MrJake11297]

Another excellent video. Please keep making more haha! Thanks

[@ZeroToFinals]

Thanks, will do!

[@mooltz]

25 yr old with Hirschprungs here, I had one pull thru at 7 months old that did NOT get all the anganglionic colon, wasn't until 7 Years old that I had a second pull thru preformed, which got the remaining diseased colon, but was an extremely complication filled recovery process. So much so that I just laugh when any doctor asks me for medical history. Jealous of the kids with only one or two scars, and no trauma. Definitely will not have children unless HD cannot be passed on. I went though hell.

[@Belle2755]

Thank you

[@mareettag.antony1093]

Beautiful lecture ..thank you✨

[@semubanda1788]

This is well explained

[@rugabirasilas]

great job guys

[@chathuridilani5529]

Very helpful love from 🇱🇰

[@user-te6qc9kw6v]

thank u soo much

[@sainidhi5617]

Can someone please clear my doubt. Parasympathetic nerves usually cause contraction of smooth muscles of GIT right... then when there is absence of parasympathetic ganglions, then the smooth muscle must relax... then why is the uninnervated distal part of colon constricted in hirschsprung's disease?

[@greatguyme]

My son got this disease and had to do immediate operation after bowel perforation after 5 days of birth. Now, he have got stoma bag and the doctor's will perform second operation between 6 to 9 months. He's 3 weeks old now and believe me this is very challenging situation for me because I've never heard of this disease and I cried a lot after happening this to him. My wife and I were both managing and try to overcome our pain.

[@shashi8436]

Same problem brother my daughter .... 7month old knw

[@greatguyme]

@@shashi8436 How is she now? I pray for your daughter and your family.

[@sabieh154]

❤❤❤❤

[@ranjann23]

Today Doctor said to me that your 9 days old Son may have hursprumg disease

[@maryannnwokocha1156]

Thank you sir

[@Adnankhan-xr5yc]

very nice explained

[@hannys2990]

I have had symptoms of this disease since I was little. The doctor thinks of shots and examinations that I have this disease. In less than a month, I will go for another examination to confirm his claim. I would never expect to be affected by an illness.

[@ojihasyourback8885]

Thanks

[@bereketgellaw8847]

A great lecturer! 👍👍👍 how could I get all the topics you have please! 🙏

[@alexislozada8726]

I was diagnosed with this at the age of about 14…i was born in 89 doctors always said as a kid i was just scared to use the bathroom had a huge intestine by then a great specialist doctor we found told me what i had after so i had to have a colostomy bag for 3 months to let the intestine swelling go down then do the surgery with another 3 months to let intestine heal then i thought i was done…but wait 4 week after that intestine tided in knot so had to go back..since then I’ve been living normal..before diagnosis i was 89LB soak and wet after all surgery 190 within a year now 35 years old at 205 but i just enjoy eating after all those hospital stay with no food.

[@ronkemperful]

I too was born with this condition. I was misdiagnosed with colic and my mother’s concerns were downplayed by the doctor. It was not until I was five that I had developed a total bowel obstruction that led to peritonitis and a three month hospitalization where I lost 1/2 my body weight, nearly dying. Then for 20 years I still had chronic constipation and poor weight gain for the surgery only resected the ruptured portion of the transverse bowel, probably leaving what caused the blockage intact. However, I somehow managed to recover by the use of fiber and stool softeners… and an infrequent use of an enema. Your great video, I hope, will help someone else from going through what I had gone through as a five year old, sixty-one years ago!

[@Mjjfanforever988]

@ronkemperful is the symptoms gone and can you go every day without pain

[@ronkemperful]

@@Mjjfanforever988 Because much of my transverse colon was removed, the main symptoms during my childhood was chronic constipation alternating with rare bouts of diarrhea, but strangely that mostly disappeared after I started work as a nurse for 40 years (maybe I picked up a bug!). Now as I have retired the constipation has come back but is manageable with a daily dose of fiber, fluids and with a balanced diet. Once in a while I still get cramping at my old ostomy site for the bowel was brought and attached there - but no pain.

[@Mjjfanforever988]

@@ronkemperful was your chronic constipation from the hirschsprung disease in your childhood, and usually when people pick up bugs, they get diarrhea and vomiting

[@blessych8821]

Tqq sooo much

[@dailydoseofmedicinee]

Hirschsprung's disease is a very serious condition. But if found quickly, it can almost always be cured by surgery

[@ZeroToFinals]

Nice summary!

[@remgroup8401]

My baby had this surgery at 6 months. Please tell me if hes gonna be ok

[@nessafinucane424]

My brother who just turned 31 had this . He had a couple of surgeries as an infant but he is completely fine ! I’m sure treatments have changed and improved @@remgroup8401 He will be ok - good luck with all !

[@marzosfammusician6127]

My baby had this disease now he's 4month old i do rectal irrigation 3x a day to stimulate his bowel that is the doctors advice and i do suppository also to lose his bowel. The pedia surgeon schedule his surgery until he gain weigth atleast 10kilos.

[@srisai9553]

How to find quickly and what are the Early symptoms

[@elafkhalid5319]

Give u like before watching the video cuz i know it’s gonna be amazing!

[@Evie-Hope]

My son is now 3 and this sure fits his symptoms.

[@SACHINSHARMA-kr2hy]

Hello mam

[@SACHINSHARMA-kr2hy]

Please provide your number i contact you because my son facing so many problems after operation

[@rathodnehal2869]

thank you sir for excellence teaching 👍👍🙏🙏😘😘

[@ZeroToFinals]

It's my pleasure

[@melsd2383]

Great

[@hkathayat]

Does this disease cause iron deficiency after corrective surgery? Is there any relation btwn them?

[@oakbongo]

I almost died of this in '98, 6 months after I was born. The doctor who did my surgery did the best he could but 21 years later I started having these spells where I would throw up bile uncontrollably for days. Usually it was when I was under intense stress, when I had my period, or when I performed high-level movement activities for a prolonged time. I was in and out of the hospital for three years in my early twenties until I almost died again and had to be held in a hospital for a month or so. I found out after my second surgery that my scar had healed and amalgamated with my intestines which caused all sorts of complications. That was few years ago, I can say it's gotten better even though never quite gained my weight back. I did get hospitalized again last year for a week but I think I can chalk that up to working 7 day weeks. I try to avoid stress as much I can now, and I white knuckle my painkillers during menstruation but overall with yoga, good nutrition and a shit ton of water, I think you forget about it.

[@droneorz1167]

Can someone xplain me the correlation between ganglion cell absence and nerve plexuces absence... In hirschsprung disease

[@krishnaveniparvathreddy1697]

Ganglionic cell absence leads to absence of relaxation where as nerve plexus absence leads to absence of peristalsis

[@ffionliz20]

My daughter wasn't diagnosed until 2.5 yes old. Was palmed off as constipation even though she had issues from birth and couldn't poo by herself. Had an ileostomy at 2yrs 10 months and having her pull through Dec 1st 2023 at 3 years and 9 months and her stoma reversal 6 months after. She's prolapsed twice already. I'm so dissapointed with her drs

[@fayekenamandhomoeopathy2621]

Fine.

[@mr.anilscreaction6088]

Osm video ❤❤❤❤

[@sittiemagao3474]

Why fever is one of the symtoms?

[@tituskiprotich1132]

Nice

[@gargmurari]

Dear sir, My son has undergone Hirschsprung disease second operation in June 2023. But still the constipation problem is persisting. i have read many articles in which they are saying that constipation problem will go away with time. and normal brawl movement may take 2-5 years. Please guide me whether after surget constipation is common for some time.

[@janstrakos9827]

Hi! Why the absence of neurons leads to the contraction? (I thought that the absence causes rather the dilatation) :/

[@hassansamore6063]

In this disease parasympathetic(which control relaxation of gut) ganglion nerve cells are absent. The sympathetic(which contract) nerve cells are intact. There is no opposing action which leads to contaction.

[@janstrakos9827]

@@hassansamore6063 Thanks 🤗

[@sujayc1642]

I was operated for this as 8 months old baby. Now I am all right. 23 year old

[@radhasree9509]

Is it ur symptom only constipation or any other symptoms and by using syrup also not went motion na please tell me

[@sujayc1642]

@@radhasree9509 i didn't get you, can you be more clear

[@radhasree9509]

@@sujayc1642 u got operated for this as 8months rgt suddenly got this disease or any other symptoms becoz my baby is not going motion From 2nd month to present 6th month healthy baby only not going motion if we use Dey's milk of magnesia syrup then motion will go now iam getting is my baby also might have this disease please tell me iam getting fear suddenly watched u tube video got tension

[@radhasree9509]

By using syrup will go motion other wise no

[@radhasree9509]

Please reply getting tension my baby healthy only motion will not go by using syrup only will go now getting u also tried syrup or not after using syrup u went motion or in childhood how u got to know u have this disease

[@traonnaaa8488]

I was diagnosed with Hirschsprung disease when I was baby and I was in and out the hospital but I don’t have it anymore I have a kinda long scar underneath my stomach but would this affect me from getting pregnant bc I really want a baby

[@bjamz3784]

My son is 6 months old and has Down syndrome and Hirschprungs disease. He goes in for surgery on the 21st April to see if they can correct is large intestine. Poor little man, it’s a real eye opener and he’s a soldier

[@kayshawnfoster5834]

I pray your son surgery is a success

[@aga5897]

Mastaaaah !

[@Noor-tz7xr]

my son suffering this disease, now my brain not working at the moments for this disease. my son age 38 days. then what can i do. i am Bangladeshi.

[@arminmanic553]

Did he made the surgery? How was it?

[@sumblasami6073]

After surgery it's there any complications????

[@srisai9553]

Enterocolitis

[@molleraw]

my daughter is one month old and has been diagnosed with this disease. she has the most severe case, they’ve done a lot of biopsy’s all over her intestines and have found ZERO ganglion cells 😔

[@bisolaaina6205]

I'm so sorry to hear this, I pray that your daughter experiences the healing power of Jesus.

[@sameertamboli4344]

Same My baby also found this.. please pray… How is your baby now

[@CaptivaLP]

It has to be difficult for americans/non-Germans to study medicine :D

[@dr.sadibinshams2367]

First comment! From Bangladesh 😊

[@ZeroToFinals]

Hello in Bangladesh!

[@rameybutler6555]

i was born with this in 1976, they didnt dianose it until i was two. i still have a massive scar across my stomach.

[@cemilr9648]

Please indi mene yazindan neceboldugunuzu menimde oglum bu xestelikden eziyyet cekir

[@zoesawchuk9932]

Just got diagnosed at 23 years old

[@cemilr9648]

@@zoesawchuk9932 indi necesiz ? Emeliyyat olunmusuz?

[@srisai9553]

@@zoesawchuk9932 is ur 1st diagnose for hd? Adult can get this problem?

[@enklare5343]

i had this in my body lmfao

[@farizanuraini5506]

Do they make a stoma for you?