How Do Cilia and Flagella Move?

[@dev5966]

the animation is so much better than a verbal approach to understanding this sort of thing thanks

[@almasfarooq9547]

The caption should be "Movement mechanism of flagella", yes Cilia and Flagella have similar internal structure but they differ in their pattern of movement.

[@jianfenglin7450]

You are correct regarding their different movement patterns. This video aims to introduce the Switch-inhibition mechanism shared by cilia and flagella with 9+2 axonemes for beating generation.

[@mrnerd73]

I'm very much overwhelmed to learn in the ways our older generations couldn't even imagine ❤️

[@us3rG]

They kearned things you jave no idea sbout too

[@MikaTok]

​@@us3rG any ideas how

[@andersnelson6888]

EXACTLY what I needed. Whoever made this animation is beautiful

[@rabiulhasaneee]

But whoever made this machine? It's out of the blue.

[@intensecutn]

​@@rabiulhasaneeeWho made the machine? The machine made itself, through genetic mutation and natural selection.

[@CherifHadji09]

​@@intensecutn that's god engineering

[@sporksto4372]

@@CherifHadji09 God only exists in your narrow mind.

[@CherifHadji09]

​@@sporksto4372 كي جيك ساعة فماك تفهم شكون لي مخو صغير يا سي طوني

[@WDCallahan]

This kind of stuff absolutely fascinates. It's great to be living in the future.

[@Zoooooooooooo]

we live in the present

[@inferno38]

You lived in the past

[@Chris-sv8ty]

Yo this type of shit has been going on for roughly 3.5 billion years

[@sporksto4372]

You clearly do not know what "future" is.

[@marcelnowakowski945]

Reading about this in the "Microbiology for Dummies". The video is very, very helpful. Good work - thank you!

[@waliaphellps1745]

Do not know what is more amazing: the reality or tha capability of getting to know all this mechanisims by human scientists.

[@voetius]

Everything perfect but for a thing: This is the eukaryotic flagellum. The bacterial type is totally different. Otherwise, a wonderful, clear and insightful animation.

[@jianfenglin7450]

Appreciate your comment. But when eukaryotic flagella are mentioned together with cilia, the word "eukaryotic" is often omitted for conciseness.

[@voetius]

@@jianfenglin7450Well, if conciseness is the key, then all stuff about dyneins and mechanisms so on has no place. However, I still believe it is the best animation available on the issue.

[@sankalpsharma9947]

best explanatory video ever

[@malikkazimkhan3681]

Excellent !! plz come again and again with such awosome and appreciable stuff..

[@mariamnegm7865]

greatly animated....❤

[@lilspacebunnny]

Such a good video thank u sm!

[@DerEpistokrat]

Wow, now I understand! Thanks. Especially the spatio/temporal coordination of Dynein movement is shown perfectly and correctly. There is one little mistake in it though, I think...(And I am only writing this in order to check my own understanding). The system would not work if all activated Dyneins "walked" synchronously, as shown in the animation. Because then the bent would immediately relax when they all let loose at once. Am I wright? Best wishes and thanks again for this beautiful and clear animation.

[@DBS608]

That's great work... Thank you

[@IvanBirb]

This video is the only reason I understand this concept

[@Crystal_Scott]

This was very Informative and visually appealing!

[@diyasoni8524]

Beautiful video, keep uploading such content 😊

[@NebulaTornado]

professional job.! I give you a win medal... thanks for this high level formation..

[@ElNietoPR]

Excellent! More videos, please!

[@ksaladin]

This is a superb video and lucid explanation that gave me new insight into this process and will be useful in my textbook writing in anatomy and physiology. I love seeing this application of cryo-EM to deeper functional insight. However, the video is titled "Mechanism of Cilia," yet speaks only of flagella. It leaves me wondering how much of this translates to, or would be different in, cilia. This is in light of the difference between the corkscrew motion of a sperm tail propelling a mobile cell, versus the cilia on a stationary epithelial cell (as in the trachea or uterine tube) undergoing a stiff power stroke and limp recovery stroke.

[@yougotsnipedbro6060]

Thanks I was wondering how was axoneme a part of flagella Great help

[@peterv4189]

Awesome video. Thanks. But I am thinking the opposing side to side firing mechanism illustrated would cause side to side bending, not up and down movement? Correct me if I'm wrong. Still amazing graphics

[@fratlows]

Yeah it must beat side to side

[@kannaiahk1848]

Super teaching

[@spreeze3468]

Me and my girlfriend will try the mechanism. Thanks!

[@Steve-vf7se]

It kinda moves like snakes...or electric eels. I like it, by the way, I want to see more of it. This is so cool

[@samgnanaraj]

breathtaking! The beauty of creation

[@sachinmore8376]

Amazing

[@icysnake1989]

It's a great job! Thanks!

[@daviddaniels3853]

This is a truly bad-ass video!

[@jeherulislam6903]

pleaSe include closed caption for HH

[@i.amnasim]

Rishab Sir❤

[@ina.v]

WHOAAAA u guys helped me SOOOOO muchhh

[@Muuip]

Great concise visual presentation! Very informative, much appreciated!👍

[@s81am]

سبحان الله الذي أتقن كل شىء

[@outkast334]

Excellent video and description

[@suneetsharma907]

BEAUTY

[@fabiopiras7642]

Thank you!!!!

[@SeanRhoadesChristopher]

Now, how does it know where it's going? It must have programing directing it to a target destination.

sperm chemotaxis

[@jeherulislam6903]

when u typed these letter, your actin and myosin doesnot know where o0r which way too fire, like that, their firing direction is dependant on other aspects of physiology( not brain per-se but chemotaxis or so

​@@jeherulislam6903 The movement of sperm is directed by chemotaxis; a biochemical pathway responds to concentration gradients of chemicals released by egg cells. It takes these oocyte-released chemicals as input, and the reactions we see in this video are the outputs. Imagine a simple little robot built to move in the direction of a stimulus (like light); the same thing is happening here. Without the stimulus (chemoattractants), the sperm would presumably just move around in random directions.

[@FutureAIDev2015]

Taurus Londoño So basically, the cell can smell where it’s going?

[@jeherulislam6903]

@@FutureAIDev2015 yes, for layman term something like guide by smelling. To understand how it works u need to dig deeper aspects of chemistry.

[@AnilkumarGulia]

Great stuff

[@ilkesar9841]

Amazing!

[@frankjaumajubert6124]

Don't the flagella move in a chorkscrew-shaped way making the action potential round?

[@thedisintegrador]

that's so in prokaryotes, in eukaryotes it's like this

[@greathornedowl1783]

No, you're thinking of bacteria like E-Coli and Salmonella. This is a sperm cell, a eukaryote, totally different organism.

[@ChrstphreCampbell]

how do atp's provide power, do they have to be there for each tiny, tiny, tiny action, or do they merely 'heat up' The general environment & allow chemistry to do it's thang. ( sic ) ?

[@MrFarber31]

lots and lots of ATP

[@avivayash4857]

amazing

[@Muuip]

Billions of years allowed life to create such complex systems and integrate them with many others to create living beings on one (or more) planet of this universe. Amazing!

[@KomalDua-s9v]

Amazingggg❤

[@maryamqussay1273]

thank you

[@imnayab7136]

Animation 💯

[@peterbuckley1794]

What was the bathroom flagellum

[@SAPANAACHARYA-gz2xm]

perfect>..

[@partyakshvatsal1301]

Amazing!!!

[@shalina356]

Nice. But the colour change confused me a little.

[@peterbuckley1794]

You can't stop me from moving

[@Ilovelimabeans]

A powerful example of intelligent design!!

[@shailjha3397]

Awesome

[@A3Kr0n]

No rotating motor?

[@agnelomascarenhas8990]

Left me confused. Bacteria have rotary motor coupled to the flagella. Our own cilia are back and forth motion like the one described.

[@RenatoPinali]

fantástico...

[@bradhilton2283]

If you have ever gotten baked off your ass and watched yo Gabba with a favourite nephew ....You are going too love get baked and watching cellar science animation.

[@AfifDidar04]

0:34 0:55 1:40

[@fabiopiras7642]

my brother

[@hassaneltras1579]

If it depened on action potential

[@username2516]

created , no doubt about it

[@meducla]

WOW !

[@gamingtilldusk6712]

Wow

[@danny1504-g2d]

oh my god

[@paulobichara3213]

God is a perfect designer that we can witness even in a fallen world because of sin. Mesmerizing

[@ina.v]

go girl my lion my bear my cilia

[@هدهدالشرق-و4ه]

روعه

[@Makeshiftjunkbox]

Electromagnetic plasmoid dynamos of the organism that is the Universe transmuted under high pressure not machines!

[@rimplekour3882]

👌👌👌👌

[@woofy9977]

totally just random chance of such design, right???????

[@benski0573]

it’s like a biological engine

[@RamanSingh-zf1cc]

This shi gets complicated

[@drkthemusicman]

so we were similar as sperm form??

[@ammarhaider1727]

GOD is the BesT

[@Hiteshbhatt-s5e]

And they say god doesn’t exist

[@sandinoblackmamba9174]

Result of Intelligent Design and not darwin's evolution.

[@agnelomascarenhas8990]

You should be studying the Bible or such creationism, don't waste time in science.

[@Tejano._.]

Fr سبحان الله

[@FLORIDIANMILLIONAIRE]

Nature indeed is intelligent at making micro molecular mechanisms

[@Lerenthial]

Interesting fact is that these micromachines working on molecular level evolve faster than your “spiritual lot” 😅

[@succulentravioli954]

Bro it's not that deep 💀

[@alsame9376]

More evidence of Intelligent Design. Molecular machines are the biggest and most blaring evidence of intentional design for an intentional purpose. All glory to the Creator.

[@SutliBomb-e4m]

Yes say that to a gay

[@mirfan-2020]

And who created this apparent creator who should be even more complex? If you're gonna say he always existed you have to prove it, as there are way better explanations with concise and plentiful evidence to support evolution and to disprove intelligent design. The intelligent design is a classic example of argument from ignorance.

[@FaridOmarzadeh-om]

@@mirfan-2020 it is like trying to teach monkey physics, the monkey will never understand physics - humans can not understand God as he himself says "The sights do not apprehend Him, yet He apprehends the sights, and He is the All-attentive, the All-aware." 6:103