How do different acne treatments work?

[@ritikaraghuwanshi8060]

Thats such a great explanation 👏

[@tsikinite]

I was wondering if you could provide any insight into topical tretinoin strength. I was able to achieve great improvement in my acne by week 8 of treatment with 0.025%. My scars and pigmentation faded by month 6. Unfortunately, I was advised to move up to 0.05%. Within a month, I suffered severe breakouts. Worse than I had ever had. I subsequently moved back down, and it has taken 6 weeks for my skin to return to its normal state. Although now I have lots of pigmented scars from the failed 0.05% transition. This experience had led me to ponder the role of irritation in acne formation. Clearly for me the 0.025% was sufficient to resolve my acne, and in extension any dose higher led me to breakout from irritation. -pre med student.