How Ricin Works

[@darkscienceyt]

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[@Username5H0]

I'll consider it.

[@AninomousUser]

I am in need of a wallet. Does the environmentally LWG certification mean the leather is non animal?

[@jayl5032]

@darkscienceyt Also Prions. Don't forget prions. Fuck those proteins in particular.

[@btbb3726]

Rice Krispies: OK Ricin Krispies: Not so much.

[@Adam-nv9zo]

That's why my ricin and gravy tasted weird. Well, now I know. 😂

[@btbb3726]

@@Adam-nv9zo You’re welcome! 😜

[@Paxmax]

@btbb3726 The worst part is that "Ricin Krispies" doesn't sound so bad... If you don't know ricin that is. Pretty funny gud sir!

[@UraTrowelie]

Lol. Nice.

[@the_ashen_one-t7e]

"I slipped it into that stevia crap you always put in your tea, goodbye Lydia"

[@gabrielbarrantes6946]

If the tea was hot it would have denatured the ricin...

[@mickmockedmack]

​@@gabrielbarrantes6946oh Walt. You done broke bad again - Walt Jr.

[@roberttrent4388]

​@@gabrielbarrantes6946hot tea isnt 176 degrees by the time it is served and you are putting sugar in it

[@myoldmate]

​@gabrielbarrantes6946 is that true? If so, can you give me links to verified studies that can confirm that.

[@Drummr88]

@@myoldmate If you're asking that question in a snide manner, then get bent. If you're being sincere though, then the guy is right - ricin breaks down at 176F. It's been well documented, and it's not even contested.

[@_P0tat07_]

We have 2 castor bean plants on the golf course I work at. The plants themselves are incredible. They grow very fast, and very tall. And have huge leaves.

[@christopherleubner6633]

Yup. When I was a kid I got one of the seeds stuck in my ear because a kid thought it would be funny to shove it it because they looked sorta like big fat ticks. Had no idea they were toxic.

[@geradkavanagh8240]

In the area I live, castor bean plants are everywhere and considered a weed. But unless your specifically employed to remove them you are advised not to touch them.

[@smashlee6181]

@@geradkavanagh8240 eh, just don't mess around with the seeds. I've pulled heaps of them and never had any issues.

[@Leviticus777-us4cg]

FBI OPEN UP!!!!

[@oumardiop1]

Haven't finished the video yet so: who asked Will update once this becomes relevant

[@krimzon7622]

I loved it when Jesse and Walt said "It's Ricin time" in Breaking Bad and Ricined all over the place.

[@ilmorifajt4092]

I hate you, liked.

[@ranhny2022]

Please leave and thanks

[@aichrist]

Rice and beans

[@TheZvedak]

Walter

[@koftespiess]

I just knew a comment like this was inevitable lol

[@stellarwind1946]

Ricin was made infamous by the Markov assassination, and permanently ingrained into pop culture by Breaking Bad.

[@geradkavanagh8240]

I knew about ricin long before 'Breaking Bad'. It's a really nasty substance for short and long range chemical warfare. No immediate effect, just huge deterioration of people exposed in a few days.

[@sepg5084]

We watched the video...

[@phillipdavidhaskett7513]

There's an episode of the original CSI where Peterson is investigating a murder using Ricin-D Nitrogen (the proper chemical name of the toxic component) and speculates that the perpetrator "cooked up" some in her kitchen before the crime. That was a nice bit of misdirection since applying heat to the molecule destroys it, which is why the pulp of the castor bean is steamed after the oil is extracted. I loved the smell of real Castrol brand castor oil in my 1972 Kawasaki 350 triple, which had a separate tank for the two-stroke oil automatically mixed into the fuel before combustion. I don't even think they sell that anymore.

[@soonlytaing1708]

Hi, noticed a small error at 7:27. Ricin is not hydrophobic but I think you meant hydrophilic or lipophobic. Anyway, great video

[@robertnichols2283]

That’s what I was thinking

[@TojiFushigoroWasTaken]

i was thinking the samw thing too

[@joshuasalem5022]

Yes you’d be correct

[@Sr.DeathKnight]

Somehow, I understood lipophobic.

[@Nicksory]

this video is full of errors :)), how can enzyme A cause havoc on the cell from outside of it when the grains enzyme A also are out of the cell, details are missing , i'm MAD

[@TheBioCosmos]

Just some corrections to the video: 1. Obviously, ricin isn't the only toxic protein. Many venoms are protein-based too, so there are many toxic proteins we would want to avoid. 2. Ricin is hydrophilic, not hydrophobic. If it's hydrophobic, it would be able to dissolve in oil.

[@Sr.DeathKnight]

Thanks.

[@UncommonLtd.]

Damn....schooled the schooler

[@Mangaoreader]

I was looking for this comment, surprised no one mentioned this

[@alexweschler9470]

Point 2 brought me here

[@ncedwards1234]

Scrolled too long to find this lol.

[@Laggu]

When two ricin toxins love eachother very much...

[@babycarrotz32]

😳

[@Ultra.1508]

This is the only KZbin channel that has captivating science videos that are interesting please keep doing these beautiful videos.

[@darkscienceyt]

Thank you!

[@AninomousUser]

Yes I agree your videos are so simplistic with good information and just the right amount of humor

[@LegoTechnicsRule]

NileRed: Excuse me!?

[@doaimanariroll5121]

I mean this is a good channel but come on bro. Steven mold, alphapheonix, science asylum, Nile red to name a few.

[@shroomyk]

Aw you won't tell us how to make our own at home? Part of learning is the hands-on experience! 😂

[@fionascookie9598]

It made me laugh when he said it hahaha

[@spvillano]

I guess we'll just have to stick with our youtube home brain surgery course.

[@TheRacingRoo]

always a good day when dark science uploads

[@Ucceah]

it would have been worth mentioning, though, that extracting pure, intact ricin is a rather difficult and laborious process.

[@nalgas5569]

Please tell me more you chemistry guru

[@myoldmate]

​@@nalgas5569I have difficulty determining whether this is a snarky comment or a genuine question.

[@mymobilebuddy4392]

@@myoldmate In Kansas a doctor tried to kill her husband with this. It harmed his brain. He survived.

[@lynnlard5531]

​@@mymobilebuddy4392 That (the book "BITTER HARVEST" by Ann Rule) was how I initially learned of Ricin. Though the husband did survive, I think one or two of their children did die in a fire she started.

[@ncedwards1234]

@@mymobilebuddy4392 Sounds easy then

[@ranmakb]

Finally, another Dark Science video!

[@topquark4208]

Science is never boring.

[@Nanamowa]

I wonder if we could use the B-Toxin as a drug delivery method to get medicine inside cells. Perhaps we could make it so a modified version of the A-Toxin is able to be disabled by healthy cells, but not cancerous ones. Also, perhaps we could find a human-specific enzyme and modify toxin A to bind to that enzyme and disable its toxicity, allowing the toxin complex to act as a universal antibiotic/fungicide allowing a cure for nearly all non-virulant infections.

[@CrestedSaguaro520]

I'm late by 11 months... But this is absolutely genius. You have a great idea and it would definitely be possible! My, that would help millions of people. 😃

[@babycarrotz32]

Another video! I love your simple and concise videos. Super fun to watch. As a suggestion, could you look into misfolded prions, or rabies?

[@darkscienceyt]

Believe it or not that's on my list!

[@babycarrotz32]

@@darkscienceyt If you do prions could you talk about tropes in shows and games that misfolded prions cause zombification?

[@abqmalenurse]

Castor oil is also used as a plaster mold release agent. You can buy it at home improvement or arts and crafts stores. It has been deactivated. In the US, castor oil laxatives are hardly ever used or available any more. When I was a kid, a common brand was Fletcher's Castoria.

[@Irish381]

Benito Mussolini used castor oil to torture his political prisoners, they were force fed the oil and left chained. The results were that the victims died from diarrhea and dehydration. No need for a special poison.

[@bamahammer949]

Not the same thing

[@franzpattison]

"Rice and beans Mr White what the hell?"

[@mohammadhananshah]

kzbin.info/www/bejne/hqO4ZYqmm8-ojbssi=R71_qI-lzYl0yC_m

[@gaeshows1938]

Not to be confused with rice

[@Handle4511]

I love this comment 😂😂😂

[@ColinKelsey]

Now that is a buqe of woops e daisies

[@nandomkpot420]

👹

[@user-di7tg7qf6u]

Too late…

[@StkyDkNMeBlz]

That's why we wash our rice first before cooking it

[@eltiobry3859]

Amazing video, I loved it, very informative, interesting and just the right amount of humor, thank you ❤

[@mitchellrobinson3814]

Honored to be on a list with all you gentlepeople.

[@atlanciaza]

It's so easy to find out how to make it, so I would think it would not be a problem discussing it.

[@moiraatkinson]

Great video! You have an excellent way of explaining things.

[@darkscienceyt]

Thanks!

[@mathewsphiri5629]

Locally called kalibgonda, those beans have a deadly rep. But people still eat em

[@lx_9696]

At 7:26 I think it's meant "hydrophilic". Because then it makes sense, that it doesn't dissolve in oil

[@lx_9696]

Similarly you can also say "lipophobic". This way it exactly means, that it can't bind to oil

[@Tishers]

As a child my mom would administer a spoon full of castor oil to relieve symptoms of constipation. It was vile and disgusting tasting. I later ran in to it as a lubricant for tiny (radio controlled) airplane engines. Just the smell of that oil was enough to bring back unpleasant memories of its taste. It was really interesting how you explained the biological hitchhiking of the two proteins to gain entry in to a cell.

[@chrissanders2562]

I loved when Walt and Jesse used ricin to explore Connecticut!

[@haythamheinrichsaeth264]

HE CAN'T KEEP GETTING AWAY WITH THISSSSSS

[@robertmurray8815]

Censorship sucks big time.

[@giovyn3ss364]

Your video quality is extraordinary, keep it going🎉

[@starwarfan8342]

Breaking Bad stans are about to invade this whole comment section

[@nukesrus2663]

too late

[@MrMa1981]

YES SCIENCE!!

[@therraxz]

Had atleast 3 cases in my country where people made it. One case it might have been suicide the other 2 was probobly curiousity/terror. But no innocent was killed in any of those 3 cases.

[@gerryst-aubin5877]

If ricin is "hydrophobic" it is "water fearing" and thus should be quite soluble in the castor oil. If, on the other hand , ricin is "hydrophilic"" or "water loving" it would be soluble in water and thus not be present in the castor oil.

[@blackhatvisions]

Bro's videos are 30% ads and 60% sponsor

[@MysteriousFuture]

Gotta get that bag 😂😂😂😂

[@sciencenerd7639]

Wow, fantastic video as always. I love this kind of content.

[@eliasl332]

There always is a delay from the time you upload and the time I find the video. This time it was 5 days.

[@trevorrichard4710]

Look at the wonders of the body. Think about all it takes to keep us alive. Mind blowing 🤯

[@RealBelisariusCawl]

Hello everyone. It’s nice to be on a list with you all.

[@EREANX]

Sir You Really included that breaking bad scene into your video Respect + Because I clicked this video because of significance of breaking bad

[@azraelwai]

Bruv didn't shared the information which I was waiting for till then the end. :"]

[@mikelchu100]

What if I bought Castor beans on Amazon and ate them

[@nukesrus2663]

It would be funny I think

[@dr.karmichaelandjones]

2:44 Why Eric Andre? 🤣🤣🤣

[@darkscienceyt]

Why not

[@dr.karmichaelandjones]

@@darkscienceyt Your logic is flawless

[@TheSleepSteward]

Welcome ladies and gentlemen; we are now on an exclusive list. We are truly, MVPs.

[@Tendies7645]

Hello watch list buddies

[@tamekkaknuth9612]

Love black friday its christmas shopping time

[@DeyvsonMoutinhoCaliman]

There are many proteins in plants that are toxic, but they are mildly toxic, you would have to eat a lot to have maybe a stomach ache or diarrhea. Just point out that it's not only one protein you better avoid. One example is lectin, a toxic substance found in many plants, many that we eat, but cooking the plant decrease its toxicity by a lot.

[@noname8354]

There was apparently a ricin attack in 1981 that happened 5 minutes away from where I live as well. Not as well-known but still fucking awesome

[@SirLukedatgoat]

YEAH SCIENCE!

[@Nubenhoofer]

I always picture Beavis saying "Heh heh, RICIN. RICIN. Heh heh..."

[@b2617]

Science is crazy thanks for the videos

[@gabrielbarrantes6946]

In breaking bad, if the tea was hot (most likely close to 100°C, water boiling point) that would have denatured the ricin... Or was a cold tea?

[@senorpepper3405]

Nunya

[@liamholcroft7212]

tea is typically 60 degrees, you wouldn't be able to drink it if it was much hotter

[@RedfishCarolina]

2:40, Protien A struggles to enter green eggs, because there is no ham for Protien B

[@lammie001]

Expected a lot more from this video.

[@JatPhenshllem]

What else did you expect?

[@nukesrus2663]

@@JatPhenshllem Instructions

[@JatPhenshllem]

@@nukesrus2663 Expected a less weird response

[@bilalkhabir5873]

As a kid I used to play with the seeds of the plants from which it is extracted

[@8Mev]

"I am not going to tell you how to make ricin... But make not mistake, I know how to do that."

[@pagisha]

Pls tell

[@GreatLakesDrifta]

Lydia oh Lydia, Lydia my Lydia, Lydia the tahh-toooed lady!

[@jordanaddiction419]

Please talk about smoking next and what it does to damage cells.... Like heavy metals in brain and the reasons to stop please man

[@GG-ms4qp]

That's more of a moral thing not science thing, as I have seen couple of 90+ years old people smoking everyday

[@spvillano]

Heavy metals, CO, CN, but the worst is the hypertension that damages the blood vessel walls. Now, excuse me while I get a cup of coffee, then have a smoke for a double whammy on my BP. Oh, the single greatest cause of failed back surgery? Smoking. It's a vasoconstrictor. Slows healing. My biggest health issue is BP related, but not to smoking. Hyperthyroidism and a few thyroid storms, which have done far more damage than my coffee and smokes ever could. I know the risks, I understand the pathophysiology, it's my choice. But, if it's any consolation, as much as I loathe my own secondhand smoke, I loathe exposing others to it even more.

[@bigbluebuttonman1137]

Waltuh Put the ricin away Waltuh

[@pomi1298]

7:20 hydrophobic = lipophilic, means it dissolves in oil, not water.

[@Real_Chara_Dreamur]

I’m curious if you would be willing to make a video on Inhalants?

[@WolfmanTVReal]

omg a new video

[@kaischreurs2488]

7:25 wouldn't being hydrophobic make it dissolve well in oil while not dissolving in water?

[@jozefnovak7750]

Super! Thank you very much!

[@claudioclaudio7953]

You didn't mention the use of castor oil by the Italian fascist regime :(

[@markiangooley]

The Communists eventually copied the Fascists and both sides used it: although the Fascists gained the upper hand and controlled the country for a long time, after the war the Communists had some popularity in Italy. See the Don Camillo stories by Guareschi, set mostly in the Po Valley of postwar Italy. Both people who missed some aspects of the Fascist days, and the Communists, copying the tactic, would send a group of men to force an opponent to drink a big dose of castor oil, with unpleasant consequences. Fortunately, castor oil isn’t toxic. I don’t think I’ve consumed any unless it’s a minor ingredient in something popular.

[@NathanBrown-z7o]

I'm not evil but, I know how USA castor oil torture is evil.

[@thedude5661]

yeaaahhh rice and beannnsss

[@beryllium1932]

Stevia by Ricinberg ☕️

[@rutgers182]

soy, rice + beans or rice + lentils are also complete proteins

[@hellmm5195]

How can rice and beans kill you?

[@furonwarrior]

Anything can and will kill you.

[@babycarrotz32]

@@furonwarrior Idk man. That paper plate in my room is kinda passive. Tells really good stories too.

[@endlessunivese9350]

this is why many power house users like gym member don't last too long before they become debilities

[@CloudyBogdan]

Good video to end today :)

[@csisver]

rice and beans

[@ThatScootFanboy]

Alright, I've said similar stuff in your comments before, but I think it's time for round two. Are we seriously at a point in which you have the sensor the words 'weapon' and 'assassination'? Un-fucking-believable.

[@salarkhan9885]

U sound upset mate 😂

[@ThatScootFanboy]

@@salarkhan9885 Because I am. Cheers for your expert analysis.

[@Benny-jt9cj]

Blame KZbin buddy. Content Creators either do that or get their videos demonetized.

[@assoartisticworld]

Thank's 👍🏻

[@darkscienceyt]

sure

[@tcpnick6895]

Wait Ricin is hydrophobic but doesn't dissolve in oil? Am I missing some chemistry knowledge or was that a mistake?

[@darkscienceyt]

Yeah, error on my end, I meant hydrophilic

[@christopherleubner6633]

It is extremely hydrophilic, this is actually one reason it has not been weaponized other than for special uses like assination as mentioned in the video.

[@NathanBrown-z7o]

Don't mess with castor bean's.

[@rickkwitkoski1976]

Absolutely wonderful Thak you

[@Captain-Nostromo]

There is a face in the Mushroom Cloud 8:11

[@MrEpsilon69]

Breaking bad moment

[@jnllllllll6245]

for legal reason, i watch this video because im eating alone and I can't handle the loneliness while i chew my food

[@AhBehThe]

I would love a video about drowning death.

[@HellOnWheel]

Scanning titles as I scrolled, I thought it said "the dark side of ricin" and thought, there's a good side?

[@spvillano]

Yeah, the ricin prevents animals from eating the beans.

[@agooglygooglr]

7:24 Don't you mean hydrophilic?

[@darkscienceyt]

Yeah I flubbed that in my notes

[@mohitbeniwal7581]

Is anyone explain how's ricin is made?

[@WaterCat-pq1nu]

Inconceivable

[@realeyesrealizereallies8654]

Ricin beans anyone? No? Shout out to Jesse 😅

[@CSSuser]

The OGs know of ricin from "The Jackal" with Bruce Willis.

[@stevencooper4422]

I miss Bruce Willis I hope he is spending his final days well...

[@CSSuser]

@@stevencooper4422 yeah man, shitty illness to get. :(

[@rusty-dy3gz]

Its amazing how simply complex our podies our.

[@Joshify51]

Sometime could you cover radiation poisoning

[@darkscienceyt]

Oh trust me, its in the list...a very long list

[@aMh3c9]

1500/min? Enzyme reactions are so much faster than I thought

[@darkscienceyt]

There's over 1 quadrillion enzymatic reactions in your body every second 😉

[@keithallen5795]

Mankind can be horrific

[@ajitp3756]

Ricin is popular in Poirot series.

[@TheHighborn]

Actually I want looking for this video. It was recommended. It was interesting tho

[@Monicaruthcw]

✨ engagement ✨

[@santokr5323]

Please explain how to extract ricin in next video

[@bayraktarx1386]

I'm not a professional but I assume it would work just like any other protein you can find in meat, grains etc just need to get them in powder form.

[@NovaInquisicaoGN315]

I remember to play shooting castor beans on my friends 😂. Actually, it wasn't the seed.

[@briantaylor9285]

Scary stuff. 👀

[@ToxicMrSmith]

I know about ricin from a certain cookbook...

[@mastershooter64]

Rice and beans

[@Soljarag5]

I love rice n' beans

[@darkscienceyt]

I love this