HSCT Treatment for Multiple Sclerosis Patients

AHSCT RUSSIA [hsct-russia.com/]
It's a complex treatment program against Autoimmune Diseases such as:
- Multiple Sclerosis (MS)
- Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
- Ankylosing Spondylitis (AS)
- Neuromyelitis Optica Spectrum Disorders (NMOSD)
- Rheumatoid Arthritis (RA)
- Nonspecific Ulcerative Colitis (UC)
- Stiff-person Syndrome (SPS)
- Systemic Sclerosis (SSc) Scleroderma
- Systemic Lupus Erythematosus (SLE)
- Psoriatic Arthritis (PA)
- Myasthenia Gravis (MG)
- Sjögren's Syndrome (SjS)
- Crohn's Disease
The essence of the method lies in the elimination of a defective immune system with its subsequent reset.
Our unique method allows to completely eliminate groups of autoimmune cells and affects the mechanics of their appearance.
This approach may stop the progression of the disease and prevent further decrease quality of life.
In total, patient has to stay in the department for about 30-40 days to undergo a whole cycle of diagnostic and therapeutic procedures.
We use non-myeloablative protocol based on Cyclophosphamide 200 mg/kg b.w. and Rituximab.
The effectiveness of HSCT depends on MS variant, MS duration, and disability level, rate of progression, age.
The rate of MS stabilization and improvement for RRMS - 85-90%, for PPMS/SPMS - 70-80%.
The rate of MS stabilization (long-term remission) during follow-up period for RRMS is 90-95%.
We observed life-threatening side effects in less then 1% of patients, and have transplantation-related mortalities less then 0.5%
Our accumulated experience is over 17 years of follow-up applying stem cell transplantation to the treatment of autoimmune diseases.
In total, more than 3000 patients (half of them are from abroad) underwent this therapy with autologous hematopoietic stem cell transplantation in our Department.
"The National Medical Surgical Center named after N.I. Pirogov."
National Scientific Facility belongs to Federal Strategic Objects and located on the closed area on the edge of Moscow City. Fully autonomous medical complex consists of eighteen specialized departments supervised by own maintenance infrastructure - it's like a small town in a big city, that provides high-quality medical care based on the use of modern high-tech methods of diagnosis, treatment, rehabilitation and prevention.
An unique opportunity to solve most health problems in one institution, using, above all, a comprehensive approach to the treatment of diseases and the well-established interaction of highly qualified specialists by almost all the main directions of medical science.
The accommodation standards and quality of medical care in the Department are at least equal to those of leading American and Western European medical centers.
Aseptic boxes - separate chambers equipped with special air and water purification systems designed for bone marrow transplantation in a wide range of diseases (lymphomas, myeloma, leukemias, lymphogranulomatosis, etc.), treatment of patients with severe immune system disorders, which reduce the risk of infectious contamination patient with microorganisms.
The water and air purification systems - ensure a constant supply of sterile air and water and are an integral part of aseptic boxes
Cytapheresis systems - high-technology devices for collecting stem hematopoietic cells, red blood cells and other blood elements necessary for bone marrow and stem cell transplantation in a wide range of diseases.
The team of the clinic, taking care of the patients' health every day, sincerely believes that transplantation of peripheral hematopoietic stem cells is the way to your recovery.
Complete our questionnaire, describing your previous treatment and current functional status, to define whether HSCT is a meaningful and safe treatment option for you.
This online form must be accompanied by the report of last MRI (Please attach only report, no MRI images are required)
Link to the application: hsct-russia.co...
E-mail: [e-mail]
Facebook page: / 4multiplesclerosis
Facebook group: / 404629779644453
Instagram page: / ahsct_russia
Twitter page: / ahsct_russia

[@almendraantero-clopez9138]

1000% recommend the Moscow facility. Such a care dedication to patients ..! great team and a great hospital

[@annablennow3889]

My friend has ms, how much does it cost?

[@chrisismail]

​​@@annablennow3889 its about $50,000 USD my wife had it around 5 yrs ago, we are Australia and did fundraising for most of it.

[@almendraantero-clopez9138]

I’m so sorry I missed your question. For me it was aprox 53000$ cause I had to change dollars to euros to pay for it. I did it on 2022 when it was 45000 euros but right now I think it is 50000 euros.

[@evaneoskowar8859]

@@chrisismail is she healed?

[@chrisismail]

@@evaneoskowar8859 she is still in remmision, and stable . Stress can make symptoms temporarily worse like the pins and needles tingling . Then they decrease. At it's been over 5yrs now

[@LeeBarberMcrUK]

❤ I am forever grateful to Dr F, Anastasia and the rest of the team, thank you so much ❤

[@angelbabycards3595]

Honestly, It is now irresponsible to see a myriad of people, experiencing efficacy with HSCT, but the procedure continues to be denied in the US, literally for at least One Decade. Meanwhile, people such as Sandra Blair, simply spend a week or so in Russia, they come back, they begin to return to near normal function, dance on Dancing With The Stars, while the rest of us here in The States, prepare for Wheelchairs and Hospital Beds. Question: Is this truly the 1st World Country you thought it once was... ?? Getting ready to gather the cash I need to have the stem cell procedure in Mexico, and that's that! 😊

[@dominikpesut7498]

Hello, afflicted with MS myself, what is the cost of the procedure in Mexico, can you bring a family member with you?

[@shadow03clb]

They do it at northwestern in Chicago. That's where Selma Blair had it done. It's just not covered by insurance.

[@ahoarsewithnoname]

@@shadow03clb Do they? I thought they stopped offering it when Dr. Burt left? Tisch in offer it also.

[@AHSCT-RUSSIA]

For all those who like to compare commercial clinics with university hospitals) hsct-russia.com/Protocol-comparison @@dominikpesut7498

[@andrewkrivoshein123]

Thank you very much, you gave the second chance to live!

[@evaneoskowar8859]

Is the procedure faisable with a nail mycosis?

[@AHSCT-RUSSIA]

You should treat all types of infections before HDIT with AHSCT (more info: hsct-russia.com/before-treatment)

[@ElliesLittleMay]

Watching that brought back amazing memories and seeing the staff that gave me a second chance at life brought goosebumps. Thankyou to everyone, you were amazing. Yes it’s tough, but don’t hesitate! Get HSCT as soon as you possibly can x

[@proudman6651]

You did it for MS?

[@sparkywanderer3405]

I'm 26 years old, I was diagnosed with MS the previous year. It was acute & out of no where.. Even till now in the my medical records MS is mentioned with a question mark (?) My doubt here is do I have MS and have to continue the medication and is it suggestive to take this treatment as mentioned in this video.... please respond

[@AHSCT-RUSSIA]

This treatment is appropriate if your neurologist officially confirms the diagnosis of Multiple Sclerosis.

[@ryancarberry12]

This hospital changed and saved my life. It took me out of a wheelchair. The greatest of thank you from Ireland, I love you all.

[@leonardnardi9528]

How long is this treatment in hospital and after this treatment how long you have to stay isolate ?

[@ryancarberry12]

@@leonardnardi9528 Hello there, You check in to the hospital for a month, and when you leave you have the immune system of newborn baby. The first 3 months are very important each month you need to get bloods just to make sure everything is working as normal. A fellow up MRI scan is needed (full spine and brain). I sent my scan over to Dr F and he will tell you if there are any new lessons. I'm over a year home and relapse-free no more medications. HSCT is a gift.

[@proudman6651]

@@ryancarberry12 happy for you Ryan. Hope you can have a long relapse-free life. I am trying to know more about HSCT as an effort to save my brother’s life as he was diagnosed with Behçet’s disease. Wish me luck

[@ryancarberry12]

​@@proudman6651 Hello there give the hospital an email and ask if they would/have treated for behçets disease. I wish you and your brother the best outcome.

[@proudman6651]

@@ryancarberry12 wish you the same 🌷

[@archibaldplum5171]

I went through this a few months ago. The immediate side effects of treatment weren’t nearly as rough as I’d been expecting, and I’d pretty much recovered to baseline a month or so after I got back. I’m now feeling better than I did before I went. Still too early to say if that’s going to last, but its looking good so far. I’d recommend a trip to Moscow for pretty much anyone with RRMS

[@3meera43]

Hi, I’m really considering doing this treatment. I’m in my begging of my MS. However, I’m concerned about the mortality rate. This the thing I’ve been thinking of all the time. After a lot of research there is people died from HSCT. And there is 2 cases happened in Moscow in 2020 even though the success rate for others was high and changed their life!. Idk about after that date if they got more mortality. From your perspective would you recommend it to me?

[@3meera43]

@@proudman6651 Thank you I appreciate your comment. I agree with you!

[@proudman6651]

@@3meera43 best of luck brother. Wish you a full recovery and all those battling with such diseases. My brother has his own battle with Behcet’s which can be more awful in many ways.

[@3meera43]

@@proudman6651 Thanks, wish your brother a great recovery. I hope you guys one day you will find a cure. I fell you we’re in the same boat. Many prayers for him 🙏🏻 We must fight!

[@proudman6651]

@@3meera43 thank you brother. Wish you the best as well. Yea, same boat sailing against the wind. For MS, treatment sounds more promising. I’ve talked to someone from my country who managed to stop the medications after 4 years. He is doing great 8 years post medications. Sadly it isn’t the case with Behcet’s. This disease is awful and there isn’t any protocol to deal with it. Lots of prayers for both of you 🌷

[@proudman6651]

Do you do a non-myeloblative or myeloblative procedure for autoimmune diseases?

[@AHSCT-RUSSIA]

Non-myeloablative Sincerely Yours, Denis A. Fedorenko MD, PhD, The A.A. Maximov Department of Hematology and Cellular Therapy, National Pirogov Medical Surgical Center, 70 Nijnia Pervomayskaya, Moscow 105 203, Russia

[@chrisismail]

Great facility would highly recommend DR F AND TEAM ARE AMAZING! MY WIFE HAS BEEN STABLE FOR JUST OVER 3 YRS

[@bcviking9381]

Thanks for the feedback , im really wanting to do it .

[@AHSCT-RUSSIA]

Thank you, Christopher, be healthy and happy!

[@SunnySingh-rn9nm]

Hsct will stop m.s.completly or it will stop the progress?

[@chrisismail]

@@SunnySingh-rn9nm generally halt progression , but you may have a reduction in symptoms also.

[@peterjaniceforan3080]

🇷🇺😳think I’ll try 🇲🇽👨🏼‍⚕️

[@manjumehra8493]

We are coming from India what is the full cost of the treatment for primary progressive multiple sclerosis sending out reports

[@proudman6651]

Do you do this procedure for Behçet’s disease?

[@AHSCT-RUSSIA]

Yes, contact [e-mail]

[@naglaaahmed5325]

Can HSCT treat transverse myelitis?

[@goodgood660]

I have MS and I have a chronic headache. Is chronic headache a symptom of the disease? Please reply

[@wissembenmlouka8364]

I really have trouble walking ; I fall a lot because of losing balance and spasticity. Does HSCT remove all of that ? please help..

[@emilybarrett464]

I have RRMS, was on mavenclad for 2 years… new lesion on the brain so im going for HSCT, and i have read in some cases it can reverse some disability. I dont know if that means remyelination, but my neuro said its a very high efficacy treatment. Wish you all the best xx

[@emilybarrett464]

@@nancycarlos5695 im glad you found something that keeps your condition under control. Unfortunately there isn’t a cure for lupus, just symptomatic treatments. I wish you the best. Just be careful if you’re paying people online who claim to cure these conditions xx

[@evaneoskowar8859]

@@emilybarrett464 did you do it?

[@elenadolgikh3233]

Самый замечательный врач! Он меня вернул к жизни!

[@AlanzyAlsgrry]

Did you do the operation?

[@AlanzyAlsgrry]

Did you do the operation?

[@mama-iyad9192]

شحال تسقام بسواردنا ..لجزايري ودخل شاف تعليقي يجاوبني

[@zzoubir6473]

حوالي مليار

[@KH_SEP]

مهتمة

[@estherkollen4351]

Peer!!!

[@BattlesCinematics]

I'm 29 years old and still fully able to walk around all day long without any assistance, despite this, I've been having many symptoms of MS and most likely PPMS, I am just waiting on my MRI test results. Is there any data anywhere about how effective HSCT is for a younger person with PPMS who has not yet suffered any major disability?

[@AHSCT-RUSSIA]

The rate of MS stabilization and improvement for RRMS - 85-95%, for PPMS/SPMS - 65-75%. Early transplantation - is most effective. We suggest, that the best candidates for transplantation are relatively young patients with active inflammatory lesions of relatively short duration and rapidly progressive disease, but still low disability scores, resistant to conventional therapy. Cumulative incidence of disease progression was quite low both for RRMS and PrMS. After you would receive your MRI report (no images required - only report), proceed to complete questionnaire, describing you previous treatment and current functional status, in order to define whether HSCT is a meaningful and safe treatment option individually for you hsct-russia.com/application-for-treatment

[@emilybarrett464]

Does anyone know when this was filmed?

[@AHSCT-RUSSIA]

EBMT TV crew filmed this video around March 2022

[@bcviking9381]

Can i still get to Russia from Canada to have HSCT ? I know lots is going on right now with politics ?

[@AHSCT-RUSSIA]

Yes, you can. It will take 3-4 weeks for visa. Flight remains as usual, with connection in Dubai or Istanbul or else.

[@bcviking9381]

@@AHSCT-RUSSIA Thank you so much for the reply! I will be contacting you guys soon . I have been to Russia before for business .

[@KseniaMira]

@@bcviking9381 приезжайте! Мы готовы всегда помочь 🙂

[@zoharayosef287]

Do you do non- myeloablative or myeloablative?

[@ari-jv]

Can you use this for Lyme disease

[@AHSCT-RUSSIA]

- Multiple Sclerosis (MS) - Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) - Ankylosing Spondylitis (AS) - Neuromyelitis Optica Spectrum Disorders (NMOSD) - Rheumatoid Arthritis (RA) - Nonspecific Ulcerative Colitis (UC) - Stiff-person Syndrome (SPS) - Systemic Sclerosis (SSc) Scleroderma - Systemic Lupus Erythematosus (SLE) - Psoriatic Arthritis (PA) - Myasthenia Gravis (MG) - Sjögren's Syndrome (SjS) - Crohn's Disease

[@bg5760]

Look at msc IV infusion for Lyme

[@ari-jv]

@@bg5760 they said it causes death ☠️ 40% of the time

[@SeventhSky1]

What about Sjögrens ? Does it work for that too?

[@manjumehra8493]

Can ppms be treated with this treatment

[@AHSCT-RUSSIA]

Yes

[@cactusforever7198]

Do you do stem cells for knee osteoarthritis ??

[@AHSCT-RUSSIA]

No, unfortunately it is not suitable for knee osteoarthritis Sincerely Yours, Denis A. Fedorenko MD, PhD, The A.A. Maximov Department of Hematology and Cellular Therapy, National Pirogov Medical Surgical Center, 70 Nijnia Pervomayskaya, Moscow 105 203, Russia

[@leonardnardi9528]

That’s is mieloablative or non????

[@AHSCT-RUSSIA]

Mieloablative

[@manjumehra8493]

How many days of treatment and what is the success rate as she is completely bedridden

[@AHSCT-RUSSIA]

In total, patient has to stay in the department for about 26-30 days to undergo a whole cycle of diagnostic and therapeutic procedures. The effectiveness of HSCT depends on MS variant, MS duration, and disability level, rate of progression, age. The rate of MS stabilization and improvement for RRMS - 85-95%, for PPMS/SPMS - 65-75%. Complete our questionnaire, describing you previous treatment and current functional status, to define whether HSCT is a meaningful and safe treatment option for you. Link to the application: hsct-russia.com/application-for-treatment

[@manjumehra8493]

How do I send you her reports

[@AHSCT-RUSSIA]

Only 1 report required (Report about the latest MRI, no images, only report) you can attach it directly in the application form by the link hsct-russia.com/application-for-treatment

[@fastcashforex]

Anyone knows the cost of this treatment?

[@amandaolivier1351]

Roughly $55K USD. hsctmexico.com; hsctrussia.com

[@Eliza-yo7cb]

47.000euro. I will go next week

[@afifatunnisa7246]

Isn't it 50k?

[@3meera43]

@@Eliza-yo7cb could you give us update after your treatment plz.

[@chrisismail]

​@@afifatunnisa7246 around 50k usd

[@abtreeguy]

Recently diagnosed rrms, I gotta ask…. How much?

[@amandaolivier1351]

Roughly $55K USD. hsctmexico.com; hsctrussia.com

[@Eliza-yo7cb]

47.000euro

[@abtreeguy]

@@Eliza-yo7cb thanks I won’t be getting that 🤷

[@DanielOM-zo8fv]

I wonder which one is better Mexico or Russia to do HSCT.

[@amandaolivier1351]

They have roughly the same success rate and both have low mortality rates. I went to Mexico for HSCT. It saved my life.

[@МарияИванова-ю2т]

I don’t think we can compare these two facilities. They both have got different treatment protocol and the Moscow clinic has far longer experience treating autoimmune diseases. I would say they’re the leaders of HSCT so far.

[@brendakerber7923]

turned me off at 1:08 - MS does not 'inevitably bring the patient into a wheelchair' I know lots of people who have MS who do not use wheelchairs. I don't believe this will happen to me either. I can walk relatively well with minimal assistance - I am on an effective DMT. I don't believe there will be much progression. I have a friend who has been diagnosed 30 years. She rarely uses walking aids. My moth is diagnosed 30 years. She uses a walker most of the time now but this has only been in the last few years.

[@AHSCT-RUSSIA]

This phrase should not be taken out of context. It is not independent, but it continues the idea of the main theses of the film. And in this case, it will be correct to discuss the meaning of the film as a whole. However, as we have noticed, this issue has been raised repeatedly, so we will clarify our logic. EDSS is used to assess the course of MS in a patient. This index reflects the degree of disability of the patient. The progression (fast or slow) of MS is characterized by an aggravation of the degree of disability, the value of which reflects the EDSS. Therefore, the beginning of the period when the patient will not be able to do without a wheelchair depends on the rate of MS progression, on the age of the patient, and other comorbidities. The MS insidiousness lies in the fact that the patient does not die from MS, but from the consequences caused by the degree of his disability. And there's no doubt, there are patients who successfully fight MS and do not have to resort to a wheelchair. These are those patients for whom the issue of choice of the treatment type has already been resolved and they do not feel the need to change the method. In our film, we talk about the one of the existing methods, which is intended to stop the progression of MS in those cases, where therapy used is not effective enough.

[@ivonna.tinkle]

Everyone's experience is different, your comment is all anecdotal, and not that useful. If DMT meds works for you then great, for me it was terrible. I know that being wheelchair bound is a VERY real possibility so in 2018 I had HSCT in Russia with Doctor F. My last MRI shows that I have not any new or active lesions, it looks like HSCT halted the progression of MS, at this time DMT meds don't halt the progression of MS.

[@dimitrabardemi210]

Hey i a many years with this disease.I had flare up and now my walking its not the same.I don't need to think you could be worse i know that i want to be well .

[@brendakerber7923]

@@ivonna.tinkle I'm so glad that this worked for you. DMT's do stop the progression, not necessarily permanently but many for a long time. I know people who've done DMT;s who've not had progression for more than 5 years - that's significant. For me, so far, just one year but the drug that I'm on has only been available for four years -there are certainly people who've had no progression for that long.

[@brendakerber7923]

@@AHSCT-RUSSIA thanks for the explanation. You should change your language though. It's pretty hard to take the phrase MS inevitably brings the patient into a wheelchair out of context. That's pretty clear. It's also ableist to say 'resort to a wheelchair' - if you need a wheelchair, use one, they are great tools that make people's lives better. I just got a walk and wow! the difference in my fatigue! I will only be using it under certain circumstances but under those circumstances it will make my life so much better!

[@joannqzae]

ممكن واتساب المستشفى

[@AHSCT-RUSSIA]

The fastest way to get an answer to your question is to use the feedback form on the site hsct-russia.com/

[@عارفاللهيبي-ذ8ح]

عندك رقمهم

[@danyalrao-dl8lt]

Is this useful for ALS patient?

[@AHSCT-RUSSIA]

Unfortunately this treatment is not suitable for ALS -- Sincerely Yours, Denis A. Fedorenko MD, PhD, The A.A. Maximov Department of Hematology and Cellular Therapy, National Medical Surgical Center named after N.I.Pirogov E-mail: [e-mail]

[@mientay8255]

@@AHSCT-RUSSIAcan you treat for ALS please 😢😢😢😢

[@petvuk]

HSCT still induces early menopause by shortening the period for menopause onset for about 10 years for women. that is still very drastic. This sometimes decreases the quality of life and life expectancy for women. I hope these HSCT protocols will one day will be available without chemotherapy or at least much less toxicity. This is certainly a good start and close to the magic cure, but still no there yet

[@AHSCT-RUSSIA]

Modern lymphoablative protocol usually dose not cause early menopause. The risk is about 1% and mainly in people with premenopausal condition

[@petvuk]

How do you define early menopause? I understood it wont cause immediate menopause in most patients who are under 40, but as early menopause is considered < 45, it will cause most patients to reach menopause earlier by 5-10 years than they normally would, which will usually be before 45.

[@AHSCT-RUSSIA]

@@petvuk We have not received information about such cases, so we do not observe it at all. And it is impossible to unequivocally prove that menopause occurs precisely as a result of HSCT or chemotherapy.

[@petvuk]

@@AHSCT-RUSSIA well early menopause < 45 years old at onset is 5% of population so if it's much more in HSCT group, it's easy to link what caused it.

[@johnlefrancois8382]

Even if it were true that the treatments caused early menopause in all patients (which it's not), I'm sure they would still gladly accept that side-effect in exchange for the elimination of the suffering and guaranteed deterioration of MS. The treatments work! My friend now lives a life of joyful health without the life-destruction of MS.

[@عارفاللهيبي-ذ8ح]

رقم للتواصل

[@AHSCT-RUSSIA]

E-mail: [e-mail] HOW TO APPLY: Complete our questionnaire, describing your previous treatment and current functional status, to define whether HSCT is a meaningful and safe treatment option for you: hsct-russia.com/application-for-treatment Your medical records will be personally reviewed by MD, PhD, Dr. Denis Fedorenko.

[@عارفاللهيبي-ذ8ح]

​@@AHSCT-RUSSIAFrom the Kingdom of Saudi Arabia, thank you very much