Illuminating the secret world of your glycans

Did you know that all the cells in your body are covered with a thick and complex coat of glycans? These glycans, also called complex carbohydrates, play a vital role in keeping you healthy, but are also involved in most major diseases that affect mankind. Exactly how is still shrouded in mystery, but this video provides a glimpse into the secret world of glycans and the cutting-edge glycoscience research being conducted to understand their role in health & disease and to develop the therapeutics and vaccines of the future!
The glycoscience research is an example of Science for Life, one of the four themes within Utrecht University’s interdisciplinary research programme Life Sciences.
Dutch and English subtitles are available for this video.
This video about glycoscience research was produced for the Chemical Biology and Drug Discovery Department and was made possible with financial support by Utrecht University.
CBDD Department Website: www.uu.nl/cbdd
UIPS Website: www.uu.nl/scie...
Bijvoet Website: www.uu.nl/scie...
Produced by Sensu: sensu.org/

[@gabrielbarry7935]

It always amazes me how what we require for human health exists in the natural world and as our understanding of Biology progresses, we discover more and more ways to enjoy optimal health.

[@jenroberts7267]

Why would someone dislike this video? I'm currently in my 3rd year of study for my Bachelor of Science - one of my courses right now is cell biology - and I find this fascinating and promising!

[@xuedoucet447]

It's normal, our company produces these products that are so excellent and are proven to be very very effective by so many testimonies, there are still many who don't believe. Can you imagine this video is just science many people are lack of knowledge to understand this?

[@tinylangeveld5311]

ik ben zo blij dat dit op mijn pad is gekomen, mijn energie en vitaliteit is 360° gedraaid

[@0boarder0]

particle models of biomolecules are the most amazing thing to me

[@232Boundary]

We've been working with a company that produces the highest grade glycans in the world ...and can prove it. We've been taking these glycans and sharing with others for 16 years.

[@xuedoucet447]

My dad has been using these products for a year, his Hepatitis B virus has disappeared!:)

[@ZMacZ]

Are glycans like cell wall itself or are they just covering the membrane ? And would these glycans then be mixed in by things like hACE2 ? Or is hACE2 a glycan itself ? Or is it produced by glycans ?

[@ZMacZ]

After reading up a little, I'd say the following: "Introducing immunogenicity to the cancer cells, changing their outward glycans so their structures appear like something the T-cell should attack, rather than ignore, should cure cancer", while, "introducing tolerogenicity into the T-cells, changing their outward glycans so their structures ignore healthy cells of the human body, rather then perceiving them as something to attack, should cure autoimmunity." In opposition to: "Introducing change into the T-cells, to attack cancer" and "Introducing change healthy human cells, to prevent attack by T-cells." In both cases the change would be minimal, while the opposing yields much greater change throughout the entire body, especially the last one, in which you'd adapt the whole of the human cells. But also, can glycans and their study be used to combat Sars-Cov-2, by showing infected cells a different glycan structure on their surface, subject to immunogenicity ?

[@ZMacZ]

Also, the fact that there may be a way to indicate a cell for removal by chemical stimulus, rather than antibody signalling or such, would disallow even the smallest incursion by the SC2 particle, since the chemical stimulus to indicate removal would instantly allow removal by T-cell interaction upon succesful penetration by the SC2 units, rather than waiting for antibody signalling or such. I am very interested in this science's outcome in the fight against SC2.

[@ZMacZ]

The ability to keep a hijacked human cell from shedding additional SC2 units and near exponentially aggragate an existing infection is, like WOW. That would be like...WOW. I wish you much success.

[@xuedoucet447]

Our company has products made of glycans.

[@mannaman]

Too bad they had to throw in evolution. Such a ridiculous theory that anyone with an ounce of common sense can see thru. Foolish to think that design of such a complex nature could have simply evolved with no intelligent designer.

[@joejunior2786]

What an incredibly inappropriate comment to a really excellent video. Religious fanaticism seizing on one word to further an agenda that has no basis in reality. As a scientist, I like evidence; at this time, an evolutionary theory of our progress through time is what the facts suggest. Can that change in the future? Certainly. And as a scientist (and a human being) will accept that. If creationism and that an all powerful God created the universe in 6 days by waving his hand can be proved, I will accept that too. Right now evolution is by far the most reasonable option. But unreasonable people cannot even consider that, and that is the danger of organized religion. I would ask Mr. Phelps to live the old adage that "the mind is like a parachute, it only works when its open".

[@yazar8]

Life with such complex nature has no problem to evolve on its own due to the physical laws and self-replicating molecules being able to store and use information in several levels allows the basic formation of life, as long as the creature can seperate itself from the outer environment (extracelullar part) via a membrane. When this happens, self-replicating organisms can easily start making machines, given that enough time (billions of years) is provided. The whole process is dictated by physical laws. The real question here is, who has set these laws? It could indeed be an intelligent designer or it may not be.

[@gabrielbarry7935]

What if an Intelligent Designer uses evolution to produce the natural world?