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Iron deficiency can cause weight gain due to lower metabolic rate and overall lethargy leading to less physical activity but so can giving bolus iron via iron infusions.
Free iron is highly oxidative. And when you receive an iron infusion you are not getting iron bound to protein like transferrin or ferritin. You are getting a supraphysiologic amount of a highly reactive mineral put directly into your blood.
Oxidative stress, DNA damage, mitochondrial damage are hallmarks of obesity just as getting an iron infusion promotes these same effects.
This is why we want to reserve iron infusions for the worst cases of iron deficiency where no other methods are working or in emergency situations where the benefit far outweighs the risk to the patient.
A consistent steady rise in iron is what we want to aim for. This way you can experience all of the benefits of restored iron levels without the negative DNA damage.
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