Is A Ketogenic Diet Enough To Treat Cancer?

Dr. Tomas Duraj, physician and scientist working in the Seyfried Lab, discusses the nuances of the Ketogenic Metabolic Therapy.
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[@willbrink]

If cancer is a metabolic disease that happens related to dis-regulation of mitochondrial ATP production that become anaerobic, I wonder what benefit red light therapy might add to the overall treatment plan? It's interesting to note that people that live in sunny areas experience less cancers but for skin cancer of course. Specific wave lengths of light penetrate deeply and (supposedly) improve mitochondrial function. Dr. Roger Seheult at MedCram has done extensive discussion on that topic. You can find his YT channel easily.

[@Jack-2day]

For a deeper dive into ATP production via red light therapy I'd recommend Dr.Casey Peavler here on YT also

[@felixmartel1847]

very good point

[@BOZ_11]

sounds like an advert for D3 tablets

[@TheSpearoHeroes]

@@BOZ_11 Red Light therapy doesn’t make D3, that would be UVB light. Red light and Near Infra red light does stimulate melatonin production among other things. Melatonin has many anti-cancer properties.

[@BOZ_11]

@ D3 also has anti cancer properties (if you megadose)

[@NozaOz]

For anyone who is starving for information about metabolic therapy I highly recommend the KZbin channel by Dr Casey Peavler, incredibly thorough explanation of glutamine, glucose inhibitors and other kinds of strategies

[@jaghad]

Well, he's a doctor. He is not a researcher. He definitely hasn't studied statistics, which is a must to interpret research results. I haven't listened to him, but I have no time to listen to doctors on how to eat.

[@pboin]

Peavler puts everything out at an hour plus. Who has the time budget for that when there is so much else to read, listen to, and do?

[@fatimabonte-go3vy]

You right I also follow him he is very good

[@SamShank175]

​@@jaghadyou seem to know a lot about someone that you haven't looked up or listened to.

[@ngana8755]

Dr. Casey Peavier did an interview with Dr. Seyfried a few months ago with the title" EGCG DESTROYS Warburg Metabolism & BLOCKS Glutamine."

[@egg399.]

Thank you for your work, both!

[@dennisclapp7527]

Very convincing approach

[@debbiewebber1582]

I have metastatic breast cancer, and I have been eating a carnivore diet for approximately 16 months. My cancer is not advancing, like it used to. I eat less than 10 carbs a day, and that mostly comes from dairy. I've lost 100# and feel great. What else can I do to make it "go away"?

[@elenahingle699]

DON therapy. He uses low glucose, low glutamine. Glucose is lowered through diet, glutamine through Don. You will need a functional doctor to coordinate. There is an organization called Hippocrates research foundation ( something like that) that follows this protocol..at no cost to patient.. but can’t take everyone.

[@elenahingle699]

DON therapy. He uses low glucose, low glutamine. Glucose is lowered through diet, glutamine through Don. You will need a functional doctor to coordinate. There is an organization called Hippocrates research foundation ( something like that) that follows this protocol..at no cost to patient.. but can’t take everyone.

[@dalehallett8449]

Google search "Dr. Burt Berkson and low-dose naltrexone for cancer" Good luck.

[@inverted_real_it_y]

Fasting; daily intermittent and once in a while a prolonged (water or dry) fasts for a major clean-up.

[@ciuffoarancione8929]

Training lifting weights, walking at sun, ozonotherapy..

[@atfgga]

I have diagnosis of metastatic breast cancer since fall of 2023. I found Dr. Seyfried a week ago and have been listening to many videos etc. Can you please tell me how I can find a caregiver willing to participate in metabolic therapy?

[@egg399.]

where are you based? Search for Integrative oncologist for someone local to you!

[@naseemahallyson5003]

Email your questions to Professor Seyfried .. he does reply in a day or two .. prayers from Johannesburg South Africa 🇿🇦

[@laurapoirier741]

​@@naseemahallyson5003what email do we send questions to?

[@Stamnessj]

There is so much info on a therapeutic ketogenic diet online, even just on KZbin alone. Not saying that you shouldn't seek guidance from a healthcare provider, but rest assured that it is more than possible to do it on your own if you meet pushback.

[@lisaellsmore]

@atfgga Check out Howlett Integrative Cancer Care. Kristie helped me 😊

[@phebedunkelbunt9577]

Sorry, did not understand what you use to interrupt the glucose/glutamine metabolism?

[@ec6992]

Have been dairy-free grain-free keto for months. In addition to chemo, doing vit C and mistletoe IVs plus other drugs. Iver did nothing and Fenben caused sharp liver pain. Peritoneal tumors keep growing. 😩

[@chexterkat]

Stop eating meat.

[@eliasvonbernstorff6762]

try looking at dr casey peavler

[@santinasanchez1496]

Keep going. You're amazing!! Do you meditate or calm your mind from stress and stressful things, news, people and environments? As important as the physical diet and lifestyle when we're trying to heal fully. Best wishes and blessings ❤

[@ngana8755]

Question: Does substituting glucose with sweeteners such as xylitol or allulose help with cancer treatment? I'm wondering if a cancer patient with a sweet tooth can drop sugar and replace it with xylitol or allulose. Do cancer cells metabolize xylitol and allulose?

[@santinasanchez1496]

I've read the plant Stevia in natural powder form can be used as a natural sweetener and it doesn't affect glucose levels. Maybe you can read more on that? Best wishes

[@ngana8755]

@@santinasanchez1496 You've read? If you have nothing scientifically informative to say, please do not say anything. I was asking my question specifically of Dr. Tomas Duraj, physician, or Prof Seyfried about ketosis and cancer cell metabolism of substitutes to sugar.

[@santinasanchez1496]

@ngana8755 being rude and ignorant won't get you anywhere in life. Do YOUR OWN RESEARCH MISTER instead being lazy and expecting knowledge to be served immediately.

[@brettforbes]

Thanks Professor, if the key issue is to be calorie deficient, low glucose, high ketosis, how can we find diet advice on how to achieve this. Can you advise please? Also can you researchers please put forward a diet so we can adopt them, thanks

[@thomassaddul]

Eat low carb, eat mostly fatty red meat, IF 18:6, resistance training, take Fenben or IVER

[@fourshore502]

you can at the very least do short fasting every day. meaning, 15-16 hours of not eating every day. meaning: no late snacks, and late breakfast (or more like skipping breakfast altogether).

[@eliasvonbernstorff6762]

@@thomassaddul Why red meat? Does pig work?

[@thomassaddul]

@eliasvonbernstorff6762 Ruminant meat is best

[@enriquehernandez8993]

Miriam Kalamians' book Keto for Cancer.

[@fatimabonte-go3vy]

Thank you doctor

[@jeffg4686]

strict keto + curcumin + berberine - pretty good combo

[@hermanreulens2767]

thank you

[@btudrus]

OK, so how could ketones be "elevated" but glucose be high? Either these animals are still fed some carbohydrates (or even just fructose?) or something else must be done wrong...

[@clarencewoodbine6266]

agreed

[@nooks12]

Exogenous ketones?

[@JimBillyRayBob]

excess calories

[@MrGooch2706]

I believe the body breaks down the fat in meat into glycerol and fatty acids. The liver then converts the fatty acids into glucose.

[@btudrus]

@@JimBillyRayBob " excess calories " Ketosis normalizes appetite. There is no natural way to be in ketosis and eat excess "calories". Something wrong must be with the kind of food these rodents are fed with...

[@michaelgalvin1024]

Hyper or hypo thermia as systemic therapy?

[@skipperrick]

Sounds like a great five way ANOVA! Right, need an experimental design. Press!!!

[@eliasvonbernstorff6762]

Is he saying it is not possible to lower glucose (on keto) if eating caloric surplus? And therefore caloric surplus doesn't work?

[@ianwilliams1789]

That's how I understand it.

[@btudrus]

That doesn't add up. Ketogenic diet leads to the normalization of lepin signalling.If these rodents are overeating something is fundamentally wrong with their diet. Personally, I don't believe "calories" are the cause here but a symptom os something being wrong with that diet. Usually higher glucose levels will lead to higher insulin levels which will shut down ketogenesis. On the other hand, high ketones leves will shut down gluconeogenesis. That both, ketones and glucose are high - reportedly in this case - shows that something is going really wrong here...

[@Kiihhu2]

No, he's not saying that. It's just that it has been shown that calorie restriction provides added benefit to starving the cancer cells, in addition to pushing the glucose level down with ketogenic diet, I remember Seyfried talking about this. So calorie restricted keto seems to work even better than normal keto in fighting cancer.

[@laurapoirier741]

No, it's not possible for your glucose to go up on ketogenic diet unless your protein is too excess and turning into glucose

[@uncletony6210]

I have no Ifuckindea.

[@cyphercracker]

I use to follow a guy here on KZbin that was fasting 4 days then eating keto 3 days for 2years. They gave him 2-3 months to live but he made it 2+ years with cell treatment…. A bit ambivalent when it comes to keto starves cancer talk

[@djanitatiana]

Keto is only half the story. Glutamine needs to be addressed as well.

[@O0oFeelTheHateo0O]

@@djanitatiana Sorry, but any hint on how to do that?

[@djanitatiana]

@@O0oFeelTheHateo0O How to suppress glutaminolysis in cancer cells during metabolic therapy, specifically? Prof Seyfried details mechanisms in his latest press/pulse protocol, released late last year using DON (6-diazo-5-oxo-L-norleucine) which is not yet approved. However other glutamine antagonists have also been put forward, search "Glutaminase (GLS) Inihibitors that are stronger than DON?" on Dr Casey Peavler's channel for a discussion of those.

[@TheSpearoHeroes]

Great explanation!

[@cyphercracker]

For you smart people out there understanding what he’s saying: A calorie/carb deficit ketogenic diet?

[@LauraB.335]

He’s saying you want to be in ketosis on a therapeutic level, not just on the level where you’re able to lose weight or reverse insulin resistance. You want glucose to stay low and you want there to be a therapeutic level of ketosis, so you want the GKI as low as possible (therapeutic GKI is considered 3 or under). You also want to shift from sugar burner to fat burner and stay a fat burner consistently, as it is more effective.

[@douglascutler1037]

Keto is just stage 1. Stage 2 is blocking alternate cancer fuel source glutamine at the cellular level. That is the tricky part. The main drugs Dr. Seyfired proposes for stage 2 are currently only available in a research setting. More easily available means of inhibiting glutamine uptake are being investigated by others.

[@cyphercracker]

@@LauraB.335thank you so much

[@cyphercracker]

@@douglascutler1037I appreciate your response

[@cyphercracker]

@@douglascutler1037thanks. appreciate the response

[@scarter176]

It’s all about the money

[@cedriccottage2070]

I'm utilising sport after every non-keto meal and and once a day even on keto days after last (2nd) meal of the day. This helps me miracles with keeping my glucose in very healthy levels almost all the time. Has this approach been investigated?

[@eliasvonbernstorff6762]

What sport are you doing? How much does it decrease your blood glucose number? thank you

[@cedriccottage2070]

@@eliasvonbernstorff6762 Any sport you enjoy and can do for hours, or even switch throughout the time. Ideally something including legs as that is the fastest way of decreasing glucose. I do fast-waking, hiking, road & mountain biking, swimming, badminton, dancing, stretching fast-pace yoga style, dance workouts, or if on business trips and nothing else is available, fast-walking emergency staircases up and down over and over again. Glucose drops within minutes to below 100 and after 20min settles in the 80-85 levels. This even when I used to start with 160 - 180ish spike. And I no longer have these spikes at all, likely due to the regular workouts. Hope this helps!

[@scarter176]

Why don’t you make DON available ?

[@evgeniakotsifos7878]

It is available online

[@Wuifgong]

It is not something you should take without a medical professional.

[@dadaradabada6928]

@@evgeniakotsifos7878 its not.

[@prelovedbargainsandantique2245]

So, eat high fat, low protein for it

[@btudrus]

That is apparently NOT what is going here. If these rodents were fed too much protein and too little fat, not only would their glucose be high BUT also their ketones be low. WHICH IS NOT THE CASE!

[@douglascutler1037]

@@btudrus Rodents in the study received Dr. Seyfried's press/pulse therapy and according to the claim it triggered dramatic remissions of gliobastoma brain cancer. Press/pulse is 'press' or restrict glucose with steady state ketosis and 'pulse' glutamine with intermittent use of special glutamine blocking drugs. Blocking glutamine can only be done at the cellular level because the body makes it's own glutamine from other nutrients.

[@scarter176]

The next frontier ? BUllshit !

[@scarter176]

Why do doctors keep pushing standard of care knowing all the time it does not work ! When will you stop this nonsense ?

[@edwardcdg]

Because they will have their license pulled if they speak against it.

[@edwardcdg]

KZbin will also sanction them

[@douglascutler1037]

@@edwardcdg Correct. Doctors fear repercussion from their respective medical boards if they recommend something outside standard of care. What if they recommend something new and somehow it does not go well? Everyone fears legal repercussions. They won't discuss it even if you bring it up and will claim ignorance or worse. Doctors get so used to working within standard of care restrictions it becomes too easy for them to dismiss and disparage new therapeutic models even if the new therapies have good clinical evidence.

[@booneland1297]

Chemo… (standard of care) Noooo way!

[@enriquehernandez8993]

It works for some and for some, it does not.

[@AugustinAugustin-n1y]

Ketogenic OK , but you can't stop glutamine in your body, cancer likes glutamine too ,so what happens now ,the cat bites in her own tail????

[@fourshore502]

yes you can stop glutamine with the DON.

[@PeterPan30000]

@@fourshore502 DON?

[@dmarcellus]

@@fourshore502 DON?

[@wdahoi3153]

DON treatment is his magic treatment for that

[@ericschnittker6775]

THUMBS DOWN. He speaks TOO FAST, hard to understand him. Not speaking to the average person, more to other scientists. This video is useless to me.

[@wanton7306]

You can slowdown and speedup videos in KZbin.

[@AshishSingh-qq5rv]

Oh you'll understand if you're personally affected by this disease

[@Anne-LiseH]

Turn on subtitles. His speed is pretty normal though.

[@Navs126]

It’s not useless. You’re just too dense and just to add injury to insult you’re also close minded. Relax a bit, be a little less sensitive and hardheaded. Settings on the top right will allow you to slow the video down 😉

[@ericschnittker6775]

@@wanton7306 Yes, that helps a lot, thank you.