Hidden Item Effects You Didn't Know About #6 - The Binding of Isaac Repentance

In this video I'm going to showcase some less-known or hidden item effects that some people may not know about. The goal is to raise awareness about new item effects introduced in Repentance and to teach newer players about some older ones.
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#thebindingofisaac #tboi #repentance

[@lazysheetghost]

an interesting sort of thing I remember about sanguine bond is that the spikes are also in krampus' room and can hit flying enemies just like the sac room spikes, the result is krampus' getting bent because they share the same spawn tile

[@The_Dev_175]

I love the use of “getting bent” instead of getting hurt SO much.

[@doctorhealsgood5456]

I wonder if you can use krampus as payment

[@adame.9469]

@@doctorhealsgood5456 *i will pay my taxes with my krampus*

[@ShaboingboingBouncer]

@@adame.9469 *krampus can be exchanged for goods and services*

[@goldensycamore2097]

Idk if this has been already stated but if you play Tainted Lazarus on any floor with reflective ground, you can see the other version of yourself in the reflection.

[@shawermus]

Btw is it working with birthright?

[@goldensycamore2097]

@@shawermus I don’t know how birthright would affect the reflection. It would probably have tainted Lazarus’s dead and alive version have their own individual reflections. Or maybe not because the other version appears as a ghost? I would have to test it out at some point to see for myself.

[@specterx2135]

I love how the brimstones from locust of war were actually smaller, even having a different sound, just like how it usually behaves (the small explosion sound effect)

[@MsChi-bc8tw]

In similar fashion with "we need to go deeper", holding "the red key" or "red key piece" can help you find more easily secret rooms as they show where you can open a red room.

[@matteograziosi8203]

Death's List is guaranteed to pay out in trap rooms, since there are no enemies to kill.

[@terramarc]

Tron pocket is such a weird throwaway joke to put at the end of the video and I love it

[@geoluread3436]

I know I'm late, but the synergy between flush and death's list might be for a different reason. a similar thing happens if you have death's list and some freezing effect like ice cube, where an enemy is not counted as "killed" if it is frozen instead. If you freeze an untargeted enemy, the skull will still remain. I think enemies getting flushed or turning into poop isn't considered the same as normally killing them, so the game just thinks you did it in the right order because it didn't see you kill anything in the *wrong* order

[@EgorCharonov]

Interesting fact: If you don't open all the chests in the Dark Room as Lost/T. Lost, they won't disappear after purchasing an item (Add this fact in video plz :3 )

[@Heometric]

This isn’t an item fact, but if you only have one heart container, health downs become health ups. (I saw 3 health downs in a room, I decided to end the run but when I had one container left, it gave me a health up) This might just be my mind but, try it out!

[@demianhernandez4889]

4:54 haha it sounds like popcorns

[@drajp6987]

i know it's not an item effect but it's fun cathedral and sheol have always the same layout in a run

[@Evenvagolor]

Found out if you have match stick in your trinket slot and pick match book it doesn’t drop it

[@garciarodrigueznicolas7295]

A fact: if you use mom's bracelet on your own bombs you can throw them as if they were red

[@paavofritschi1327]

Quick questin when will be the 1.75 patch release on switch

[@argong1]

not really an item effect but if you pick up greed's gullet while having 12 soul hearts and like pick up coins and stuff you'll have more than 12 hearts

[@laval0910]

4:50 i was trying to unlock forgoten and got fucked over because i cleared boss rush and the other item spawned on top of me and the shovel piece dissapeared.

[@milodiin]

3:42 When an item is so unused it's main effect is considered "hidden"

[@Ryusuta]

See also: Torn... err... "Tron" Pocket. XD

[@TheGiantBreadbug]

same at 4:04 , THATS THE ENTIRE POINT OF NUMBER MAGNET

[@schizopenguin]

​@@TheGiantBreadbugi mean its also kinda like voodoo head for devils and by the time you find it youll have probably fought krampus sooo

[@SlayXc2]

Thanks for the shout-out ^^' I was really excited when I discovered the Delirium instant-kill :D

[@kingping3555]

Damn I just got a crazy idea. Imagine if while wearing either Spelunker hat or Host hat and getting Damocles'd you were left at half a heart and the item protecting you disappeared along with Damocles. Would be a cool mechanic

[@mystrrrreioucuszthlpepperac]

Or Damocles appears skewered into your skull and it grants a 50% to duplicate an item

[@superwhatevergamin9634]

@@mystrrrreioucuszthlpepperac Isaac: My head hurts. You guys, my head hurts! T. Azazel: Bro, that looks painful- and I had my wings amputated.

[@Samuel-jn2oc]

Or you change character into glare

[@Winasaurus]

Conehead isaac should just have his cone bonked and lose both conehead and damocles and be left with little health.

[@Samuel-jn2oc]

@@Winasaurus or he becomes gregg the egg

[@lydia8226]

I adore the super specific triple item synergy. I want more stuff like that in the game

[@shanedancer3895]

My guess would be it was planned for the glitch chests to actually be able to spawn and be openable but they decided not to do that but just reused them for the broken motem effect and didn’t realize it was possible to actually open them lol

[@shweedy_]

@@shanedancer3895 if that were true they would have used the milk for the items

[@mehmetkursatyasar54]

if you turn into lost by touching white fire place and take “lost soul” item, the lost familiar will gain holy mantle for the rest of the run.

[@sunbleachedangel]

About that last one, invincibility frames in this game are directly correlated to how much damage you take, so if you take 2 damage from the BIG champion, you also get double invincibility frames

[@beanslinger2]

i thought that was changed when repentance came out

[@XenusYard]

@@beanslinger2 Nope

[@sunbleachedangel]

@@beanslinger2 I think it was only holy mantle

[@ChillstoneBlakeBlast]

This is true until Chapter 4, where Every source of damage becomes Full heart damage. The Invincibility frame rule still applies though, So if you are in a situation where you can take a regular or Champion hit, Taking the Champion hit is grants more I frames.

[@kakashilover9231]

I always love these vids as it gives me more insight on the game. I can't test this out myself as I'm console so no commands

[@syffdvst]

Hey but does anyone know when is console getting another update?? bc i didnt got an update in ages and we are still missing some items that are in pc like glass eye

[@kakashilover9231]

@@syffdvst yeah and our tainted characters still use their old mechanics not including T Cain

[@syffdvst]

@@kakashilover9231 YEA BRO LIKE- I FUCKING HATE THAT- edmund pls update tboi on ps4 im dying inside-

[@kakashilover9231]

@@syffdvst worst part is I get so used to watching others play an updated version that I think [instert item] does this but really it doesn't because PS4 has an earlier version fsfr

[@syffdvst]

@@kakashilover9231 you're so right lmao

[@giovannimorelli4592]

The Tainted Lazarus bug with Bone Spurs also applies with the Boney and orbitals from Book Of The Dead, giving you an army of Boneys

[@benito6036]

I just was wondering how my Tainted Laz run had so many Bonies! Thanks

[@sethcommitstaxfraud8365]

this happened on the first tainted laz run i ever did, was able to bring delirium to about half health with jus an army of boneys

[@giovannimorelli4592]

@@benito6036 no problem

[@Ethan-xo1yc]

If you use keepers box in a boss room after using satanic bible, it'll cost soul harts for items or have spikes around consumables, this even works retroactively if you use the satanic bible after and reenter the room

[@soyfiish]

It's not an IsaacGuru video without fatty slaughter. Anyways, these are actually pretty cool, especially the found soul, and I think anything that gives soul hearts directly might work, but I am not sure

[@IsaacGuru]

I tested many items but only Dream Catcher seems to work.

[@Zabe_B]

@@IsaacGuru did you check if dream catcher also gives soul hearts to co op players? that may be the key

[@skorpionex87]

Crow Heart trinket prevents from losing bone heart containers as long as it still has red health (OP with Forgotten).

[@elle3562]

Huh, that's one of those things that seems obvious in hindsight, but that I doubt I ever would have considered on my own. I'll have to keep that in mind, thanks!

[@krakis51]

Did it means I lost my run of Forgotten because of this ? Probably, good to know haha

[@blomtomb7103]

Actually, for the ipecac one, it’s ALL damage that deals a full heart which gives you longer invincibility frames, not just ipecac !

[@burn1none]

hey I found a neat interaction to break the game the other day if you use Keeper's Box to spawn a shop item and have Restock it will generate a new item when you buy one from the shop but the price doesn't increase. You have to buy a key or heart or whatever spawns first but then it turns into a pedestal item. I had a Steam Sale so I was able to continuously generate money, buy items for 7 cents, buy Chaos, then break the game. Makes the Keeper's Box much better imo. I think using the restock machine made the generated items disappear but I was already broken at that point so I didn't do too much testing.

[@mangoes443]

Tainted Jacob can survive another hit in his lost form if he has an eternal heart. (Will not work if he has soul hearts) (Does work if he has only half a soul heart without any other containers)

[@yoshmeme931]

Found a cool one in a run I had the other day. You need both Hemoptysis (tainted Azazel's sneeze item) and the Best Friend active item. When you put the Best Friend down and hit it with the Sneeze it will become magnetized to enemies for some reason. It works really well on early game bosses. I don't know if its a bug or intended, but it was cool to find for sure

[@pydim]

Isaac spawns flame when he farts and has an item 'Bird's eye' or 'Ghost peper'. Hovever he also does that when mucormycosis (spore shot) procs (farts). This synergy usually leads to a room filled with flame

[@rood1047]

Hidden item effects: "Sissy Longlegs" can charm enemies when she touch them "Lil' Dump" make synergy with "Ghost pepper" or "Bird's Eye" , spawns flames when he farts "Luna" tears bonus persist in the Knife part 2 puzzle

[@greggodeggo436]

3:14 The first time i used blank card on my first file i had the double active card on me so this happened, i was so confused that i thought that teleporting to the error room and then disppering was what blank card did, so i never used it until like 3 months later when i realised what it actually does.

[@mystrrrreioucuszthlpepperac]

Not an item, but in Downpour II, the soul of cain [if used in the same room as the mirror] demolishes the mirror

[@dungeaterfancam]

I think it’s cause of the way opening doors with items works in the game, you don’t actually open doors in an uncleared room or leading to the to secret room, you literally destroy them with bombs or some item, and all other doors need some other item to open and when you offer that item they actually open by themselves after you insert it. But the mirror doesn’t use an item to open, it needs you to use the white fireplace and already has free access for Lost, Forgotten, their tainted versions and kinda T Jacob. So the soul of Cain just uses the only item interaction the door has, which is a bomb.

[@mortaxtheduck7994]

@@dungeaterfancam I didn't know The Forgotten could go inside of the mirror for free

[@dungeaterfancam]

@@mortaxtheduck7994 his soul form can, yes

[@okey7281]

not sure if this was mentioned already, but heartbreak can essentially give “lost” characters extra HP since it will protect them from lethal damage. works especially well on t. jacob. cool video!

[@rompevuevitos222]

Already covered in a previous video

[@kapustinek525]

I feel sorry for pointing out that he said “tron pocket” last time and now he made the trinket name into “Tron pocket” and the description saying “You misspelled it!”.

[@epiclotad]

I experienced a glitch with Tainted Lazarus when playing with my brother. We got Poké Go and a golden heart. Every time we flipped we got the coins from the Golden heart and a Vis would spawn (sometimes in groups of 5). The game kept crashing

[@sideburns2470]

10:34 isn't this because flushing enemies stops them from being killed, similar to the Uranus + Death's List combo? Knowing this, Ecoli could potentially pull off the same stunt. Similarly, Berserk + Uranus is a terrible combo, as Uranus's freezing effect prevents you from killing enemies to increase Berserk's timer. Lusty Blood + Uranus may also be a terrible combo for the same reasons, but I haven't encountered that in game.

[@dungeaterfancam]

Not sure about berserk but I’m fairly certain lusty blood still works with Uranus

[@DaveDoesDumbGaming]

5:29 this might be explained, since T.Laz flips between alive and dead he can possibly be dropping his bones, but thats extremely unlikely

[@mintymechanic8420]

Fun synergy: Knockout Drops + My Reflection = Hook Punches Can be combined with luck ups for more consistent punches, shot speed means faster punches, etc.

[@atomic5134]

Best bud, the fly familiar that appears when you take damage, does the most contact damage out of all familiars in the game, including sac dagger.

[@dungeaterfancam]

I hate the name of this item, literally the least cooperative familiar that comes out only after you get hurt (tied with dead bird and fat bird I guess) is called Best Bud, a guy named Intruder is more willing to help.

[@applesaregood]

The real Secret is that it's the second 5th video Lol good vid

[@IsaacGuru]

I knew I forgot something.

[@tiffanu]

I got that broken modem glitched item interaction totally by random a few weeks ago! I had no idea what triggered it thanks for the explanation!

[@xaulth5376]

Hello, i don't know if is intentional or a bug but when you use the Genesis item while you have flames from the Lemegeton item, they disappear but the items remain forever but don't show in the HUD.

[@syffdvst]

This happened to me and my friend, but we used the R instead. Pretty broken i guess

[@IsaacGuru]

Definitely a bug. The wisps will disappear if Lemegeton is used again. This also happens when you remove the wisps via the debug console, so it's definitely not intended.

[@LohStorm]

esau jr's familiar is actually more than twice as strong as abel (like if you were cain) and unlike abel cannot overlap itself

[@lucaraggio4614]

Terra + The Finger The Finger acquire Terra ability to break rocks, much faster (it's tick based) and wirelessy!

[@poldullo6998]

Night light remowe curse of the darkness

[@Malthinae]

Not sure how "hidden" it is, since most bomb items also work with Dr. Fetus, but I'm peculiarly fond of the Dr. Fetus + Rocket in a Jar combo for the ability to shoot actual rockets instead of bombs, removing most range penalties from the item. Great series, very informative =)

[@ChillstoneBlakeBlast]

11:10 That has always been the case sith Full heart Damage before The Womb

[@dima33]

1:42 русским привет

[@nonidog9515]

Me who plays with EID: Wow, that's the thing i knew my entire life

[@ryannakao7265]

Items that grant flight allows tainted forgotten to fly over pits Edit: 1.7.8 has updated and an unused boss has appeared

[@aperturescienceguy2737]

The glowing hour glass + more options combo also works with the alt path items

[@Whuim]

1:47 валерий львов русскими буквами

[@Hanzo-mainer]

Да, че за дичь

[@ATozz-1337]

The amount of time the creators invested in synergies with damn near countless hidden mechanics is what makes this game so replayable, fun, and mysterious. Thank you for the hardwork on your videos. I just got this game and I love these vids for learning more.

[@aperturescienceguy2737]

Boys we found the solution for the holy mantle nerf, make a mod where the losts spawn with blind rage gulped

[@homerosz97]

I have a good one. Using the Forget me now on an XL floor puts you back on the first stage of the chapter

[@uhbif7776]

Using Glowing Hour Glass immediately after using Alabaster Box will activate the effects of the Alabaster Box in the previous room while not consuming it. The reason for that is because Alabaster Box has some sort of "activation" delay and this "activation" delay will not get canceled by going back in time one room.

[@ooofboiz]

Fun fact: (this one isn't a game change or anything, it's a fun detail) when dark Esau charges at you, he will do less damage than when he gets inchsnied, this is probably because Esau has a burning hate towards Jacob so the chaining makes him angrier

[@CrowDoF]

2:56 Luck: 420.69 NICE

[@goosemchonk552]

Using "Book of the dead" as T.Laz creates so many bones, that it's impossible to actually get hit

[@pepelagarto8110]

1:29 fun fact: if you have the faded polaroid gulped it doesnt open the ascent door

[@hopotion5104]

Fruit cake has a lot more hidden effects, even the ones that do not correspond to actual items, e. g. some shots can turn enemies into poop, or teleport them in the random spot in the room, or the most broken one, it looks like it has a chance to spawn a rune on hit! Im not sure how exactly it works but I had a few runs with it where runes just started appearing out of nowhere, can you investigate that pls?

[@f.h.k6356]

I think they are wisp tear effects? It’s weird fruit cake has them but cool nonetheless

[@AleksandrNevskiyu]

I once had cake and kill many enemies with one shot and all of them dropped cards.

[@kingping3555]

Yep you're right. It can also spawn cards and coins. I remember a Hush fight where runes and soul stones just kept spawning and it was pretty op

[@flixr2576]

Idk If it fits Here but i Played tainted Jakob and Had an eternal Heart after getting Hit by Esau After that taking DMG doesnt kill but removes the eternal heart

[@spacer-lx5pq]

Works the same in the mirror world

[@robuxyyyyyyyyyy4708]

8:17 That is cursed

[@CupCuppington]

stop giving me car insurances ads i don’t know what insurance is

[@iamdingus]

Suplex damage scaling with size is almost certainly a reference to Seismic Toss from Pokémon

[@Idran]

I mean, couldn't it just be a reference to physics? That's why Seismic Toss was designed to work that way too after all :P

[@GodChaos333]

Ok. I always liked locust if war and Vade retro, but now I see they are even better then I thought

[@Ryusuta]

3:12 - Nice beatbox sound you got going there!

[@kwaczuh]

Hey if you spawn Red heart in Black super secret room you will get Black heart not red

[@SpikyBlade]

Same thing if you spawn a black heart in a red super secret room, it will give you a red heart instead, or at least it's what happened to me

[@kwaczuh]

@@SpikyBlade ye

[@marlonrojas1864]

Some days ago in a gamermaldito video he got sack head and a red chest gave a troll bomb and a sack with a consumables and the other troll bomb. But also I got a question, because in the same video he used diplopia with a queen of hearts and used both on the same room and both gave exactly 1 heart, what could be the reason or it was just random?

[@IsaacGuru]

Not sure what the first part of the comment has to do with the second but oh well. It was just super unluckiness. A doubled card doesn't mean it will produce the same effect.

[@marlonrojas1864]

@@IsaacGuru Nothing, the first is about the effect with sack head and the other is the card thing, both happened in the same video though. Wow, pretty bad luck haha. Tnx for the answer.

[@jeusWRLD]

Don't know if this counts or not, but I think there's a small chance each time you launch the game for the icon of the game to be Tainted isaac instead of normal Isaac. This has happened to me twice so far

[@MrNe0_]

Actually some items as Tainted Laz are literally just... broken. More specifically those that spawn temporary familiars like Book of the Dead, Book of Virtues or even Lemegeton. What I think the game wanted to happen is for the familiars to disappear when flipping and respawn for the Laz that spawned them, but the game never despawns them to begin with. So you just stack and stack these familiars until eventually you just have either an army of boneys or become a wisp beyblade. Imagine getting a damage wisp from Lemegeton and just duplicating it with this bug.

[@phnxsu]

using the poop while having hallowed ground spawns a holy poop without taking damage

[@tju960]

I believe invincibility frames are determined by the amount of damage you take in the game. For example, if you were to take 2 hearts of damage through that one enemy champion version that's double their average size (idk what they're called, so I'll call them Giga champions) you have a much more longer invincibility than if you were to take half a heart of damage, or a full heart of damage. Unless everyone already knew this lmao.

[@deoxysandmew2162]

Isaac Guru, Im not sure if this was mentioned before but here goes: "Found Soul Trinket comboes with Anima Sola and uses 2 chains as opposed to 1."

[@overmichal]

paszteśnik, jestem pewien ze to widz ryfka :D

[@witchamy]

longer s from 85 dmg ipecac is just how s work. if you take damage from a large champion (2 full hearts) you will have the lenght of s quadrupled

[@talinah7720]

Something I found in Greedier mode, if you have multiple copies of Guillotine, the damage and tears increases stack for each copy, and can even exceed the soft tears cap by itself - I found it our by using Guillotine with Box of Friends as Lilith

[@superwhatevergamin9634]

Esau Jr. grants flight. This effect of flying remains active in The Knife Mineshaft. Also it causes weird item trading effects if multiple characters use that jar.

[@der_Alptraum]

i have played this game hundreds of hours, never managed to get the complete Bandage Girl :/

[@Ngcdswii]

Maybe it's more known than I think but if you take a Bombs are key pill while having a golden key, it will turn into a golden bomb instead and viceversa.

[@0rangepel378]

It seems that, at its final level, if Blood Puppy charges into a boss, it can sort of attach to that boss and continuously deal damage to it. Edit: Note that it can happen with normal enemies too, it's just usually only noticeable on bosses because regular enemies die too fast.

[@2xw291]

Paszteśnik OMG XDDD congrats bro

[@fangamelocation6752]

Not a hidden item effect but funny thing. when you get hit by colorful enemy type (forgot name). immortality frames are longer.

[@Lichtkrieger13]

(Again, this is from an older version so IDK if it still works) 1. "Ace of" cards also turn friendly monsters into the respective pickups. Including monsters spawned by Friend Finder and the Pokeball 2. Ghost Bombs make your bombs have spectral properties - you can push them through stuff, not to mention that Dr Fetus takes advantage of it

[@keith9022]

You can destroy all Grimace, all Stone Shooters, Stone Eyes, Brimstone Heads, and all Stone Maws (or the indestructible stone things if you have no Idea what im saying) with the Little Horn item Edit: they can also destroy Slides, Pokies, Wall Huggers, and Grudges (the squares that has spikes)

[@kotymeow]

Prize bombs have chance to charm enemy in a room

[@superwhatevergamin9634]

The Emperor? card can spawn a boss fight with say Reap Creep and obsidian if used in a Dross floor.

[@reboot3332]

Not sure if this is a bug on the Switch version, but as T Laz if you use any item that gives you a familiar, it will double them up every time you flip meaning you can get an easy win pretty much every time. For example if you have Book of the Dead and get a bony, when you flip it will give you two bonie, then 4 then 8 etc. It also works with Friend Finder, soul of Apollyon and Book of Virtues. It was basically the only way I was able to get Boss Rush done in time as I could never be powerful or fast enough to make it to and through boss rush.

[@Tanuki_Destiny2107]

Wait…so if Flush adds downpour-like water to the room it is used in, does it make that room share the same synergy that jacob’s ladder has in the downpour/dross levels (more lighting chains and longer chain reach)?

[@jasan9973]

6:38 Maybe this also works with the rock-breaking tears from Sulfuric Acid.

[@IsaacGuru]

Nope. It's just Terra.

[@Lichtkrieger13]

If it wasn't patched out already bone spurs isn't the only bugged interaction with this, anything that can add a number of supporting entities can reappear and double when you flip (friend finder and jar of wisps are example I've encountered, that duplicate until their maximum). I'm playing on switch, so it might've been patched out with newer versions

[@zetamario8763]

It may only be the PlayStation version but Tainted Lazarus has another glitch involving golden hearts. If both have 1 golden heart and different amounts of health, every time you switch it acts like you broke the heart and money appears, without actually losing the golden heart. And I'm unsure if it's related but every time this happens it also doubled my spiders and flies.

[@Cheshire_Cat137]

Watched every video to make sure this hadn't been talked about yet. But with the item, Immaculate Heart, the orbiting tears are just far enough away from Isaac that he will not get damaged by them if they are Ipecac shots as the explosion is typically out of range. It's possible to get hurt by the explosion if you're moving a ton, but I've only seen it once or twice when I found it.

[@XenusYard]

4:53 for a fire beat 🔥🔥🔥

[@salmanagus8855]

I don't know if somebody has mentioned this. If you absorb the glowing hourglass using the void, you can get a free retry in every room since the void will be fully charged again But if you also absorb the lemegeton beforehand, you will also spawn the last wisp, and you can do this indefinitely since the void will always fully charged Probably a bug

[@Knever]

Just a clarification on the Ipecac damage regarding half heart/full heart damage and invincibility frames; The i-frames are based on how much damage you take, regardless of the source. A full heart of damage will always give more i-frames than a half heart.

[@vibinnugget9429]

The There's Options? Thing in the boss rush... I KNEW IT CUZ IT FCKED MY RUN TO UNLOCK THE FORGOTTEN!!!!! *ANGERY *