PRP Injection vs Stem Cell Therapy for Knee Arthritis

[@baronessvarney9379]

I am 68 years old and 4 years ago I had 2 torn miniscus and a bone spur in my left knee and med to advanced arthritis in both knees! The orthopeadic surgeon wanted to operate on my left knee snd give me steroid type whatever for my arthritis. I had stem cells from a delivered placenta (so no moral issue) and my own blood plasma spun and put into a shot for each knee. It worked fast and after 4 years, my knees STILL feel like new!

[@JeffreyPengMD]

Wow what a wonderful outcome! Thanks for sharing your experiences.

[@baronessvarney9379]

@@JeffreyPengMD You're welcome! It always surprises me that insurance won't cover it! My ins co won't have to pay a fortune for my knees in the future, you'd think they would see the economics of it if it works!

[@snakeshiet]

when you say it worked fast, how soon did you feel relief ?

[@baronessvarney9379]

@@snakeshiet Honestly, the next morning I was a lot better! But, I would say to get to really good and feeling cured, probably 4-6 weeks. But, I could tell right away it was good, they say the stem cells go after inflammation and the inflammation was miles better pretty fast. It cured the two torn miniscus too! The nurse told me that they have had people cured of a torn miniscus by using just their own spun blood plasma! I'm in NJ, not sure how the stem cell situation is in all the other states.

[@KevalShah8]

So you got a combined PRP and stem cell shot? If you don't mind me asking, how much did it cost?

[@claud1834]

I had PRP injections 13 months ago. Happy to say I’m pain free. I had arthritis in my hips and each hip received an injection. I also had a sprained ankle with torn ligaments/plantar fasciitis. Injections in my feet 9 months ago and I’m back hiking and running. This doctor explains PRP exactly like my problems. Important to know that the injections improve over time. I was disappointed after the first 2 weeks and then my doc reminded me that the relief from the injections would take 1 month. That’s exactly what happened. I’m sold on PRP! No drugs and it’s your own cells working!

[@davewotson7181]

Hi how much it cost you and where did you get it done from

[@davidlo168888]

You say lie. You don't know the culprit of osteoarthritis. If capillaries are clogged, PRP can do what???

[@ownyourdreamhomenow2800]

But how long do the results last? Is it permanent or just a few months?

[@Armurp01]

@@ownyourdreamhomenow2800 You treat it as if it's a Disease welcome to the Annual PRP Shots Club to control that Disease.

[@jzmouse8842]

My son had small knee surgery. Waited 2 weeks then I paid 850 for the PRP. His healing time wascut in half. He was back to 100% in sports by month 4.

[@femdog13]

Hey! I'm a Family Medicine doctor as well. A cousin of mine is looking at PRP vs stem cell injections and wants to know my advice. This video was awesome and right in line with my thinking and research on the matter. Also really appreciate how relatable and accessible you lay out the basic science and the research. Well done!

[@JeffreyPengMD]

Awesome, thanks! Keep up the great work!!

[@venatheus6101]

Ya i agree my left knee is my prob & stopping me from playing tennis & other life style activities his vidéo is clear ill start with prp 1st

[@AngelDenker]

Thank you so much for this. Just had my first PRP injection of the knee and so far, I felt relief within a week. Setting up my next appt.

[@paulendes]

He is very knowledgeable and helpful in me making decisions for my knees.

[@L1felock]

All I can say is thank you. This is the best education on this topic I've seen

[@JeffreyPengMD]

Glad it was helpful!

[@arokiyaraj1562]

​@@JeffreyPengMD doctor i have ACL partial tear and PCl buckling and pain over the cartilage

[@lindalee3729]

I had the PRP for a meniscus tear and wow it has done amazing ! Hoping I can eventually get one for each shoulder 😊

[@EPIUNF]

your video helped me greatly.. thank you for taking the time to concisely present this information. PRP has not worked for me.. i've had 3 injections of PRP and i am bone on bone.. essentially said i need a knee replacement when i'm 50.. haha ok i'll wait 13 years with pain.. but i was contemplating stem cell therapy and this certainly helped me make my decision.

[@susipangabean9343]

I am 62yrs old and had NStride APS injection (1 step higher than PRP) on one knee and it worked quite well on pain relief but the problem I was bow-legged on 1 leg and the bone-on-bone on medial compartment of my knee caused my leg to be unstable & give-way when walking so 10 months after the APS injection, I had a proximal fibular osteotomy to straighten my leg and arthroscopic meniscectomy to trim my torn meniscus. It has been 3 months now and I am happy with the result

[@JeffreyPengMD]

Thanks for sharing your experiences. Glad to hear you are happy with your outcomes, that's whats most important!

[@PhilipJBernardi]

😛

[@drhassanmubark7789]

The honest truth, a combination of mesenchymal stem cells (particularly expanded high number) and PRP is far superior to PRP and long-lasting, what stops people from going for the therapy is the cost and are not covered by the insurance companies, cells are the building blocks and plasma has numerous positive proteins and growth factors

[@petertulich7842]

How about shoulder joint arthritis? Any experience or ideas of what works best?

[@bhawanid9542]

Thank you for your review and information. This is the best channel for information on osteoarthritis. I am on PRP injections and they do an excellent job in managing arthritis.

[@JeffreyPengMD]

You are so welcome! I'm humbled by your comments.

[@LesliePenczek-x4x]

GREAT JOB !! 👍👍 in explaining everything ❤ I’ve learned more with THIS doctor than ALL 3 of the other ones I saw

[@drhassanmubark7789]

Excellent video Jeffrey, the stem cells combined with PRP for large joints give more prolonged and sustainable results. Small joints PRP does not work, so as you said it depends on the clinical case. Adult mesenchymal stem cells are safe but less potent than the pluripotent ones but the latter ones can carry a small risk of cancer-teratoma. I am confident all regenerative medicine products have a positive effect but PRP is the cheaper practical option. I have been doing expanded stem cells for 5 years and PRP for 10 years with good effect. I use one-off PRP but trying higher dose to reduce the costs of multiple unaffordable sessions

[@JeffreyPengMD]

Thanks for taking the time to comment! Too bad we can't use culture expanded cells here in the US.

[@batman-sr2px]

there is a lot about joints but what about muscle pathology? For those that had a previous history of large muscle tear that scarred and eventually healed but with poor result, is stem cell any effective and what type of stem cell treatment would help for muscle remodeling/regeneration? Also for these treatments, how many do you recommend if cost is usually an issue?

[@shaynadavidovhansonrealtor]

@@JeffreyPengMD Where can they? Thank you for the informative video!!!

[@GTSCoupe]

So why would anything other than pluri potent stem cells be in consideration or use?

[@batman-sr2px]

@@JeffreyPengMD I remember you responded to my comment. I can't find it anymore. Do you mind responding again.

[@billychrist21able]

PRP cost me over $1,000 and it didn't give me any relief. Stem Cell injections cost me $2,000 and gave me instant relief that lasted over 2 years. So I paid for another $2,000 to receive shots in my shoulders and back. Instant relief! It's worth it to pay more money and get relief rather than paying cheaper without results!

[@JeffreyPengMD]

Wow, that's pretty cheap for stem cells! The cost difference between PRP and stem cells are often 4-10x the cost. Which is why in many situations, PRP is more economical and a better starting point. If you find providers that can do stem cells for cheap, then yes, it might make sense!

[@suhaib23]

Where did you do Stem Cell Injections for $2k?

[@gaylandbarney2231]

@@suhaib23 i'm guessing Mexico .... also fat/bone marrow stem cells ARE NOT the way to go , from my understanding thus far , but cells from placental donors are better , FROM WHAT I'VE UNDERSTOOD it pays to look further , i am a bit suspicious of some of the info here , though i know i'm ignorant , and will finally have to choose who to believe

[@greggalexander5913]

I’ll suspect they injected chicken soup!😂

[@Vladamir8023]

Where did you get stem cell shots for 2k? I’m not seeing anything for less than 8k

[@milleklinda]

Great comparison. I've undergone PRP and amnionic stem cell injections and there was no comparison. Amnionic was far superior at my age; our stem cells get tired following chronic dis-ease and aging I would love to know where you're located as I'm researching for a friend who is not a candidate for knee replacement due to health conditions and would love to see him be able to have relief and regeneration. Thank you for doing such a wonderful job explaining each of the modalities. Blessings.

[@JeffreyPengMD]

Thanks for your comment! Glad to hear you found a treatment option that has worked for you. If you are in the United States, you can check the American Medical Society for Sports Medicine website to find a directory of board certified sports medicine physicians who may be able to help.

[@sirssays]

I would definitely look Into lifewave and the x39 patch! I've been using it for my knees for the past month and it's been amazing it's not that expensive and it activates the system in our body that produces our own stem cells

[@judyfasola3737]

Where did you have the procedures...PRP and stem cell injections .. thanks

[@andresavelar8352]

Where did u go for treatment

[@pmf1408]

Be careful with amniotic injections. No live cells. No independent research. Lots of fraud in that area.

[@Keepswimming....123]

Thank you for the comparison. It helps me look at the treatments in a much better light!!!!

[@JeffreyPengMD]

You're welcome! Definitely need more studies in these area, but so far it seems like PRP is an excellent (cheaper) option!

[@persiathiest1963]

Thank you so much for your good work! I was researching PRP and stem cell therapy for my mother's knee arthritis and had a lot of questions and confusion until hearing your summary. Please keep it updated as more research results come out.

[@JeffreyPengMD]

Thanks for your comment! My goal is to provide my patients (and everyone else!) with the latest clinical trial data.

[@bonnieweiss-mcdonald5436]

What about going to Mexico for MSC stem cell therapy?

[@olitonottero7620]

Thank you for sharing this DR. Jeffrey Peng !!

[@JeffreyPengMD]

You're very welcome, thanks for your comment!

[@arshdeepgill7842]

Thank you for this video doc! I have a question, you stated that Mesenchymal stem cells cannot regenerate into cartilage cells since they are not pluripotent but according to the Mayo Clinic they can differentiate into cartilage cells because they are still multipotent. Is this true?

[@JeffreyPengMD]

Thanks for your comment, the answer is fairly technical. MSCs can be induced into pluripotent stem cells in vitro (ie. in a lab). However, this has NOT been possible in vivo (ie. in the body). Because of this, many researchers have sought to reclassify the mesenchymal stem cell name to remove the "stem cell" component. One proposed name is "medicinal signaling cell" to keep the MSC nomenclature. The medicinal signaling cell name also is more accurate in terms of what the MSC is actually doing in the body.

[@kathryncooper4001]

I'm 73 years old, used to be an athlete, so wear and tear is an issue, and my knees are a train wreck. I've called twice to make sure, and my Medicare Advantage insurance company says PRP injections are covered. I might be too far-gone to fool with it, but I'm excited about the prospect of delaying knee replacement for a few years ... maybe forever. I tried Synvisc and Monovisc, and both worked for 6 to 9 months, but I'm hoping for greater, more long-lasting relief. X-rays tomorrow, then I'll see the specialist in a couple of weeks to see if I'm a candidate Thanks for all your very informative videos on the subject!.

[@JeffreyPengMD]

You're welcome, good luck

[@ineedhoez]

Read the plan documents. They will tell you anything over the phone

[@mistresssee1153]

Which med-advantage plan do you have?

[@kathryncooper4001]

@@mistresssee1153 Humana Honor for vets. However, it turned out that they WEREN'T covered. I had the injections, paid $1600, and netted some amazing results on one knee - like brand new. The other, which had only 1/2 its meniscus, was still problematic, and I ended up having knee replacement surgery last month.

[@PierreVB-514]

This is very good news ! Is PRP treatment also valid for other joints in the body ?

[@bharathsrinivasan1728]

Excellent insights about PRP Vs Stem Cell injections. Thanks for this.

[@JeffreyPengMD]

You are very welcome! Thanks for your comment

[@brucederouen6598]

Hi! Thanks for your video. Very helpful! I've had 2 root tears on my meniscus...one in my right knee, which ended up coming out after repair (my fault, NOT my Ortho's), so I had a subsequent surgery. After all that, i was having the after trauma arthritis flare up, so i went through PRP injections, physical therapy and bracing and stem wave and Im happy to say that knee is doing quite well. A few months later, my left knee decided it wanted in on the action and I had root tear there. :( I've had 2 PRP injections and am doing stem wave now with minimal results so far. Which is causing me to consider Stem Cell. I know this video is about a year old and in terms of technology and research,it could be considered a little out of date...maybe? (NOT meant as a criticism....please know that!) From listening to this, it seems your opinion is that Stem Cells aren't really better than PRP...is that what I'm gathering?! Thanks again for your videos!

[@lati_da]

Thank you for all the resources and bracing recommendations!!!

[@mhepdavidvanREI1]

Thanks doc. I got a quote on stem cell and it was quite expensive. So I’m gonna go with prp.

[@GEORGEFIRE777]

Good presentation, the treatments i have done ,they did help some but within a few weeks things returned as before. The treatments do not cure arthritis, they do not restore cushion so bone on bone is still an issue. I am now scheduling knee surgery .

[@rodrigosepulveda4559]

Hello, love your videos, thank you for sharing your kowledge, question: what about PRP and MSC stem cell shots one month appart? does PRP help the effectiveness of stem cells?

[@marktilsley8191]

Can you give a review of Arthrosamid please, this is old treatment

[@jr303official]

I couldn't afford prp injection into my arm with a torn tendon, but my Dr said we can try a blood injection and wow my arm healed in 3mo and the pain was gone. I had been trying to heal that arm for over a year with no success and that blood injection healed it.

[@JeffreyPengMD]

Wow, amazing!

[@5Things]

Awesome video Jeffrey, may I ask if you have any information on using umbilical cord stem cell as in Panama which were brought up by well-known people like Joe Rogan & Tony Robbins.

[@JeffreyPengMD]

I have a video on cord cells here: kzbin.info/www/bejne/gZWvgHmLfZ5qsKM

[@ramihanania69]

So Thankful for your videos Dr. ! May i ask, What do u think is the best injection for me, I had a sports injury in my heel, 3 years ago, healed completely, then 1 year ago, got reawakened cause of over exercise, Right now there is a constant sense of pressure in my heel area (similar to plantar fasciitis, but paradoxically, no pain first thing in the morning) I do exercise regularly and it helps .. Thanks again for the beautiful Work!

[@ramihanania69]

Took Nsaids for a long while 6 months ago, and dis some physiotherapy, It just seems like it's still not going back to normal after 1 year almost!

[@JeffreyPengMD]

Thanks for your comment. Unfortunately I cannot give medical advice over the internet. Please seek the advice of your trusted health care provider. Best of luck!

[@marilynjackson5752]

Wow, this was just was i needed to hear. I am looking for prp injections for my hips. Do you have that information?

[@JeffreyPengMD]

kzbin.info/www/bejne/sILYhImOhqxsY7c

[@arlenepuntil5634]

I got my PRP injection here in SYDNEY AUSTRALIA..it fells better...after 3 weeks I didn't feel any pain in my knees...how many months before you take another shot for PRP..

[@granitveseli9409]

thank you for explaining the regenerative therapy so well. I have a partial high grade PCL tear and my knee feels unstable. I am hopeful to try stem cell therapy to correct this problem so i can get back to full function and play sports as i was before. The orthopedic surgeon that i recently saw told me stem cell therapy speeds the healing but will not correct the torn ligament and that i will need surgery if i want best result. Any comments about umbilical cord stem cell therapy being more potent, what is a good center that provides this service. I want to try this less invasive method only if high chance to work. I see it works for arthritis, but not sure about torn ligament. thanks

[@cheliospanama9786]

Great Video! Thank you 🔥👏💪🫶

[@beefwellington3180]

I’m in Texas and paid $650 for PRP about 2 weeks ago for my cracked cartilage in knee. I’ll be watching the results. Thus far I feel like the aching from PRP is somewhat still lingering. Sometimes I can’t tell from the original pain vs aches and my body adjusting to the PRP. My orthopedic told me the aches should go away after a week so I was a bit confused. I originally got the injury from a sprained knee from a kick(I do kickboxing). So whenever my weight shifts around from one side to the other when boxing, I’ll take note of what exactly happens during my shadow boxing with that cracked cartilage and if the pain lessens over time from the PRP. I’m 28, almost 29

[@tomikk86]

let us know please

[@beefwellington3180]

@@tomikk86 will do. I’ll probably be back here in like 1-3 months to say

[@JeffreyPengMD]

Good luck!!

[@samuelcorleto7106]

Keep us posted !

[@chill0087]

How soon after are you training again. And what kind of training?

[@jackshrimp]

Can u pls advice if Stemcell & Platelet treatment helps in lower back issues

[@wethepeople3381]

HI Thank you for your effort to create such an informative video. May i ask, does this STEM CELL AND PRP method effective with Osteoarthritis in both hips also. I live in the UK. Many thanks in advance.

[@amenahossain3464]

They should cover PRP and Stem cells.

[@JeffreyPengMD]

100% agree!

[@claud1834]

I understand active military insurance now covers PRP injections. This info came from my PRP doctor in Monterey CA. PRP worked very well for me for 2 years. I need to have injections again after 2 years.

[@jackie-k]

The VA does. They did my left knee but won’t do my right as it is too damaged they say.

[@lindahelmbrecht1248]

I had two PRP injections in 2015/2016…….2023, still no pain like before……no swelling

[@JeffreyPengMD]

Awesome!

[@joellabrie-ki9bk]

Which is better for arachnoiditis . How do you know if they’re putting dead cells in you not going to work

[@kenofken9458]

I'm considering PRP for severe and chronic Lateral epicondylitis. I've seen some positive studies but also some which seemed to show that it may have been the action of the needle itself that provoked any healing.

[@JeffreyPengMD]

Needle tenotomy alone can definitely help. I do it for patients who are unable to get PRP and don't want steroids.

[@kenofken9458]

@@JeffreyPengMD I might have to look into either. Had a couple steroid shots in one elbow and they definitely helped for months at a time, but it seems to be a losing strategy long term where tissue breakdown is concerned.

[@rosiecarter9831]

Hi what about hip arthritis would both or either would work on hip arthritis if needed a hip replacement surgery?

[@JeffreyPengMD]

kzbin.info/www/bejne/ZqS9dqmshbykbpo

[@timothybright7064]

I had 3 Injections of PRP after I had My Gainswave Treatments for Ed on The 4th of March. I'm told to wait 4-8 weeks to See The Results! I have too Pump Two to Three times a Day & Two is enough, and I'm tired of doing that! I Heard Stem Cells supposed to be a Game Changer! I have Issues with Spinal Stenosis, Bad Knee, Shoulder, I want to look Younger without Botox or Surgery! Also I prefer my Testosterone Levels Reached Naturally with HRT/ Testosterone Replacement. I'm curious if Stem Cells benefits Haire Growth. Thanks.

[@JeffreyPengMD]

Hair growth is definitely not my area of expertise!

[@ivet7870]

Hi doc, can PRP help treat chondromalacia patella grade 1? I’m 25 years old. I heard that they can combine it with MSC, will this help me better? Can they inject hyaluronic acid too like the 3 of it together or one after the other with some time gap between each one of the therapies? What is the best option for me? My knee hurts under the patella and cracks+crepitus when I straighten it or raise out of sitting position. I can’t go up or down stairs. Can this be fixed with these therapies? Also I do physical therapy but I need to do everything to save my knees until it’s not too late bc I really need to return to active lifestyle.

[@JeffreyPengMD]

Yes PRP can help treat grade 1 chondromalacia patella. There is no evidence of combining PRP and MSC. I do recommend interval HA injections as well for maintenance therapy. You will need to discuss with your health care provider how to individualize treatment for yourself. Best of luck!

[@jennifermikuluk2357]

I’m hoping to participate in Dr James Voos study. MRI to evaluate before and after stem cell, from BM. 2 year study. I’m 6 months post op RTKA, would like to save my other knee from the same fate. If I don’t end up a study participant I’ll pay out of pocket for PRP. Any thoughts about how to find a reliable physician to trust giving PRP? Seems like so many out to make a buck, makes me nervous.

[@JeffreyPengMD]

Your best bet is to find a sports medicine physician who does the injection under ultrasound guidance. Easiest way to find someone who does this is to search for a "primary care sports medicine" physician. We are also called non-operative orthopedists. I have not come across many orthopedic surgeons who do these injections under ultrasound guidance. If you are ever told it doesn't matter, that would be a big red flag. Surgeons are trained to operate, which they do unbelievably well! But they may not have the training to do injections under ultrasound guidance. If you are lucky enough to be around an academic institution, pretty much every academic institution will have someone who does PRP injections regularly and under imaging guidance.

[@batman-sr2px]

@@JeffreyPengMD Some pain management is also doing them. I don't know if they do under ultrasound so thanks for letting us know and i'll try to ask. In your experience, do insurance cover prp/stem cell treatment if sports med doctor submits the claim and conservative/physical therapy has failed? i have just researched that muscle fibers have limited stem cell. So when they get exhausted due to chronic injuries or trauma, the body cannot produce more?

[@g.marinestation3236]

If you live close to Mexico they use a Drug called Bedinvetmab the Brandname is i think Librela. This is a Drug for Horses and Dogs but i got years of all of this what he talks up there and had pain pain pain, after the first Injection i was the first time in years painfree. This are some monoclonal antibody Cells from China and they work. I mean they w o r k! I know you have to go a long way to decide to take Horsedrugs in Mexico, but i feel sooo good. I had 2 Inj. in 4 weeks and now its more then 12 months that i didnt need any NSAIDs at all. I wont recomend Librela here because i am not a Docter but it helped me a lot and i want to share this. In the US its not labeled for human use!!! One shot in Juarez is 80 bucks. I paid 150 for both shots.

[@geopietro]

This video was a truly excellent presentation, both informative and practical. Thank you Jeffrey!

[@JeffreyPengMD]

Glad you found it helpful! Thanks for commenting

[@mzreid6386]

Feedback?¿

[@PRESA25]

What if both used together?

[@123Goldhunter11]

Umbilical tissue/cells seems to be the superior treatment. But you have to go to Mexico to get it.

[@JeffreyPengMD]

Thanks for your comment. In my experience, I advise all my patients to be VERY careful with umbilical products and providers who sell you on their benefits.

[@galuhrismawan3401]

sorry, what do you mean about sell yourself for their benefits ? it seems ucmsc dont give a good treatment ? or its just a good for promotion than for treatment

[@markmendelson6688]

Umbilical cord msc stem cells are more potent than your own bone marrow derived cells..however they are not available in most countries because the big pharma controls regulation

[@BadWolf1958]

I had my first stem cell injection today. They also had a machine that expanded and contracted my knee. I will be going in twice a week to use this machine. No pain from the injection. I will post updates as my therapy progresses.

[@Gobrowns123]

How has it been so far

[@BadWolf1958]

@@Gobrowns123 I got my 3rd and final injection yesterday. My knee is better 2 months down the road. Dr. told me in 6 months to a year for the healing to stop, with a 6 year life of the injections. I can stand for 3 hours without much discomfort. Walking is getting better. Still have my good and bad days.

[@Gobrowns123]

@@BadWolf1958 I hope it keeps getting better

[@BadWolf1958]

@@Gobrowns123 Thank you

[@slair5948]

hi how r u ? where dod u get it done how much? im. from the uk woth degenerative disc disease

[@kidneymd1962]

Great video. I’m 5 months out of partial menisectomy of my right medial meniscus. 30% removed. I’m feeling knee pain on the medial side and in the back of the knee. I’m worse off after surgery than before. I’m so depressed. I know I haven’t aggressively rehabilitated with PT and my quadriceps strength on ipsilateral side is much weaker than opposite. Should I consider these treatments now or really ramp up PT? If yes, which one PRP or Stem Cells?

[@JeffreyPengMD]

You may find this helpful: kzbin.info/www/bejne/np62pH2dpcxjac0 kzbin.info/www/bejne/sGTZlph3nLdrd7M

[@kidneymd1962]

@@JeffreyPengMD Thank you. How I wish I had seen your videos before surgery. So now I have a menisectomy and post op pain. Can PRP and PT still help at this point?

[@JeffreyPengMD]

​@@kidneymd1962 In general, yes PRP and PT can help. But your individual situation needs to be discussed with your health care team.

[@keithrichard391]

I have had 30-35 PRP treatments& 3 stem cells procedures over ten years...and I can honestly say Stem cells are way better(10 times superior) in my results!!!!!

[@JeffreyPengMD]

Glad you found something that works for you!

[@TH-qv6ef]

How do you explain pre and post xrays and MRI's showing regrowth of cartilage?

[@JeffreyPengMD]

Show those results to me in a large sample randomized controlled trial. For example, did you know some ACL tears heal on their own? It was previously thought ALL ACL tears require surgery. There is now evidence that a small subset of patients who have ACL tears can heal spontaneously. Perhaps these are the patients that get "magically cured" with biologic treatment. The same is true for cartilage and *insert whatever condition here*. This is why large sample randomized controlled trials need to be done.

[@champicagunasekera453]

Is this method only for knee arthritis? Can it done for the hip too? Thank you

[@JeffreyPengMD]

Yes

[@stephenyurica9834]

I had one injection in my knee, 4 months ago. Much better. I thought I needed replacement. Now I´m thinking of another PRP to enhance my progress. Do you recommend several PRP injections over time?

[@JeffreyPengMD]

Yes, maintenance injections are typically recommended

[@stephenyurica9834]

@@JeffreyPengMD Thanks I have it done in Costa Rica. The alternative medicine here is getting popular , finally we have more choices instead of knee replacement. Muchas gracias.

[@tahsenhossain3749]

Some regenerative specialists says that those therapies regenerate the cartilage at stage first and mild.What do you say sir?

[@JeffreyPengMD]

I too really hope that this is true. However (to date) there is no clinical evidence that this statement is true.

[@richardelkins5265]

Ty Dr you just answered a major question as I had stem cell treatment in my shoulder and it worked wonders I am having PRP in my left knee on sept 7 22 and was concerned about how effective it would be. Thank you so much for the info it will save me a couple of thousand dollars

[@JeffreyPengMD]

You're very welcome! Thanks for your comment

[@ivet7870]

Hi, can you please share which exactly stem cell treatment have you done?

[@persiathiest1963]

How is the PRP working out for you? Any visible improvments?

[@richardelkins5265]

@@persiathiest1963 I get it n the 7th f sept

[@richardelkins5265]

@@ivet7870 mine was taken from the hip worked great on my shoulder

[@sunnymelindalinarda5625]

Thanks dr. Peng for the comparison. Do you know about Prolozone injection therapy ? How about it for knee arthrities, especially for grade 3-4 ? Which is better, PRP or prolozone ?

[@JeffreyPengMD]

Prolozone has not been studied as much as PRP has

[@graemeandrew8643]

Hi DR peng.. two questions. are these prp and stem cell injection treatments available in Australia? And is it an option for people with rheumatoid arthritis?... I recently had a MRI scan on my knee. Finding small knee joint effusion, near full thickness cartilage loss at lateral aspect of medial femoral condole with defect of 8mm..prominent osseous oedema of medial femoral condole is evident likely reactive....everything else is normal....so I don't know exactly what I'm dealing with..the GP said I have lost cartilage.....I'm seeing a specialist in two days time..but I don't understand what I even have .I mean I don't think it is arthritis .... based on the information I have given I'd appreciate your feedback thank you

[@Cent4man]

I had a Synvic injection in one one and it was useless. I felt better for about 2 weeks and now it’s as bad as it was before the injection. Both knees need fixed. I’d like to make knee replacement a last choice. I’m hearing stem cell therapy works great and a friend of mine is happy with his treatment years later. What should I ask my orthopedist to try now?

[@JeffreyPengMD]

Thanks for your comment. Best to discuss all your options with a trusted health care provider. Good luck!

[@mtease9247]

My problem now is I need my more arthritic right knee done. I didn’t do both 9 yrs ago, but definitely should have. Finances played a big part in that. But I still want to give stem cell atty before total knee arthroplasty! Thing is I’m 61 yrs old now & my stem cells are 9 yrs older than last stem cell procedure. I’m very interested in using allogenic MSC’s from umbilical cord. It is being done in this country and out of the US. Thing is I want a definite answer about safety, efficacy, and how viable and the amount ! Not to mention I don’t think there’s a gold standard protocol that is used. It’s hard navigating this info ! I’ve heard it’s very successful and problems would only come from placenta stem cells…, rejection, cancers, ect …. Can and will you advise ???

[@JeffreyPengMD]

I can't comment on the procedures done outside of the US. But in general, I advise my patients to be VERY careful as more often than not, these are not regulated clinics.

[@christophedupont2595]

Hi could you give your opinion about subchondroplasty (knee and hip) ?

[@claudeviger8801]

What's the results for spine discarthrosis and herniated disc on pain relief and repair? I know the subject is for knee problem but i have these and still waiting for stem cells injections in spine for 3 years now as anything else failed from 13 years of meds and peridurals...Thank you.

[@JeffreyPengMD]

You may find this informative: kzbin.info/www/bejne/lYq9co1ti9lld9U

[@HelenaMulio]

Is PRP Suitable for Hip osteoarthitis ?

[@reimleinreimlein9767]

Does injections has the same effect on knee arthritis and chondromalacia patella?

[@JeffreyPengMD]

Yup

[@agrow21]

Hi Dr. Peng - I looked at your website and are you not offering stem cell therapy anymore. If not, why? Would love the opportunity to speak with you about personal stem cells.

[@028fn48dne]

Isn't all stem cell treatment for orthopedic conditions illegal in the United States?

[@jamespolucha8790]

I thought we don’t do stem cell injections in the USA , I heard we make stem cell in San Diego but need to go out of the country to have it injected, is this correct? I met a man that was bed ridden with a bad back went to Mexico for stem cell injections and is back at work same with Gorie Hawl the hockey player had a stroke and went to Mexico for stem cells and is doing great

[@JeffreyPengMD]

Currently you can harvest fat MSCs and bone marrow MSCs in the US for injection treatment. Culture expanding is not allowed.

[@demonstration3662]

What about for hip joints? 😢

[@jroth3792]

How about allograft tissue especially for those older patients for example do not have a high ratio of Bone Marrow cell - MSC production?

[@JeffreyPengMD]

This is not currently legal in the United States. Maybe one day

[@maltikuntawar2373]

What is sanakin therapy which is better sanakin or stem one injection

[@JeffreyPengMD]

These are all derivatives of PRP. PRP has been the BEST and most extensively studied option and is currently my most recommended treatment.

[@joebruhin2098]

Hello Dr, do you give stem cell injections at your clinic?

[@rickbackous1041]

Someone help me. Where can I find a PRP injection clinic in Florida?

[@mtease9247]

Do you use the WOMAC scale for your information?

[@JeffreyPengMD]

Yes

[@mtease9247]

Your correct bc after 9 yrs my stem cell procedure worked & still going strong ! But X-rays do not show increased joint space. Not true bout not working if bone in bone … but then Drs use that term very loosely imo.

[@JeffreyPengMD]

Thanks for commenting

[@chaityfatema8883]

Did you have bone on bone stage of osteoarthritis? Did stem cell work for you and you can walk normally without pain now?

[@Ramsangthakor4]

Knee ostechondral zise 2cm plus best treatment? Otsa and mosaicplasty vs stem cell injection best?

[@JeffreyPengMD]

Thanks for your comment. Unfortunately I cannot give medical advice over the internet. Please seek the advice of your trusted health care provider. Best of luck!

[@Pawnlust]

What about exosomes vs these two?

[@ravivermaverma5573]

Thank you for kind information We want more vedios about spinalchord disc problem new research regenerate treatment vedios Next 10years , the real pandamic is spinal chord disc problem issues in youngers.this is true

[@JeffreyPengMD]

You may find this helpful: kzbin.info/www/bejne/lYq9co1ti9lld9U

[@linacarol7344]

I had PrP treatment three injections (one every 2 months) I did not feel any change. I had to take steroids to calm my pain.

[@DyanneTaylor]

Love it but I have wanted for shoulders.

[@mro3072]

Is PRP used in any other part of the body? I have arthritis in my spine and I'm wondering if it has been used there and whether the treatment is available to the public?

[@JeffreyPengMD]

Yes, PRP has been used for almost every part of the body. It is much less studied for the spine. See here: kzbin.info/www/bejne/lYq9co1ti9lld9U

[@michaelgarcia8019]

What is better prp or prf for treating cartilage ?

[@JeffreyPengMD]

PRP is MUCH better studied. Unfortunately there are not many randomized controlled trials studying PRF

[@awaisshab]

very informative. thanks

[@SRIRAMGURUMURTHY]

Hi sir !! Can you please let me know whether hydraulic acid + PRP injections together work for chondronmalacia patella grade IV? I am facing chondronmalacia patella Grade IV now and the ortho doctor suggested for this method.

[@mellow_mel1313]

Does prp and marrow stem cells still perform the same with stage 3-4? I had someone suggest that prp does better for stage 1-2 and not as well after it has progressed

[@JeffreyPengMD]

PRP and MSCs are less effective for stages 3&4 when compared to 1&2.

[@iteleshov]

What do you think about hip injections?

[@Dggb2345]

Thank you. Loved use of meta analysis

[@JeffreyPengMD]

Thanks for your comment!

[@DextrFV]

I recently just got a minor labrum tear from pitching and I opted not to do surgery because it is my senior year. Would PRP be better than the bone marrow injection in my case or the other way around?

[@sharaudramey9336]

How'd it go?

[@jenperdsmonlapin6953]

I know this is about knee therapies, but I have arthritis in my wrist for years now and tried many things including PRP that didn't work. Is there any chance to get better results with stem cells? I have given up on many things that used to give me pleasure in life because the arthritis felt like such a handicap I'd just feel frustrated instead of enjoying myself. I feel like my life has been put on hold since this condition has started affecting me, I'm focusing on my work at the moment waiting for some miracle that might not happen to get back to my hobbies one day hopefully...

[@JeffreyPengMD]

This is a complicated question and the answer is just as complicated and needs to be individualized to your specific situation. Best to discuss with your health care provider. Good luck

[@-xyz-012]

If your willing to look to a natural therapy, try grating ginger & make a poultice, wrap it over the wrist, then wrap plastic wrap over it to keep in place, leave it on overnight. It draws out inflammation. Keep doing it until pain is gone.

[@kennethmarquis6307]

Can these ve used for maximus minimus injuries?

[@JeffreyPengMD]

If you mean gluteal tendon injuries, then yes. PRP has been studied for gluteal tendinopathy and works very well.

[@dantenappi5655]

What about PRF. Platelet Rich Fibrin. Can you do a comparison between PRP and PRF. Ty

[@JeffreyPengMD]

PRP is much more extensively studied than PRF.

[@ttscrafts6765]

Does it matter what type of arthritis the patient has for PRP treatment? There are so many types, with many being autoimmune conditions. I hope it does not make the autoimmune reactions more.

[@JeffreyPengMD]

Yes -- almost all of these studies are looking at osteoarthritis. PRP has not been well studied for conditions such as rheumatoid arthritis. Thanks for your question.

[@nerlyb7032]

I have an anterior labral tear my doctor told me to try with PRP injection hoping the pain goes away 😢

[@JeffreyPengMD]

Good luck!

[@crystallite1974]

Can prp injections work for RA patients?

[@samr5559]

Have you considered amniotic injections?

[@nasimmaniyar2972]

Hi Dr i m Ayesha here i had accident before 1 n half year ago i have cartilage injury as well as minuscus tear i took Halloween gel injection before 1 month ago and tacking supliments what should i do please suggest me

[@Carlosruiz-vb4xo]

Hello yo I'm just talk about knee arthritis but what about minor tear of the rotator cuff??? Please let me know as I am getting ready to do PRP. Thank you

[@ednaberenicegaleano5413]

Would those treatments work for chronic plantar fasciatis?

[@JeffreyPengMD]

Yes, it does! Here's more info: kzbin.info/www/bejne/rZ_JoGZ6qrV-b6s

[@ednaberenicegaleano5413]

@@JeffreyPengMD thank you for replying to me Dr Jeffrey 🙏🙏

[@kevinswaney5875]

I'm curious if this would apply to a senior with a torn meniscus? It seems my stem cells would not be that beneficial at age 65?

[@JeffreyPengMD]

We know that as we age, we have less MSCs in our bone marrow. This is why in theory adipose derived MSCs would make sense as there are plenty of cells in adipose tissue. With that said, PRP rely on platelets and growth factors, which you make throughout your whole life. No need to worry about MSC counts with PRP.

[@kevinswaney5875]

@@JeffreyPengMD thank you