Ossifying Fibromyxoid Tumor (OFMT) of Soft Parts

A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).
Ossifying fibromyxoid tumor (OFMT) is a rare soft tissue tumor with a very distinct appearance. This video discusses how to make the diagnosis. For more info about criteria for atypical and malignant variants of OFMT, see this paper: www.ncbi.nlm.nih.gov/pubmed/1.... Thanks to my dermpath fellow, Dr. Ed Fulton, for selecting the topic for this video.
Please check out my Soft Tissue Pathology & Dermatopathology survival guide textbooks: bit.ly/2Te2haB
This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.
Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos.
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[@JMGardnerMD]

A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).

[@theyeetboyz6838]

Very nice condensed lectures, I like all your lectures being loaded with all the informations in a short video,

[@donyatohidi-esfahani7816]

You are the bestest. Thank you for sharing your teaching 😊

[@diviloveable]

In my residency I miss such classical teaching, thank you Sir for sharing your knowledge with us

[@drsaradindudas5859]

Thankyou sir for sharing your knowledge and experience

[@shirindasgupta6519]

Great teaching sir..love your videos

[@yasirmohammedali]

Hi doctor, thank you so much for the video.

[@user-cn2zu8qp5u]

Thank you Sir! i love your videos!

[@htg4666]

Thank you so much for sharing these beautiful and so helpful pathology videos. Your youtube channel is one of the best resources for learning dermpath & soft tissue pathology. I have a question please, Is there any relation between " Ossifying Fibroma" and "Ossifying Fibromyxoid Tumor (OFMT)" ? Is it true that " Ossifying Fibroma" is a subtype of " (OFMT)" that have no myxoid component?

[@JMGardnerMD]

Ossifying fibroma of jaw? No relationship to OFMT to my knowledge.

[@JMGardnerMD]

Also thanks for the very kind words!

[@LOLsaudi]

an example of a pleomorphic tumor with a translocation is myxoinfialmmatory fibroblastic sarcoma.

[@JMGardnerMD]

Yes there are a few exceptions to this rule

[@yasirmohammedali]

Is there an association between the desmin expression and the morphology in some slides where it looks like a merged mass of smooth muscle

[@JMGardnerMD]

Not to my knowledge. I don’t think we understand exactly why this tumor sometimes expresses desmin.

[@sharryngilmore-feuerstein4289]

was wondering, are these cancerous tumors? What does malignant and locally aggressive mean in these types of tumors?

[@JMGardnerMD]

Hi Sharry. "Locally aggressive" usually means that a tumor has the tendency to grow back in the same area after surgery, sometimes multiple times. Malignant usually means that a tumor has the ability to spread to other parts of the body and could potentially be fatal. Ossifying fibromyxoid tumor is a unique tumor that does not fit neatly into the rules. Most cases have a good behavior, but there are some cases that can show malignant behavior. Usually, the malignant ones have certain features under the microscope that the pathologist can recognize to help us identify the cases that have higher risk of behaving badly.

[@redpooh5]

What can cause this cancer? Can it not go away for good?What’s the chances of growing back?