Khan Academy - The Basal Ganglia: Details of the Indirect Pathway

[@mehdi1743]

having a little puppy thats a little bit of a trouble maker, i completely related with the example of this video. really helped me understand the vid! really nice vid

[@blueberreez]

This is so helpful! I'm taking a class on motor speech disorders & I was having a really hard time getting these pathways until I saw your videos. Thank you!!!

[@TheDontate0]

You are amazing thank you so much. great handwritten great examples a clear voice and lots of pictures. I genuinely wish I could trade you with my professor.

[@giannithiago1267]

i guess it is kinda randomly asking but do anybody know a good website to watch new tv shows online?

[@emya1945]

I like the puppy and leash analogy. It made it easier for me to understand.

[@lisagonzalez2902]

Honestly, this video is very well made. This visual resource is awesome, with colorfulness and simple yet funny examples to aid my understanding!!

[@Sevival]

sometime i wish my brain was more simple to study so my brain can study itself more easy. #justhumanproblems

[@joel2403]

Emma, this is fantastic work! Thank you for taking the time to make such a wonderful set of videos!

[@KateTolhurst]

Thank you so much! Khan Academy has basically got me through everything so far! Your explanations and analogies are fantasic :)

[@raya9664]

this is amazing , you illustrated it in such an easy clear way , thank you.

[@meerapurnachandran5095]

Dese explanations r amazing! Make more videos! They are REALLY helpful!

[@Dupenois20]

Thank you, I really enjoy your videos. this was a massive help

[@SasaTommo]

i love your videos! it makes everything easier.. thank God i found your channel

[@aarias13161]

Thanks for the video. I did not learn this well in Neuroscience, but now I definitely feel more comfortable with it.

[@nrogersc]

puppy on a leash... best analogy ever. Thanks!

[@mkn309]

I love how clear your explanation is and your puppy metaphor is golden. One question: the role of the SN your discuss, is that referring to the pars compacta (SNc)? Or is there some SNr in there somewhere too?

[@GuiCastro96]

When I leave the dorms of med school and be able to have a dog again, I'll certainly name it thalamus haha. Amazing video!

[@charlesrock2746]

Thank you! Very clear explanation.

[@tmacinorbit]

I believe there is an error in the video. Dopamine on D2 receptors will increase the indirect pathway therefore decrease movement. D1 receptors increase direct pathway leading to more movement.

[@ae7452]

ya i was thinking the same thing

[@katepetter3063]

dopamine D2-receptors decreases activity of the indirect pathway - which means more movement. (also D1 receptors in direct pathway increases movement) Action of dopamine increases movement both ways.

[@miseker32]

This is absolutely amazing! Thank you so very much!

[@aBigBadWolf]

When you say they talk to each other, should I imagine this more like a power station or actual movements encoded in the communication?

[@chelseybrown3905]

This is absolutely amazing and helped so much on my Neuro Exam! You should make more about the Hypothalamus, Limbic system and Cerebellum :)

[@dspvlogs773]

great video mam...love from india....

[@ksufler]

I'm able to understand everything about this except the first step. In the Direct Path video you said, that motor cortex first communicates with the striatum and striatum blocks the activity of G. Pallidus Int. And in this video you say that when striatum is excited by a signal from the motor cortex it inhibits the G. Pallidus Ext.! So, my question is, how do Striatum know, which part of GP it should talk to after receiving an impulse from motor cortex? And secondly, if the aim of indirect pathway is to keep up from moving why does the pathway start with a signal from the motor cortex? That doesn't actually make sense to me :(

[@cj7ification]

+ksufler Answer is simple. It depends whether the motor cortex wants to activate the direct or indirect pathway i.e (does it want to increase movement or decrease movement)

[@KateTolhurst]

+cj7ification but how does it know?! It excites the Striatum either way - are there different exitatory neurotransmitters from the motor cortex to the striatum? Thanks :)

[@salhasabeeha2010]

check meetpatel,s youtube video on basalganglia pathways. you shall get it cleared.

[@brettnibler8874]

so about that first date...... I have this weekend open

[@angelphish007]

Lol thanks for the laugh as I desperately cram for MedChem

[@umeshcharitha1245]

Mam can u please add subtitles for upcoming videos like previous i.e,direct pathway of basal ganglia

[@oliviafleurbaey2441]

THIS IS AWESOME! THANK YOU SO MUCH

[@sweetiedoll9613]

So helpful ! Thanks so much :)

[@ftufaif]

Very useful! Thanks!

[@شيخةأحمد-ت2ش]

Nice voice .. so comfortable

[@krog9513]

I love your videos. Thanks. :-)

[@traceymontgomerie9272]

awesome analogy! thnx!!!

[@jakejohengen4052]

You are amazing thank you!

[@sarveswaraiahjangam2248]

really good lecture more helpful

[@zaidkhalaf6102]

awesome

[@alihassan-nl2cl]

Awesome

[@Jdizzl111]

Agreed!!