Overview of glycolysis | Cellular respiration | Biology | Khan Academy

[@Everchanging88i]

Definitely amazing how effective your lessons are. Overview i think is one of those things that are really not appreciated by the vast majority of teachers, and yet an understanding of the whole is at the heart of learning, and understanding anything. Your lessons because of the clarity they give of a concept, help establish the idea firmly.

[@ilaila3504]

this is bang on the level needed for my course, human cells at higher biology level SQA. I have spent two days trying to get understanding of this process, so i will pass on a message that if you are struggling like i was - you will need to watch this process over and over again until it starts to make sense. thanks mr khan

[@TomoyoTatar]

FINALLY I UNDERSTAND AFTER HOURS OF WATCHING WEIRD THINGS ON KZbin

[@JohnFernandez414]

Salman Khan, once again saving me on the bus ride to school before a test.

[@Lycroo]

Me too！ XD

[@anindyahani7773]

John Fernandez he becomes a hero for everyone 😆

[@veryrisku1119]

@Robert Morgan It's been two years i doubt he'd remember

[@thesmiler119]

@@veryrisku1119 it's been 1 year i doubt you'd remember!

[@rkfootball3409]

@@thesmiler119 Its been 4 months I doubt you'd remember

[@thatweirdo93]

My IB bio teacher loves you, he used your videos in class all the time! I have my HL exams tomorrow, and because of you I'm so much more comfortable with the material. Thank you, keep it up!

[@24jonasluv]

I really appreciate your time and effort in making these videos! It really shows your personality! I am an AP BIO student, and my teacher never goes over the material, but thank God for khanacademy! Thank you so much! I hope you realize you are saving millions of high school kids around the world :) Thank You!

[@khashayarmastoori1]

Thank you, you could explain it in 13 minutes but it took my lecturer an hour .

[@charlotteparker2051]

No literally my professor spent two hours explaining this

[@baileyedwards4530]

The background is white and this hurts me.

[@udkmyname5251]

Aww it's okay

[@bjones5491]

lmao

[@mariep5227]

He was really struggling to write ADP

[@yanda6732]

You're the kind of people who pay attention to the wrong things during class 🤣 7:00

[@evrist1500]

i was laughing so hard ngl

[@kalef1234]

He knows science too??!!!! I love khan academy.

[@arvinian01]

ETC - means " end of thinking capacity"

[@TheCanadianGuy08]

DUDE YOUR A LIFE SAVER thank you soooo much for this vid I've got a bio mid term coming up and my prof is extremely hard to pay attention too these cycle vids are gunna help me so much

[@hullah3000]

if you set the speed to 0.5, he sounds drunk lol

[@XxlethalDJxX]

AHAHHAAHAHA

[@123tomandadrian]

hahaha!

[@Rushil_Sudunagunta]

he sounds like a little girl when speed is set to 2

[@mohammadabed4041]

lol

[@MagentaFerret]

Rushil Sudunagunta he sounds high

[@shikinhlm]

Hey!!! Thank you so much for the clear explanation. It really helps in my understanding. You teach way better than my lecturer. He spent 1 hour teaching but I don't underdstand anything. Whereas, you only spent about 13 minutes and I am able to understand almost everything. Once again, thank you for being a great teacher. Totally appreciate it. :)

[@hbarker216]

Thank you for making this video. I am taking Bio 111 in a Community College, I have shared this video with some of my classmates to help them out. I feel that this explanation is very easy to follow and will help me learn. When taking notes in class this doesn't make sense because while we are writing everything down, there just isn't enough time to understand what I am writing! This way is almost like I am listening to my teach again and I can do so several times until i understand the concept.

[@新野心]

I really feel like giving him bro fist each time i listened to his video, to thank him. :D

[@sparkleandshine2494]

Understood way better than when my Bio teacher went over it, thank you Khan Academy!

[@raider968]

I don't know why but my brain shuts off the moment I lay my eyes on a text book.. But thankfully, there's Khan to save the day.

[@Bbarbiexox]

I have a major micobio exam on monday you have taught me what my instructor attemped for 3 hrs in 15 mins or less you rule!!!

[@Jade808]

I have a Biology test tomorrow and I have understood nothing this entire unit until I found your video. I finally get Gylcolysis and Cellular Respiration, so thanks! :) ~Jade808~

[@attiya5471]

I was just wondering, I mean if you wanna share about where are you in life Now?

[@214aleksandra]

i think you are genius, because you made everything so simple, and nature is simple but other people made it too complicated because they want to feel smart or special, but thats not real point of learning

[@mk-vp8bg]

my bio teacher requires us to know SO much...like how glucose is split into PGAL -.- there are so many steps in between, ahhh so nervous for my test tomorrow.

[@DinaAwd]

Same here

[@fahtihaishak]

Same ARMY same ...

[@maggiewang5285]

mood

[@DannyBridie]

2 yrs later and you’ve passed your nervousness on to me. Yay biology!!!! Yeah!!!

[@hannahdivic28]

Sameee test in 2 days and I’ve tried learning so much and am still so confused why is this so complicated

[@Suh6727]

It really helps if you remember the steps before looking at the big picture.

[@sylvanpine]

3:15 "Phosphoglyceraldehyde really challenging my spelling skills here" LOL 😅

[@jacobvs98]

Thank you so much! Better explanation than my teacher's one..

[@jahnavimishra7166]

Thankyouuuu sso much sir am from india and i was preparing of medical entrance exam that is( neet ) am really struggling with plant physiology chapters no doubt we have also a lot of good teachers but i dont know am not able to get it i don't know how much vidoes i have seen but then i suddenly remembers your channel and you r my life saviour and thnkyouu soo soo much sirr❤❤❤❤lots of love from india

[@radiacto]

basically the 2 phosphates are taken from the 2 ATPs so that glucose can be phosphorylated, and a step that isn't shown is that as a result of this, 2 molecules of triose phosphate are created and 2 molecules of ADP, because the 2 phosphates have been taken from both ATPs, therefore there are only 2 phosphates left so ADP is produced because it is di-phosphate. Hope that helped

[@memeyaa3780]

this saves your life when you have a test tomorrow and you dont know what the hell was happening in class, now i can totally slay my test tomorrow -hopefully lol- thank you very much though

[@yoojunnguyen9866]

Thank you so much. I have an exam on Tuesday and this is just what I was looking for. It makes a lot more sense then sitting and reading my book for hours trying to figure what the heck is going on.

[@sKHANcreative]

KHANS are always the best ........................ Keep it up we all are your students and you are our best teacher

[@cdaniellemalimban]

CrashCourse vs. TED-Ed Winner: CrashCourse TED-Ed vs. Khan Academy Winner: Khan Academy CrashCourse vs. Khan Academy Winner: Khan Academy 1st Place - Khan Academy 2nd Place - CrashCourse 3rd Place - TED-Ed :)

[@inkbery4473]

Danielle Malimban I feel like Khan Academy is best at preparing students, Crash Course is more for the fun of knowledge, but it still supplies students with a helpful guide, and TED-Ed is purely a "the more you know"-type channel, not meant for studying off of... So that's why Khan Academy is better for you, probably studying, right? 😊

[@holfletc]

I thought I'd never understand this stuff... ever. This is helping immensely. Thanks

[@vitalal]

thank u for this! u so much better a teacher than my actual teacher

[@jacobthuesen7006]

Great lesson! Biology exam tomorrow and this helped alot! Thanks! You're over 9000 times better to teach than my biology teacher!

[@supaahflyy]

explained it miles better than my uni professor. Mind you i ended up just rope learning it and still getting a Distinction but i didnt actually understand the process. Thankyou!

[@DeejM92]

You're one of a kind, and I actually love studying Biochemistry with you even though I despise it. Thank you so much! Hugs from Saudi Arabia (:

[@carmelb99]

Very helpful. Many people tried to explain it to me, but nobody explained it as well as you did. Thank you so much :)

[@smaina1499]

You just saved my academic life. Thank you. ❤😭

[@shonaragibson]

Have you done a video diving deeper into the enzymes/intermediates/regulation of glycolysis? Would complement this nicely and would help out with the more complex aspects students may need to know. Love the videos, keep em coming! :)

[@Leeanne1967]

WOW for the first time I actually understand this...a thousand thank you's!!!!!!

[@SharletC]

Really wanna thank Khanacademy for all the videos made. Even my school (Republic Polytechnica, Singapore) uses your video as a resource for us to have better understanding. :)

[@Coyoteari]

I learned more from this video than from the hour and a half cell bio lecture I had to sit through on it

[@rockett2mann5]

I watch your videos to study cram... Works everytime

[@appslover1232123212]

Thank you so much for dedicating your time making these videos. They are so informative and helpful, and it honestly feels great knowing that if there is not a science concept I understand in school, there is usally a video here to help me out!!!

[@HamnaAzhar7]

appslover1232123212 he literally never disappoints!! Whenever i find a topic difficult, i come to Khan Academy and the problem is solved :)

[@CasieLeanne]

For an auditory learner this really helped me understand Glycolysis more, Thankyou.

[@jajafelipe19]

great reviewer for midterms in biology. no need for rereading notes.

[@ccoott]

Kahn academy basically taught my entire grade 12 year.

[@seni701]

Khan you are my hero im addicted to ur videos i love the may u teach guess what i got A+ for my immunology exam i love you and thank you million times pls do not stop to teach us : - ))

[@attiya5471]

Hey, I was just wondering, I mean if you wanna share where are you in life Now?

[@JoeyBagADonuts8]

the addition of ATP. One Phosphate is added onto the glucose and one on the fructose during investment stage. One P from each ATP since 2 are used in investment

[@SlyPolanie313]

This video can and will make you understand Glycolysis. Thank you very much

[@MrMattthemanc]

@MJfullofGrace - The anwer ro that question is that the first part of glycolysis uses 2ATP (breaking down glucose 6 carbon molecule to 2 3-carbon molecules ( intermediates which are then converted in a multistep process to pyruvate and for each pyruvate formed ATPS are produced. Therefore ther is a gain of 2ATP molecules. Body is constantly producing ATP don't think of it in isolation, think of body as many processes interconnected to produce energy to survive.

[@charlieisabeast100]

There are 4 phases - After Glycolysis is the link reaction (the conversion of the pyruvate molecule into CO2 and a 2-carbon molecule called Acetylcoenzyme A). This is vital information as in the 'Krebs cycle': this enzyme is introduced into a cycle of oxidation and reduction reactions that yeild some Atp and a large no. of e- for use in the e- transport chain (to synthesise ATP with water as a bi-product). Oh and do not forget to mention that it is phosphorylated glucose that splits into ...

[@PotionsMaster007]

omg i might actually pass my medical biochemistry exam, we get a cheat sheet so YES!!!

[@jesussosa3238]

Did you know that cheating is Academic Dishonesty XD JK!!!

[@strongbodystrongmiind]

Jesus Sosa lol

[@rachelcarney8976]

can't relate

[@schrodingerscat1556]

What happened man??? Did u graduate yet. I find it really interesting to reply to older comments

[@PotionsMaster007]

@@schrodingerscat1556 lol yea I passed and went on to get 2 more degrees lol

[@SapporoMagokoro]

Watched this video high IT ALL MAKES SENSE AND IS SO INTERESTING

[@jigglybandit]

Actually, contrary to your explanation, the loss of a hydrogen is not reduction, but Oxidation. However, overall nice job, I'm having a test on this in my freshman bio honors class tomorrow and it helped.

[@Wandering.Studios.]

Words cannot describe how thankful I am for your videos, specifically the cell energy ones.

[@Miauwmiauws]

He makes me feel that I understand it, unlike the classes I follow. Thank you!

[@Alexiaden93]

Actually never mind, the reason why you end up with 4 ATP is because you split the fructose 1,6-bisphosphate into two parts, both ending up as pyruvate. In each of these reaction chains you get out 2 ATP, meaning you have 4 in total. You invested 2 in the first part of the chain, so you have a net gain of 4-2=2 ATP.

[@luisaceo00]

nice video, but you forgot to say, when explaining the diagram at the end that the two PGAL molecules are added an extra phosphate group in order to produce 4 ATPs instead of only 2.

[@awanturka]

I actually believe that I can pass biochemistry exam :) you are golden! :D thank you so much!!!!!!!!!!!!!

[@metabog]

One of the best channels on KZbin, hands down. Thanks, and respect!

[@swordguilds]

@spicame I'm not sure about your first question but for your second question (I assume from 2-phosphoglycerate to PEP), the OH group on the terminal carbon has to leave to form a double bond with carbon 2 but at this point carbon 2 has 5 bonds and rather than breaking the chain or releasing its ~O-Pi, it releases the hydrogen. So water is released.

[@FirehorseCreative]

He forgot the 'u' in 'Pyruvate' as well- but it doesn't matter- he had me at 'phosphoglyceraldehyde' lol. What wonderful tutorials.

[@SabinaLovee]

thank you so much! i have a bio test tomorrow. you should come teach at my school!!!

[@MrEnriqueag]

This video has a mistake: The glucose produces fructobyphophate by adding 1 P from the ATP and changing the functional group to a cetose, when the fructobyphophate breaks down it produces a giceraldehyde and another 3-Carbon molecule, only that carbon molecule uses a NAD+ to produce a NADH and turn itself in another giceraldehyde. Only one NADH is produced Sorry for my english I'm Spanish

[@akshta10145]

This man is my life saver. Thank you!

[@FaerieDust]

I just have to say, thank you for these videos! I can't even begin to explain how helpful this is - all of your videos, really. I learn so much, everything's so amazingly pedagogical, you're awesome!

[@uvinp]

I have watched few videos of Khanacademy. some are amazing. but this one is not so much. It's 1glucose + 2 ATPs + 2NADs + 2 Phosphates ---> 4 ATPs + 2 NADHs + 2 Pyruvates. thnx.

[@지지님-k3b]

He has like the most helpful videos on cellular respiration thing

[@3squareddesigns]

Thank you, you are such a better teacher than my college professor!

[@Nytrox3000]

The phase you call "pay off" is called the oxidation stage. the one before is photophorylation.

[@Jasminaa011]

I learned more here than I ever did with my teacher :'] I love you Sal.

[@madcrazii88]

youre my new bio teacher. thank you.

[@lifeDotGov]

good job, but one correction.. you're adding 2 hydrogens(not 1) to reduce nad+ to nadh.. because a byproduct of nadh is h+ ion, which gets sent to the cytolplasm.

[@Penicillin1928]

OMG, the best tutor I ever had!

[@Samyrad]

During cellular respiration, it's the first step. It gets everything going

[@CraftyPirateJim]

Revising for my biochem resit exam, this is brilliant, why didn't I know about this before?!

[@pizzachew]

@MrEnriqueag Glycolysisis works with two pyruvates derived from a single glucose molecule. An NAD is reduced into an NADH for each of these, therefore we have two NADHs as products.

[@SkyN1nja]

@123123TheEmily The reduced NAD donate the electrons of the hydrogen atoms they are carrying to the first molecule in the electron transport chain. :) the reduced NAD is basically used in the ETC if you havnt studied it, it answers your question in detail and it will all make sense. Remember glycolysis is just 1 stage of cellular respiration. Hope that helped :D

[@megantran19]

I like the white background :] it's a nice change from the black haha a lot brighter and happier!

[@syaoranhien]

NAD Molecules originally come from B3 vitamin (sometimes called niacin or niacinamid) which is available in the Cytoplasm where Glycolysis occurs and PGAL did not produce NAD , NAD came from the Cytoplasm of the cell And .... that's it :D

[@PrettiUkhti]

im very happy i found your videos. you explain the topic so that i can understand how everything works.very very good!!!

[@sheilay98160]

This helps SO much! Thank you!! I think I'm ready for my quiz tomorrow now! (hopefully)

[@geegi163]

you saved my life and GPA!

[@chaseyoung1800]

kinda surprised me, the color of the background. but hey, im not complaining. you are GREAT man.

[@Happy1993Life]

2ATP are required for break the glucose to 2- three carbon . after break it 2ATP will convert to 2ADP .This is the first step of glycolysis

[@silverstars7]

the electron transport chain does not actually produce ATP. oxidative phosphorylation (the very last step in cellular respiration and separate from electron transport chain) produces the bulk of ATP through H+ moving in through the ATP synthase and ADP+P using that energy to form ATP.

[@Cypfer]

As you see, the PGAL has a Phosphate group which with the ADP forms ATP. ADP + Pi = ATP Pyruvate has no Pi groups anymore.

[@omgxd4]

Thank you very much! Much more understandable than the week of classes my teacher spent on this SMH. Well at least now I get it!

[@AznXRice89]

omg thank you soo much!!!! now I understand..your way better than my boring physiology teacher haha

[@jamesmay1164]

@Grace Niamh Lactate IS produced during anaerobic respiration, correct, but this was showing neither aerobic or anaerobic respiration. This was demonstrating the process of glycolysis. The first phase in BOTH aerobic or anaerobic respiration.

[@jonnytown12]

You sir are the man!!! You are simply a life saver

[@vXSuperSonic]

its crazy seeing he made all these vids 5 years ago and people r still watching as if he just realised the vids!! :)

[@TrevinAvery]

Most people group this step with the Krebs Cycle because it happens inside the mitochondria. He mentions it in his next video, "Krebs / Citric Acid Cycle."

[@kelseyblankenheim4134]

This video helped me understand glycolysis a lot better. Thank You!

[@270103023]

wow ! super helpful! much better than the 3D video! thanks a lot!

[@Mareikimi]

Thank you sooooooooo much, this is really, really helpful. Don't know what I would do without all the videos!

[@sydney3685]

Currently watching this the morning of a quiz I had a week to study for

[@danebell1]

i like his hand writing. this was helpful.

[@Kampenberg]

@MJfullofGrace ATP is readily available in the cytosol where glycolysis takes place. The average human stores about 80 to 100 grams (3.0 oz) of ATP under normal resting conditions.