Steps of glycolysis | Cellular respiration | Biology | Khan Academy

[@sccm100]

Why do I feel like the more science you know, the more you realize the less you know.

[@onetwoBias]

It's a bit like if you inflate a balloon, the volume represents your knowledge, the surface area represents the things your discover that you don't know. I guess it's just that you first have to understand the basic concepts of something to realize how much there is to know about it and until you do, all of that doesn't exist to you.

[@cosminbarbos4235]

Kant has a theory about this. the more you know you are pushing your knowledge limitations further and you realize how little it represents.

[@fizzakhalid3705]

hahaha! same man!

[@nikitakutakov1184]

"As for me, all I know is that I know nothing" Socrates used to say. Humans are always the same:)

[@TheCassholeJo]

That means your learning and your way of thinking has been advised by several of my professors

[@MrBones-bn7oo]

‘mind wanders for 5 seconds’ welp time to go back 3 minutes

[@deadmanperipherals]

facts

[@archstrider3509]

That’s so true

[@adelasefora]

so true!

[@gg025]

story of my life

[@Colombianaaa07]

Seriously smh

[@TurulHEMA]

Cool. Now if I watch this 10 more times I might have it memorized. . . Maybe.

[@onetwoBias]

Write it down from memory instead - much more efficient

[@lisab2631]

Wow so fast?! (not even ironic)

[@adelasefora]

literally same

[@TrapHut]

@@onetwoBias I agree!

[@mek2367]

Maybe checkout a less detailed one? It's rly not tht complicated

[@languageandmana9255]

Thank you for making FREE videos for PREMED students. Many intelligent students can't afford MCAT prep packages and even basic books! So you are doing a huge favor to them by making detailed videos on MCAT topics. All of the poor students are future doctors and they will be donating regularly to this amazing channel ❤ I wish a free medical school will be established one day just like Khan Academy, professional, kind and generous, in which people can study doctor of medicine for free.✨

[@earth6738]

Kahn puts my $100 biology textbook to shame. He's straight up out here slaying the science game. Thanks, Kahn.

[@mohamedmotaz5194]

Atleast spell his name right...

[@gboy05]

@@mohamedmotaz5194 he clearly khant

[@eemiaa10]

I have to memorize this for Tuesday. Lord help me.

[@nicholasevans9490]

May God help you.

[@shkoata366]

how did u do?

[@eemiaa10]

shko ata well I had Glycolysis down, but the rest of the exam was the beggining of my demise

[@queenjazmyne]

i need to learn al of this for this tuesday ha. Apparently tuesday is test day

[@priscillacastro775]

Aimee I have to memorize this for tomorrow...

[@asmahaque8558]

Stop sounding so excited, we hate glycolysis.

[@ThingsUShouldLike]

Lmao true

[@fadeskywards1245]

ahhahahahahaha This one takes the cake

[@StreetDancer171]

Nah, I enjoy learning about it, it's interesting to know what's going on in our bodies

[@madhurajoshi3479]

WaveDancer171 you do...And that's great! This is just the silly opinion of 90 percent of the people studying glycolysis..😑

[@hashirrasheedhaider6508]

WaveDancer171 you will hate it once you will see this in order to memorize it.

[@leeschloss4840]

If my body was able to take my biology test for me, I would've totally aced it.

[@aquariansage1451]

Even if this man was speaking in Navajo, my current level of understanding would still be the same.

[@caseylydon209]

Aquarian Sage retweet

[@anahiti2981]

that is literally me 2 years later. funniest thing i read all day..

[@Studley_Nilson]

🤣🤣

[@theobalatel34]

you know it that well?

[@visneliturta0502]

Great video, however one simple mistake: Kinases don't "dephosphorylate" molecules under physiological conditions. Enzymes for dephosphorylation reactions are called "phosphatases". The reason why the "pyruvate kinase" is called kinase is that while these metabolic reactions were being discovered, scientists tried out these reactions in vitro to see what the enzymes do and they put too much pyruvate and so turned the reaction balance in favour of phospoenolpyruvate (PEP) as product, so they thought, the enzyme phosphorylated pyruvate. But in reality, under physiological concentrations, the enzyme actually "dephosphorylates" PEP.

[@kingofgames9154]

Thank you for this nice information 👍 It can be crucial detail.

[@linkh1435]

I will always love biology the most. Chemistry, well, not so much. I mean it's quite an interesting subject but it makes me struggle so much at school. Same for Physics.

[@jquizo8530]

Weeeell, we have this topic for biology and I now only understand it more in Khan Academy than my Bio teacher.

[@tomato-v8x]

@@anshikasrivastava3951 Being indian has absolutely nothing to do with that

[@NikNikNiken]

Gosh this guys you'll be a voice actor; he's got such a soothing and calming voice ^_^

[@madhurajoshi3479]

Sloth no offence but to me he sounded really excited which was kind of annoying since I was breaking my brainpan to try make sense out of glycolysis....

[@madisonjoe1911]

3:13 is aCtUaLLy litEraLly the epitome of expectation vs reality and I died

[@marleyoo]

best comment

[@sumaiyazainab6986]

i cant stop laughing !!!

[@DJ.Harsh_Chopra]

😭so tough for a class 10 student like me

[@reemaalsweed6748]

90% of the video: we talked about this in another video 10% of the video: actually explaining glycolysis

[@shyamsharma530]

Wish the number of your comment's likes add to your IQ

[@JoudAlgorain48930]

realll🤣

[@apolloex00]

Why is life so complicated!?

[@mjeadeissa2980]

Creativity of god

[@Epopoi27]

Yet another equation : law_of_physics x random x huge_amount_of_time x selection = complexity of life

[@PhantomAyz]

Cuz complexity makes life awesome

[@thomasalberto613]

the double meaning...👍

[@shubhangnisharma6597]

Coz we r science students✌

[@lisagonzalez2902]

Thanks SO much, for all the videos you provide... It's helped me a lot throughout my medical career in the Dominican Republic. I finished it, and will graduate soon. Right now, I'm studying for the USMLE and reviewing quite a bunch of knowledge gaps! I don't agree with the comments on how his speech is too excited or whatever. Precisely, that's what makes me NOT fall asleep or get bored, since the way he talks makes everything much more interesting.

[@rosy5565]

You just made me understand the cycle in 12 mins that my teacher couldn’t in a 2 hours lecture. Thank you so much for putting this out for FREE

[@Mugen_YG]

I look away for 20 seconds and next thing you know, I'm as lost as a 3 year old in walmart by how much stuff you just put on the screen Sigh, that's biology for you

[@ezioblazesit9017]

This man knows everything, only rival to Johnny Sins himself.

[@shay3242]

I can's appreciate the complexity when I need to know all of this for a test lol

[@yassminmaher4997]

i studied glycolysis for nearly 4 years and only that video makes me understand it

[@JunZDK]

You really made it so much easier to understand. Thank you!

[@davidadams255]

MCAT is in one month. This is a life saver. Thank you!

[@emeka3033]

howd u do

[@davidadams255]

@@emeka3033 92 percentile! Thank you again!

[@emeka3033]

@@davidadams255 you legend, I’m studying for my first test in mid august

[@davidadams255]

@@emeka3033 best of luck my friend...make sure you work hard and make every moment of studying count. Perhaps even more important, make sure you give yourself time every week to rest and reward yourself for your hard work. Best of luck to you

[@BereketMinisha]

wow! BRILLIANT!,I am from Ethiopia East Africa and I love learning from your video!

[@monaipsm]

THIS IS THE BEST VIDEO ON GLYCOLYSIS EVER! Please do one like this on kreb cycle please!!!

[@StreetDancer171]

Dope video, I love how you actually enjoy what you're talking about and are enthusiastic about it!

[@maturename9817]

hey, Mr. khan, Id really appreciate it if you could include printable versions of the notes that you write in the videos as a link in the video description.

[@omarelhousseiny6155]

Last 2 seconds of the video: "Actually makes sense" (JAW DROPS)👍

[@FavouredElm2]

thanks to this academy, my grades aren't dropping like hell. love this channel

[@dannyawesome63]

You just explained what my biochem professor has been trying to explain for the past 2 weeks. (and drastically failing at it) Thanks!!

[@Autumnpaige19]

DannyAwesome63 A professor had to explain this in bio chem?! Wow I am learning this in general biology. Makes me less afraid of biochemistry now!

[@earth6738]

I had to walk out of my biology lecture and just look this process up on Kahn Academy because there was no way I was going to absorb any information with the way she was teaching it.

[@nicoletaylor1497]

@@Autumnpaige19 Biochem, you learn the mechanisms and reproduce them.

[@crystalkan4862]

my teacher explained this in a way that is hard to understand, and i am soooo happy this channel exist

[@czarina-q4i]

me: finished the video Also me: and that's why i hate sugar.

[@tquathlouis2521]

This is what I need for the exam next week 😌😌 Thanks God you are here Khan

[@sirian3092]

This video helps me a lot to understand the glycolysis process. Thanks!

[@shyamraiyani6954]

Superb explanation 👌👌👌🙏🙏🙏

[@xdaebakxab6344]

thank you so much for this vid! helped me so much! my biochem professor is clearly failing at explaining

[@MiamiCubanbcn]

In what Universe would anyone consider disliking this video. Thanks you 🙏🏻

[@Leah-ep3wh]

Had to memorize all the anabolic and catabolic processes for my upcoming test next week. Please bless my soul.

[@charlottedelaet5430]

I always watch your videos if I need to study something or I need to teach it’s so well explained!

[@Myleanne14]

Great video, thanks for mentioning all the enzymes involved

[@alshorty85]

Borrowing your brain to take the exams sounds better than this lol

[@shaniw.4728]

i thought i was the only one who thought like that

[@madhurajoshi3479]

Shani Williams I know right!!!

[@normiel7135]

Lol bet they graduated by now

[@theblimo4747]

Wow... I just began bio 20 and I’m already hooked on this, but I really should’ve taken Chem first!

[@arman8543]

Thank you that was very helpful for me 🙏❤

[@dina6177]

“this over here was replaced with that over there”

[@pouyaejtemaeimehr9352]

Thank you so much. A wonderful review for SAT subject test for which I am preparing even though College Board requires me to know much less about Glycolysis than what this video taught me.

[@lili-cl1zx]

great video, glad to know i can always come here for science help! :D

[@Itsme-rn1zb]

Ur talking style and ur voice make me listen u again and again.. 😅😍

[@michellegeorge1853]

Amazing video. Very very helpful! Thank you Khan Academy!

[@tinashechidzambga5422]

Thanks a bunch mate. That is exactly what I needed.

[@elissar2004]

The best! Thank you so much!!

[@gabrielqin9687]

Triosephosphate isomerase (TPI) is a perfect enzyme that catalyzes dihydrooxyacetone phosphate into 3-phosphoglyceric acid. There is an enol middle metabolite between these two steps. But this enol middle metabolite is easy to release phosphate group and become to malonaldehyde in a neutral cellular environment. The significance of TPI enzyme lies in that it has approximately 10 aa residues forming a loop that is designed to cover the enol middle metabolite preventing its release. In the end, as long as 3-phosphoglyceric acid is produced, this loop or cover will leave and let 3-phosphoglyceric acid go and do next reaction into 1,3- diphosphoglyceric acid.

[@hillaryherrera2125]

"3 cahhh bunn molecule" at 0:26 couldn't stop laughing at that part lol

[@gtarules1]

It only took him 6 years to post the video. lol

[@lamimkader8823]

itd be nice to have the whole page in one shot, so i could follow the reaction process

[@billcheney856]

just for the record, the two kinase enzymes in steps 1 and 2 transfer a phosphoryl group, NOT a phosphate. It seems like splitting hairs, but it's important to account for the oxygen atom.

[@ghulammustafamemon3382]

This is really appreciated. This one is the best one 😍

[@halaabdullah4168]

Thank you very much you make my life easier !

[@gayathrymuthumani9946]

Really helpful.. Thanks alot and much appreciated

[@juliam2070]

literally helped me SOOOOO******* MUCH thank you Khan!!!!!!!!!!!!!!!

[@infiredpumpkins1970]

Khan academy is a life saver

[@ouiemfrs4373]

I love you man come and teach in my University,:")

[@foxy9403]

you need to start putting adds on the videos my man.. they are so good.

[@ferrariluther5910]

majestirial,world class,sensational,brilliant,astonishing,intimate,definitive,point-wise.......

[@mrsquidward9454]

Omg thank you so much this really helped me for my freshman bio class

[@alyssaalcantara6739]

I think it’s cruel that the A.P. Bio, 12u bio curriculum requires us to memorize the steps of glycolysis. Although, I do appreciate the complex process that allows us to break down sugar from food and convert into the universal energy currency, ATP.

[@rubi22teresa]

Thanks 🤩🤩🤩🤩

[@acmb364]

To make it a bit more complex you could have drawn it in spiral instead of in circle. No, but seriously, thanks for the explanation! Very helpful.

[@stephenstralka6391]

I real appreciate this video. Helps too much

[@Nidacolada]

Haha, gotta love the excitement :D Thank you

[@JessicaMonterrubio]

No matter how many times I watch this I still don't get it lol Lord be with me I have a test Wednesday

[@jenetkolaparan7355]

Hey girl! I found you here lol. No worries we are on the same boat.

[@JessicaMonterrubio]

Jenet Kolaparan lmao

[@khaleesi.1737]

Have to freakin memorize this for report tomorrow. Wish me luck guys😭

[@mickey9554]

How was it? Gosh Amma report this next week help me

[@chezlise.holisticbeautyhea2012]

This is GREAT!!! Thank you!

[@linzhuo3099]

Hi there, In the graph you drew, you only have 5 hydrogens for glyceraldehyde 3 phosphate. However, the formulate for this molecule is C3H7O6P. Just a little confused with why there are 2 missing hydrogen. Thank you so much

[@farouk98kh]

the phosphate is with or withour hydrogen atoms, since it reacts with water in an equilibrium reaction. He chose to draw it without the hydrogen; yet, we can still put the phosphate with the ti hydroxyles

[@blinbin8415]

crying in the club rn my teacher didnt even teach us she gave us a ppt and some hw ffs

[@thepunlady3036]

teacher moved test to tmrw. panicking. no time. bye

[@Vic661]

How’d it go

[@Birthold]

The people demand answers

[@eden5695]

thank you for the vidya, you got a fire voice

[@briemarie8609]

This helped me so much, thank you.

[@SupagalSimmi]

so much effort..😄 god bless u

[@jbsilveradoo8788]

You guys should run a few ads but only before and after the video. It is very profitable, and it would ensure your survival as a channel. Ads before and after the video also wouldn't interfere with the learning process in the same way that ads in the middle of the video would.

[@Mehranamoments]

Awesome👍

[@marielabandero846]

Its our exam day and im watching , cramming is life

[@memcore1312]

And I thought intro to microbiology was going to be easy 😂

[@plusgaming3878]

Great video👍

[@shummu1458]

Now glycolysis sat in my mind😍

[@reemaalsweed6748]

I stooped the video in the middle to search “ how khan academy videos are made” and now finally i know and i can watch in peace

[@kkboligor7409]

tell me

[@xBlackShadowsZz]

7:16 Whoa, a lil rant there you went there khan xD

[@lamuse895]

Lord I just need to pass this class , and I will never heard of this again in my life

[@Ja-vx2nr]

Same dude I got a test in 2 hours

[@asha_4095]

@@Ja-vx2nr howd you do?

[@Ja-vx2nr]

@@asha_4095 Good enough

[@yort9173]

Bro that moment when he scrolled up at 3:19 , man I started freaking out. He said "more detailed" like it was no big deal. I'm scared. What's it going to be like later on then? DO I DRAW THESE IN THE FUTURE?

[@shyamsharma530]

It's better to admire the complexity than to fear it

[@rohanroy8504]

dis is d bst way to explain..... things got so much easier after watching d video ... always appreciated d work of khan academy😉...awesome-est

[@maheentahseen9039]

Lmao your voice literally made me excited when reaching the end😂 anyways, I always understand anything through your videos. Love em❤️

[@Pipita79]

You should do all the videos man,

[@SirreTV]

Nice video! Actually the enzyme hexokinase is accompanied by the enzyme glukokinase which works at higher glucose concentrations. Otherwise, pretty cool!

[@khushidogra4677]

Thnxs this is very helpful of my study

[@madaycampo5612]

12:00 --A kinase only phosphorylates. A PHOSPHOTASE dephosphorylates.

[@boristodorovic5735]

thanks a lot... u helped a lot

[@martinmitter5697]

In my chemistry book and other sources there is one hydrogen less on the final pyruvate molecule. You have a full COOH group there, which one is correct ? Pyruvate with COO- or COOH ?

[@lilyablitt7047]

that was great! thank you sm

[@bencmed]

I love you thank you for everything you do.

[@sparrowchinese1640]

I understand this cos I basically knew the topic, and would like to suggest maybe a more simplified explanation will suffice, cos it feels quite heavy when he explains...🤔😂 idk😐 anybody feels the same way?🤔😅

[@bestfanever2011]

Love the suddenly British Sal at 0:26