Lamotrigine (Lamictal): A complete overview of what you need to know

In this video, we discuss the mood-stabilizing medication, lamotrigine (Lamictal). This medication is an anticonvulsant that is used to treat Bipolar depression and maintenance. In this overview of lamotrigine (Lamictal), we will discuss what lamotrigine (Lamictal) is, what lamotrigine is used for, how long it takes for it to work, is lamotrigine addicting, the side effects of lamotrigine, the drug interactions associated with lamotrigine and lastly, my final thoughts on lamotrigine.
Intro 00:00
What is lamotrigine (Lamictal) 00:48
What is lamotrigine (Lamictal) used for 01:33
How long does it take lamotrigine (Lamictal) to work? 02:21
Is lamotrigine (Lamictal) addicting? 03:40
Side effects of lamotrigine (Lamictal) 04:29
Drug interactions with lamotrigine (Lamictal) 08:09
Final thoughts on lamotrigine (Lamictal) 10:29
Resources:
Deprescribing Guide: amzn.to/4dZEUMk
Stahl's Prescribing Guide: amzn.to/3UXj8QL
🎥 This video was edited by:
Rahul Kanchi / rahulkanchi24
🚑 If you are in a mental health crisis, please dial 9-8-8 from the U.S. Or text HOME to 741741 and connect to a crisis counselor.
You can find a list of international crisis lines here: blog.opencounseling.com/suici...
References:
Hashimoto Y, Kotake K, Watanabe N, Fujiwara T, Sakamoto S. Lamotrigine in the maintenance treatment of bipolar disorder. Cochrane Database Syst Rev. 2021 Sep 15;9(9):CD013575. doi: 10.1002/14651858.CD013575.pub2. PMID: 34523118; PMCID: PMC8440301.
Lamotrigine (Lamictal) (2015). FDA Label. Retrieved from www.accessdata.fda.gov/drugsa...
Stahl, S. M., Grady, M. M., & Muntner, N. (2021). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications. Cambridge University Press.
Stahl,S. (2017). Stahl’s Essential Psychopharmacology: Prescriber’s Guide, 6th Ed. Cambridge University Press.
Yatham LN, Kennedy SH, Parikh SV, Schaffer A, Bond DJ, Frey BN, Sharma V, Goldstein BI, Rej S, Beaulieu S, Alda M, MacQueen G, Milev RV, Ravindran A, O'Donovan C, McIntosh D, Lam RW, Vazquez G, Kapczinski F, McIntyre RS, Kozicky J, Kanba S, Lafer B, Suppes T, Calabrese JR, Vieta E, Malhi G, Post RM, Berk M. Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder. Bipolar Disord. 2018 Mar;20(2):97-170. doi: 10.1111/bdi.12609. Epub 2018 Mar 14. PMID: 29536616; PMCID: PMC5947163.
Disclaimer: All of the information on this channel is for educational purposes only and not intended to be specific/personal medical advice or substitute for diagnosis and treatment of any conditions discussed herein. Furthermore, watching these videos or getting answers to comments/questions, does not establish a provider-patient relationship. Please consult with your own health care provider for proper diagnosis and treatment.

[@LevelheadedMind]

www.levelheadedmind.com/contact Need help with your mental health treatment plan? Contact me so we can discuss treatment options best suited for your unique needs.

[@VioletFoxisms]

I take it for bipolar 2. I never knew what stable moods felt like. I’ve never felt so calm. I love it!

[@johnb7499]

I'm prescribed it for bipolar 2 as well and it's the only medication that has ever worked

[@finity9316]

What has it helped you guys with ? Has it helped with motivation, anxiety brain fog ?

[@johnb7499]

@@finity9316 yes motivation, brain fog, overall mood. I use to have 4 day episodes where I was too depressed to get out of bed. No longer happens.

[@johnb7499]

@@finity9316 I'll also say I was on all different kinds of SSRI's and SNRI's for almost a decade with no relief from my depression.

[@finity9316]

@@johnb7499 damn I hope I get the same result, what about your speech and talking in a conversation ?

[@megangallaher4011]

I’ve recently cross tapered from an antidepressant to lamotrigine and finally feel like I’m feeling that I can recover and thrive in life despite mental illness. I had been misdiagnosed for over a decade. I’m so grateful to be finally seeing the light.

[@williamfoley5687]

I'm 66 and just started Lamictal.Been severely depressed since 1977 when my younger brother Stephen was killed on his bike.He was 6,I was 20.Thanks for info.Jesus loves you.

[@RedeemedbyKingJesus]

JESUS LOVES YOU!!!!!

[@raykingtv2351]

JESUS LOVES YOU GUYS !

[@QuinnHarleyQuinn]

Jesus Loves You!!!

[@kerrimclaughlin9830]

Lamictal saved my life. I've been on 400 mg daily for about 7 years (along with 150mg of zoloft) after a suicide attempt, hospitalization, and numerous medications for depression/anxiety/ADD that didn't work. I very slowly increased the dosage under my psychiatrists supervision and have not experienced any side effects, this medication was seriously a life saver for me. I didn't think there was any way to continue with life feeling the way I had been feeling, but lamictal was the light at the end of the tunnel. This was a very informative video, thank you for the education!

[@LevelheadedMind]

I'm glad to hear you found something that is working well for you.

[@rdettwyler]

I'm on 400mg, paired with gabapentin (chronic pain).

[@kristij4733]

I’m On lamictal 200mg for BPD mood stabilizer. I have had no side effects at all. No more manic episodes, no more flipping out or irritable anger issues. It hasn’t helped with my depression, but it really keeps me level instead of up and down. No more feeling unstable. Really helpful for me

[@Lisabug2659]

The 20-40mg of Prozac in combination makes a difference. With the magnesium, glutathione, and DL Phenylate, this is the first time in 2 decades I have felt normal and not ruled by GAD and depression. Lamictal and supplements was game changer.

[@kristij4733]

@@Lisabug2659 good to know! I’m On Effexor for depression, 5 years and I think it’s not working as it used to. I may see about trying that

[@Lisabug2659]

@@kristij4733 my psychiatrist started really paying attention in the past 18 months. Yes, Prozac does help with depression, yes, lamictal is a game changer on leveling moods and anxiety. The combination for me was extraordinarily beneficial. Added the supplements and magnesium….. there was a breakthrough I can’t articulate -- now I take a very low Prozac…. 40mg every other day with 200 mg lamictal. I experienced a traumatic brain injury over 20 years ago…..I am successful, high functioning but ‘normal” and level is a new experience.

[@roxywyndham]

Stop I’m crying because my anger from BPD is my biggest concern. I’m starting today. Wish me luck 😭.

[@milanic7267]

​@@roxywyndhamHi. I have bpd, I feel terrible rage and anger. Did lamictal help you? Thanx

[@Michaelgoestofrance]

I was diagnosed as somewhere between cyclothemic and bipolar II. I was literally out of control. My psychiatrist tried me on a massive range of drugs but none of them brought me relief or were sustainable because of their side effects. Then one day he said "have we tried Lamictal?", I said no and so he prescribed me the drug. He really didn't follow the protocols for titration but fortunately I had no side effects. I have now been on the drug for over 10 years and can safely say I've never felt so stable. I actually do still get some ups and mainly downs (for which I'm on Prozac) but I don't feel "drugged" by Lamictal. I feel, most of the time, kind of 'just right'. I have to admit, sometimes I miss my hypomania, but I certainly don't miss the crippling and extremely dangerous lows I used to suffer with. I'm on 400mg a day and, unlike some of my other meds (I'm on a lot!) I don't feel any need or desire to stop taking the drug. It really changed my life.

[@briandavenport8971]

More helpful than my prescribing doctor.

[@jazzym5873]

I take it for epilepsy and borderline personality disorder and it has been like night and day! I feel stable and my emotions are drastically less intense. It’s absolutely amazing

[@oz7916]

I take it for seizures as well. So far the best for me. Also I’m on clonozepam which I’m weaning of slowly under my neurologist supervision

[@AlanAssuncao08]

What I'm about to say is probably a little too early. My doctor prescribed this medication for my case of anxiety and constant mental racing. I've been using it for a week and I can say that I feel fabulous. This medicine simply made all the symptoms I felt disappear and made me see everything in a natural and calm way. I didn't have any side effects.

[@mariomello3495]

How are you doing today?

[@krillr_prawn]

I was prescribed this for OCD and had the worst time. My vestibular system was thrown out the window- unable to balance. Extreme blurred vision. Made my intrusive thoughts harder to deal with. Then I was introduced to Dexamphetamine for ADHD and Prozac for Depression (not MDD) and Anxiety (GAD/SAD) and my body was so confused, with all three meds simultaneously. Obviously has helped other people, I think in my case Lamotrigine was carelessly prescribed and not appropriate for my presenting conditions. Immediately felt better coming off Lamotrigine.

[@gustavosaggese899]

Lamotrigine has changed my life. I do have a couple of side effects (photophobia and slight insomnia sometimes) but it's totally worth it. And I still have bad days but the intensity and length of my mood changes has been drastically reduced.

[@MsSmokeNmirrors]

This helped a lot with my depression and somewhat with anxiety.

[@AmberLeighD]

Lamictal saved my life.

[@noelcordero9107]

Excellent video. She's detailed and explains in a fun way.

[@willn1395]

You present the information clearly and effectively and are a kind and caring person. Thankyou

[@sunshinelavender1663]

Thank you for content. I finally agreed to see a psychiatrist as well as my therapist and try pharmaceuticals. We finally found what worked and that was lamictal. I am so grateful for my doctors and proud of myself for finally getting help, but I feel like I’m not being heard with my concerns. Biggest issue being my eyesight. It’s rapidly getting worse and I had 20/20 before lamictal. Dr is adamant that it has nothing to do with medication. I’m standing my ground on 200mg and if he had it his way it would be much more. It’s just frustrating. I know this is what my brain needs to feel normal for the first time in my life, but I also want to trust the people providing it

[@goddessvibes2345]

Every doctor has said something different about lamotrigine concerning the side effects, other than the serious rash. ☹️ It leaves me feeling frustrated and having to do my own research. Interesting video

[@marybarrett2002]

Thank you for producing this video. Lamtical has been working for me for me many years.

[@LevelheadedMind]

You're welcome, thank you for watching our videos.

[@marybarrett2002]

@@LevelheadedMind 🌻❤️🌻❤️

[@jackchop1576]

This is the only mood stabilizer that prevents both mania and depression in the extreme. Lithium and depakote often make depression worse for me due to the "zombie" feeling.

[@gregorycarlson6632]

This is my first time on your channel and I will subscribe. My story is something that ties right in with this. I was diagnosed with severe Clinical Depression in 1990 and have battled it since. I have been on Amitrypiline and Cymbalta as well as Ambien for a good number of years now. Two years ago I suffered an abscess in my brain that was inoperable and resulted in a sizable infarction resulting in Focal Left Temporal Lobe Epilepsy. My Neurologist deals only with Epilepsy and other seizure disorders. I take 200 mg of Lamotrigine twice daily and my seizures are completely under control. I was not fully aware of the other uses of the drug. But I must say that it has not effected my psychiatric drugs either way. I can explode in temper, but that is strictly due to the Epilepsy because the Temporal Lobe of the brain is the seat of emotions. I learned a lot from this vid! 👍😊

[@LevelheadedMind]

Thanks for watching and for sharing your story. I hope it will help others in similar situations.

[@sophiethesnail]

i take lamotrigine in combination with some other drugs as mood stabilizers for my BPD. it has been so helpful so far. everything is just calmer.

[@ancabostinariu6550]

Very well presented. Congratulation.

[@deaunacawley2762]

I have dementia and seizures and mini strokes, high blood pressure low heart rate. This is why they have me on this medicine. I just started it. I wanted to learn about it. They had me on some other medicine but they wanted me to try another one to see if it helps my dementia. I’m in my early stage. I always research the medicines that the doctors put me on or what’s wrong with me.

[@LevelheadedMind]

I hope you find a treatment that works well for you.

[@WhatShouldMatter]

❤

[@vincea1594]

this medication saved my life

[@caro8712]

Best explanation on this, thanks.

[@LevelheadedMind]

Glad it was helpful!

[@jessgraham3700]

Helps me so much it’s saved my life I don’t shop impulsive I think before I do stuff

[@Yuppie.Mike.]

I was on this for ten. It causes liver damage. I was diagnosed with cirrhosis of the liver when I don't drink it also causes vertigo I went to the hospital by ambulance with what looked like Transit ischemic attacks for 8 years. Doctors had no clue what was causing my vertigo.I had an attack in front of my sister and she figured it out immediately. Don't ask what the possible side effects are. Ask Google does it cause liver damage does this cause vertigo. If you don't ask specific questions you only find out what the pharmaceutical companies want you to know. There also was a 3 billion dollar lawsuit it causes death in some people. You can look all this easy to prove. I quit taking it. my vertigo went away and I no longer have cirrhosis. Please ask Google specific questions about medications not what are the possible side effects you will not find the truth. I cannot believe my sister with no medical degree figured it out in five freaking minutes and I suffered for so long

[@kathymaeve]

Totally agree.

[@barbieknight6761]

Cirrhosis is permanent and cannot be reversed. The definition of cirrhosis is scarring of the liver. Once you’re diagnosed with cirrhosis, you cannot regenerate liver cells. Now, you can have non-alcoholic fatty liver disease and reverse it with specific supplements like NAC, choline, and milk thistle, and it will eventually turn to cirrhosis and becomes irreversible if not treated. When you take medications that are metabolized through the liver like that, it’s a good idea to also take NAC and milk thistle as well because they’re hepatoprotective, therefore they mitigate the liver injury caused by hepatotoxic agents (prevent damage to the liver). This medication is the only one that has ever worked for me without making me feel detached, numb, and weird. It’s really about doing your research and taking things properly, like in this case where there are things you can do to minimize potential risk while benefiting from the medication, improving overall quality of life.

[@mrduckman3150]

ive been on this for four years, helped pull me out of a terrible anxiety/panic state (i mean really bad) my symptoms have recently returned (i was only on 50mg a day) ive been on 100 now with little to no relief, just upped again to 125 (scared of pills so we are going slow). Hoping this guy works again, saved my life the first time around (no joke). Dr and Therapist both have said its super normal for a medication to eventually stop working and people need to up the dose. Good luck on everyone. Also wanted to notate that when i first started i had no side effects, but i also did Genesight which showed that i metabolize and my body works well with it.

[@addiegraves3]

How are feeling now? I'm in the same boat as you, I was just prescribed this treatment for severe depression& anxiety along side my regular antidepressant anti anxiety medication. I was so scared to try a new medication I called my Dr. Several times with questions. I just took my first pill I'm still a bit nervous about the possibility of rare side effects. From one Anxiety/depression suffer to another I sincerely hope you are feeling better ❤

[@mrduckman3150]

@@addiegraves3 I’m feeling somewhat better I’ve gone up super slow on the medication .

[@addiegraves3]

@@mrduckman3150 Thank you for replying, It's reassuring to hear good news, Mental illness can be some rough territory wishing you smooth sailing P.S Don't forget your not alone in the boat ❤

[@jamie1081]

I just started it. I’m prescribed 25mg per day, for one week, increasing by 25mg increments every week until 100mg. I’ve tried over 30 meds, I hope this helps me.

[@amayasteensma]

I really hope you can find one that works for you. Hang in there.

[@maryfrazier8493]

How is it going? I just started 25mg for bipolar2

[@ancabostinariu6550]

Very good info

[@stevensicherman4101]

I am seeing lots of positive comments here, lamotrigine being able to eliminate depression and anxiety. I need to get signed up

[@lawrencesaylol]

It’s truly a wonder drug. No side effects for me. And the best thing is I don’t “feel” anything. I just feel good.

[@elysemattocks1495]

I have a fabulous mental health team and this medication have been very helpful for me to low mood swings My dr and pharmacist were both very educational on the importance of the titration also ❤

[@asprelskcalling1151]

OMG, love this one❤

[@amayasteensma]

I am always afraid of bad side -effects and was told today by my hoosital that they want to put me on this after a blood tests and I am definetly willing. I have a history with earing disorders, so weight-neutral is definetly a pro for me, and I cannot currently afford a lithium shuffle and loss of creativity as intense as can happen with lithium given how I have just started my design master's. And I have not been in an accute state for some months now, so I don't have the urgency for medication effects as I did when they put me on olanzapin and quetiapin. Thank you so much for this information.

[@AlexisDoles]

For me - dry mouth, stomach pain - diarrhea, stiff neck, some dizziness - seriously messing with me as I just went from 50-100mg but on the real - the benefits I have had outweigh any of this so I just want to wait it out. I went through this when I first started and it sucked but when it stopped, I felt so much better

[@hoyconjessi5141]

Hi Dr, you have been very helpful with all your videos and have been so kind to also respond and I thank you for that . I just started my fist dose of 25mg of lamictal and have been taking klonopin at night for sleep and anxiety. My symptoms are intrusive thoughts, anxiety, I feel obsessed on how to fix my self and insomnia and have low mood due to all of it. I have tried everything from Ssri’s and snris but got nothing but horrible anxiety. My psychiatrist recommended this and I just hope it doesn’t mess with my sleep like the others medications did. I took it at 8pm how will I know what’s the best time to take it? Hope you can help.

[@pattykauth2431]

Lamictal is my friend. I have bipolar 2 and they tried me on lithium. It made me feel as though I had checked out. I was a walking zombie. They switched me to Lamictal and those symptoms went away!

[@BeccaG87]

I have tried an extensive list of antidepressants that caused side effects or emotional blunting. Recently prescribed lamictal for complex PTSD due to emotional dysregulation

[@michaelbassolino]

Thank you 🙏🏼

[@stevenbigbee1766]

Successful 4 many. But caution pay attention .. wkd for me for few years then litterally chemically changed my personality like an ongoing hypomania, bouncy, ur brain so unable to be aware of this, eventually led to mania episodes, my dr. Had me try higher dose and quickly decided to get off it. Back to no pharmas just luthium past 9 years fluidly perfect for myself. It is still the gold standard.

[@SmartCat...]

Hi Doctor! Thank you as always for such informative videos. I am wandering if you can make one more and compare the Abilify with Risperidone. My moms doctor wants to switch treatment from Citalopram (20MG)+ Abilify (2MG) to Citalopram (20MG)+Risperidone (0.5 MG). Thank you so much!

[@LevelheadedMind]

I have a video on Risperidone coming up in 2 weeks. I will add the comparison video to the list of videos. Thanks for watching and for sharing your idea.

[@PrincessKLS]

I recently got diagnosed wit Bipolar Type 2 and this is my first bipolar-friendly mood stabilizers. Typically anti depressants don't work for me. I either have Bipolar and MDD at once or my Bipolar was misdiagnosed as MDD in the first place. I just recently started the dose of 200 mg.

[@LevelheadedMind]

I wish you the best of luck with your treatment plan.

[@milanic7267]

Hi, is lamotrigine still helping you?

[@lizzee.r]

Can you talk about lamotrigine as a treatment for neuralgia?

[@babynaysc]

I started using Lamitor for Bipolar depression, they say it's very good, it's a medication that has to start with a low dose and increase slowly, I have to reach 200mg

[@MaraS-vm3fv]

I have taken it for my diagnosis since I was 17 years old with Bipolar type 1 , anxiety and PTSD with delay expression. With medication which I take would be depakote ER, Klonopin & Depakote XR . Which I actually was not doing well with Lamictal.

[@addiegraves3]

I was just prescribed this I've never been diagnosed with BPD. Is this a routine treatment for severe depression& anxiety when you're current SSRI medication is just not cutting it anymore?

[@endlessvoyageca7518]

Lamotragine is also used for SUNCT in slightly higher doses. It has been reported to impact memory in Epileptic patients. SUNCT patients also report memory issues

[@lasagamondays8440]

Do you advise patients to take their dose in the morning or at night?

[@jamie1081]

Do you think once a day dosing is fine? Or should it be given am and pm? If a patient was on 100mg max daily dose?

[@matthewrousseau2982]

How does It fair up as an "add on" to an ssri for treatment resistant unipolar depression?

[@madelrcardona]

What are your thoughts on Lamotrigine for Cyclothymia?

[@copyWRITEmyish]

I was just prescribed this today and I’m afraid simply because of the side effects like the seizures and that internal rash 😮😮

[@SS-1289]

I just started as well and so far I am struggling with terrible stomach pain, back pain. Insomnia and itchiness

[@mousynco]

Hi! I used to be really worried about those side effects too, especially the notorious rash. Please feel free to ask your provider or pharmacist for more information about potential risks, that's what they're there for! At least that's what helped soothe my anxiety around it, by having a deeper understanding of it. Informed consent is the best. This is part of the response from my provider when I anxiously messaged them about a missed dose: "There aren't any scary side effects from missing a single dose of lamotrigine. If you stop it for awhile (more than a few days), you're supposed to start again with a low dose to avoid getting a rash." I hope this helps and keep taking care of yourself. You're doing great. 💚

[@mousynco]

I realise I basically shared the same info as in the video but I hope you'll find more comfort over time in the treatment!

[@klausbohlert6613]

​@@SS-1289 Hallo ss,mit Rückenschmerzen habe ich auch zu kämpfen.Ich werde Lamotrigin wohl absetzen,oder noch niedriger dosieren müssen.Ich wünsche Dir, daß Du wieder gesund wirst.❤❤

[@groovyxyz]

i was at the 50/day supposed to go up thursday but they messed my my video appt and i havent been able to get in touch with the dr so i am out. i already feel like a zap feeling going on, hope it doesnt get worse

[@clintparsons3989]

This stuff is amazing. After 4 days it’s like someone flipped a switch. Zero side effects whatsoever on 200 mg/day.

[@LevelheadedMind]

Great to hear it is working well for you!

[@babynaysc]

Is Lamictal good for depression and mania too?

[@jackwilliams7738]

@@babynaysc it’s good for killing people. lamictal has already killed at least 15 Americans including a police officer from Texas. Perfectly healthy patients start taking lamictal and 4 weeks later they are dead.

[@jackwilliams7738]

Congrats on taking lamictal. Lamictal has already killed at least 15 Americans and hospitalized thousands. Lamictal is black labeled which means it’s one of the most dangerous medications in the US.

[@babynaysc]

@@jackwilliams7738 i dont believe that...

[@Deltanurse]

I experienced the photosensitivity and double vision, otherwise felt good on 300 mg. Using for seizure disorder was not effective for me, although After changing I see how much it helped my mood and focus ❤

[@milanic7267]

Doctor, can we take the whole dose in the evening instead of two doses, in the morning and in the evening?

[@isabellesmama10]

I take effexor and lamictal together to stablize my mood but I've never been diagnosed with bipolar, just major depression disorder. If I take an antidepressant without a mood stabilizer, it makes me more depressed. 🤔 Can someone be prescribed lamictal and not be bipolar?

[@mogotrevo]

I know they're rare side effects but yikes.. that's a long list of serious things that can happen.

[@babynaysc]

I'm bipolar, I used 200mg of Lamotrigine and the doctor asked to increase it to 300mg, I started 3 weeks ago and I have a headache and pain on the sides of my face, as if it were sinusitis, even taking pain medication, it doesn't relieve it much. Along with that, it ends up making me a little dizzy.

[@pamelawalton2417]

I was prescribed this med for mood disorder have been on this over two months i am feeling off balance when walking as well as some staggering i was on 200mg but lowered it to 100mg and still having these issues i feel tired all the time as well also i have CFS could you please tell me if this med sounds right for me. Thank you very much

[@KarolB244]

Can it work for major depression with no bipolar diagnosis. I've been prescribed this because antidepressants and antipsychotics have not work for my depression and depersonalization.

[@UnboundUnreal]

I stopped taking it after 4 years for mental problems. It was 200mg and it’s been a week. I feel tired and like I’m cognitively handicapped. I’m a smart guy, but now it feels hard to speak normally. Does this go away is this normal?

[@teshiamcginnis7923]

I was put on lamoctyl and after 10 days I got systemic reaction. I’m in the midst of it right now. I haven’t had a fever or blisters but the rash is everywhere on my body and keeps spreading. Doc gave me a cortisone shot and prednisone. How much longer will the itching and rash last? I was started on only 25mg.

[@mkz1840]

My friend has nocturnal epilepsy (I think it's considered as simple partial pr complex epilepsy, depending on whether he convusles or not). Anyway, his epilepsy is starting to show up during wakefulness. His carbamazpine seems a bit "overkill" for his case? Maybe?, so is it OK or "better" for him to be ob lamictal instead? Especially if he wants good cognitive performance for his college life; assuming carbamazapine might be too strong? Thank you 🙏

[@denisesarjant1912]

Didn't work for my fiance who has seizures, It made him very aggressive and couldn't walk a straight line. Neurologist took him off straight away.

[@stephens0077]

Dose any body know if there are any interactions with ashwagandha, vitamin D or spices. Thank you

[@peggylee6086]

I take it for an anti seizure medication . Does it only make a difference with mood for bi-polar disorder ?

[@stormy3078]

Too long didn’t watch but I hope she mentioned the black box warning for Steven’s Johnson’s Sydrome that this medication can cause

[@kranthikumarreddy6155]

hi please explain about Norepinephrine reuptake inhibitors

[@LevelheadedMind]

I have a video on Bupropion which is a norepinephrine and dopamine reputake inhibitor, but I can make a video about how NRIs work. Thanks for the idea.

[@KT-fm7dt]

Can you use this as mono therapy?

[@TheJeanettelmcgrath]

I'm curious to know the algorithm for bipolar depression dosing. Originally my psychiatrist said we could aim for between 200-400 mg. I noticed pretty early on (75 mg or so) that the physical aspects of my anxiety quieted but around the same time my recall memory (especially for names) became difficult. I really haven't noticed a difference in memory or anxiety quietening with the increased dosage. I also haven't noticed much difference in depression. So, I wonder how does a specialist determine whether going beyond 200 mg. is worthwhile.

[@LevelheadedMind]

Great question, there's no algorithm per se. It is based on treating your symptoms, if your primary symptom is depression and it is not being treated adequately, then that would suffice increasing the dose. Personally, I would hesitate going above 200mg unless there was some response first. Definitely worth a conversation with your provider.

[@TheJeanettelmcgrath]

@@LevelheadedMind thanks for your response. I'd say my primary symptoms are anxiety (social), C-PTSD and yes some depression. It has helped anxiety for sure, but help for depression is lagging.

[@JustinAdamsMD]

I’ve taken it since it was a branded drug. It has saved my life! Probably my husbands as well; I’ve not offed him yet 😂 Side note, I started it when they were making a Lamictal starter kit so it was super easy. I quickly went to 200mg BID (2x daily) Edited to add I started when I was diagnosed as bipolar type 2, then a full history was taken by a better psychiatrist who realized I was in fact type one bipolar. I had a manic episode at age 13 that was never diagnosed because “back then” we didn’t diagnose younger patients with bipolar disorder.

[@joecurtin2531]

My doctor just perscribed me with this but did not diagnose me with bipolar and only said I have an unspecified mood disorder. Is this a normal situation? I just picked up my first prescription today but am a little nervous since when I look this medication up all I see is stuff for BP or Epillepsiy which currently haven't been diagnosed with either...

[@sarahmcswan]

Man. My psychiatrist did blood work and said I wasn't at a therapeutic dose so she bumped me up from 300 MG to 400 mg!! I just had an appointment with my neurologist yesterday for my MS. He said it doesn't sound like that Doctor knows what she's taking about. 400 MG would be more of a therapeutic level for seizures, but not for BP 2. I'm looking for a new psychiatrist!! I noticed when I when I bumped up to 400 MG I was crying at the drop of a hat. It could be over something person all the way to a sad commercial or even thinking of something mildly sad

[@LevelheadedMind]

Yes, your neurologist is right. You don't use lamotrigine levels to guide treatment, you use the lowest dose that will treat the patient's symptoms. Typically this is anywhere between 100 to 200mg.

[@marthatsehaye8176]

Hey, my daughter has general epilepsy and they giving her lamactol 600ml. Is that the right medication for her?

[@dustin7405]

I was just prescribed this and I’m terrified of the rash because I’ve seen so many horror stories when researching it. Kinda just don’t want to take it 😭

[@1975KyleDavid]

I was prescribed Lamotrigine with Topirimate, roughly five or six years ago. I had taken the two for seven years, along with setraline. While I was on those prescriptions, my memory was foggy. I can say that I feel much better being off the prescriptions--though I might have a seizure or two per year--because my train of thought is clearer.

[@LevelheadedMind]

Topiramate is known to cause that brain fog as a side effect.

[@milanic7267]

​@@LevelheadedMindWhat is the diagnosis?

[@aternias]

definetly the Topamirate. personally when I was on it I was numb all over my body and felt super high

[@milanic7267]

@@aternias Topiramate over Lamictal?

[@LindaSaffioti]

Lamictal has decreased my memory big time. I’ve been on it for maybe 5y

[@karenconstantine334]

How do u feel my taking lamictal I’m not bi-polar, but have cptsd, chronic anxiety since I can remember , I started 5 days ago on 25mg , is it possible I can feel it so fast … and some depression which I I never really had? What’s up? Thank you Karen

[@AesthetimisticApproach]

I take it for major depressive illness with venlafaxine 150mg+lamotrigine 200mg For first 10 days my symptoms was good but now again my symptoms is rebound Should I increased lamotrigine or not

[@Abdaullahabdelrhman93]

what is the pregnancy category please?

[@simoroshka]

5 years on it and currently getting off. Totally not worth it for me. I seemed to have little to no side effects at first, but then on 200mg I developed a really bad depression, it was then reduced to 100mg, and the thing is it is not really working against my bipolar cycling that well. Instead, I noticed a continuous decline in my cognitive functions. It was slow enough that I did not ring the alarm for years, but the difference between me 5 years ago and now is staggering. Also, it can cause or make worse heart rhythm problems which is a huge no for me cause I already have problems - but no one told me about this. The withdrawal even with slow tapering is quite horrible too. Please research thoroughly and have a good talk with your doctor before starting it.

[@debbiemortinson]

Totally agree. Side effects are bad and dementia is real on this drug.. Just do a slow taper of about 5-10% reduction every 3-4 weeks. Really bad withdrawals, similar to benxos (both work on GABA).

[@anamariafernandezpabon822]

Hi! I agree 100% with you!!! I am epileptic and have been in Lamictal/Lamotrigine for 7 Years and l am loosing memory.... A medicine that will take you a surprise trip to having dementia..... *can't be a good medicine.*

[@wadeharris348]

Could you reach out to me? What’s it like tapering off?

[@emilyann4549]

I'm on it for epilepsy, but I hate it. My day to day mood is very bland. I'm an artist and didn't start having siezures until 3 years ago. They put me on lamotrigine because kepra alone wasn't totally working. Havnt been able to create like I used to. My creativity and focus has been severely stunted.

[@ashleyzeleznik5388]

I had increased liver enzymes while on 300 mg of Luvox and being on lamictal for about a week and a half. My doctor and I decided to drop the Luvox and restart the lamotrigine this past week. How likely do you think that the Luvox was causing the elevated liver enzymes and not the lamictal? Thanks for the video.

[@LevelheadedMind]

Luvox or fluvoxamine, is known to increase liver enzymes more so than lamotrigine, however, both could potentially increase them. So monitor blood levels in 3 months, if levels aren't trending down, reconsider other treatment options.

[@marybarrett2002]

You have a very kind and soothing way about you. I have a wonderful psychiatrist as well. I bet your patients love you and they are lucky to have you. Have an awesome day.🌻

[@sands-tp1ul]

Is this drug a fit for an adult who has a history of childhood epilepsy? Is there any evidence that this drug would reignite, so to speak, a past seizure disorder?

[@madelrcardona]

Does Lammotrigine generate apathy? Will I not feel excitement or euphoria in regular levels?

[@anthonymiller6081]

Can you take 50mg of Lamotrigine with 5HTP?

[@deepvoice4195]

Couple questions, I got prescribed with this because I told my doctor that I can’t stop thinking about this girl at work and sometimes it keeps me off task. I mean I do like her but it keeps me off task. And lastly what are the odds it could make you feel suicidal

[@LevelheadedMind]

Suicidal ideation is very low risk with a mood stabilizer. However, I am more concerned that you were prescribed medication versus offered or referred to therapy. Your symptoms don't sound like they require medication, let alone a mood stabilizer. It doesn't make sense, get a second opinion.

[@stevensicherman4101]

Enjoy your videos. Anxiety as a big part of bipolar 2 depression. Is lamictal effective for anxiety. Thanks

[@LevelheadedMind]

Yes, it can be helpful for anxiety as well.

[@stevensicherman4101]

Thank you

[@maryfrazier8493]

Has it helped your anxiety? I'm switching from Seroquel to Lamictal and just started. I have bipolar2

[@thegirlsguide007]

My doctor wants to have me on Lamictal in combination with either Xanax or Abilify after I stop taking my Depakote/Abilify combination to manage my Major Depressive Disorder. From your experience does Lamictal work well for MDD?

[@LevelheadedMind]

It can work well as an adjunct treatment, however, I'd stay away from Xanax, very bad long-term effects.

[@alexisloves182]

I just started on the lowest doses of lamictal and topamax. I feel worse. I feel like it exacerbated my mood swings. That or it’s not yet working. It’s only been 3 days 😅

[@KelzBernard]

The VA just sent me this in the mail. No thank you!😮Seizures as withdrawal??? No sirrrrr. I’m cool on Lamotrigine…✌🏽

[@coffeecat086]

I am taking 100/mg and so dizzy! Walking is so difficult to walking from the meds. I have a neuro appointment on 8th but this is so disruptive. Decreased dose to help with it, but tts not getting better.

[@LevelheadedMind]

I'm sorry to hear you are experiencing these side effects. I hope you and your neurologist can determine a treatment plan that will work out for you.

[@scordon731]

After two days of taking this I started getting SEVERE anger with murderous rage. It was BAD. I stopped taking it before I finished the orange cardboard trial pack.

[@helenalovelock1030]

What about the Mirena coil as birth control? With Lamotragine?

[@LevelheadedMind]

Mirena birth control is not affected by Lamotrigine and vice versa, it seems to be oral birth control containing estrogen that interferes.

[@helenalovelock1030]

@@LevelheadedMind Thankyou so much

[@mahsashalileh8601]

useful , thanks , would you help me plz : my dr told me to start Lamictal and gradually stop my Sertraline , I wanna know is it okey to use them together in 2 weeks ? is there any problem ?

[@LevelheadedMind]

Yes, typically they are used together without any issues. Discuss any concerns you have with your provider.

[@rebeccaeastham7693]

Help! I am suffering with recurrent UTI’s. They started shortly after I started taking lamictil one year ago. I have suffered with monthly UTIs ever since. What do I do!!!!?

[@LevelheadedMind]

Discuss with your health care provider. Have complete work up, labs, and renal function tests. You can also take cranberry extract routinely to help prevent them.

[@michelevanhulse9339]

Can it be used as an adjunct to anafranil for severe OCD?

[@LevelheadedMind]

I've never used it for that, I guess it would depend on the symptoms you are targeting.

[@milanic7267]

Hello! Can lamotrigine help chronic anxiety and restlessness in people with BPD?

[@LevelheadedMind]

It might. Talk with your provider about it.