I watched 3 to 4 other videos to understand DNA fingerprinting but none of them cleared the topic as u did thanksssss
@LearningCurveScience3 жыл бұрын
Thank you very much for saying that. I'm glad you found my explanation useful. Even though the radioactive DNA method isn't really used anymore, it is still used in teaching.
@rehmanrupiya7587 Жыл бұрын
I have tried multiple times to understand from our NCERT textbook but everytime i failed. Thank you so much for explaining in a very simple way.
@Eterrath2 жыл бұрын
This is an amazing video. I've seen multiple videos on DNA fingerprinting and this is the only one that manages to answer all my curious high school level questions without being too technical to fry my brain. Glad you're still uploading videos. Hugely underrated. Subscribed.
@LearningCurveScience2 жыл бұрын
Thank you very much. I am actually an educator in the UK, and so I try to make my videos understandable by as many people as possible. I'm glad you enjoyed it, and thank you very much for subscribing
@learner32682 жыл бұрын
Same here
@robertm712011 ай бұрын
Finally !! An explanation of how a DNA sample can be transformed into a DNA profile ! Thank you so much.
@shmkrar115311 ай бұрын
This video is awesome! I had great trouble understanding DNA fingerprinting. Now, I've got it and find it really fascinating
@normannokes9513 Жыл бұрын
The world has received a wonderful gift. Undeniable evidence will upset many corruptible personalities. Thank you Sir Alec.
@tinopetersson25772 жыл бұрын
Why does this channel not have more subscribers? Thank you for a great piece of content!
@LearningCurveScience2 жыл бұрын
Thank you very much for the lovely comments.
@mamtalall6750 Жыл бұрын
Sir, your explanation is simple and so easy to understand. Especially for students in a resource poor set up. Thank you so much.
@andydrews44392 жыл бұрын
I did a gel electrophoresis lab in my cell biology lab. Took us three weeks to complete. Very cool.
@kinjalchandpara86033 жыл бұрын
Excellent !!!!!!!🙌🏻 None can forget this topic after watching this video. Very well explained 👌🏻
@LearningCurveScience3 жыл бұрын
Thank you very much for such a lovely comment. I'm glad you enjoyed it.
@learner32682 жыл бұрын
First time ever being able to understand DNA profiling in a much better way after watching a number of videos finally
@WitchyLady214 ай бұрын
Loved the Doctor Who reference! Great video! Thank you for doing this. It helped me pass my class. :)
@Itachi-15039 ай бұрын
3D visualisation is the best way of teaching so that all can get it very easily... Your explanation is amazing... Keep it up🎉🎉
@Mikeymouse1 Жыл бұрын
Thank you so much. I normally need very detailed explanation with visual and this is perfect. 😊
@islamicbro2 жыл бұрын
I saw tooo many videos of dna fingerprinting. But this one is what I was looking for❤️
@LearningCurveScience2 жыл бұрын
Thank you very much for your lovely comment
@wonderman85372 жыл бұрын
Oh my goodness me. I can't believe this is a 2k sub channel and such professional video
@chiumanhin6183 жыл бұрын
I have been looking for video like this so long!!thankyouuuuuu!
@LearningCurveScience3 жыл бұрын
Good, I'm glad you found what you were looking for. Thank you for watching.
@eduardoborges12023 жыл бұрын
Man, you did a great job here. Thanks.
@LearningCurveScience3 жыл бұрын
Thank you very much. I'm glad that you enjoyed the video.
@noorashaju78922 жыл бұрын
And finally here it is.. This still helps a lot for me. Thank you so much sir for your wonderful explanation.
@ReflectiveLayerFilm3 жыл бұрын
Great video/explanation. Now I know why it's expensive to do DNA fingerprinting.
@LearningCurveScience3 жыл бұрын
Thank you, I thought I'd go back to my biological roots for a video. Biology is my comfort zone I suppose. For quite a few years, there was only 1 lab in the world doing DNA fingerprints.
@WanderingKnights3 жыл бұрын
You are great at explaining
@LearningCurveScience3 жыл бұрын
Thank you, I'm glad you think so. DNA is such a fascinating molecule.
@HEARDIFFERENT3 жыл бұрын
Excellent video once again. ❤️❤️❤️👏👏👏🔥🔥🔥
@LearningCurveScience3 жыл бұрын
Thanks very much. I'm so glad you enjoy my videos. Thank you.
@mimansamishra58333 жыл бұрын
Your videos are really helpful!
@LearningCurveScience3 жыл бұрын
Thank you very much. I'm glad you enjoy them.
@savanrathod60212 жыл бұрын
Very simply explained,thank you sir
@gulshanmaurya55122 жыл бұрын
Great explain ❤️ love from India 🇮🇳
@lilyc3028 ай бұрын
great explanation, other youtube videos were too vague
@ShortsOG1232 жыл бұрын
Thanku so much it is the bestt explanation on DNA fingerprinting💕
@diegocorales92842 жыл бұрын
2:02 is epic!
@LearningCurveScience2 жыл бұрын
Thank you I'm glad you enjoyed the video
@janebarnes4386 Жыл бұрын
Back to class. I’ll get a c- w all science classes. -an MA + writer
@virenderbhardwaj3137 Жыл бұрын
4:20 how do we make these probes? ...i.e how do we know they're gonna be complementary to the sample dna pieces??
@ghoulwizard19013 жыл бұрын
I don’t really get the part where the pieces of complementary DNA are made radioactive. Can you elaborate on that? So the pieces of DNA added are complementary to the DNA strand we used as sample?
@LearningCurveScience3 жыл бұрын
Yes I use pieces of DNA that I know to be complementary to the sequences in the sample. These pieces of DNA are made artificially and are made to be radioactive. We do the same thing today with pieces of DNA that have dye molecules attached to them. It just helps us to see where our DNA samples ended up. I hope that helps.
@ghoulwizard19013 жыл бұрын
@@LearningCurveScience Oh, thank you so much! I understand now!
@nazlkarac5367 Жыл бұрын
thank you for this amazing video from Türkiye
@wicked.peaches.1797 Жыл бұрын
Loved the explanation and Doctor Who reference. 😂
@akshitaaaaatiwari25683 жыл бұрын
Awsomeeeeeeee
@LearningCurveScience3 жыл бұрын
Thank you very much, that's very kind
@daytodayupdate59223 жыл бұрын
Very well explained. Do we use EtBr in gel electrophoresis step of fingerprinting? If not then what is the reason of it?
@LearningCurveScience3 жыл бұрын
Ethidium Bromide is a dye that fluoresces in the presence of DNA. It is usually used to make the band more easy to see. It means you don't have to bother with the radioactive DNA probes.
@manar-nasser2 жыл бұрын
Your voice make me feel like I'm watching a movie
@MezGaming-zp5ei4 ай бұрын
Now i understood Thanks!
@ashishrokade3488 Жыл бұрын
Thank you so much
@kiranyadav73873 жыл бұрын
is there any relation between the restriction enzymes used in RFLP and location of STRs?
@LearningCurveScience3 жыл бұрын
Interesting question. I'm not entirely sure. You need to make sure that a cut is made before the STR and then again after the STR. As long as the cuts are made in the same place in everyone's DNA, then it is just the length of the STR that differs.
@steamerSama2 жыл бұрын
gr8 video mate
@LearningCurveScience2 жыл бұрын
Thank you very much, I'm glad you enjoyed it.
@vachan-maker Жыл бұрын
excellent
@unknown59042 жыл бұрын
Why don't we stop after electrophoresis, isn't there a dye that is added to the fragments during electrophoresis. I mean when is it necessary to continue to jeffreys technique?
@LearningCurveScience2 жыл бұрын
That's a good question, and the answer I don't really know, but I have some ideas. Firstly this is the technique that is often used in education. Also having seen a number of these gels, they lose water and shrivel with time. This would alter the gel and potentially make them unusable. Also I'm not sure how stable. There are solutions that do use dye (I've used some myself). Sadly when they dry out they become unusable. Hope that helps.
@unknown59042 жыл бұрын
@@LearningCurveScience oh thanks so much
@globaltutorialscenterkawar41768 ай бұрын
Thanks sir
@tamarafakih10802 жыл бұрын
thank you so much this was very beneficial but i wanted to ask on which basis is the radioactive probe chosen, or to be clearer, what is the specific DNA sequence that i want it to be hybridized by this probe and why?
@Okamy19932 жыл бұрын
You dont need to tag the bases, for example it can pair with the Phosphate or sugar Rests every DNA has.
@laladnikuku3ka3 жыл бұрын
thank you for the video
@LearningCurveScience3 жыл бұрын
You're welcome. I'm glad you enjoyed it.
@noureenadil1612 Жыл бұрын
Wonderful 👍
@girishshankarrai64883 жыл бұрын
Sir the repeative sequence which are found in the fragments why they are only present in narrow band which are rich in A T content 🤷🏻♀️
@LearningCurveScience3 жыл бұрын
That's a really interesting question, thank you. I'm not sure why the sequences are found in narrow bands, but since they are non-coding they would not be affected by mutations that add extra copies of the sequences (these can happen at any time). Also quite a few of them are rich in A and T, but not all of them. The STR called FGA has the sequence CTTT, but it does appear that a lot of them have A and T. I'm not sure why, but excellent question.
@vivekgautam69433 жыл бұрын
U r wonderful buddy.
@LearningCurveScience3 жыл бұрын
Thank you, I'm glad you enjoyed the video
@pankajakshigk78422 жыл бұрын
Thank you very much It was very helpfull
@ayushpandeymbbs17762 жыл бұрын
Sir after gelectrophoresis if both semple has diffrent arrangement of DNA fragments then here why we can not decide both DNA semple are of different persons????.... Why we go further and perform autoradiography and all ???????
@ayushpandeymbbs17762 жыл бұрын
We can see DNA arrangement in gel electrophoresis strp by stanning with ethidium bromide and UV rays ...????
@LearningCurveScience2 жыл бұрын
The method I discussed is just one way of making the fragments visible. We need to make them visible to see if there are any differences. This is just one way, and it's the way that's usually taught in schools (in the UK at least). I hope that makes sense
@ayushpandeymbbs17762 жыл бұрын
@@LearningCurveScience ok sir love from India ❤️
@moutaihaitam29597 ай бұрын
is the same analysis we do to identify the parents ?
@LearningCurveScience7 ай бұрын
Yes it is, it works on the same principle.
@ThePhotogalleria3 жыл бұрын
The radioactive method has not been used since 1995 or so. So this video outdated some 25 years ago.
@LearningCurveScience3 жыл бұрын
Ooh interesting, I didn't know that, thank you. I'm a teacher rather than a research biologist and the radioactive probe technique is still taught. I know we don't use the RFLP analysis anymore but I thought it was interesting so I included it in the video. Whenever I've done a gel electrophoresis I've always used dyed probes, but I always assumed they were just used for education. Interesting to learn something new, thank you.
@PrakashChandraJoshii2 жыл бұрын
Fucking deep hard next level explaining man 🏆🔥🙏
@LearningCurveScience2 жыл бұрын
Thank you very much, I'm glad you enjoyed it
@nishantraj4403 жыл бұрын
wow ❤
@LearningCurveScience2 жыл бұрын
DNA is awesome, I find it fascinating. Thank you for watching the video.
@safazuhair2420 Жыл бұрын
thank you so mush 😭 thank you thank you soooo much , allah bless you ❤
@AnnaRossa60882 жыл бұрын
Doctor who reference!
@LearningCurveScience2 жыл бұрын
I am a massive Doctor Who fan and geek. My time travel is full of Doctor Who references (and I do mean full)