Antiphospholipid Antibody Syndrome

[@gto11520]

Patient with lupus has a higher chance of developing APS, you should suggest a mixing study ie dRVVT assay prolong drvvt + normal plasma if corrrected -factor deficiency and if not corrected then suggest a presence of lupus. Confirmatory test followup adding excess phopholipd clotting should normalize.

[@eruiluvatar4526]

I'm sorry I still don't get it. So the antibodies target and attack the phospholipids, which are fat acids that bind on the the coagulant factors (on the cell membranes). Due to these attacks the patient's physiological ability to perform a normal haemostasis is interrupted, disturbed. So how does a thrombosis occur? Is it because the cell membrane is attacked, which leads to cell lysis whereafter an accumulation of the cell materials? Update: after a little digging; so the thrombosis occurs because the antibodies do attack but also promote the epithelial cells, thrombocytes and WBC to form a clot. Correct? So they damage but promote?

[@barathvenkateshr4494]

Now u got it?

[@beniamino7733]

thank you very much. it was very helpful to me.

[@Learningin10]

It's our pleasure, we're glad you liked it! Subscribe to us to keep in touch and visit www.learningin10.com to know more about us! Best regards, Learning in 10

[@promamushreki4263]

spellbound! very nice. I think you can add about other treatment modalities such as eculizumab in refractory case/ aPL nephropathy, immunomodulator in autoimmune hemolytic anaemia/ thrombocytopenia.

[@tysonchickennugget]

how likley would it be when tested the 2nd time ,when the first test was high

[@kasahunbentimerga3006]

Nice presentation

[@nakayestella-tb7lq]

Thank you

[@dr.bramantyonugraha3034]

Thank You. So helpful.

[@Nebatnani-dh3ku]

Crystal clear 👌

[@tubeysr]

Why does thrombosis occur if there is a defect in anti coagulation (anti phospholipid)?

[@helloagain1400]

Anti coagulation factors are the prinple of measuring how much the blood coagulate Just like gas in the car without it wont move

[@patient3841]

Thx

[@r.i.a6485]

Thanks a lot

[@Learningin10]

It's our pleasure, we're glad you liked it! Subscribe to us to keep in touch and visit www.learningin10.com to know more about us! Best regards, Learning in 10

[@angadsingh5776]

Nice video

[@salammohammed6543]

Thank U

[@Rina.136]

To the point!

[@EAGLE-yf5bf]

Thanks alot mam!

[@SoShyMeka]

Beta-2 Glycoprotein I Ab, IgG

[@zachariahsmith9130]

Not much honestly. You need other labs to correlate

[@Natureboy_23]

I was diagnosed with lupus anticoagulant im a 28 year old male i dont have lupus this came out of nowhere i had dvt and pe and idk wat to do i feel lost and defeated at times

[@ljhendrickson2960]

Have you seen a hematologist or a rheumatologist? Best place to start. God bless.

[@thomasserge7359]

What causes coagulation disorders in the presence of the antiphospholipid antibody syndrome?

[@jenniferfrances8793]

Johnson and Johnson vaccine

[@stefanshen1622]

@@jenniferfrances8793 F. Lol

[@anomalyp8584]

coagulation can happen spontaneously, but triggers like infection or inflammation, trauma, immobilisation,... are the most common findings in trombosis events.

[@azieziera6596]

Is there any way to cure APS?

[@sabe1840]

❤❤

[@Wildewhitley]

I have APS, suffered these "treatments" for 34 years, and finally learned it was all coming from food! 5 months ago I went to a 100% organic diet, and am seeing more progress in that time, than I have in my entire life! I'm talking all around health people! It's all improving.....It's diet! Diet!!!! I tell you!!!!!!

[@tubeysr]

Let us know after a year how you feel.

[@chestnutmair1]

I have started Mediterranean diet. I am hoping this will help

[@jonathanstempleton7864]

"It's made from people!" How you getting on?

[@jonathanstempleton7864]

​@@chestnutmair1 Is that pizza?

[@Wildewhitley]

@@jonathanstempleton7864 not sure your asking me but I'm getting along great! Diet has completely changed my life in every way!

[@hasanulislam7029]

Boring 🪴