Lidocaine Pharmacology

[@cathysungbinyi9163]

Thank you Dale, it is easy to understand, best teaching

[@ayushdogra8103]

Isn’t it that lidocaine blocks the sodium channels in Inactivated state , which means depolarisation has already occurred , so there might be just a small deflection rather than such an appreciable change in slope ??

[@sjayveenth]

Simplest explanation

[@khadeenherbert478]

this was a great explanation thankyouuuuuuu

[@Laila-lr6pv]

So good!! thank you

[@johnathanabrams8434]

Is there anything dietary that can alter sodium channels, intracellular calcium, potassium channels or acetylcholinesterase ?

[@jesseconnors143]

I thought lidocaine shortened the refractory period? Class Ia lengthen (quinidine), 1b shorten (lidocaine), 1c neutral (flecanide)

[@BrianRKocak]

I think you are right. What he is describing is more akin to amio (though acting on potassium and not sodium channels)