Life in the Lab: A malaria genome modification pipeline

Frank Schwach is a senior computational biologist, working in the malaria group at the Wellcome Trust Sanger Institute. In this film he gives an overview of the main processes involved in developing and creating malaria vectors as part of the PlasmoGEM project. Frank discusses how he develops software to create DNA sequences used to modify the DNA of malaria parasites. He also outlines some of the processes involved in creating the vectors in the lab, ready for use by scientists around the world.
The Malaria programme uses a variety of different research methods to understand the biology of the Plasmodium parasite, its mosquito vector and the human host. This scientific approach aims to find solutions to malaria control such as discovering new drugs and vaccines.
This is one of a series of Life in the lab films providing a more in-depth insight to some of the laboratory processes used by different teams at the Wellcome Trust Sanger Institute. The film has been developed to help support the OCR Cambridge Technical Level 3 in laboratory skills.

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