Arachidonic Acid Pathway- The most Comprehensive Explanation - COX-1, COX-2, LOX,Prostaglandin, LTNs

[@MedicosisPerfectionalis]

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[@joshdudeguy2830]

Me *comes to video knowing absolutely NOTHING about the arichidonic acid pathway* MP *makes 18 minute video full of freaking magic* Me *leaves at end of video feeling like a subject matter expert* I know this is a 4 year old video but still. You do incredibly important work here, man! Thank you!

[@MedicosisPerfectionalis]

Thank you!

[@Mandh223]

Whoever you are, you’re just absolutely an amazing teacher! God bless you

[@MedicosisPerfectionalis]

😊😊😊

[@MedicosisPerfectionalis]

Please consider sharing my videos with others...Thanks in advance!

[@samuelwaithira]

A comedy pharmacology class, you have made my day, in autocoids am now good.

[@something93565]

@@MedicosisPerfectionalis always do!!! your dry sense of humor makes it all even better! made in egypt vibes ;) love it.

[@moonprincess1992]

My professor didn't even attempt to teach this, just gave us a chart to memorize. So thank you for explaining everything so well!!

[@MedicosisPerfectionalis]

You’re very welcome 😊 Good luck 🍀 Let me know if you have any questions!

[@yes7855]

Same here hahah. And these vids are great! :)

[@yui870]

yeah my doctors too .. never told me diz (in my campus there's no proffesor, just doctors until doctorate degree)

[@mariamlatif5095]

Share kardein chart

[@tauqeerahmadsafi8522]

You are lucky to have a professor 😅

[@Deepayan00]

I am rewriting an article on "arachidonic acid, inflammation and mental health" and needed to know the whole mechanism. This video gave me a head start to decode the overly densed wiki article on arachidonic acid and saved my mental health. :D

[@mariansmith9685]

Where can I read your findings? I'm really excited to see your work!

[@mossaybo]

15:21 to 16:10 was the best explanation of the pharmacology behind Aspirin , since it's invention !

[@MedicosisPerfectionalis]

Thanks, dear!

[@mossaybo]

@@MedicosisPerfectionalis I'm the one who should thank you , I'd love to know , when you're learning about a new subject , how do you approach it ? .. reading different textbooks , sticking with one book , reading research papers about it ? because you have an amazing big picture and you make smart connections between things , I'd appreciate it if you'd teach us how to fish

[@wcomsa]

This is the best explanation, I watched before for my presentation preparation and now I'm watching it again for my final exam. I'm so grateful thank you

[@MedicosisPerfectionalis]

Excellent!

[@miradl]

This truly made my night! Who knows learning the AA pathway (that I've been dying to defy since medschool) can be fun?! 7 years later and this made sense

[@MedicosisPerfectionalis]

I appreciate you!

[@MrNakedWizard]

Thank you, banging my head against a wall to learn this and your style of repetition and humour was wonderful and refreshing, thank you again

[@MedicosisPerfectionalis]

My pleasure 😇 I am so glad you liked my video. Can you please help me by sharing?

[@josetrujillo738]

Lol

[@alibuknan193]

Thank you so much, you got me laughing while watching this and learn :)

[@MedicosisPerfectionalis]

Always laugh 😆 😂

[@ameerahal-sadi9596]

Love love love your teaching style!! You're making immuno more doable!

[@MedicosisPerfectionalis]

Thanks 🙏

[@abcgames4454]

The most doubt clearing video I have ever seen. A must for every medical student. Love from India! 🇮🇳👩‍⚕️

[@MedicosisPerfectionalis]

Thank you so much 😊

[@dh1147]

Holy moly, I “learned” this in nutritional biochemistry and in pathophysiology and after watching your video, I finally get it!!!! Thank you, subbed and saved! Thank you you are amazing!

[@MedicosisPerfectionalis]

I really appreciate you!

[@sharonkende4774]

Thank you so much. I am a nutrition student but hearing how meds work made the information so much more retainable. the difference between teaching vs teaching and the student learning is timing and ways to engage (showing connections between things and even adding humor). It makes all the difference.

[@MedicosisPerfectionalis]

Thank you so much 😊

[@MedicosisPerfectionalis]

💊 Pharmacology Playlist: kzbin.info/aero/PLYcLrRDaR8_d5RzuEJprW-NWXTK22ByVC&si=MGlX4_a2LlLOo6Ed

[@nfa861]

thank you sir you are essential to humanity and deserve a nobel prize 🏆

[@snehasha6891]

This is HANDS DOWN THE BEST video on arachidonic acid pathway

[@eduardocarvalho7810]

I don't generelly make comments, but this lecture was AMAZING. Very clear and engaging explanation, congrats and THANK YOU!

[@MedicosisPerfectionalis]

Thank you 😊

[@BitseatGetaneh]

aren't you the best??? wow!!!! YOU MADE ME UNDERTSTAND THIS IN AN EASY AND DIGESTABLE WAYYY! Love how you repeat it as well to make us remember

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where has this channel been my whole life

[@MedicosisPerfectionalis]

Hiding in a haystack 😊😊

[@FlowRXOXOXO]

Love the sense of humor with the teachings!

[@MedicosisPerfectionalis]

Thank you!

[@fionacole7811]

Thank you so much❤❤ i have a biochem exam tomorrow on this and you just about saved my life (gpa)

[@dge.]

Came across your video while studying for Pharmacology. I am so glad I did! Not only did you make it so simple, but I was laughing throughout the video, too! Ps I'm surprised at how low the view count for this is. Honestly this is better than Khan Academy. It uses a white background and u managed to inject bouts of humor (which I think is so hard to do for topics like these) I hope you continue on making videos, my good sir! You have made a medical student's week 😊 I wish all of my lecturers were like you.... SUBBED!

[@MedicosisPerfectionalis]

Thanks a ton! I am honored...You’re such a kind person. Can you please help me by sharing my videos with your friends?

[@dge.]

Do you have any videos on anticonvulsants? 😄 also, I've sent this video to a ton of my classmates! They loved it!!!

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I wish there was a way to like and subscribe 1000x times srsly u have the BEST Hematology lectures eveeeeer thank you so much and GOD bless you

[@MedicosisPerfectionalis]

Thank you so much 😊 God bless you too!

[@laibasheikh137]

This was explained 10x better than it was at my university. Thank you so much!

[@partomeraji3084]

every single time I cry with happiness... Medicosis you are a gift from God

[@MedicosisPerfectionalis]

Thank you so much ☺️

[@mehdiazaz7669]

the best professor I've ever seen, good job !

[@MedicosisPerfectionalis]

Thank you 🙏

[@lorena6020]

Who are you? You are too good! I have to study for my periodontology exam but this is way better! Thank you!

[@MedicosisPerfectionalis]

My pleasure!

[@KazokuMugiwara]

Thanks for the video. It went more in depth than my dental pharmacology textbook and helps me picture this action.

[@MedicosisPerfectionalis]

Awesome 👏 Thank you so much 😊 Can you please help me by sharing?

[@shubhampatil4496]

I never understood this in my second prof ..And the fear of this topic stayed with me for too long.Thankyou for such simple easy explanations

[@akaakram1347]

I am starting to lern with love&fun our medical lectures than i just find this masterpiece..thank god and may the god bless you 🫀

[@MedicosisPerfectionalis]

God bless you too!

[@ieorj4080]

This is the BEST video I have seen on this topic. Thank you kind sir.

[@MedicosisPerfectionalis]

Thank you so much 😊

[@rimshaabdullah8373]

You proved that.. yes I am medicosis perfectionalis love your method of teaching you are best 💗

[@MedicosisPerfectionalis]

Thank you so much 😊

[@charlemagnebaguio3734]

Been sharing this golden content to my friends! Thank you for this and thank you for being a great teacher.

[@MedicosisPerfectionalis]

My pleasure 😇 Thank you so much 😊

[@LisaClarkmedicalillustrator]

I couldn't love your teaching style more! Fantastic.

[@MedicosisPerfectionalis]

Thank you 😊

[@MedicosisPerfectionalis]

From the arachidonic acid pathway, can you mention some side effects of Acetyl-Salicylic Acid (ASA)?

[@ricardobaroni1714]

Bleeding, peptic ulcer (decreases production of mucus)

[@MedicosisPerfectionalis]

Good...and why does it decrease production of mucus?

[@ricardobaroni1714]

@@MedicosisPerfectionalis Because ASA inhibits the COX pathway, consequentely inhibits the production of prostaglandins, wich are responsable for the production of mucus. Sorry for my english, I am still learning haha

[@MedicosisPerfectionalis]

You’re excellent 👍

[@chiahead52]

You speak my language MP! Acronyms and association helps better memory retention. Thank you

[@MedicosisPerfectionalis]

My pleasure!

[@shadysid5570]

Best education channel on KZbin

[@MedicosisPerfectionalis]

Thank you 🙏

[@CeliaHH1]

Thank you so much! Many greetings from Germany!

[@MedicosisPerfectionalis]

My pleasure 😇

[@NightWiitchh]

Absolutely loved the video!!! It was wonderful and not confusing at all. I am currently in Pharmacology and everything makes since now!!

[@MedicosisPerfectionalis]

Thank you so much 😊

[@j.sbhandari8813]

what an explanation, PERFECT MAN! thank you so much and God bless!

[@MedicosisPerfectionalis]

My pleasure 😇 God bless you too!

[@drtahirakhtar2485]

Thank you so much for this masterpiece, this is really helpful for medical students and I am sure no body will deny this fact, 💯

[@MedicosisPerfectionalis]

Thank you 🙏

[@edthoreum7625]

4:35 5:40 7:20 platelets as H2O pump 13:48 aspirin

[@shyamagrawal36]

First time ever I could understand the exact mechanism by this video.. Thanks

[@MedicosisPerfectionalis]

My pleasure!

[@aboodmoghraby4647]

When a young guy beats our professors Great respect for you bro🌺

[@MedicosisPerfectionalis]

Thank you ☺️

[@afsa2973]

Thank you for the wonderful lecture . Love from India 🇮🇳.

[@MedicosisPerfectionalis]

Thanks 🙏 Love you back!

[@SaraMicallef]

This textbook chapter traumatised me. Thanks for undoing the damage :)

[@MedicosisPerfectionalis]

Wow 🤩 Thank you 😊

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You are so freaking genius!!! Can’t say how much u make medicine interesting and logic 🥺🧡🧡

[@MedicosisPerfectionalis]

Thank you 🙏

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This looks like heaven thanx from Egypt

[@MedicosisPerfectionalis]

Thank you 😊

[@sxvioux]

Wow I never knew Studying these mechanism will be a lot of fun, its so colourful and I love how u throw jokes sometimes. Keep up the amazing work. 💙💙🥺

[@MedicosisPerfectionalis]

Thank you so much 😊

[@swally1206]

I love the way you make life easier, that was incredible and so helpful, thank you so much.🤩😁🙏🏻 I wish you were my Doctor at Uni😅

[@MedicosisPerfectionalis]

Thank you so much 😊

[@alibaldiwala1604]

THIS IS A CRIMINALLY COOL EXPLANATION! Thank you so much!🤯❤

[@parishaykhan8139]

We need more lectures on pharmacology plz upload ...waiting ...God bless you

[@MedicosisPerfectionalis]

Sure!

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My life would have been smooth af in freshman year if these existed, DANG. So glad I stumbled upon this

[@MedicosisPerfectionalis]

My pleasure 😇 Can you please help me by sharing?

[@YusraAli313]

I actually Love you, you are so entertaining it's not funny! haha Education on another level. Thank you doctor xxxxx

[@MedicosisPerfectionalis]

My pleasure 😇 Thank you so much for watching!

[@farhinsiddeka]

This really is the most beautiful thorough explanation! Thank You!

[@MedicosisPerfectionalis]

Thank you so much 😊

[@a_a_n_i]

Gosh your explanation was amazing!!! The way you made every single step funny was just cute and helped me memorize them easily, i'm preparing a presentation about arachidonic acid derivatives and was very worried where to find information cuz there isn't much to find, your video is the best, couldn't be better, thank you! 😭

[@MedicosisPerfectionalis]

My pleasure!

[@daingfirdaus7951]

The explanation is crazy yet understandable

[@SW-fk3rb]

You are funny!! Really enjoyed this, so delighted I found your channel.

[@MedicosisPerfectionalis]

Thank you 😊

[@becky5950]

This made everything so crystal clear, thank you!

[@MedicosisPerfectionalis]

My pleasure!

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Man. This is masterpiece

[@MedicosisPerfectionalis]

I really appreciate you!

[@josephbanoub8392]

Excellent presentation and I am really impressed how you could simplify the science Thanks

[@MedicosisPerfectionalis]

My pleasure 😇

[@lisameller1]

Thanks for making this easier to understand!

[@wafaeltaief723]

Looooove this one it makes sence in an amazing way , may god bless you medicosis 🥰

[@MedicosisPerfectionalis]

Thank you so much 😊 God bless you too!

[@osayamenogiugo3864]

Thank you! Thoroughly enjoyed learning.🙌🏾

[@MedicosisPerfectionalis]

My pleasure 😇

[@qusai1437]

I CANT THANK YOU ENOUGH !!!!!!

[@MedicosisPerfectionalis]

Thank you ☺️

[@rizz1088]

The way you teach is similar with my biochemistry teacher in medschool. ❤

[@MedicosisPerfectionalis]

Great 👍

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This is genius as always .. thanks doc. Bless you

[@MedicosisPerfectionalis]

Thanks bro, bless you too!

[@ishaqureshi402]

I was emotional cuz I watched sth emotional just before starting this lecture. My tears still hadn't dried up when he talked about Aristotle's deduction followed by 'Buhahah' which cracked me up. Thank you. I am back.

[@MedicosisPerfectionalis]

You’re very welcome!

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Wow. Great job. I like how you think. This works for me!

[@MedicosisPerfectionalis]

Awesome 👏 Thanks 🙏 Can you please help me by sharing?

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The best explanation! Bravo 👏🏻

[@MedicosisPerfectionalis]

Thank you!

[@garrett_jp]

Loved this, very helpful. Thank you!

[@MedicosisPerfectionalis]

So glad!

[@lostSempaiWissame]

Your laugh always cracks me up .. thanks a bunch

[@MedicosisPerfectionalis]

You’re always welcome 🙏

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Me when I watch other educational vids: *nods* yeah okay. Thank you Me while i watch medicosis perfectionalis: *smiles* *chuckles* haha yeah. I understand better now✨ thank you 🥺💕

[@MedicosisPerfectionalis]

Haha 😂 You’re awesome 👏 Thank you so much for watching!

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i m about to sit for my Professional Exam in 5 days and this playlist makes my 5yrs in medsch into sense 🤧🤯

[@MedicosisPerfectionalis]

Good luck 🍀

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I love how easy it seems when u explain it. Tnx so much 🌹🙏

[@MedicosisPerfectionalis]

My pleasure 😇

[@danielnaranjodelpino7895]

Hermano se te fue la manoooo! Muy buen video. Excelente. al fin entendi esto!!

[@radojemarkovic5290]

Man, I I'll post another same comment. This i s masterpiece. Now I understand corticosteroidss and aspirin use( never knew why would drug which inhibit inflammation inhibit trombs) .

[@MedicosisPerfectionalis]

Thank you 🙏

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You are simply EXCELLENT!!!

[@MedicosisPerfectionalis]

Thank you so much 😊 I appreciate it

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God bless you ,indeed I benefit alot from you Sir

[@MedicosisPerfectionalis]

Thank you!

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Thank you for making medicine fun!🤗🤌

[@MedicosisPerfectionalis]

My pleasure 😇

[@keurinrin16]

It would be nice if we could have a pdf form of your notes hehehe because it is much understandable than reading books lol

[@MedicosisPerfectionalis]

I do actually...Here: www.medicosisperfectionalis.com/products/illustrated-notes-pdfs/

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You are my Savior ! Thank you ❤️

[@MedicosisPerfectionalis]

Happy to help!

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Thank you ,your explanations are just awesome 👌

[@MedicosisPerfectionalis]

I am so glad!

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This was amazing, thank you so much!!

[@MedicosisPerfectionalis]

My pleasure 😇

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Great video!! Love your ironic sense of humor!!!🤓😂

[@MedicosisPerfectionalis]

Haha 😂😂 Thank you 😃

[@ricardobaroni1714]

Hello from Brazil... this channel is amazing, please keep the good work!

[@MedicosisPerfectionalis]

Thanks, brother, for your encouragement 👍

[@ricardobaroni1714]

@@MedicosisPerfectionalis I am very grateful for this channel You really left the content fun and didactic.

[@dianareyna8889]

You are right, best explanation!

[@MedicosisPerfectionalis]

Thank you so much 😊

[@elenamirova7990]

Thank you for the great explanation and the great content you put out regularly! Your videos are of great help when preparing for exams :D About the anti-platelet activity of aspirin, despite its inhibition on prostacyclin synthesis, I found this piece of information in Voet's Principles of Biochemistry: "Vascular endothelial cells are not so drastically affected, since, for the most part, they are far from the site where aspirin is absorbed, are exposed to lesser concentrations of aspirin and, in any case, can synthesize additional PGH2 synthase".

[@MedicosisPerfectionalis]

Excellent! Thank you so much 😊

[@nikolamarkovic4845]

i dont understand. how are endothelial cell far from aspirin ? endotleh covers all of blood vessels, so ist it all around the body?

[@erykahbrown9239]

Additionally, as I've now learned in my hematology course, since epithelial cells have nuclei they have the ability to regenerate cyclooxygenase whereas platelets, being only cell fragments have no nucleus and lack this ability

[@tashreeqa_ek]

Absolute lifesaver

[@MedicosisPerfectionalis]

Thank you so much 😊 Would you please help me by sharing?

[@thathaw7769]

Indeed the best explanation! Thank you!

[@MedicosisPerfectionalis]

My pleasure 😇

[@fazalwahid9950]

Excellent easy and clear vision 👌 Thanks dear you are doing a good job. Please keep it up

[@MedicosisPerfectionalis]

Thank you 🙏

[@drneelagiriparameshwar4219]

That was smooth 👍💓

[@MedicosisPerfectionalis]

Thank you 🙏

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you are.so ingenious too~~~thankyouuuu

[@MedicosisPerfectionalis]

Thank you so much ☺️

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You have got my respect dude. ❤

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You are just a legend. hat off for you

[@MedicosisPerfectionalis]

Thank you 😊

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This ssssssssso great explanation 😮❤❤❤❤❤❤

[@MedicosisPerfectionalis]

Thank you 🙏

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Ive always been a fan and you've saved my ass since year 1 till the 3rd I'm in rn, 3 more to go :D

[@MedicosisPerfectionalis]

I appreciate you!

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You are the best! Thank you.

[@MedicosisPerfectionalis]

Thank you so much 😊

[@MrSaloha]

Please make neurology Medicine series like hemiplegia and para... Again you’re the best...

[@MedicosisPerfectionalis]

I appreciate it

[@sammay4063]

A very helpful and clear video

[@MedicosisPerfectionalis]

Thanks, a lot! Can you please help me by sharing?