Meiosis! (Mr. W's Music Video)

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SUMMARY: This song explains the process of meiosis, which produces sex cells, or gametes, like sperm and eggs cells. It starts with diploid germ cells in the testes and ovaries, which have pairs of chromosomes from both parents. Through meiosis, the chromosome number is halved, creating haploid cells with genetic variation. Key steps include DNA replication in interphase, chromosome pairing and crossing over in prophase I, and the random assortment of chromosomes in metaphase I, leading to genetic diversity. The song also highlights the importance of meiosis in creating unique offspring, preventing clones, and contributing to evolution. Meiosis II mirrors mitosis, where chromatids are separated, completing the process.
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Lyrics
Meiosis, it's how we make sex cells, or gametes
The sperm cells or egg cells performing the feat
Of moving genes forward in eukaryotes like orchids and bees.
Meiosis doesn't happen in all cells of the body
There's just a few cells that have this hobby
I'm talking 'bout germ cells in testes and ovaries,
Germ cells are diploid and what that means,
Is that the chomosomes are matched up in teams,
In each pair one's from your dad, one's from your mother.
And when you line up the chromosomes it's suddenly clear
How each is a member of a matched up pair,
Homologous pairs, each a homologue of the other.
In humans,the diploid number's forty six,
And a key trick that happens in meiosis
is dividing that number in half to 23
And that single set of chromosomes has its own name
It's called "haploid" in this meiotic game.
So diploid to haploid's a key meiotic strategy.
CHORUS
Meiosis, makes eggs and sperm
It's the same in the robin as it is in the worm.
Makes haploid gametes with recombination,
Meiosis creates variation!
In interphase I meiosis starts,
It's the DNA replication part
An evolutionary relic of its origin,
'Cause meiosis evolved from mitosis you see,
So each process starts identically
Replicating chromosomes into two sister chromatids.
In Prophase I chromosomes coil up, and homologous pairs pair up,
Forming tetrads, each with chromatids four.
A chiasma's the spot where the chromatids link
And synapsis is the name for the whole darn thing,
And crossing over is what this whole process is for.
See the homologues aren't identical twins-- no way!
They're not the same DNA
The genes are the same but the alleles might take different forms,
So during synapsis alleles can cross over,
Between homologues, and when it's all over,
There are gene combinations that have never been seen before.
CHORUS
Another meiotic variety creator,
Is metaphase one with homologues at the equator,
Cause how each pair lines up is random and independent,
So in one pair facing north might be the maternal,
In the next one it might be the paternal,
It's a one in two shot, it's called independent assortment.
So two pairs divide up in four distinct ways,
It's two to the number of pairs, you could say
So think 'bout us humans with 23 homologous pairs
Two to the 23rd power is a number so great,
Is 8 million,three eighty eight thousand, six-oh-eight
That's why metaphase one is a variety creating affair
And now connect this assortment with recombination,
Note that what we've got during gamete creation,
Is sperm and egg cells that are absolutely unique
So if you ever wondered how sisters and brothers,
Can be so different from one another,
Remeber these meotic recombining techniques.
BRIDGE
And if meiosis had never evolved
The book of life would be a very different tome.
Cause if it wasn't for meiosis
All offspring would be clones!
For complete lyrics, download the sciencemusicvideos songbook at apbiosuccess.c...