The longevity treatment no one’s talking about: Peter Attia, M.D. | mbg Podcast

[@xnixor]

As a medical surgical RN, Dr Attia has confirmed a lot of things Ive suspected but never articulated when it comes to risks and healthspan. I can and do listen to him for hours. Awesome content always.

[@susangreen5777]

We are NOT overnurished, we are undernourished BUT OVERFED.

[@goddessofamarna]

Exactly

[@lilydauber3147]

Nutrient-density/fiber deficiencies aka malnutrition.

[@markcredit6086]

​@@lilydauber3147wrong what's wrong with you

[@chazwyman]

There are reagions in cities that are being called real food deserts. Places where it is impossible to buy real food. The only choices are fast food, and stores such as 7/11 which sell food-like substances, or factory produced edible material. They have in common high calorie density, hyper-palatability and addictiveness. And we wonder why there is an epidemic of obesity, T2D, NAFLD, and Alzheimers.

[@kellyabrahamson9139]

Spot on

[@keithdainton6043]

I am 70 years old i don't know any numbers i don't go to the doctors.what i do is eat mostly healthy.drink in moderation.i work out walk or cycle every where. and don't live in fear.

[@cabolynn]

I have just started to read Peter's new book and will have to read it in small increments, as there is so much to learn and take notes on. I'm 63 now and have watched all of my grandmothers, aunts and my mom, degenerate and have made a promise to myself to take care of my health. My 90 year old mother is currently in a hospice bed and has so many health problems. Watching her suffer has just made me even more grateful that I have taken the initiative to care for my own well being. Great interview with Peter and thank you.

[@scarface548]

I would like to have a long healthspan and look into ethunasia after healthspan ends

[@mariochan1415]

@@scarface548 nice one there mate

[@lilliangoertzel5609]

p

[@poerava]

Be careful there. Attia shares a lot of nonsense on many things.

[@mariochan1415]

@@poerava I'm 61 yrs old, high blood pressure, cholesterol, sugar, had all of it. By following his advises to the heart like fasting, eating the right kind of food and doing weight training ang cardio greatly improve my health.

[@lisataylor7516]

❤ this podcast!! 63 year old woman I’m good health and want to keep it that way. Take care and keep up your great work guys

[@mindbodygreen]

Thank you so much for listening!

[@dancassidy7471]

Thank you do much. 72 yrs old 12 years of triathlons and planning a comeback after covid twice and slowed motivation Retired RN 4 months ago.

[@hansschenker]

Great respect for Peter Attia's energy to spread the message. He is one of best sources for getting knowledge on healthy aging. Thank's a lot for publishing!

[@deliaocampo4340]

Dr.Attia so bright , truthful great wish all doctors like him who really cares ♥️🇸🇽🇺🇸

[@michaelcaragio8521]

Peter, I’ve been following your research and spreading the word to all my family members and friends I’m 68 I do 4 to 6 miles with my dog every day. One thing I done that helps me a lot is my morning water regiment, which includes pink Himalayan salt and electrolyte powder to keep me hydrated.

[@FindTheTRUTH337]

That’s fantastic. What’s the name of the electrolyte powder?

[@michaelcaragio8521]

Dr. Berg electrolyte powder, strawberry lemonade

[@mixalis6168]

My friend is 72 and his has been exercising all his life, can do the splits, high muscle mass, elite VO2 max, is on no meds. Eats 3 times daily clean and fresh food @

[@taraleightaracumming6726]

He’s the doctor we all need! No doctor I’ve ever had, had ever been anywhere near this level. We need better health care. We really need to be our own advocates. Doing our own research.😊

[@regalnut86]

YES! I am now doing that :)

[@samieramohamed2467]

93 in Iraqi stress is equal to 500 years. In the West .Dad , grandmother all died of old age not CvD, diabetes, but a surgeon brother studied lived worked in Germany died at 78 due to diabetes type 2 complications

[@zelmoziggy]

"Doing your own research" on the internet almost never ends well. 😆

[@samieramohamed2467]

@@zelmoziggy yes all focused on selling books supplements forgetting the root causes of the toxic environment in which we live.

[@dimitri9959]

Personal responsibility is the answer not “white coats.”

[@lanebrain55]

Social life and interactions are also a part of longevity

[@dagmarvandoren9364]

Yes. The good old days. Some vino. Some cafe. Good cake....somerimes a cognac for a birthday. All gone. Cell phones. Running. No vino no vino. No no...little cafe running. Cell phone. Working. Running...for 10 years more

[@susanvanheel4382]

You can say that exercise is most important, but I am in my late 60’s and have many friends in there 60-70’s who have exercised well, but end up with a knee, or hip, or shoulder replacements due to bad diet, ie SAD .

[@ramanandakamath6658]

O

[@MichaelNelson-tz2hv]

I'm a firm believer in intermittent fasting, long term (5-10 days) fasting and giving whole blood 3 times per year to improve heart and cardio health....

[@zibtihaj3213]

iving whole blood 3 times per year -- where is the proof that that works... ? pls reply

[@davidblackford5193]

All in all a good common sense summary of healthy living advice ...... Except.... Yes the Cholesterol Hypothesis to heart disease. Peter says he just doesn't get why more doctors don't support it so maybe this will help. 1. Statins reduce your risk of having a heart attack or stroke by an absolute 1% with all the side effects. (Blood glucose, CoQ10, Muscle soreness, increase in CAC and Lp(a)....) Why would you do this for 1% when you can get much more from other options and no side effects. 2. ApoB is not atherogenic, yes there are cholesterol crystals and ApoB particles in plaque along with a bunch of other stuff , the most dangerous being Apo(a) small and prone to oxidization, again Lp(a) didn't cause the problem in the artery but just their to help out. We didn't get born with our livers making a pathogenic molecule that penetrates perfectly healthy endothelial linings of arteries and in fact it's impossible for a molecule that size to get through a healthy endothelial layer , we were beautiful designed that way. The problem occurs when there is damage from - high blood pressure, smoking , oxidation, cocaine, inflammation, high sugar diets resulting insulin, anything that damages the endothelial layer. 2. We probably don't need Lp(a) as it's a bit of an ancestral hangover to assist clotting in the case we didn't have enough vitamin C in our diets. If you are going to eliminate something then at least take out the right molecule , Statins can actually increase Lp(a) which makes no sense at all and can make the situation worse. However after years of statins and billions of dollars it would be a very big person or company to come out and say we got it wrong. Anyway, hope that helps explain a couple of the reasons and would be great if Peter looked into this a bit more.

[@jeff911rn99]

Nailed it. Excellent.

[@billdublewhopper3064]

Carnivore diet for 10 years...gave me heart attack.

[@joenunez8202]

I agree, looking forward to reading your book, not being sarcastic.

[@MultiBlablabl]

With all due respect @David Blackford. Can you at least provide one study that supports your opinion? Let it be something else that Dr.Berg opinion because every Lipid PhDs/Experts support thesis that ApoB is atherogenic.

[@davidhogg1216]

Attia - ignore his nutrition advice. And there are dozens of longevity people out there that surpass his knowledge. He is too prone to going the Pharma route.

[@jerseyjim9092]

The studies are conflicting on many of these subjects and until theres convincing evidence, its best to take them with a grain of salt. Eat real food, get sufficient protein, stay active, maintain a healthy weight, and enjoy life. Stop worrying about minutia such as vo2max and exercising at some special zone. Is that really going to make a significant impact on your lifespan or healthspan? Where's the evidence?

[@kathya1956]

But Attia has to make a living.

[@PaulBurdo]

I don’t think we should worry either, and I’m not sure Dr. Attia is communicating worry. Perhaps an honest, a better, and a more respectful description would be with the word “concerned”, just as I am concerned about my O2 levels at night, considering how shallow I am breathing when I wake up, and how weak I feel until I get some deep breaths before I rise. Maybe my upcoming sleep study will reveal more. Proactive, purposeful, pursuit of progress can possibly preclude …worry.

[@adrianbelcourt9640]

Perhaps the reason he needs to be listened to is couched in your very very vague Rx … “… eat real food, get sufficient protein, stay active, maintain a healthy weight..” On how many level is this questionable advice .. according to this (your advice) my Mom, who takes no less than 5 medications is hitting your mark. And my second point: Once we see YOUR work, (until then be respectful while you sit in the stands and criticize, cast aspersions and dismiss away his efforts) we will respond in kind. He is making us and hopefully healthcare better … and you may, I think yes, sound exactly like those who disparage scientific and advancements throughout history. I look forward to seeing your book … and when I do, I’ll make sure to listen with an open ear.

[@lynnpep6962]

I downloaded “Outlive” so far I can’t stop reading it. Thank you for sharing all of this valuable information.

[@GregariousAntithesis]

Someday if we ever get past this healthcare for profit fiasco i predict they will look back at cholesterol as the cause of cardio vascular disease like how we look at using blood letting for illness. Its compete archaic junk science. Sugar habitually at high levels combined with standard systolic blood pressure causes the damage largely then the cholesterol has to habitually repair the damage until the artery is plugged. I think grain/seed is the primary food driving the majority of it. There is something inflamatory about grain/seed beyond the high glycemic nature which is also in other processed food/garbage. No animal was ever meant to eat grain all you have to do is look at how fat cows get in feed lots on grain. Additionally our dogs when fed the 70% grain based commercial doggie fast food get the same issues humans face, oral health issues, diabetes, cancer, obesity. Humans were eating primary animals before we invented agriculture. We supplemented we roots, tubers, etc and i realize its different in different places around the world. The point is no other animals are contending with health issues from diet becsuse they all eat whole food diets. The only time ruminants eat grain is in combination with the whole plant in nature. Hence why deer are lean not full of ectopic fat. So it makes zero sense eating animal products, one of natures whole foods would cause disease via cholestetol. Lions, etc circulation is saturated with cholesterol and they are not dealing with plugged arteries. Speaking of arteries, arteries are the only vessels damaged not capillaries or veins. If cholestetol were the mechanism for disease one would think veins and capillaries would also get damaged. Nothing about the cholestetol hypothesis makes sense. Yet habitually high blood glucose does because we can see the damage done to diabetics from habitually high blood sugar. Lastly the human body only has roughly 2000 calories/600 grams of glucose/glycogen storage in muscles and liver. We burn fat as out primary fuel source during rest and day to day activity. Only during high intensity activiy do we burn mostly glucose. Once we have our glycogen stores full from a high glycemic diet the liver then has to convert the remaining glucose into fat/triglycerides gor fuel or storage. Why would our primary fuel source fat, be the cause of disease. It should be pretty obvious by now that when you pour pure fuel sugar and oil, into a system designed for whole food. The liver becomes overwhelmed and the excess fat starts getting put ectopically in the liver and other organs, muscles. Because diabetes and other metabolic disorders arent glucose storage issues they are fat storage issues. Ectopic fat damages the organs and leads to metabolic dysfunction and that is the viscious cycle of metabolic disease. The processed grain and seed were invented by man and there is nothing natural about it.

[@karenmitchell4561]

I'm with you. Dr. Attia needs to rethink his hypothesis. Allopathic medicine has gone down a capitalistic rabbit hole, leaving us and the docs in quite a mess. But...thank God for the internet. With Google and the likes, we can learn the truth for ourselves.

[@talllala]

Sorry your comment is great but can you please clarify something for me?. You're saying excess sugar, glucose gets converted into fat. Is that correct? That makes a lot of sense and explains the sugar, grain, heart disease connection

[@GregariousAntithesis]

@@talllala yes it is absolutely true and so the traditional type 2 diabetes theory of insulin resistance in terms of the muscle and liver cells makes no sense. Once your glucose stores are full the liver has to convert the remaining glucose to triglycerides. Very minuscule glucose storage anywhere else besides the liver and muscles. It is why its important for metabolic health not to keep your glucose stores constantly full, i think that is part of the dysfunction. No one obviously knows exactly how it all happens but it is very obvious the habitual pouring of pure sugar and fat from grain and seed oils plus on top of that more fat from animal products all together over whelms the liver and digestive system leading to ectopic fat in organs and muscles. Why that happens is a good question because obviously the fat cells themselves become dysfunctional and that damages the liver leading to high blood glucose not because insulin isnt working. Only thing that makes sense about insulin sensetivity and resistance is that the hypothalamus and vagus nerve which sense glucose in the blood get desensitized and damaged from habitual high glucose and can no longer properly manage insulin if they cannot read glucose levels accurately. Obviously these are my laymans theories but they make far more sense than the medical and science communities explanations. Doesnt seem any of them payed attention in bio chem and metabolism classes because they are not seeing the interplay of the various parts.

[@zachnunya8749]

Really tough to answer the question of correlation vs causation concerning why strength and high vo2 max is so effective in promoting health span. (People that lift weights and do cardio consistently are gonna tend to be the type of people that also eat healthy).

[@selenekranz4061]

I’ve listened to many of Peter’s podcasts and subscribe to this channel. I’m grateful for the good insight I’ve received. Not trying to be a contrarian but I’m surprised that statins are looked on so favorably when they raise blood sugar - another significant risk factor for cvd. I’ve also heard that their absolute (as opposed to relative) risk reduction is minimal. I think our understanding of cholesterol and its sub components is an evolving science. I prefer to eat a healthy diet and control the factors I can without excessive testing and pharmaceutical intervention.

[@AnitaCorbett]

The effects of processed food that raises insulin which has a cascade effect on our other hormones such as thyroid and cortisol needs to be highlighted in this topic too Blood pressure to me is the canary in the coal mine for poor food choices and lack of movement I suppose there has to be a pharmaceutical response for people who are unwilling to do what is sensible

[@lukestanley1965]

I think hes arguing that modern statins are simply much better. He talks about how they used to have horrible side effects but modern statins have far fewer side effects. The figure he gives is that only 5% of people have any side effects.

[@selenekranz4061]

Respectfully, that’s a point I would debate. Even regarding newer options, statistics from pharmaceutical companies differ vastly from those of well credentialed physicians who continue to challenge statin efficacy. They also offer substantially different statistics related to adverse reactions. There’s still much to be learned. Many individuals who suffer heart attacks and strokes have normal lipid profiles.

[@dr.samierasadoonalhassani2669]

Agreed.A lot of change towards profit ,Sad conversion to advertising statins.Very pathetic.Statinblock enzymeQ 10 and lead to dementia andmuscle wasting.

[@zelmoziggy]

Where did you hear that their absolute (as opposed to relative) risk reduction is minimal?

[@TheyStoleMyHandleAgain]

Dr. KenDBarry has a lot of insights on some of this info. For longevity studies I had always found Durk Pearson's take on this issue to be enlightening. (Life Extension) I don't care for his hairdo, but he and Sandy Shaw have been studying this for a long time.

[@bethra.flowers]

Getting my protein, as a Vegan Female @ nearing 50 years old, is a challenge but now that I know what the facts are about my personal intake by using a tracking app (Cronometer), I am getting better at optimizing my diet. My main tactic is to add whole cooked soybeans to almost everything: smoothies, sauces, chili & soups, stir fry, even fruit salad, On top of all other protein sources. I now get at least 0.9 grams per pound and often 1.2 @ my 130 pound goal. + @ least 10 hrs of exercise per week unless extended fasting.

[@kylemansfield3630]

That’s a shame as it’s not only the protean that’s superior from Animals but more importantly FAT which of course makes your hormones and is insulation for your nervous system and your body can use as Fuel which Brain loves Keto wise but also there’s No such thing as Vegan collagen which keeps wrinkles at bay and helps so many functions in the body as it’s so prevalent and at your age and is diminishing every day 😢Not a great longevity diet unfortunately unless your doing Keto Vegan I would let it go and enjoy your vitality to a higher degree best to you

[@KJSvitko]

Doctors offices are too casual when taking blood pressure so accuracy suffers. You need to be sitting rested/relaxed for 5 minutes before taking blood pressure. You should not have just had coffee or caffeine in the past hour. You need to not talk or move while it is being taken. You should not have to go to the restroom. Holding your urine to relieve yourself will raise your blood pressure. Your blood pressure changes thru out the day and is impacted by stress levels. It is best to take your blood pressure at home at the same time every day under controlled circumstances and track the results. Too many people have white coat hypertension just from going to the doctors office. Those with hypertension should be encouraged to address this with life style changes along with medication if that does not work. Doctors offices should tell people that lowering their weight thru diet and exercise may have the same result or better than medications. Nutrition and exercise education should be the first option in treatment.

[@ericwhittington4133]

Kettlebell, mace and heavy club training is like the Swiss Army knife of fitness. Your gonna get strong and your cardio is going to vastly improve. Win, win.

[@dagmarvandoren9364]

And then you get hit by a truck

[@djolds1]

Enlightening, thank you. I have definitely been in the dietary-heavy camp for the last few years. Needs a reassessment.

[@nonfictionone]

I’m not understanding his take on vo2 max. According to what he says, elite endurance athletes should all live to 110. And they just don’t.

[@michaelmorton4104]

One could quibble with the details but at least keeping a good if not necessarily elite vo2 max seems like a good idea. My question is that it seems like his apoB recommendation of 30 seems a little arbitrarily low. I’m still trying to wrap myself around the seemingly extreme cholesterol lowering recommendations and whether there are unintended consequences of lowering cholesterol so low.

[@IAmTheEggMan111]

Studies are very clear that endurance athletes live longer than any other kind of athlete as well as longer than everyone else who isn’t an athlete

[@nick_stein]

Female and male US Olympic athletes live 5 years longer than their general population counterparts: a study of 8124 former US Olympians

[@nick_stein]

I would like to add its also the general health you experience while living. Being sick and feel shit from the last decades or travel the world and do cool stuff

[@juanloprada]

Most of them abandon the practice when they retire

[@mysterydiaz5302]

I’m a small 5’2 woman …70 years old with a small hands I’ve done plenty of farmers carries… it makes me so mad that I cannot do a pull up. Part of it is the size of my hand and the ability of my grip and I know part of it is my lats. I can hold a plank for two minutes with a 25 pound weight on my back. I can push and pull a 75 pound sled up and down the turf numerous times . I can (so far) leg press, 345 pounds. Frustrates me to no end that I cannot strengthen my grip enough to start being able to do pull ups

[@richw7721]

Assisted pull-ups are your best friend. Stretch a band across the safeties in a rack and step on it, work the safeties slowly down until you don’t need the band anymore. Grip should be no issue if you use a rack with good knurling.

[@YouTuber-ep5xx]

It seems strange to me that Attia so eagerly takes and recommends these meds - statins - that screw with the body. I would think that he'll likely one day see that as folly.

[@grochef]

Dr. Attia is very smart. There are many that disagree with LDL being bad, and many studies also agree that LDL does not cause atherosclerosis. One question no answered by Dr. Attia and others who consider LDL bad is: If LDL is so bad and causes clotting in arteries, why then does high LDL not cause clotting in veins? The concentration is the same, yet atherosclerosis does not occur in veins. The answer is quite beautifully explained by Dr. Malcom Kendrick. Do look him up.

[@richardmead4272]

What about LPa which attaches itself to LDL?

[@hikari8858]

Exactly. When will all this nonsesse about cholesterol or LDL or saturated fat being "bad" for health will stop? And I don't think Attia is smart or knowledgable (well, maybe in business/self-promotion). And, yes, listening to Dr. Malcom Kendrick or Dr. David Diamond would provide more accurate information.

[@grochef]

@@richardmead4272 Hi Richard. I do not know specifically about how that factors in. However, I believe that glycocalyx disruption and endothelial damage is still required to form the clot that causes the recruitment of LDL and endothelial progenitor cells (macrophages or new endothelium). Without the endothelial damage, there is no need to form an atherosclerotic clot.

[@AnitaCorbett]

I loved your comment on the bell curve Peter ! We are each of us such individual little chemical factories

[@marktapley7571]

Don’t get sidetracked by Attia’s claim about “life expectancy.” People are not generally living longer but rather the actual advancement has not been in medical care but in nutrition and sanitation. Look at the first presidents, Washington-67, would have almost certainly lived longer if not for doctors bleeding him to death, Adams-90, Jefferson-83, Madison 85 who smoked from 8 years old, Monroe-73, J.Q Adams-80, Jackson-78, Van Buren-79. There was no allopathic medicine or supplements. None of them weight lifted or did aerobic ex. Now in the U.S. the avg. life expectancy is going down every year. We now have a situation where for the first time in history pre teens and even elite athletes are dropping dead routinely which has never been heard of. And we all know the reason for it.

[@hikari8858]

Excellent post! I wish more people were cognizant of these facts. Unfortunately, people have been indoctrinated into believing falsehoods.

[@tandrichter]

The reason for it is the manic competitive pace induced stress, GMOs, bigger and bigger portions of hormone fed animal protein, pre-packaged food, no walking(no side walks), TV Dinners delivered, Mac Donald's , sodas and shakes. Your American diet. At the other extreme , equally manic, you've got Bryan Johnston.

[@lachlanbrown409]

Clotting was experienced in Europe...but the program continued😢.

[@MenalcasPowell]

also sugar, sugar, and high fructose corn syrup@@tandrichter

[@barnabasmuplang-nk4fp]

Thank you Dr Igudia for being the most trusted doctor among all, your professionalism was on a high standard, thank you for coming to help me out with my Type 2 Diabetes.

[@annebeck2208]

Sleep apnea...the craziest thing is that it was the end to any military career 25 years ago, but in the last 8 years, they have been asking and sending fit, "healthy" older military (mostly men) for sleep studies. They are finding many don't snore, but have sleep apnea, some related to burn pits, some around planes and some unrelated to military life. Now Cpaps are not unusual in the military and it doesn't end people's career.

[@selenekranz4061]

Searches of Dr, Robert Lustig and Dr. David Diamond(PhD) would be a good place to start. However, a search of “statins - relative vs. absolute risk” will yield an abundance of riveting discussions. Evaluating same with an open mind has provided me with a broad base of knowledge relative to diet, lifestyle, and supplements that resonate with me, and support my ongoing wellness journey.

[@bennguyen1313]

When first doing One-Meal-A-Day I'd get headaches, but eventually I could go longer without any headaches. I understand Peter does not agree with Dr. Satchin Panda on the auto/mitophagy benefits of TRF.. but I wonder if Peter sees ANY positive adaptations the body is making? Would have liked to have heard some blood panel specifics.. for example, I understand ApoB as low as possible, which Harvard's Peter Libby suggests to get ApoB that low (20-30 mg/dl), requires $500/month of Bempedoic Acid to inhibit the liver from synthesizing cholesterol. But to keep the kidney healthy by maintaining blood-pressure at 120/80 (Sprint Trial), via zone 2 exercise , Angiotensin II Receptor Blockers (ARBs)... what should one's cystatin-c levels look like? Hope to find a like-minded doctor nearby (National Lipid Association). Regarding the Maui-Nui-Venison and UCAN Gronola (super starch).. I understand that protein is a structural nutrient, while carbs/fats are energy nutrients.. but if aiming for 2g protein per pound of body weight (50g per serving, 3x a day) what should the composition of the protein look like? 8g leucine mtor stimulator, 8g lycine, 2g, mythenian (high in eggs )? How often should one get a DEXA's Almi Index test? Regarding how to read scientific literature, I recommend Peter's AMA 30 Ep188 where they talk about Layne Norton Reps , The Cochrane Collaboration / Quant Hedge fund , and Austin Bradford Hill's Criteria to determine causality for epidemiologic /observational/accidental studies. I like the 43m that Hippocrates did not say 'first do no harm' and that Lewy body is a cross from a movement disorder (like parkinsons) and a dementing disease (like Alzheimer).. any thoughts on Braak's hypothesis that the brain inflammation is a result of mis-folded proteins traveling from the gut to the brain via the vagus nerve? Regarding the 57m30s mark on cardio and strength (farmer carry 2min).. I recommend his interview on Tim Ferris at the 1h23m where they talk about Zone2-5 regimen. John Coxtolstoy!

[@carouseladventures2037]

I appreciate all your research. One area I have personally been working on for about 30 years is the effects of blood sugar with performance. I am a cyclist, swimming, climber, hiker. As a cyclist I have monitored my blood sugar throughout many long endurance rides. One thing I try to achieve is a relatively steady blood sugar reading. But I have noticed that when cycling up into the 80 to 85% effort I do much better when my blood sugar has been elevated. Normally I will induce the rise by eating 1/2 a banana or other simple sugar, not to exceed 11 grams. It’s ongoing work trying to get accurate results. I run on dual fuel fat/carbs and am trying to find a formula to apply to a mixed bag of cycling efforts. I hope you can direct me to some research in the field. Thanks, Charles Samson

[@trianglejudoclub5873]

Suggest listening to Prof Tim Noakes, Dr Paul Mason and also research health effects of long term elevated insulin.

[@carouseladventures2037]

Thanks I will check them out!

[@clivewells1736]

If you're serious go OMAD (one meal a day) eat then drink what you crave till you're full and then just have water till your fast break and repeat. After a month you'll notice your P.b's going up due to metabolic fasting mechanisms kicking in giving your body the call to clean house and repair damaged cells. It's magic called nature.

[@robertoperaza2683]

@23:40 - there's no such a thing as 'no side effects ' when taking a drug and or interfering with your natural body response

[@MichaelArguelles-wv5cq]

I reviewed the studies of pcsk9 inhibitor Repatha as my Dr wanted me to use it. Less number of side affects but 10 times worse side effects. Read and study

[@AlistairBalister]

Its my understanding of the avg age of death over a hundred years ago is wrong to say 40... because nearly 50% of children died before they made it to 5 and it knocks the average down falsely making it look like 40 was the average. If i go to graveyards in my city i can easily find so many graves from the 1800's with people who died in their 70's and higher. if there are 4 people and 2 die before 5 (since nearly half of all people did die before 5) then even if they made it to 75 years old the 2 that died early would knock that average down to 40.

[@nonfictionone]

Totally. Vaccines and antibiotics have played the biggest role in ‘extending life span’ because children aren’t dropping dead from infections and diseases. We should exclude ages under 20 and track median age at death. Not much change at all. The best thing you can do is choose genetically excellent parents.

[@talllala]

Yes this is true, my history teacher said people of the past had fairly decent life spans provided they survived childhood and child birth. It's when as you say, child mortality is added that the average life expectancy decreases.

[@AlistairBalister]

@@talllala It makes sense to me... I dont understand why these people who should know better keep propagating this myth that we are living longer now. Only thing different now from 100 years ago is what we are dying of. Now its heart disease and cancer thanks to government, food industry and pharmaceutical companies all being in bed with each other and lying to us about what is heathy to eat.

[@ihartsacto]

Good math insight!

[@mariasteeves6126]

Please help me to understand? I am a long distance runner and engage in every possible sport. However, my grip strength, when tested in my early 50’s was poor, along with a high fitness score on all other levels ( strength, fitness, endurance, weight etc…score was high). I do have “Raynauds” , which is a circulatory problem in hands and feet. I have always had cold hands and feet and bursting of vessels since my mid 30’s. My mother does have more complex vascular issues since her mid 60’s & now in her old age of 92. and my condition is more severe now at 63. I feel like there is something to this hand strength but would like more info. Please

[@Marx1963]

Dropped my total cholesterol and LDL levels 80 points in 8 weeks . Each now both in range . Stopped eating egg yolks - hence I was eating 10eggs a day . HDL 65 Triglycerides-45 stayed the same . My APO-b was was also checked -119 🤔 I’ll now check if that also dropped down . Hopefully 🤞 Outlive a must read - great information.

[@beardumaw24]

Higher LDL is not bad as long as you have healthy cholesterol markers, and are metabolically healthy. More importantly is keeping your HDL to Triglycerides level in a good ratio. In fact some new studies out are showing higher healthy LDL is protective and that it is in fact higher triglycerides with lower HDL that is indicative of heart disease. Eggs are very healthy, instead stop taking high amounts of whey or other added proteins cut your carbs and sugars as they cause high blood sugars and inflammation. I eat 4 to 5 eggs a day for years and my blood markers are all great.

[@Marx1963]

@@beardumaw24 i eat low low carb and no sugar . Whey protein in morning. Abundance of egg yolks was the culprit. I’ve done this before . Everyone’s different -i still do eggs but less . I will be getting Apo b retested this week - see if that dropped .

[@amigast9778]

Would love to know your upcoming results.

[@Marx1963]

@@amigast9778 will post

[@lynlawley8903]

God that's a lot why that many

[@24bellers20]

I’ve been hypertensive for 40 years but with a holter on the average is 118/75 over 24 hours. Beetroot juice drops mine 5 points. Probably because it raises my nitric oxide levels.

[@HB-yq8gy]

If I end up in the nursing home, I don’t want to have a longevity I rather die sooner than stuck in a nursing home for another 10 years.

[@bryantcofty2709]

I wish I could just hire Peter Attiia or someone moderately equivalent as my health coach. I work very hard to increase my healthspan and am in excellent condition in general but especially for a 58 year old but there's to much emerging science and to many variables to track and apply.

[@poerava]

Maybe listen to Bart Kay’s analysis of him. Attia is a charlatan who doesn’t really understand the science or what he speaks about.

[@bryantcofty2709]

@@poerava Really? He "seems" SO educated, knowledgeable and experienced in the 'science" of human physiology! I'll check it out. Thanks

[@bryantcofty2709]

@@poerava "Who" is your "go to" source on nutrition, training and increasing health span?

[@nonfictionone]

@@bryantcofty2709 mark Mattson

[@1xJOx1]

@@poerava 😂 you sound as credible as Bart Kay, not!

[@ogeoge6000]

The best explanation of cardiovascular deseise I've found so far is Dr Malcolm Kendrick's book "The Clot Thickens".

[@lindapestridge3073]

Thank you.

[@sirfrancisarthur]

The problem with most podcasts is that, how can I get these brands or methods in Europe? What would they be named or are they still not legal etc. Which makes it very difficult to hook up with those great advisors I see here.

[@mariomenezes1153]

Brilliant interview! Thank you!

[@beardumaw24]

I would listen to Dr Erick Westman before Dr Attia. Dr Westman has over 20 years working with ketogenic diet and heart disease.

[@cookinthekitchen]

I know Peter did a lot of work on insulin resistance but I am still confused by the 2 paradigms that contradict each other that clain to reverse insulin resistance.

[@selenekranz4061]

Thank you for your thoughtful response. Couldn’t agree more!

[@JD-bk6wj]

Pharmaceutical SCAM is dead on. Marketing VS. true studies, peer reviewed, and honest. A trust reset is grossly needed. Ethics and "do no harm" are essential.

[@lovepeace8918]

After watching this I am seriously considering going back on Pitavastatin and Zetia. I have about 6 bottles saved full of Zetia (ezetimibe), I had an endocrine doctor tell me my Cholesterol levels were way too low, because I was taking it and also taking Atorvastatin with it. Normally I have elevated cholesterol levels and low thyroid (being treated) Anyways she cancelled my prescription for Zetia, so screw her, I quit taking Atorvastatin it bothered my muscles, aches and pains in my shoulders neck, it was real. I eventually tried Rosuvastatin, and well I complained a little on that too, and got prescribed Pitavastatin and that one has no side effects, but I got really dizzy one night, and just stopped taking it, not sure if it had anything to do with my vertigo and confusion.

[@smcg246]

Question: If cholesterol is what repairs the damage to the arterial wall and we no longer have that cholesterol to repair the damage then will we not eventually have an aneurysm?

[@selma5885]

Struggling with high BP and my inability to tolerate thus far high BP meds. Diuretic made my blood sugar rise, low sodium and was up 4X/night with trips to the restroom/disrupted sleep. Lowest dose. Beta blockers have given me insomnia,and one gave me muscle weakness ( history of chronic illness, fibro/neuro symptoms and med sensitivity), lisinopril made me feel horrible/increased chronic illness symptoms, and now losartan gave me ankle swelling on long trip and long boat ride and makes me feel exhausted/not able to exercise as much or participate in life thus far. My BP is normal upon rising but gets high during day with life/anxiety and always extremely high in doctors office!

[@maplenook]

Try Carditone. And Alpha-Stim.

[@selma5885]

@@maplenook Itook Carditone for last 7 years. Did not really control it andnow it is much higher. I increased to 2 per day last year. Alpha-stim helps sleep right? not BP? Issue is I can't tolerate the meds. I was sleeping before.

[@kurtvega3053]

Jason, thx for asking the what does Peter do questions.

[@nandoluislopes]

I don´t Know. Of course tackling CVD would increase life span. But I think that the understanding of what is causing a general reduction in production of several molecules in the body is cornestone. Like blood flow tends to lower due to some sort of general problem and this causes organs and glands to start receiving less blood in an asymetrical way. And this causes then to reduce the production of molecules. Probably this theory is wrong but focusing in supplementation alone, despite being an advancement, don´t tackle a possible root cause. Blood unifies the whole body, so a disease started by it also would affect the whole body. Like aging

[@charlesweinberg9511]

The Hand Drives the Mind, The Ascent of Man!

[@landoishisname]

How come we don't see particular longevity increases in people who exercise though? Still dying at the same average ages. Obviously not arguing with the myriad health benefits of exercise

[@connorgray2896]

Not true, lots of studies showing they live longer than average.

[@rualablhor]

You are then blind

[@landoishisname]

@@connorgray2896 What I mean is, people who exercise might live to average 85 vs people who don't live to average 75, but is exercise helping people be centenarians? Obviously avoiding stroke/heart attack etc means you're going to live longer by avoiding (early) death, but are we expanding on the natural "limits"? The new oldest woman never worked a day in her life

[@LaneCodeRedCarnivore]

The longest lived creatures are turtles , they don't move unless they have to... 😂

[@nonfictionone]

@@LaneCodeRedCarnivore artic shark, forgotten it’s name 500’ish years

[@wmp3346]

10x is for everyday smokers , and also does not take into account other factors that may increase your chances

[@gabriellewilliamson5810]

Peter would you use Berbarine instead of PCSK9 inhibitor and your mild statin prevastastin why not berbarine?

[@anujkumarshukla3881]

In the end of the day everyone is selling tablets surgery and suppliment No one talks about the role of chemical free food and cleaning of body from inside on regular Basis

[@lynlawley8903]

So how would you do this

[@nonfictionone]

@@lynlawley8903 copy the other apes

[@nancym4049]

I am curious what you would say about the many people who are much younger than typical and in relatively good health as far as anyone knows that are dropping dead from heart attacks. We recently had a friend, 56 and healthy, die from a heart attack while out for his morning bike ride.

[@dbuzz8926]

My first question would be did they get the shot.

[@jackbuaer3828]

@@dbuzz8926 Or did he get covid. It's funny that people blame vaccines, but do not blame covid. They can both cause circulating blood levels of spike protein

[@snuder9832]

On a keto diet which I started several years ago, my HDL increased to 104 and my trig decreased to 64. I eat saturated fat which keeps me off the carbs. My LDL is high. TC high…300s. We’ll see . I will not go on statins. Those people who die from CVD and have lowered their TC, and those with high levels of cholesterol who live longer?

[@Ruouiji]

I’ve known people who did everything that was considered, or perceived to be wrong, healthwise, and lived well into their 90s, and I’ve known exercise and nutrition fanatics that died in their 40s. Everyone is different, and there is no cookie-cutter solution to longevity! I grew up across the street from a lady who chain-smoked, and drank sodas nonstop. She died at 93 case closed.

[@MrPerfume1979]

Dave feldman made an experiment of how exercise lowered LDL, which makes sense as the phospholids, cholesterol was used to build and repar muscle. And children might have low bcs of utilization? Also some animals would not do well with low cholesterol, like migrating birds and bears.

[@daviddelguercio8458]

I’m 37. I look thing and fit. ApoB 129, ldl 181. Been getting dizzy spells while exercising or on the daily. Xanax helps with it. I have bad anxiety. Don’t know if the symptoms are from anxiety or a health problem from cholesterol.

[@omerkhan3726]

Pl. kiss the chlostrol hoax goodbye & check your nutrient level. Pharma pays a lot of money to experts to keep the cholesterol hoax up

[@judylloyd7901]

I don't think we are overnourished. Overfed, definitely, to the point of obesity. But still malnourished, because we're eating foods that are high in calories while being very low in nutrients. (Which would be carbohydrates!)

[@ginanichols2395]

You lost me at Statins 😔

[@larryking4208]

You need to associate ApoB with level of metal toxicity at the cell/tissue level, mitochondria damage level and cell level bio-resonance where cell exchange of nutrients and waste is working effectively. Elements usually associated with fresh low level at babies. Sleep apnea is the imbalance between the sympathetic and non-sympathetic system. Gut health is key balance of bacteria in body metabolism. Protein imbalances are associated with liver toxicity and insulin load on liver and kidney where synthesis of vitamins and conversion of hormones, most important vit-D, are greatly affected.

[@tomm9584]

He mentioned the need for protein and actually high amounts of protein in the diet and if you compare this to the Blue Zone groups around the world who live to be 100 years old or more they typically have low protein in their diet or are all vegetarian. Can you explain this????

[@yehonatan2020]

Niacin can lower ApoB

[@henryw5762]

,went on Keto and my Triglycerides went low and HDL went higher! Eat a lot of saturated fats!

[@okiok2535]

And it's always about the host " what about a person like ME !! " This question comes up with this podcast always!! What about me !!! I , I and one more time I .

[@oxydoxxo]

Maybe you should start a podcast

[@60-Is-The-New-30]

At 49:32, Mr. Attia said people should eat 1.5 to 2 grams of protein per pound of body weight. There is no way that he is correct on this. He had to mean per kilo of body weight.

[@russroberts6825]

1.5-2g per kg of body weight.

[@JoeS97756]

I wondered the same thing, he was talking kilograms, then shifted to pounds.

[@60-Is-The-New-30]

@@JoeS97756 I think he just made a mistake with words there

[@60-Is-The-New-30]

@@russroberts6825 I agree. I think that's what he meant

[@davidduez9234]

Another way of thinking about it is 1 gram of protein per Lb of target body weight

[@anitagenovese562]

Reverse aging...I have studied it for 30 years. The Red Reishi is #1 and cold water bathing ranks a close second.

[@lanebrain55]

I have been saying a long time "exercise is the elixir of a long life"

[@grandpaseth3779]

Why does Attia say bempedoic acid has no side effects? Anyone can look up any of the clinical trials and see there are a host of potential adverse effects. Yea, they don't seem to cause the muscle related issues that statins can cause, but that's completely different from saying they have no side effects at all.

[@MrYorickJenkins]

I always get suspicious when people say with a complacent and patronising look "you cant discuss this because its a fact" . Said "fact" as often as not is in need of definition and scrutiny. For example, Attia's sweeping generalisation thrown in your face (you cant discuss this dude!!) as fact:: "its a fact if you smoke you have a ten times higher chance of getting lung cancer". FACT?? That statement is way too simple and superfiical to be a relaible fact. What does he mean by "smoke"? "Smoke what? Tobacco? Grass? Plenty of people smoke who don't touch nicotene. Smoke a pipe or cigars or cigarettes?? Quite a difference you know. Smoking with or without inhaling? Inhaling is way more damaging to the lungs thats common sense. Smoking HOW MUCH??? If Peter Attia is claiming smoking say one tobacco cigarette a day increases your chances of getting lung cancer ten fold, he's making a pretty extreme claim. Just from Peter Attia's opening statement we can see how glib, dogmatic and arrogant doctors are and how they pull out statistics to confront lesser mortals with, ignoring the variables and side skipping the fact that statistics can be very misleading. The moment they open their mouths many health professionals reveal how smug, superior to non professional mortals, and satisfied with themselves they are. This Peter Attia (M.D.! M.D.!) a Stanford educated God in white, is a good example.

[@DouglasKubler]

I was curious about venison stick. Found it - Fat 1g, Sugar 0g, Protein 9g. $102.00 for box of 24 -OMG

[@auctionmusic]

wow!....somebody actually saying that cardio fitness is necessary. I call the stationary recumbent bike the miracle machine as it exercises both your heart/lung and your legs (where most of your muscle mass is). I cross train between the bike and jogging/trail running. I'm 73 no meds never get tired.

[@Disirablepossessions]

What do I do at 81years having never been more active than walking.

[@hikari8858]

Exactly. I wish I could give you 100 likes.

[@ihartsacto]

Just keep walking. My parents and their friends mostly lived into their 90’s and none did strenuous exercise. Cut down on meat and animal products. Cut out free oils and use butter sparingly. Do eat fruit and vegetables in season and use frozen ones over canned. Don’t worry about eating a few starches. Personally I supplement ala Dr. Joel Wallach but I like the work of Dr. Essetlyn and Dr. John McDougall for diet advice. Best wishes. I hurt my knee over exercising and can barely walk so enjoy it and appreciate its safety. Being injured is dangerous.

[@nonfictionone]

There are some longevity scientists who would really disagree with peters protein intake. And peter is not a longevity scientist.

[@Utbmingo2018]

Yes, yes, and yes..but..bp does NOT decrease with weight loss for many folks with hypertension. That's a correlation popularly sited as a causation. The fat shaming misses the subtle, internal, nuanced affects coming from genetic shape and structure of cardiovascular systems. Understandable mistake because you can't see folks' insides with the naked eye, but a mistake nonetheless. If we start to train our biases and microscopes on the endothelium, we could assess what substances repair and renew the linings of our circulatory systems, including pharmaceuticals, vitamins, and herbs. Less self-absorption and more listening is needed.

[@Katana_00]

Im not buying what you’re selling

[@MrKahunadog]

Same size pump... why wouldn't weight loss add to efficiency

[@Utbmingo2018]

@@Katana_00 spare me. I’m a human being on a personal healing journey, not selling a damn thing.

[@Utbmingo2018]

@@MrKahunadog Some folks see benefit with 60+ lb weight loss going from fat to skinny, others see no bp lowering with 25lb weight loss going from overweight to marginally so. Thus, pipe size theory is a rudimentary conclusion at best. Factor in viscosity and learn more. Also forgot for a lot of same folks glucose and adrenal levels check out, so metabolism and hormones is a wash.

[@MrKahunadog]

@@Utbmingo2018we both understand bp is based on a number of factors

[@zbyszek2951]

I have been listening dr Attia with great pleasure for years, sucking his knowledge as calf suck the cow. But I do not know what to think now. One sentence, when he mention taking drug (statin) which mess and disrupt production of cholesterol precursor and precursor as well for Q10 and many important hormones), with the goal to decrease ApoB level (LDL), put a question mark on everything I learned from him. What is going on? Does he got some generous subsidium for his good word for statins? Or it is just brain fog - one of the common statin side effect.

[@bermo6066]

It could also be that you're wrong about the risk profile for statins.

[@johnsavage4786]

You need to listen to Prof Bart Kay relating to saturated fats and the importance of cholesterol. Follow a Carnivore diet and see new health emerge without any pharmaceutical drugs.

[@kevinred9023]

Bart Kay is the man!

[@johnsavage4786]

I fully agree,as soon as fruits and veg are recommended I switch off. I still have a couple of coffees per day but add glycine and new pollen feel great

[@patrycja2696]

100%! Carnivore diet is the best and optional for people.

[@patrycja2696]

​@@johnsavage4786 on carnivore two years. Was still having weak coffee one per day. But learned many times it's really no good. But I felt great so didn't see the problem. Then I went on lion diet for only 10 days then travelled to my parents and started having normal strength two coiffures per day. I feel horrible!!! Whole week. And it clicked. It must my that coffee. I feel on micro level shaky internally, negative thoughs, pounding heart, shallow breathing.... I feel like on microdose on amphetamine. I start to believe coffee is bad, just so so miniscule bad that noone noticing anything. I'll go three months no coiffure now and see what happens when reintroduce again. Chaffee has episode on coffee, Ploam I think on coffee and anxiety, another carnivore lady doctor but don't know her name - she says straight it's a poison...

[@jamesherried9269]

@@patrycja2696 No, humans are not carnivores, by nature. Humans are in the order of primates. And no primates are carnivores, by nature.

[@LeaPustetto]

I'm taking liposamal vitc daily. Is this the lipds your talking about. Dr Levy the vit c guru Is a proponent of liposomal vit c . Thankyou. Great interview. 👍

[@Baruch-Hashem]

Mortality is inevitable. All we have a statistical spectrum of behaviors that can guide people to longer lifespans. In view of eternity, life is but a flash. Is a long life better or is it that a healthier life is more meaningful should be the question. The most in my opion thing we can do is have children earlier and have more of them to give life more than materialistic purpose and a motivation to be around as long as possible. Starting after your career has progressed to have children, welll you can control is now and not the past. Materialism needs to take a back seat to health and family, we need to earn for survival, not meaningless stuff.

[@scotchbarrel4429]

Peter is the best longevity guru 👊😎

[@omshallom5521]

Brilliant interview, Great questions, almost read my mind and great responses, simple,. and informative. Thank you

[@bobtosi9346]

You’re right. There is no valid scientific evidence that shows and proves statins decreases all cause mortality.

[@lilydauber3147]

If you want to be the very best at whatever sports you are into, you can’t eat poorly. Junk food will derail you, which is why athletes only choose to eat badly after they’re done competing, whether it’s for the day, the season, or their career

[@ginacardarella]

Thank you what is APB

[@barrypenobscott9882]

At 49:32 I believe he meant 1.5 to 2 grams of protein per KILOGRAM of body weight.

[@jeff911rn99]

Does apoB really matter in the absence of inflammation, metabolic syndrome and high blood pressure?

[@aquamarine99911]

Maybe, maybe not. But when my ApoB hit 186 on a strict keto diet, I decided I didn't want to find out. My kids deserved a father. Someone else can self-test this issue. Changed diet (Mediterranean) and daily exercise brought it back to 83, while keeping excellent metabolic health and low (110/69) BP. and hsCRP.

[@jeff911rn99]

Well the Inuit eat high fat low carb and have low rates of heart disease and diabetes . My kids are grown, so I'll risk it 😏.

[@aquamarine99911]

@@jeff911rn99 Always happy when someone else is willing to be a guinea pig. Good luck! Look, Peter hints at it here when he mentions APOE4 status, but we're all different, and react differently to things like sat fat and dietary cholesterol. Lipidologist Thomas Dayspring talks about other factors that affect our individual tolerance for fats. I'm sure those Innu who couldn't handle a fat/carnivore diet simply died before reproducing, or kept walking down to Mexico 20,000 years ago.

[@embarq12]

I think Peter has mentioned once he does not know the answer to this question, but he also says inflammation is hard to measure. It takes decades for ASCVD to show up. So we won’t know for a while

[@kathrynderby4057]

@@jeff911rn99 Research done around 2015 and published in "Science" found that the Inuits have a genetic mutation that allows them to thrive on a high fat diet. I think the best bet is to eat like your ancestors.

[@carpediem9382]

Awesome. I will get the book.

[@daves1107]

Don't think I would hang my hat on Dr Attia's speculations. The basics appear to be exercise and a pharma drug approach. Hold the drugs for me, pharma drugs can't create health and always interfere. I appreciate pharma drugs when it comes to addressing fast death issues.

[@aquamarine99911]

The problem with meds is that they reduce your incentive to treat your body the way it seems to want to be treated. Pure diet and lifestyle changes took my ApoB from 186 on a strict keto diet down to 83 (high-legume Mediterranean). My astonished physician now says that's fine given my lack of other risk factors (BP of 110/69). Peter here is saying we should drive it below 80. Now I've added psyllium husk to try and get there.

[@daves1107]

@@aquamarine99911 Get the big idea and everything else will follow. Looks like you found it!

[@theasiandev]

"The basics appear to be exercise and pharma drug approach" -- this is misinterpreting him and not what Attia discusses in his book. his book actually does not discuss much about pharma approaches (only when necessary), but majority of the approaches is via lifestyle changes (exercise, sleep, nutrition).

[@paynelcasey]

Looked it up. Sounds like Mediterranean diet helps lower the ApoB.

[@ginacardarella]

Thank you for measuring that insurance doesn't help cover a lot of important tests

[@AnitaCorbett]

Blood pressure - for women the relationship between estrogen and progesterone

[@Crowmother13]

At around 23:00 dr attia names drugs but I cannot understand what he said after pcsk9 inhibitors. He spoke too quickly. Can someone please tell me what he said?

[@videoagogo1]

Ezetimibe & Bempedoic Acid

[@dwsolberg]

Not that I disagree on the conclusion, but the direction of causality isn't absolutely clear. A person with cancer on chemo isn't going to be exercising and they will loose muscle. Even at the low end, minor morbidities and pain make exercise and movement more difficult and less likely.

[@brady3474]

He is incorrect about muscular side effects affecting only 4%. It is way more than that.

[@carlosstafford8306]

Comment: what ever happened to factoring in HDL and triglyceride numbers in relationship to ApoB? What if HDL is high and triglycerides while ApoB high. Don’t they function holistically instead of analyzing one parameter only which is the rap on Western medicine