Monitoring dynamic changes in biomolecular condensates & LLPS

Prof. Dr. Tobias Madl talks about his research into biomolecular condensates, protein-protein and protein-ligand interactions and LLPS for improved drug discovery and drug targeting. He explains how he used the BRAVE B-Curious lab device to monitor his samples' behavior during early condensate formation for the very first time.
00:00 Doris preparing the device
00:22 Intro
00:52 Research challenges of Tobias Madl (1)
02:26 Early-stage condensate formation
02:42 Research challenges of Tobias Madl (2)
03:24 Aha moment with OF2i
04:07 RNA-mediated condensate formation
04:19 Aggregation processes (insulin)
05:07 How to operate the device
For more information, see www.braveanalytics.eu/en/of2i...
Prof. Dr. Tobias Madl spricht über seine Forschung zu biomolekularen Kondensaten, Protein-Protein- und Protein-Ligand-Interaktionen und LLPS für eine verbesserte Drug-Discovery und Drug-Targeting. Er erklärt, wie er das BRAVE B-Curious Laborgerät verwendet hat, um das Verhalten seiner Proben zum ersten Mal während der frühen Kondensatbildung zu beobachten.
Siehe auch: www.braveanalytics.eu/of2i/an...