I am SO GRATEFUL for this lesson. I'm an RN who recently switched to Oncology nursing a short while ago. I've scoured the internet and specifically KZbin for an adequate explanation of monoclonal antibodies. I have been unable to find one until encountering yours. Thank you, and keep up the good work!
@rutabatariq80964 жыл бұрын
I literally jumped up with joy upon seeing a video by AK Lectures on monoclonal antibodies!! THANK YOU SO MUCH FOR THIS.
@danstannevinsvansten63699 жыл бұрын
Wow! I love this lecture about turning normal cells into cancer cells for study..wish you could come over to The University of Nairobi for some lectures on Immunology..! This is a blessed effort sir.
@watjes8 жыл бұрын
this summarizes my 10+ page readings 👍🏻👍🏻👍🏻
@rhythmdew89285 жыл бұрын
He helps me more than any of my teachers . He is the literal definition of best!
@CHEESYhairyGASH8 жыл бұрын
You manage to consistently maintain the world's cleanest white board.
@austinvanderveer2137 жыл бұрын
that's not a green screen?
@raanoooshh92964 жыл бұрын
@Kolton Williams Same
@justinlane5963 Жыл бұрын
These videos never fail in making me understand topics. Never. Thank you
@9876jmlee Жыл бұрын
Even though I was majored in Biochemistry 20something years ago, I really forgot most of what I learned because I pursued organic chemistry in graduate school. Now I have to study biochem again because of my job and your lecture helped me alot. Thank u
@НаталияЛунева-г2я9 жыл бұрын
Thanks a lot for your videos! You are speaking quite clear so it is not really difficult to understand you for non-native speakers as I am) I hope I will learn a lot from your channel. I'm currently a 3rd year student of St.-Petersburg State Chemical-Pharmaceutical Academy, so your lectures are useful for my studies. Thanks again, keep going
@moribnd6 жыл бұрын
FFS, your video seems to be the only good one on monoclonal antibodies on youtube. Thank you.
@moribnd6 жыл бұрын
Would have been better if you described the screening process for the production of Abs of interest.
@ibrahimgomaa30518 жыл бұрын
انت رائع فى التدريس
@srinivasa.t.r99117 жыл бұрын
Very simplified explanation . Thank you.
@jonlin77047 жыл бұрын
Perfect layout, great explanation. Nice job dude.
@weronika6998 жыл бұрын
I love your lectures :) keep doing it!!!
@junz.57005 жыл бұрын
This is too good. Thank you!
@shaboatrad40667 жыл бұрын
It's an honor to write to you Cause you are really Awesome in teaching every single aspect and I gotta say if you wasn't I may have not been accepted to the Biology Olympiad So thank you soo much It will be Much more Awesome if We could have all (most)of ahat you said as a PDF or sth to print out and study and review.Every video takes me a lot to write down the most important things that need to be reviewed but all you say is to a large dgree important Thank you sooo much and I had a Question I'm a Biology Olympian and I wanted to know till this part of biochemistry is there any tests or Questions you suggest Cause I will only kearn and remember sth if I put it to work myself anything that I can somehow test my Understanding and See how much I remember Thank you sooooo much For your Awesome job
@tetrahydrocannabinol5863 Жыл бұрын
thank you very much sir. It is very helpful.
@ALifeWithoutReality9 жыл бұрын
Thank you for making this video. You explain it better than our teacher xD
@Fathimajr1197 жыл бұрын
splendid.nice explanation
@arsenalgoonerable7 жыл бұрын
Fabulous! Thank you!
@thea47759 жыл бұрын
Thank you sir :) Clearly explained!
@Shaurya00806 жыл бұрын
Well explained..!! Now I can write my exam ..😊
@netuchkanetuchka67333 жыл бұрын
Thank you - I still didn't understand one thing : after creating hybrid cancer-plasma cells, we still have a mixture of antibodies against different epitopes - how do you create monoclonal antibodies from the hybride cells ?
@zainabalwatheqi28188 жыл бұрын
Thanks alot ❤️ that will help me alot in my final exam
@hebahm16278 жыл бұрын
Thank u for helping me studying the exam 🙏🏽🙏🏽🙏🏽
@cjyoungmoreheadstateedu7 жыл бұрын
God Bless You!
@aniruddhg.r4 жыл бұрын
HAi sir!! During the mass production of the monoclonal antibodies, what is the process of removing the cancerous property from the plasma cells??
@dyoomah178 жыл бұрын
Great !! thank you so much .I have a question .. do you know how scientist use monoclonal antibodies in Prostate-specific Antigen test (PSA) if you know can you just briefly explain to me how ! ( I mean how they're using the antibodies to measure this antigen )
@smartgirls66148 жыл бұрын
thank you
@mhguevel20385 жыл бұрын
Thanks a lot. Merci
@Arti-pn8nu8 жыл бұрын
Your videos are awesome :) Keep it up!
@ryansabour9325 жыл бұрын
How did he screen the hybridomas for the select plasma cell?
@mashael19977 жыл бұрын
THANK YOU SO MUCH
@bastiwala08087 жыл бұрын
This video is not essential for learn to formation of mAbs becoz he did not explain the selective media and HGPRT knockout gene in Multiple Myloma cells. I think as per full understanding of hybridoma technology these things are very important for us.
@xinliu13377 жыл бұрын
Quick question, the hybridoma should have 4N chromosomes (2N from normal, 2N from tumor ), when these hybridoma mitosis, what will happen? Its progenitors will have 2N chromosomes? If so, if its progenitor split again, will it still have the ancestor all the hybridoma characteristics?
@ichsanhasyim50205 ай бұрын
Isn't that mean polyclonal just a bunch of monoclonal antibody?
@anindyachaturbedy75746 жыл бұрын
what are the screening methods?
@Pikachu-cj9oy2 жыл бұрын
Y can't you share notes sir....so it might helpful for many of us...
@silvercranium8 жыл бұрын
Sir, you said that plasma cells die on extracting from the body, so then how is it extracted and mixed with myeloma cells?
@aekkachaituekprakhonph.d.1738 жыл бұрын
What I understand is that, Plasma cell has short life span can not grow further for many passages. It doesn't mean plasma cell will die immediately
@ursilayaseen21368 жыл бұрын
Thankyou so very much for all your lectures... 😊
@meeromeer8812 Жыл бұрын
🙏
@JeanTeruo7 жыл бұрын
How you will isolate the plasma cells that produce the specific Igs? Put the antigen and test which bind in the antibodyies,? Ty
@derrickreuben56817 жыл бұрын
kindly read on the types of immunoassay and you will have the right answer with you. According to my perspective one can use the immunodiffusion test.
@mostafahamadi73649 жыл бұрын
thank you so muchhhhhh
@AKLECTURES9 жыл бұрын
mostafa hamadi you're welcome
@mostafahamadi73649 жыл бұрын
You having a Skype?
@AKLECTURES9 жыл бұрын
Yes.
@mostafahamadi73649 жыл бұрын
can you give it to me?
@AKLECTURES9 жыл бұрын
No I cant.
@steviemarkjones5 жыл бұрын
2:10 *hits that loud
@nikkileigh15852 жыл бұрын
So the jka antibody is a monoclonal antibody correct? I should've sold my placenta to science... the hospital probably did. Awe Jam it. 🤣
@shaboatrad40667 жыл бұрын
sry what happens when we frezze a Cancer cell?! it is still alive continues dividing but slower?!So we can have it anytime we needed it right?That's why we Freeze those Cancerous plasma Cells
@TheProdigalMeowMeowMeowReturns3 жыл бұрын
Don’t cough on your hand lol
@fohpono88843 жыл бұрын
After taking tons of Chemistry, Biology and Physics classes while attending college 50 years ago, I am drawn to your excellent lectures on a myriad of topics. You, sir, are an excellent instructor. Wish I had one like you those many years ago. I will watch every one of your videos just for the joy of it before dementia sets in.
@petermrwelson7 жыл бұрын
Hi, so can the monoclonal antibody be purified directly after extracted from the body (not the cells), the same as with polyclonal antibodies as you explained in the previous one? if not, why? Thanks
@anandk19774 жыл бұрын
If we have the sequence of the protein(the antibody), using a virus or some other method, inject the genetic sequence of the protein into any bacteria. Then the bacteria will produce these anibodies for us.
@cidiladms73459 жыл бұрын
please come to Sheffield Hallam University and be my lecturer!!! :) THANK YOU SO MUCHHHHH!
@AKLECTURES9 жыл бұрын
Daisy Bernini :-) I'd love to! and you're welcome, happy to help!
@leowaltzer1448 Жыл бұрын
Great video, thank you
@omarpalacios97348 жыл бұрын
Excelent videos, they have helped me alot!!! You have a a great talent of explaining ! Keep it up :)
@chhayapitre89978 жыл бұрын
THANKS SIR FOR YOUR VERY USEFUL LECTURES
@AKLECTURES8 жыл бұрын
+chhaya pitre welcome!
@matchmedicines82093 жыл бұрын
thanks for the nice explanation
@بشرىب-ث3ص5 жыл бұрын
Great explanation for the lecture you just save my exam thank you soooooo much
@hashinifernando41344 жыл бұрын
Explanations are very clear ..Thank youu
@maram51025 жыл бұрын
You summarized 30 heavy slides into 10 mints , thank you so much !
@Sam-fp8zm2 жыл бұрын
The body makes at least 10 to the 18 that is one quintillion or 1 million trillion different anti bodies.
@LiquidMetalLifeForm5 жыл бұрын
m the same guy whose ass was saved by you in Polyclonal Antibodies. :))
@godfreykamugisha40337 жыл бұрын
I always enjoy your presentation because it is understandable
@mollygillam6678 Жыл бұрын
Methodology used to create New Boston Virus ?
@nehamishra80762 жыл бұрын
I can't understand, because I am hindi
@wilbertsemeleer74806 жыл бұрын
Nice mouse drawing :D
@Lakshmi235Lakshmi Жыл бұрын
Thank you so much 🙏🙏🙏
@nxt58173 жыл бұрын
very poggour from france
@MrAlenita6 жыл бұрын
You are amazing
@thaddeusjudemassawa9156 жыл бұрын
great lecture
@LoganJarrell9 жыл бұрын
Loved these videos! Very helpful. The one thing I still can't understand are the applications of monoclonal antibodies vs. polyclonal.
@juanlugo74923 жыл бұрын
Wow fantastic job in simplifying this subject of Monoclonal treatment had no idea what great potential this treatment is this treatment will be a great revolution in medicine let’s hope it can help with Covid-19
@sonayaramber42654 жыл бұрын
Hello Sir, do you have Analytical lecture just like this? thank you. this is big help for self-review board exam 🤗
@ameyaathavale8013 жыл бұрын
Sir please can you make a video on phage display and yeast display technology for Monoclonal antibody production ?
@nadeemurrahman19428 жыл бұрын
thanks sir, ur every videos on any topic are very clear and I got it very easily. plz upload some lecture on digestive physiology.
@chaimaouaziz43364 жыл бұрын
you have a very good Pronunciation and explication thank you for this video 😍
@jenniferettinger49435 жыл бұрын
Everything you say makes it so much easier to understand. Its incredible!
@prashantkumar64449 жыл бұрын
thank you so much sir, nicely explained. and subscribed :)
@harryzhao1579 жыл бұрын
thanks!
@AKLECTURES9 жыл бұрын
Harry Zhao welcome Harry
@denishpatel40964 жыл бұрын
Nicely explained sir very helpful 👌 thank you 👍
@gimmichhetry70827 жыл бұрын
sir can u please tell me ..in mouse we inject a single type of epitope of antigen or multiple epitops