NAC: A Cancer causing Downfall?

[@mray3308]

I'm surprised that you didn't mention the dosage. Because most of these experiment tends to overdose mouse to get a result that mostly favor cancer which is the desired output for the research(!) Anyway, here is a comment written below the research page you provided: "In the study, they gave NAC in the drinking water at 40 mM concentration. An average mouse drinks 4 mL of water daily and the molecular weight of NAC is 163.19 g/mol. That means each mouse received a dose of (0.04 x 0.004 x 163.19) = 0.026 g NAC per day. An average mouse weighs 20 g, which means the daily dose was 1.3 g NAC per kg body weight. To estimate the human-equivalent dose, divide this number by 12.3. So, the estimated human-equivalent dose is 0.106 g NAC per kg body weight daily. In other words, 106 mg NAC per kg body weight daily. This ultimately means a daily dose of ~7400 mg NAC for a 70-kg human. This is an enormous dose! I take only 450 mg NAC once daily. Therefore, this article is totally irrelevant to my NAC supplementation."

[@Physionic]

Also true, but similar doses are used in animal studies indicating cancer and animal studies indicating protection from cancer. I’d also just wrap that up in the general critique of animal studies as a whole.

[@2BWiley2]

I would point out that the most-often cited recent study hailing the tremendous benefits of Glycine and NAC supplementation in older adults used as similar dose - 100 mg/kg/d - or about 7000mg for a 70-kg human. Additionally, this dose was maintained daily for 16 weeks (about 4 months). I'm 80-kg and often supplement 8-grams each of Glycine & NAC because of this study (albeit not every day). Is there even any benefit to only supplementing 450mg given that study, or is that possibly too low a dose to realize any real benefit? I honestly don't know, but here's the 2022 study I cite: pmc.ncbi.nlm.nih.gov/articles/PMC9879756/

[@CessnaPilot99]

​@@2BWiley2great point

[@mray3308]

Main reason for older people to take NAC is to compensate for the reduced Glutathion production. With this logic, any dosage that goes in to blood stream should have a positive effect on health if you have deficiency of that particular antioxidant. Taking a high dosage of any supplement is gambling IMO. So good luck to you.

[@MajorCanada]

I used to take 4000mg and developed a zinc deficiency. Back on it and I'm getting inflammatory responses. Weird.

[@tonywebb532]

I'm in my mid seventies and I have been taking NAC for 3 years now. It has cured my chronic sinusitis, asthma and has lowered my BP to normal levels. Dosage 600 mg per day. If I could only take one supplement this will be it.

[@Margo714P]

So, you only take one supplement then? If not, how can you know if this is the one that has fixed your problems?

[@lauraw.7008]

@@Margo714Pmy guess? Other supplements have been ongoing. NAC recently added.

[@DF-de8ib]

​@@Margo714P based on your assumption that he's taking only one supplement, uhmh uhmm ugggghh.....obviously? If he is taking only 1 supplement (NAC) and his health improved then what other supplements should we put the blame when in the first place there was only one? (which i assume he is taking others but when he added NAC that's when the change happened).

[@snave59]

I take NAC and Glycine.600 mg,twice a day of each.I never get sick.That is good enough for me.

[@futreno]

Tomo Nac 2 horas antes del desayuno para que no interfiera en la absorción de zinc y hierro y l lisina y me siento muy bien

[@LagMasterSam]

NAC is the best side-effect free thing I've found to eliminate my overwhelming brain fog and exhaustion. Even if it gives me cancer, I'll take it, because I would rather feel like a functional human for less time that feel like like a braindead zombie for a longer time.

[@Physionic]

Well, let’s hope there’s no cancer (seems that way, too). :)

[@thomcarr7021]

I'll take "brain fog" over cancer any day. I've never heard a good thing about chemo.

[@EHoser1]

Megadosing B1 (thiamine) stopped my brain fog. I always take NAC with glycine.

[@Margo714P]

@@thomcarr7021 Exactly. My sister had cancer. It was a horrible way to 'live' and die.

[@JMaxwell1000]

You would be singing a different tune if you were diagnosed with cancer, which is a terrifying prospect.

[@harold18659]

No matter the risk Glynac it is a lifesaver for me at 65. Makes me feel younger, stronger and took care of my COPD completely. I call it a miracle treatment.

[@patricialee76]

I doubt you're taking the ridiculous overdosages they used in these studies ;)

[@theancientsancients1769]

What dose of GlyNac do you take ? And what type of COPD do you have ? And if I may ask for how long or at what stage of COPD were you? Thanks

[@billshuey7422]

AGREE!

[@LincolnakaOnion]

That's amazing!

[@danielschuyler]

Where do you get yours? What brand?

[@romanr9977]

Thank you for adding the positive HUMAN study at 3:44. I also found a study in 2020 that trialled NAC on humans who currently had malignant tumours (breast cancer). It was given to them prior to undergoing surgery to remove the tumour and it found that the control group had their tumour REDUCE by 50%, whilst those taking the placebo had no change.

[@donnavincent2004]

NAC saved my health. When I was 60 I had pneumonia and was having a difficult time fully recovering afterward. I could hardly walk or function. Took Jarrow’s Sustain NAC and bounced back immediately!

[@buckw65]

I take 500mg / day and it's cut my asthma medication in half. Reducing the phlegm really makes the difference

[@arizonanative7409]

Wow… I live in a very polluted place and my respiratory system feels under attack daily. I have NAC, I’ll take it daily.

[@incognitotorpedo42]

NAC is used in the medical world to loosen mucus. I spent a month in the ICU with Legionnaire's disease followed by Acute Respiratory Distress Syndrome, and was given NAC along with a lot of very gnarly meds. Multiple doctors told me it was a miracle I survived. I've wondered for a long time if the antioxidant aspect of NAC is why I'm alive today.

[@buckw65]

@incognitotorpedo42 that's a cool that it helped so much. I'm very impressed and take it daily. At 500mg I'm sure it won't lead to cancer

[@dreamchaser6381]

@@incognitotorpedo42 I was in a same position too. We tried all the antibiotics including AVELOX and the only thing that cleared it was Azithromycin. And the next 30 days i used NAC with Erdostein. What kind of medication did they use in the IV bags?

[@ConniePretula]

I found NAC very beneficial when I had the Delta variant of covid. It is great for an antioxidant boost but it is also beneficial for the bronchial tube and lungs. I was amazed when I had covid and started taking it immediately, that my lungs and bronchial stayed clear. I take 500 mg daily during the winter season for extra support. Thank you Nic for the straightforward review. I appreciate your work 😊

[@TheFarmacySeedsNetwork]

Thanks for the update! Good info to be aware of! NAC has been VERY beneficial for me!

[@78Schack]

I’ve been taking GlyNAC for two years. Since I started, I have been completely free from asthma, which I have struggled with sine the age of ten (I’m now 46). My lung function is better than ever at the hospital tests - even though I have not been using my inhaler for a year (please don’t drop your medication without consulting your doctor first).

[@platos9054]

hi, do u take it on empty stomach or with food

[@78Schack]

@@platos9054 Yes, I take 600 milligrams NAC with milligrams 1000 glycine on an empty stomach in the morning, and the same in the evening before bed.

[@andrewromaro12]

This just reminded me of something! This book called “The 23 Former Doctor Truths by Lauren Clark”. My health shifted in a whole new way.

[@gsomethingsomething2658]

SPAM!!!

[@geraldfriend256]

No

[@PlatinumLemur]

I love NAC and now taking it together with Tyrosine for the last 2 weeks. NAC has helped my O2 levels right off the bat. Which was probably why it was a part of s commercial pre-work out supplement. I don't take it all the time but my husband was given NAC during his cancer treatments to help his healing process by allopathic practitioners.

[@og8425]

Thank you for providing content in areas where you'll receive a lot of pushback. Appreciate you following the data, keep the info coming!

[@ianhemingway5687]

There's been an odd push by the Machine to blacklist NAC in recent years (like when they tried to make it a prescription only drug). In which case, one can only assume that it is extremely beneficial with no down sides.

[@Jon.E.A]

..exactly! Been pondering the same.

[@deadhardy]

sure man

[@lauraw.7008]

🤔hmmm.

[@ubertrashcat]

What's the Machine?

[@aarondcmedia9585]

My immediate thought went there.

[@tkorte101]

I've started supplementing my senior dog with NAC, but also collagen so basically Gly-NAC. He has a significant heart murmur and NAC is a mucolytic, it thins the mucous, so it makes his cough much less severe. The cough is caused by backpressure on the lungs from the leaking heart valve, which pushes fluid from the bloodstream into the lungs faster than the lymphatic system can drain it. The collagen is also good for him in general as he is a senior and they can benefit from supplementation just like people do. But it's also 20% glycine so it also complements the NAC in that way.

[@rexleonis6943]

How do you determine the dosage for both?

[@darealrulezbreaker9493]

you said NAC+Colllagen is basicaly Gly-nac but isnt Glycene something completely different from collagen?

[@dreamchaser6381]

@@darealrulezbreaker9493 he doesn't know anything. Yes. Completely different.

[@willbrink]

I covered NAC and cancer connection on my YT channel a while ago based on a compelling study. It may accelerate some cancers, not seen evidence it causes cancers. I continue to take NAC.

[@Physionic]

Interesting - human research?

[@jrmint2]

I've heard the younger you are the faster cancer can spread too bc of the body's greater ability to manufacture new cells.

[@donaldkasper8346]

The presumption is all cancer grows linearly instead of fast/slow episodes. It also won't grow at the same rate across individuals.

[@meltedsnowman9637]

@@jrmint2 Cancer incidence correlates unbelievably highly with being older. Might be because your immune system is stronger when younger and can prevent the spread of cancer.

[@zekeriasvarg530]

@@meltedsnowman9637 cancer cause copper deficiency plus the others running dismutaz plus selenium,,, the fungus feels it and the microbacteria to,, they start oxidizing you and the higher REDOX tells your cells to start divide.. something like that.

[@casselskeep]

Antioxidants can prevent ROS damage and reduce cancer development risk. But antioxidants can also prevent your body from using ROS to destroy cancer cells that are already present. So... tricky

[@1969spp]

So biological too. Weird how little humanity has invested in basic research compared to other activities.

[@bogrunberger]

Both me and my wife take NAC, and my daughter at 15 also takes it because NAC has shown to have a benefit to people who suffer from OCD (she has trichotillomania). The more I read about NAC and its effect on the brain the more I want to take it.

[@TheCookiecupcakes]

Thank you Dr. ❤ Have a good holiday!

[@minimal9001]

The basis for looking at NAC risks is looking at Cysteine. Everyone will do better with glynac, since glyince balances out the inflammatory properties of Cysteine and methionine and also some forms of tryptophan. Most people would do better with more glycine.

[@EmilyJason-e1w]

Anything the FDA recommends, I now do the opposite. Health and Beauty Mastery by Julian Bannett is a must-read if you want to uncover the shocking realities of the health industry. It opened my eyes, and I’ve completely changed my lifestyle since!

[@FireOElijahMC]

i heard about that book before i might buy it now

[@geraldfriend256]

I bot it too, my fellow botflies.

[@FullGardenStudent]

scam comment.

[@alexandra.m.k]

Scam

[@aeonmancali]

@@FullGardenStudent Greetings comrade

[@edvedder7835]

Tiimely content. Thank you. NAC is given I.V. for Tylenol overdose in the ER. Liver saver. I should also add, that in the U.S. it's given like candy to those suffering pulmonary issues as well in an aerosolized form.

[@chrispompano]

Yehp , inhaled as MucoMist, as well as to protect kidneys from iodine contrast who have CKD.

[@reinerheiner1148]

There is a study on nac showing a correlation with increased risk of arthritis in humans. Yes, just a correlation, and I would not think much of it. But my personal experience is that it gives me joint pain. Which subsided after stopping NAC. I tried it secerap more times, and in my last trial, after being on it for a long time period, I became very prone to injury, with healing of tendon injuries severely slowed down. Its like my connective tissue almost stopped regenerating. After stopping NAC I finally start to see an acceleration in healing. Sadly, this supp is not for me. I suspect that it more potently than other antioxidants silences the signalling of oxidants to adapt to stressors, at least for my body.

[@jonny1943]

Interesting! Your comment gave me the thought to start writing every day about what i take and how i feel. Cheers!

[@yuguantan]

Combined NACwith glycine will prevent arthritis

[@laslo3714]

That's just my take but you should try taking Glycine + NAC. The reason is that Glutathione is synthezised out of Glycine and NAC. Notably, Glycine is also an integral component of collagen (connective tissue) synthesis, it's actually around 30% of collagen. So my hypothesis is, that you supplementing only NAC activates the synthesis of Glutathion and you being seemingly close to deficient in Glycine leads to most of your Glycine being used up in Glutathione synthesis. Therefore, supplementing Glycine could solve your issue.

[@user-lv9my6jw3x]

It's gives me, a family member and friend all joint pain. Sometimes severely. It's a bit of a shame since it changed my friend's life for the better (removed brain fog, increased concentration and emotional dysregulation amongst other things) and gave me a near 40% increase in testosterone! I'm around 900ng of testosterone and my free testosterone increased by the same proportion. My thyroid has also become a lot more efficient! I've been using it to combat mold illness.

[@user-lv9my6jw3x]

​@@laslo3714awesome tip and insight. I will experiment with this, thanks!

[@phantpwr]

I’ve been taking NAC for almost 5 years. (And glyNAC for a year) I recently got diagnosed with squamous cell skin cancer on my neck. I needed to get it surgically removed. I believe it’s correlated to NAC now.

[@missiontomuscle]

Love the channel. Keep up the great work.✊

[@Marlene612]

That bottle of NAC sat on my shelf for a while after I read or saw, and Im 75 so no idea where, that the body produces sufficient NAC for the Gluta conversion, and I wasn’t taking glysine at the time. Now I do both mainly hip hip hoorah due to your in-depth analysis. I’ve been doing sups for 55 yrs. Happy to say still learning from you. I’ll be doing NAC, lowered dose, to err on the side of caution bcz like all else with aging it’s all maintenance. Damn it. Love your work ✌🏻💙

[@lloydhlavac6807]

I'm 63 and have been taking 600mg of NAC daily for at least 5 years, so this was of great interest to me.

[@betterplacetobe7896]

Always learning from you 🙏

[@chasjeff]

Thanks Nick. Appreciate the update.

[@theancientsancients1769]

Cancer seems to be linked with everything! Some experts say glutathione itself even makes cancer worse if someone has it already, but for prevention it can be good. But I have seen Germans that helped cure some cancer with glutathione anecdotal

[@tenminutetokyo2643]

All things in moderation.

[@AarronS]

Working great for me. Herpes treatment. Haven't had a break out in three years.

[@GDe-gi1kz]

Bro what are the dose pls

[@lauraon]

Thanks Nic, interesting. It reminds me of when information came out that Beta Carotene supplementation was associated with higher lung cancer rates. That was the first I'd heard of antioxidants having that kind of effect. I had taken Beta Carotene, Vitamin C, other mixed carotenoids and other supplements for a chronic bronchitis/costochondritis/pleurisy (non-smoker btw). They actually worked, even though doctors couldn't help.

[@cajampa]

You missed the key about that beta carotene studies. They used synthetic beta carotene. As far as I know the natural substance was not correlated with higher cancer anything.

[@incognitotorpedo42]

@@cajampa Was it the same molecule? If it is, then I have a hard time believing that being "natural" makes a difference, and if it isn't, then one of them wasn't really beta carotene, unless the structure of beta carotene is undefined, which I doubt.

[@cajampa]

@@incognitotorpedo42 What are you talking about bro? You really doesn't understand these things at all do you. Instead of acting even more confused, do some proper research and realize I filled in a gap in your understanding. But you somehow don't get it. What I am telling you is really not anything strange or rare at all. Have you really never heard about how a synthetic version of a substance isn't the same as the real from nature stuff? You have a lot to learn because this is very basic stuff

[@cajampa]

@@incognitotorpedo42 I am going to give you two more extremely common examples to prove my point. What are the common types of vitamin E and C used in studies. And how much they differ from the optimal types and forms you can find in nature. If you know you know and if you don't you need to find out and stop acting like you have a clue what you are even talking about. Seriously......smh

[@lauraon]

@ wait, that’s an interesting point. I actually read about that (I’m not a scientist) several years ago before I learned how carefully you need to scrutinize the studies.

[@SlamminGraham]

I've noticed this trend where a lot of these currently-available anti-aging treatments will get accused of causing cancer, when after further investigation it is found that they do not cause cancer but rather cause existing cases of cancer to get worse. For years, the telomerase advocates had to fight those sort of accusations as well as the mTOR inhibitor advocates. It's tough when we just don't know yet and we want to be ultra-cautious about cancer, I understand. But obviously too much caution will unnecessarily scare people away from good innovations.

[@littlevoice_11]

It would be helpful to show the NAC clinically effective dose for benefits vs dose for risk. Then any overlap in the study doses. Perhaps in one of your helpful Physionics explainer graphs

[@Lightja_]

Thank you for your work. I'm a big fan.

[@paulman1970]

Could you do an entire video on the supposed anti-muscle building quality of anti-oxidants, as you have said.

[@pietercastelein2568]

Future research on supplements like NAC should explore the effects of dosing them infrequently, such as every other day or every third day.

[@lauraw.7008]

Woohoo! I’m the 1,000th like 🎉 ok. @ 70 I just recently (Nov2024) started taking NAC. Ya got me with the title! I will keep watching your videos & pay attention to future research context.

[@hfoxhaxfox1841]

Can you make a list of all your top supplements?

[@jeremywootten]

Great Vid

[@jamescondron8266]

Isn’t it also true that I alway take pause when cancer is being discussed, as is often the case and you mentioned the mice are bred with the specific genes that causes cancer they are not”rando” rats or mice from the barn, so in point of fact we are discussing potential increase in cell division not causation, or am on the wrong track?

[@agriperma]

Been taking nac for over a decade now, I only take a 0.6 to 1.2 grams a day, with glycine. It has helped with breathing as in I have no problems now. I'm 62 so doubt I am getting "too much" antioxidants. The idea is to supplement to bring levels up to where you would have them when young.

[@gr9939]

I have taken many supplements and never had a bad reaction. NAC gave me a migraine headache for a week and a half and weirdly, hallucinations that I was conscious of, I was consciously looking at the hallucinations. No amount of analgesics would stop the pain or hallucinations, but I figured a way to stop the pain and hallucinations, by taking something that crossed the blood-brain barrier.

[@stevealbenetyh38]

well, that explains my atypical week long migraine, thanks for the insight.

[@cryptomofo6619]

Good morning, Doc. Happy Thanksgiving!

[@Physionic]

Happy Thanksgiving!

[@cryptomofo6619]

@@Physionic Looking good- I'm gonna need a bicep workout video from you! 😉

[@sashaeffer]

During Covid the director of infectious diseases at UNMC(University of Nebraska Medical Center in Omaha) was on radio show talking about Covid. At the end of the show, he was asked a great question. Since he works with infectious diseases every day what does HE take to help protect him aside from the sanitary environment and physical barriers he wears. He said he takes 3 supplements. Vitamin B3, Zinc and NAC. He didn't mention dosages. While I knew about the first two, I never heard of NAC but could see benefits especially during Covid after doing a lot of research on it. Bought 1st bottle on Amazon, but when I went to buy it again it was no longer offered. Turns out the FDA pressured both Amazon and Ebay to NOT offer it on their site(in US). Many people doing their own research found out that it was also being used as a treatment for Covid(helping the lungs) Amazon complied but Ebay did not, so could still buy it there but it wasn't always available because of demand. My daughter stationed in Japan at the time could still buy it there through Amazon. It was amazing to me that the Government went out of their way to block treatments to help people with Covid. After Covid, NAC can now easily be bought on Amazon and I have been taking recommended daily dose. It also has Selenium which is recommended.

[@chrispompano]

Maybe Astaxanthin can be a safer & more potent way to resolve ROS & OS. The Japanese scientists think so & are reversing heart failure & liver failure. See video titled : Medical Frontiers Astaxanthin The Color of Health. Would loved to hear your thoughts.

[@elahau3783]

NAC was the only thing to stop my COVID cough

[@Artcore103]

NAC is useful at any age when you're dealing with some respiratory sickness.

[@rickt10]

Ahhh, to be a mouse. We know so much.

[@Margo714P]

🐭

[@tomp3960]

I posted the link to the CNN article about Nac and cancer in mice I'm a interested supplement user without a medical background . The thing that bothered me was the increase in lung tumors in non-human knockouts, ie normal mice. However as another commenter noted the equivalent human NAC dose is quite high compared to "normal: dose.

[@tomp3960]

Sorry my phone changed the text I meant increase in non-Jun d knockouts

[@jeffhutjens]

Inflammation is a trigger to cause apoptosis in dysfunctional cells. Lowering inflammation can aid, save or prolong the life of dysfunctional cells. This is why you take breaks from supps and practises that quell inflammation.

[@LoamReaper]

Thanks for covering this! I just started taking glyNAC (at 64) last week and I'm really hoping for some positive results.

[@simonleland2873]

the combination of MSM [Methylsulfonylmethane] and NAC really seem to calm my autoimmune responses.

[@davidnorman6348]

Thanks for that, Physionic! The theme caught my eye because as an allergy patient I sometimes take ACC (as it's called here in Germany) to loosen up lung mucus in the pollen season. My take is that I can continue using sporadically during the spring and early summer without too much concern, even though I'm 70. I have heard that NAC is useful in treating overdoses of Ibuprofen. Big fan of your site and particularly your advocation of muscle strength. Excellent work - keep it up!

[@theancientsancients1769]

Ja, but ACC powdered products in Germany contain lots of artificial sweetners linked with cancer . Get rather in capsule form . Best wishes

[@thomasmuller1850]

To play it safe, you could take whey powder rich in cysteine. The powder was able to raise glutathion in trials ("Open-labeled pilot study of cysteine-rich whey protein isolate supplementation for nonalcoholic steatohepatitis patients")

[@livephysiology]

It's also important to point out that some free radicals are needed for proper immune function. If antioxidants wiped out every free radical in the human body, it would inhibit the ability of the immune system to kill cancer.

[@maarten7]

Whew!! 😅 Thanks, Nic. Happy Thanksgiving. 🦃🥧

[@MikeG-js1jt]

Thanks for deciding to put this out there! .................... considering the circumstance where an over abundance of antioxidants (many of which can also have an effect in inflammation) can degrade health by disrupting the redox balance among other issues, is it also solid to consider the fact of inflammaging, where maybe an older adult would benefit from increased exogenous antioxidants/ant-inflammatory supplements, as opposed to younger folks whom it may harm?

[@fishnlady]

Very interesting. Thank you.

[@johnsharnetsky9559]

You got to factor in age. Oxidative damage becomes prevalent as we get older because our bodies can't keep up with ROS production because of wear and tear overtime. The body is pretty good about not over producing antioxidants but needs help as we get older for healthy aging. If everyone kept the balance of ROS and antioxidants as we get older there should be a drop in just about all common diseases, including cancer.

[@andreac5152]

As you said, it only restores physiologic glutathione if it's low, that's why it shouldn't overload the antioxidant system like other harmful antioxidants.

[@kinpatu]

I'm very thankful to have found your channel this year. Great work as always.

[@Physionic]

Thankful you’re here - thanks!

[@psylinx]

My knack cells are doing fine. Thank you for asking. George Davis

[@DCGreenZone]

Leukemia cells use GSH to protect themselves, but, not everyone is a leukemic. I believe an increase in GSH is almost always a win win.

[@user-iy4uf7ub2e]

Surely it can't cause cancer any worse than nitrates in my sausage biscuits

[@seahog32]

Probably not but does the risk go up if you combine them?

[@MaxCaud]

This is a dangerous comment, totally different mechanism. NAC could be worse, everything in moderation applies to even antioxidants.

[@user-iy4uf7ub2e]

@@seahog32 well that's just crazy talk. 😆

[@redicej5843]

Nitrates don´t cause cancer. Dr Berry has some vid´s on it

[@pixiesprite9433]

Please look into data and learn how to read it KZbin ' "Drs" should never be where you base your decisions off of.

[@napaman2104]

So I recently bought a bottle of NAC that was in a capsule with a list of other supplements. A recent MRI of my prostate gave me a PI-RADS 4 rating which means I have about a 50% chance of having some type of Prostate Cancer. Holding off on the biopsy for now. But when I saw it contained glutathione it rang a bell regarding glutamine and it being one of the 2 main fuels that cancer cells need to survive. Glucose being the other as per Professor Thomas Seyfried and others. In the meantime I was strongly advised that until a biopsy confirms cancer or not to definitely avoid NAC for now which I am. I'm 68 yo btw. Nick could you do a Video on Choline in eggs and it's possible effect on prostate cancer in particular? Thank you

[@michaelbradley7704]

Zinc

[@donaldkasper8346]

Prostate "cancer" tests are more error than data, be very careful. Also the cancer grows real slow, so may be better to die in two decades from it than have a serious decline in quality of life removing the prostate. No prostate is drip, drip, drip urine bag.

[@carlr2837]

I know that glycine is a fuel for prostate cancer, but I've not heard that about NAC. Note that glycine is commonly found in large amounts in meat, so that's possibly why vegetarian diets are correlated with slower prostate cancer growth.

[@danielschuyler]

Where did you buy yours? What brand?

[@zekeriasvarg530]

@@michaelbradley7704 boric acid some gram a day in mouth and into the prostate plus level up the copper. Iodine selenium and no cancer any more.

[@mrcadoia]

Glynac and ALA has changed my life at 53. I drink these powders during the day in a bottle every day. If you want to love your liver especially, do this.

[@UnknownUser-sc6jx]

The 2021 💉 is a much more concerning risk for cancer then NAC. Cancer for the most part are metabolic and life style issues.

[@viking933]

Not really. i am from China and here WE See high cancer Rates in people WHO didnt get the shot but Had the Virus . Kaposi sarcom, ( with AIDS was the Same) many Chinese studies are Out there.... The people WHO get the shot but Had the Virus dont .. so what do you think...

[@shirubaseishin3065]

I didn’t know this community harbored the crazies.

[@Mate-it1zt]

​@@shirubaseishin3065Yet here you are

[@marcosulima1627]

vide Thomas N. Seyfried - Cancer as a Metabolic Disease.

[@TheDionysianFields]

Quit taking NAC several years ago after reading some disturbing reports.

[@sue5158]

My 30 yr old daughter has episodic ataxia 2 with degeneration of brain cells. I was told shed be incapacitated by 60. There is no cure or good treatment. I just ordered her glycine and nac hoping itll reduce her oxidative stress and save some brain cells. Im hoping.

[@Midger24]

Have you looked at the (possible) benefits of hyperbaric oxygen therapy (HBOT) for her? I am not familiar with episodic ataxia but HBOT has shown promise for a wide variety of medical issues.

[@tenminutetokyo2643]

Long exercise both clears the brain of toxins and increases regeneration. 3 hours daily. Plus cleaning eating and reading, music, and other attention based activities have been shown to regenerate brain cells. Worth a try. Neck issues can also play a role as neck anomalies have been shown to prevent proper CSF drainage at night, leading to “brain toilet” effect.

[@mattermat1925]

The diagram at 0:34 is a bit misleading, as it suggest NAC turns into Glu, but "Glu" is the abbreviation for glutamate, not glutathione. Glutathione would be GSH. On the other hand, when synthesizing GSH, the first step is joining Glu to Cys, so Glu is involved.

[@GDe-gi1kz]

Atleast someone made a video

[@thomasanderson27]

Thanks for this Doc. I use NAC for its mucolytic properties as I suffer from blocked ears whenever I get any respiratory infections. I have been taking it for 2 years now with no side effects (1gram per day in the morning). I am 47 years old and started taking it continuously at 45. Prior to that I only used it as treatment for blocked ear but at 45 it just made more sense to make one of my permanent supplement.

[@DesertDog8989]

I've noticed that sites that track and involve the audience in their subscriber to viewer ratio, asking for more subs and shares with weekly updates to progress, seem to pump really well. You deserve at least 1M followers. "I've noticed that only 53% of regular viewers are subscribers, so if you value this content, please subscribe to get that number up to our goal of 56%" (or whatever your numbers are)

[@Physionic]

Thank you - I appreciate the kind words. The thing is - I already have trouble fitting all the information into shorter formats; I even cut 80% of the data because it simply doesn't fit, so me adding more calls to action just takes time and it doesn't add much. Sure, I get more subs, but if a person likes me, they'll know to subscribe - I don't feel the need to convince them or remind them. Either way, I deeply appreciate the support up to now, and if it takes me 10 more years to reach 1 Mill, then so be it - slow and steady :)

[@DesertDog8989]

@Physionic 🤩🤠🤩

[@lagianna100]

In the last few years they have tried so hard to demonize Nac. That is pretty telling

[@saga3668]

🎯

[@JoshuaH94]

Who is “they”? This mindset there’s some big bag group of people who want ‘you’ to suffer is such a poor black and white mindset. Any drug that that is “effective” will have some form of side effect, which ALWAYS needs to be considered. To believe we can consume every drug risk free is fantasy thought for people who don’t understand statistics and pharmacology.

[@spirit_geek]

Would the same be for glyNAC?

[@bartb1014]

Love NAC

[@m.bird.]

Anything that supresses inflammation increases some cancers. That's why it should be taken occasionally for short term.

[@Margo714P]

This is one of the central supplements that Bryan Johnson sells in his Blueprint products. This is my main gripe with his stuff. It's a one size fits all, and a lot of it really is unnecessary for younger people.

[@kathb1683]

Wish there were lab tests that could check for cancer or increased cancer forming in cells!

[@Jake-n1h]

Whey protein naturally contains BOTH cysteine and glycine, so if you are consuming sufficient whey protein in your diet, you likely DO NOT need to supplement with separate cysteine or glycine supplements as it already provides these amino acids.

[@tudogeo7061]

Is this the same as with eggs and heart attacks?

[@ljessel6612]

Did we have dosage? Some tests have dosages higher than human usage.

[@KatSchlitz]

1.3 grams per kg body weight, incredibly high

[@daniel.marbach]

Definitely not in the age group to benefit from NAC but I must say I get less drunk and have less hangover when supplementing NAC and overall I think I'm more resistant during winter time against respiratory issues or get out of it quicker. Have been doing NAC for two years in cycles for several weeks and while I have no data to proof things the risk / reward / cost ratio seems optimal for me

[@jp7357]

I've been taking NAC for years as part of my 30 supplement stack and for me, I can say NONE of these supplements has made me "feel" any different. I've stopped the stack for months on end, stopped individual items for weeks on end - and "feel" absolutely no difference. Even NMN .. nada .. no super human feats of strengths and my hair is stubbornly still gray (I'm 66yo). I AM in great condition - so maybe - something is working.

[@Midger24]

May I ask what your stack is?

[@sphires]

I only take Gly+NAC on signs of stress, illness etc. when Glutathione levels plummet. I also try to avoid it before periods of elevated blood pressure like workouts, and running due to studies showing it can cause damage to the smallest blood vessels during elevated blood pressure.

[@ashleylala4293]

Brett Weinstein’s research on wistar lab rat telomeres seems like it might be a relevant factor here.

[@beslemeto]

I don't think it is necessary to take NAC everyday. Twice a week or thrice is more than enough in my opinion...

[@brauliobo]

it is the same as glutamine, also a component of glutatione. it is great unless you have cancer

[@ruud4508]

Mice were exposed to high levels of radiation and they forgot to mention? Btw, where is that allulose that's a perfect table sugar replacement? I can only get it in Wageningen, the Netherlands. Or pay for it through the nose on Amazon. That would bring down cancer by a substantial margin. And it has no calories.

[@rehgaalkane8518]

Is it possible to have a video on carnitine ? Pls

[@jimb3457]

GLYCINE and NAC are molecules that our bodies slowly cease to produce around the age of 45. It is critical in completing the kreb cycle, in producing the master antioxidant glutathione. To the best of my knowledge, NAC does not cause cancer. Now if you already have cancer, NAC can induce ROS (reactive oxygen species) in some cells such as human leukemia, lung or pancreatic cancer. This can accelerate cancer growth. If you're not at least 45, you have no need for these supplements, but I believe they are critical for older and especially elderly individuals who are known not to have cancer. As with any supplement, it is up to the individual.

[@mtolives]

My experience with glynac is that it knocks me out whenever I take it. I moved it to 10pm. Did anyone else experience this "side effect"?

[@DBMMMMM]

What about benefit/risk vs. intermittent intake or dosage? Could it be related to other markers like consumption of of carbs etc etc

[@edl653]

I would expect that NAC/GLYNAC as it reduces oxidative stress effects it would include indirect protect against cancer. However, that protection would also protect cancer cells, hence an associated faster growth rate. I would suggest anyone diagnosed with cancer stop taking NAC, otherwise it is fine for folks over 50. My two cents.

[@nebojsa1976]

Here is my 4 cents, everyone is repeating this same thing: If you have cancer, don't go on antioxidants. But, the simplest question that no one asks is, how do you know if you have cancer??? It can be decades before cancer shows up.

[@edl653]

@@nebojsa1976 100% correct. First step is folks should get routine check-ups with their doctor and ask for age related screening such as for breast, prostate and colon cancers. Also, there are several public and private institution developing multi-cancer early detection blood-based tests. Hopefully they will prove to be effective and become routine testing in the near future.

[@jimb3457]

@@nebojsa1976 It usually shows up in a blood test. A blood test can help indicate the possibility of cancer, but it usually can't diagnose cancer on its own. Blood tests are often used in conjunction with other tests, such as biopsies and imaging, to help diagnose cancer.

[@nebojsa1976]

@@jimb3457 You didn't understand. Mostly every person will not do that. Maybe 5%. That's the main issue. Majority of people will not know it.

[@jimb3457]

@@nebojsa1976 If you're not seeing your practitioner on a regular basis for a checkup and necessary test and not getting your blood tested, you're rolling the dice. Waiting until serious symptoms develop can result in death. Early diagnosis is the key........

[@catitude4]

Just because someone calls it a study doesn't make it true. Who paid for the study, what is the agenda? Often studies are swayed to get the results they are looking for rather than truth.

[@andrewtaylor9799]

NAC strengthens the immune response; specifically Th17 immune system cells are able to continue action which would have been diminished due to oxidative stress. NAC limits the oxidative stress. This is usually fine EXCEPT if you have an autoimmune attack. In that case, NAC allows an autoimmune attack to be prolonged and more serious than it would be otherwise.

[@James-mh8zd]

Good morning

[@tkorte101]

Interesting and we'll balanced video. As for NAC being superfluous in people under 50, perhaps you're missing something. As the saying goes, and ounce of prevention is worth a pound of cure. If younger people were to employ NAC, perhaps that would delay and also significantly reduce the effects of aging, so not seeing any results would basically mean it's doing what it's supposed to and preventing things from changing. Whereas with older people, using NAC shows results because there are things that need to be corrected. I haven't seen your earlier videos on NAC because I'm a more recent subscriber, so perhaps you've covered this point there.

[@Midger24]

I absolutely believe younger people can benefit from NAC. I used it to avoid perinatal and postpartum depression. In the two years I took it I also avoided my usual allergies and didn’t come down with flu or anything serious. A single day of being sick with a non respiratory illness in that two year period. I actually learned about its use for preventing postpartum depression from my sister in-law that used it herself in her second pregnancy to prevent postpartum depression. Anyhoo just agreeing that younger than 50 can definitely benefit. Be it long term or for shorter term things like respiratory issues or allergy season. I took mine with a couple servings of collagen peptides (glycine rich). Definitely can be super helpful.

[@terrydevaney8601]

With any supp... The Dosage is in the posien