Pharmacokinetics | Drug Excretion

[@ФатмаКойун]

I can study from books, notes etc but none of them motivates me as much as your videos Zachary and the only reason for this is your pure passion for being a doctor. I hope that nobody dies before they discover their passion because there is nothing more joyful than doing the job that sets your soul on fire

[@alsharabyalsharaby1483]

Before I watch your video , I know surly ,it's a great explaining , keep going please talking about pharmacology stuff, Thanks for your effort

[@LA-ug6ol]

visual learners cant be more lucky with nenja nerd !! Well explained ,Thank you so much for this great work ❤️

[@mohammedisak4645]

Masha Allah I'm from Somalia🇸🇴 We proud of You Me and My friends For your Hardworking Thank you For Your Helping us With Out you I'm sure that i can't know something About Medicine. Thank you.

[@Kyle0714]

best teacher ever Zach. I love how simply you can explain the acid base & alkalization of urine to excrete drug metabolites

[@fightersoul6436]

Just beautifully explained ......hats off....the topic which I couldn't even start.. seeing the complexity of words ...this person not only explained it awesomely but explained it in a way that I will never forget the concept in life!❤️

[@cristianxavier5954]

just started taking Pharmacology classes and you have just saved me!!

[@OmarFatimaZohra]

Best explained videos ever ! I'm amazed by how much you can simplify the concepts honestly thank you so much

[@yogireddy7209]

You have cleared all of my confusions about this drug excretions thank you so much 😊🎉

[@taima899]

*******Just wonderful, I had all these concepts scrambled in my head until I watched these lectures.

[@22.Satty.]

You make learning joyful sir it's the best thing about your teaching I am forever grateful 🙏

[@Timtam973]

Another very helpful video! Thank you Zach!

[@Fifa_sajad]

I have never seen such simplicity . Thanks for everything ❤

[@doc_matox]

Best KZbin tutor ever❤❤❤

[@Farxiya-fc1jf]

You saved my grades so many times that I can't thank you enough ❤

[@mamalyfarahmand592]

when chemisrty plays an important role in clinical practice thanks Dr. Murphy

[@andrimartomasson5256]

Thank you mr. Ninjanerd Sir. I have been leaning on my good friend and mentor, Vás, this semester. However, there are even gaps in his knowledge, as pharmacology is such a vast and complicated subject. You fill these gaps beautifully. May God bless you and the Ninjanerd team.

[@gowharmajeed2329]

You are best teacher in world

[@remembermabasa2247]

Thank you very much for this content.. I'm really enjoying and learning alot from these videos. Best teacher, everything make sense now.. Thank you prof

[@kayanbsoul7483]

Just wanted to say a sincere thank you :)

[@samehabdel-hakam2026]

Dude! your videos are so damn underrated!! there should be millions of views! Wish those were available back when i was in college.

[@tanyagupta1509]

Tysm ninja nerd for explaining the concept it's great😃👍. Kindly keep going with pharmacology topics.

[@francesca_rahkolli]

Thank you for this! I'm learning a lot from you..

[@HeiSoGzY]

Ninja Thanks for Helping us break each and every Topic Down I'm Favour a Pharm D Student and a Very big fan of you, I just need only your videos and your videos Alone to understand any confusing Topic, Pls can you help us on Pharmacokinetics; the distribution part. Thank you Ninja nerd, we would really Appreciate it.

[@invisibleblack7597]

Much love from Tanzania❤️

[@rayanthabit3489]

So so so exciting while watching..I hope pass the exam today BTW who is arabic here ?

[@miranabubakr5844]

You drop this 👑

[@khalilahd.]

Thank you for this! 🙏🏽

[@zaranabeel166]

Thank you so much you, are literally saving my life I AM DESPERATELY BEGGING YOU I HAVE AN EXAM ON 15th PLEASE UPLOAD THE REST OF THE VIDEO :(( I can not count on anyone but you, PLEASE

[@alaeharkasse7974]

Hello, can I know why the concentration of drug 2 gonna be high in the blood and low in the tubule? 10:38

[@mugheerafaizan5940]

As you explained in the "secretion" that if a drug is non-polar, hydrophobic, small it will be easier to filter into the tubules, but these are the same qualities that are needed to reabsorb anything back into the blood, if anyone can explain it to me in replies I'll be very thankful.

[@rityomamaa]

Omg, finally someone with the same question. Have you found the answer yet? Because I don't get this either.

[@mugheerafaizan5940]

@@rityomamaa nope 😂

[@mugheerafaizan5940]

@@rityomamaa nope 😂

[@khanchaand8063]

So thats what he explained at the end that non polar can easily pass through paratubular cappillaries. So in order to inhibit non polar will have to be converted into polar. So changing the ph of urine we can convert these ions into polar that cannot pass through and trap inside urine. He also used lechatlier principle at the end❤❤❤

[@Sk1pperCS]

@@khanchaand8063 Thanks.

[@blukablazer]

Thank you very much , Good and efficient lecturing

[@aasemahsan]

15:39 Controlling overdose by preventing reabsorption ❤

[@zeynepp123u]

❤

[@raamishsiddiqui7330]

You are literally THE BEST 💗💗💗life saviour

[@sahalturky9169]

Thanks pro I'm from somaliland I learn more more.

[@resumezone]

Literally i don't have enough words to appreciate your efforts 🙏

[@clarinaackerman8639]

11:06 How could it possible that the concentration of the drug inside the bowman capsule are higher than the d.t.c.? Anyone please help me by explaining this

[@dinarmeltiara5456]

you did a very great explanation, cant thank enough 😭

[@ridabatool3525]

Sir Zach, really hats off to you. You literally deserve more than 1 million subscriber💚

[@Self-Health-Evangelist]

Thank you for your time and help

[@mishkalmujjalla8286]

Most respectfully sir Thanks for this videos free provide on you tube channel 👍

[@Val6035]

pharmacodynamics please!!! i have a test about it next wednesday!!!

[@nilkanthasharrma3455]

Iam watching this video from Nepal

[@rayanisam6089]

It was very hard for me to understand this part of general pharma , thanks for benign a master of this 💓

[@doctor9410]

man v will donate once we start earning ❤…praying for your health 😊

[@BaoTran-ls7oy]

Great explanation, thank you.

[@karmagaming7112]

Love u 3000 ❤️ We are Ninja Nerds 🥷

[@manalemad1589]

here comes the perfection ❤❤❤

[@SofiaNoor-y9z]

Perfect video thank you so so much

[@diogoferreira109]

omg beautifully explained

[@mustafa-M2j6]

great love for you from iraq ❤️‍🔥

[@uroojfatima8361]

Thankyouuuu so muchhhhh 🥹🫶🏽🫶🏽

[@albertobacci6265]

very very helpful, thank you!!

[@Medschoolsufferer]

@ninjanerds please do a video on Pharmacodynamics.

[@zeeshanasif3051]

Fantastic.please make videos on electrolyte disturbances.regards from pakistan.

[@dibyasattwakarmakar]

Thank You, Sir

[@niyadeo7970]

Amazing!!

[@wajahatabbasi5673]

iAM big fan of you sir thank u so much

[@taramyatt4563]

Do you have videos on pharmacokinetic dosing of antibiotics? Or have a recommendation on who to watch? Thank you

[@sameerishaque7635]

He made a video on dosage regimen.Can't find the link atm

[@PerfusionPrime]

Thank u ninja nerd

[@kellymca4]

6:55 is Secretion

[@juliamoretz1013]

You rock!! Thank you!!

[@shittuolamideayoola5687]

Thank you🎉

[@najiyounis9541]

Thank u from libya

[@omersardar6896]

thank you so much

[@vandhanachettiappillyhari5171]

Great explaination! Have you yet uploaded the next one about clearance and half life?

[@samiaridhi2668]

Can u make a video list where you are discussing about the tricks of solving u world

[@AmnaSaeed-o3g]

Please make video on autocoid

[@lordbishopkingmakercaraniu4118]

I never understood the acid base effects before you

[@hamzahajomar5614]

Thank you

[@christiandad5920]

Bro how long did it take you to remember all this knowledge??! You have photographic memory? You make it easy to follow but bugger me if I remember it like you explain it.

[@ranaumair4468]

please make a video on jak inhibitors

[@mimiluna8195]

I cant thank u enough

[@waseemakbar8435]

Almighty bless u ...

[@yashshah4140]

Influx Transporter dose not require ATP. Example:OAT,OCT,PEPT

[@prayashasharma1962]

Why the small hydrophilic drug conc is less in lumen ?

[@2weeksago642]

How do I contact Ninja Nerd? I have a question regarding an illness that my brother has.

[@2guptanshu]

Thanks

[@bernadimalik8635]

Are you sure that polar and nonpolar drugs are not confused with their molecular weight ? What I know is Polar drugs using Glomerular Filtration Rate have small molecule. **Im confused.

[@lokeshhr8596]

bro can u plz do a vdo on pharmacokinetics introduction..

[@brucedressel8873]

Pharmacy the root word is the Greek word Pharmakeia which comes from the Hebrew word Kashaph which is Sorcery.

[@abcdefgh-lx3kz]

wow, that is atttractive man

[@lydiakaoudjt9369]

The best

[@RidaBatool-id3fv]

From where we can get this Lecture notes

[@Syedhussein89]

Zach pls explain this …if a drug is coming from liver which has undergone phase 1 & phase 2 rxns…it becomes polar .. as u said …then how in kidneys the non polar drug molecules can be excreted out . ? It’s v confusing

[@Npg153]

For excretion of drugs by glomerular filtration, the main determinant is plasma protein binding , the drug bound to plasma protein can't be filtered, all other form of drug can be filtered.

[@samisp4672]

Do you have any video on pcos ?

[@tasneemalhasan5317]

I LOVE YOU

[@amirabbasbaharfar2328]

Done.✅

[@user-nq4mw3cu4t]

الصوره 7:44

[@hamzahajomar5614]

All of this is in our body's and there's people think that Allah is not exists

[@noorkhaled1585]

سبحان الله 👏

[@fatimaahmed7909]

It's true he doesn't exist

[@wandererrrrrr]

سبحانك اللهم❤

[@helabarby3922]

Alhamdulila❤❤

[@barbarvssa]

Idk if it's sarcastic but couldn't you keep a belief seperated from a fact for an hour? Everything has a time and place.

[@michealraptor8424]

good sir where do you get your uestion from

[@bennydevinobenito2993]

Virtual Reality (VR) is a computer-generated environment with scenes and objects that appear to be real, making the user feel they are immersed in their surroundings. This environment is perceived through a device known as a Virtual Reality headset or helmet. Mixed reality (MR) is a user environment in which physical reality and digital content are combined in a way that enables interaction with and among real-world and virtual objects. Augmented reality is an interactive experience of a real-world environment where the objects that reside in the real world are enhanced by computer-generated perceptual information, sometimes across multiple sensory modalities, including visual, auditory, haptic, somatosensory and olfactory. Wikipedia

[@brucedressel8873]

I have had 3 crainiotomies over the past 2.5 years. My body hates allopathic drugs the worst of which was dexamethasone what a crazy steroid this weirdness is.

[@mustafaadnan6120]

We want histology lectures….please

[@sahalturky9169]

We need

[@mustafaadnan6120]

@@sahalturky9169 sorry😚

[@matthewpalumbo9357]

Dang you are smart

[@missh6773]

I want to talk to you very important directly how could i do that please

[@EmmanuelMwaifunga]

How can I be more than this in school of medicine

[@sumaiyaislam9377]

💙💙💙💙💙

[@mayraconcepcion6815]

Marker drops.... Son of a Gun 😆🤣

[@BadBad-i7m]

لا إله إلا الله وحده لا شريك له

[@aayushbatra1147]

❤❤❤❤❤❤