Objective Evidence for PSSD | An Interview with Dr. Irwin Goldstein

[@johnnyecoman9121]

As soon as the paper is published a press release urgently to be sent to the media. The press will pick it up straight away.

[@snowps1]

It will not be reported in the media because all media is sponsored by Pfizer

[@matty96465]

Post Finasteride Syndrome & Post SSRI patients everywhere cannot thank you both enough for this content.

[@frankyfourfingers1382]

Absolutely horrifying and disgusting.

[@neo-climb5627]

Thank you Josef and Irwin. After 10 years of PSSD I've lost my faith in doctors, in the government, in humanity. Your work and attitude helps to restore a small amount of that faith, even though it is impossible to access any proper care where I live. The gaslighting is beginning to stop though. It's impossible to deny pssd exists any longer without looking like a fool or someone with their own agenda.

[@luisabremke5344]

Thanks so much for talking about PSSD. I am a PSSD sufferer myself. I can't put into words how severe this condition is and how it changed every aspect of my life as I suffer from severe emotional blunting next to 100% sexual dysfunction. I am 27 years old and I don't know how to live a decent life with this condition. For me it doesn't seem possible, no matter how hard I try. This iatrogenic harm is dehumanizing. My last hope is that there will be some form of treatment in the near future. Thanks for bringing some evidence into this condition while sufferers often get gaslighted. All the best, Malu

[@TheDavveponken]

Hold on to hope and stick it out, it does get better. I am no where near recovered but I saw a definite shift after six months, getting back some erection and after another six months some more. At 15 months I am starting to feel a little more like normal. I have windows of normality, so I have to say I am beginning to see the light. Even if it also shines light on all that is bad as well. Stick it out and hopefully you/we will recover. I read a few recoveries over at the pssd subreddit, it took them about 2-3 years. All the best, to anyone reading this, you are not alone.

[@natanfarias7814]

​@@TheDavveponkenHello, could you send me the link to this subreddit?

[@natanfarias7814]

​@@TheDavveponkenI also have faith that we will all recover, hopefully they find a cure soon 🙏🏼🥺

[@wordsleuth992]

How do woman experience PSSD? Does it affect their tissue in a similar way??

[@TheDavveponken]

@@wordsleuth992 numbness and desensitization

[@UniqueYoutubeHandle13]

Commenting for the algorithm.

[@The_New_Abnormal_World_Order]

This is criminal.

[@hulk-jv6cz]

Ssris should be totally banned.

[@Hassan3hunna]

Same for Antipsychotics I got PSSD from Antipsychotic prescribed for Schizophrenia

[@Slidehhy]

​@@Hassan3hunnahow long ago?

[@Hassan3hunna]

@@Slidehhy 11 years ago

[@Slidehhy]

@@Hassan3hunna wow

[@MultiMcgurk]

@@Hassan3hunnadoubt it Probaly Just body healing

[@1summerflower]

I was on meds for 8 years low does didn’t always take them everyday , I was just stopped on them went through withdraw without knowing it , I almost didn’t survive went into full menopause, felt so bad , I was able to get a mri , they tried to make it out like I was crazy until it came back as a pituitary tumor. I continue to suffer and can’t find a doctor. All the awful things I’ve experienced and continue to is blame on menopause, it’s not though . Since I stopped my meds it has been the worst time in my life. I almost didn’t survive. Everytime I have a health problem I find more accurate information then doctors could ever have. Going to the doctor makes me physically sick. Most the time it’s hard to even find words for all this let alone wrap my mind around how healthcare has been abusing people.

[@KathleenMottinger]

I'm so sorry. You will get well again. I'm 83 and dealing with psyche med injury and also without any doctor. But they are useless anyway. GOD BLESS.

[@nicolelambic]

when you say menopause, do you mean that you stopped menstruating? Or do you mean that in your blood tests you are showing menopausal (elevated FSH)? How old are you?

[@luisabremke5344]

It's time that every medical expert watch this video! It could prevent so much suffering of young innocent young people. Informed consent is long overdue.

[@DJTechnoboom]

everyday is a living nightmare now

[@TheDavveponken]

[@Slidehhy]

EVERYDAY

[@afkVahn]

Doctors, I hope you appreciate the severity of what PSSD, much like PFS from finasteride, is. Seeing your genital tissues destroyed and your sexuality shot to pieces, probably for life, is a true never-ending nightmare. If it turns out this is actually irreversible, I will give up on this life. With respect, but these syndromes are in a completely different ballpark than withdrawal. It needs to be recognized as such. Thank you both for raising awareness!

[@TheDavveponken]

I had a brief read on the finasteride recovery forum and seemingly the tissue repairs itself as the body gets rid of the drug and heals. It seems to take a few years before that happens though. Personally it's been 14 months and it really has been getting A LOT better the past month or so. I think 5mg cialis daily in combination with l-arginine and l-citrulline and making sure you have the vitamins you need, such as vitamin d, vitamin c, vitamin k2, vitamin e, magnesium, zink, omega-3 etc. All in order to heal your vascular system and your smooth muscle in your genitals (they are the same). That and exercise. I hope we will all recover. It took me a year to get windows of my past self cognitively. The reddit pssd forum seems like a good resource in the meantime (I looked at it the other day).

[@mcb00]

With respect, I personally found withdrawal caused me a lot more suffering than sexual dysfunction. Also, the avolition and chronic fatigue parts of PSSD caused me more disability and trauma than the sexual dysfunction. I feel I can live without great sex, but without energy, motivation, interest, passion, it's like you lose your soul.

[@TheDavveponken]

@@mcb00 I second this. I felt, and still feel to a large extent that I died during that week last summer. Not being able to think, feel and experience the world (including sex) is what has me considering suicide (the moments are briefer now, but still persist each and every day). It is also crippling financially and socially. It's very disabling and soul crushing (to not even be able to enjoy music or the wind at your face). It's like I can still feel what it did to my body and mind - it changed it and I'm no longer me. Very alien.

[@mcb00]

@@TheDavveponken I understand. I have been able to recover some of it back with intensive rehabilitation (behavioral activation and other forms of emotional therapy). Therapy works, not because this is "in our minds", but because it can use neuroplasticity to rewire the brain reward pathways. We're not gone. We're buried under all this, and can find ourselves again with a lot of time and work. I'm sorry you find yourself in this traumatic situation. I hope you find a way to find yourself again too. There is hope ❤️

[@TheDavveponken]

@@mcb00 Thank you for the kind words. Wishing you further recovery as well

[@pjjmsn]

The doctor mentioned that SSRIs can help with suicide, but it should be pointed out that they also increase the risk for suicide in many people. I seem to recall that Josef did a podcast on that.

[@mcb00]

They do, both by increasing anxiety and mania as a side effects in some people, and by causing agitation/akathisia in cases of severe withdrawal.

[@TheDavveponken]

They can also increase the risk of actual suicide if the effect is emotional blunting. If you've considered it a long time you might go through with it if you are no longer scared of it or sad about it. The gray new reality stript of pleasure can also be the last straw.

[@mcb00]

@@TheDavveponken it's possible, although I have to say, for me, I still know what is right even if I don't feel it strongly. I know my death would cause pain and trauma to the people I love, and no amount of blunting takes that knowledge away.

[@TheDavveponken]

@@mcb00 Yeah, I know what you mean. But it's not a matter of right or wrong at a certain point. It is your life, you're the one having to live it and if you can't think or experience pleasure anymore it is very tough to think you will have to live through that for another 50 years. For me, luckily remembering how things used to be and having hope, and a lot of rage (when it finally came back), kept me alive long enough to see improvement. Also I think I stayed alive for my sister and a few friends, as well for my "inner child", he deserves a fighting chance still. Now I have more hope. But I have a newfound appreciation for why people kill themselves on or after antidepressants etc. I had heard of antidepressants being bad but I didn't know it would be true for most if not all psych drugs. I feel stupid for thinking otherwise. But no matter how strong or smart you are, trust is a powerful thing - and terrible if put in the wrong people.

[@mcb00]

@@TheDavveponken it depends on so many things if psych meds are bad. Genetics, dose, duration of use. I personally think in some very limited circumstances they are needed, especially for short term crises. There needs to be a LOT more thought put into the balance of risks and benefits though. And it needs to be a very individual decision, instead of going by the label, it has to be based on the person and their circumstances: personality, life history, drug history, support available, genetics, accesss to safer treatment, current coping skills, etc.

[@jboesky8]

Thank you, Josef and Dr. Goldstein! This video is so alarming. It’s also incredibly informative… Josef, please consider asking Dr. Goldstein to come back on one day soon to talk about PFS ( post Finasteride Syndrome.) I know that Dr. Goldstein has also tried to help countless PFS sufferers as well. Thank you, Josef! John B. 🙌

[@loubeauchamp9680]

Also all of the other drugs that can cause PSSD please. Adequate informed consent is not happening.

[@JazzmatazzSSM]

Thanks, Dr Joseph! You're becoming one of our strongest allies in raising awareness of our problem. I hope we'll all recover that part of our lives that was taken from us and people get fair compensation. This is textbook uninformed consent.

[@TheDavveponken]

Is that grounds for legal action you meab?

[@brock_logic]

You lost more than a part of your life you lost a fair amount of quantity of life for your whole life

[@spoonbillyerd]

pssd takes away your brain

[@tmtb80]

The psych dept should be ashamed that the Urologists spend more time (3 hours!)diagnosing the poor patient who was given the ssri how quickly? They say the average time it takes to get a psych diagnosis from a psychiatrist is 7 minutes.

[@crazycreed6675]

Please get in contact with Vice News you have alot of popularity to have that Access

[@anteg9084]

And possibly Lisa Ling! (Of the "This Is Life" series.)

[@christopherp.8868]

Another great interview. Looking forward to more😊

[@minkworks6143]

Love you doctor WD. Thank you for everything you do to raise awareness about PSSD.

[@alexanderp8037]

I've also seen people getting "PSSD" or permanent sexual dysfunction from antipsychotics too. Personally i think it got to do with TRP channels and sodium channels

[@TheDavveponken]

would you mind elaborating? I'm currently suffering.

[@alexanderp8037]

@@TheDavveponken the neuropsychiatrist who treated me a long time ago told me sensitivity of the penis is controlled by TRP channels which control sensation of heat, cold, shocks, osmotic pressure and vibration. The wikipedia page is pretty good look up "transient receptor potential channels" its a whole family of receptors appearantly SSRI can influence these receptors. You can also find studies by marcel waldinger who investigated this and tried experimental treatments

[@Hassan3hunna]

I got it from Antipsychotic so I can second this

[@bobbyziggy85]

check your serum prolactin, antipsychotics can cause elevated prolactin levels

[@shutoffsoul]

PSSD has destroyed all aspects of my life and will be the cause of my death

[@TheDavveponken]

Hope it won't be so. I feel you, I have the same thoughts every day. I keep on hoping though. I read some recovery cases on reddit after about 2 years.

[@shutoffsoul]

@@TheDavveponken its been 3 years.. Also did you even watch the video? Its tissue damage, no wonder people have had pssd for decades I don't believe in recovery

[@mcb00]

Please don't. Some people are getting better even after years. There are different ways to express sexuality and you can explore ways to work around it too. Talk to a sex therapist. I wish you well.

[@Snowflake1374]

Same.

[@bethanydavis5120]

Thank you for creating this content and raising awareness!!!

[@adrianenglish511]

Commenting to raise awareness about this toxic medicine

[@wakinyjantabart8622]

IF SSRIs can cause permanent penile tissue damage in young men (and affect women’s genitals as well) they should definitely be banned! How could their use be justified. AS a GP I want to see studies like measurements of penile nocturnal erections in people with PSSD symptoms and matched on age and health status controls.

[@JetPackFlame]

Such studies already exist for PFS patients, thanks to Dr Goldstein, but the medical establishment continues to ignore them. I suspect they will respond in the same way for similar research pertaining to PSSD patients.

[@singstreetcar5881]

Why do psychiatrists hate consent?

[@loubeauchamp9680]

'cos nobody would take the "medicines"

[@mcb00]

Because people with emotional issues are treated by society, not just psychiatrists, as children. Decisions are made for them because the stigma is that they lack the judgement to make decisions about their emotions by themselves.

[@Kalks95]

Amazing content as usual, thank you both.

[@MistyRane]

Heart wrenching. Thanks for getting the word out

[@TheDavveponken]

Thank you for this Josef!

[@kilianred9890]

Sexual issues is one thing, but anhedonia and emotional blunting is another. They are all linked too and makes it harder to solve. What's the point improving erection if you can't feel pleasure and don't even want to play with someone...

[@Snowflake1374]

Off zoloft 13 year use. Pssd, ahedonia numb feelings. Dysfunctional, ruined my life.

[@Piocoto123]

As a medicinal chemist, I dream of finding new psychoactive pharmaceuticals that don't have this kind of effects... I mean there exist some substances with amazing antidepressive potential llike ketamine and even psychedelics (come with other important risks) but neither of them must be taken daily nor for years on end... But that is something pharma could not profit a lot

[@nishantpatil1799]

There should be a ban on SSRIs.Doctors from hell keep overprescribing these drugs from hell

[@donquihote6023]

The Title Doctor has become a Four letter word.

[@JC-xx5dm]

Really persuasive video. Will be interesting to see how quickly things start moving as more specialists begin to share what they are seeing.

[@mirenhary1566]

Thank you

[@alexanderp8037]

I never suffered from PSSD but it do have reduced sensitivity and orgasms persisting after stopping antipsychotics

[@millymiu]

That is also considered pssd. Just a mild case.

[@Hassan3hunna]

Antipsychotic can cause PSSD as well I got it from Antipsychotic prescribed for Schizophrenia

[@MultiMcgurk]

@@Hassan3hunnadoubt it

[@Hassan3hunna]

@@MultiMcgurk I have been suffering from it since 10 years now

[@MultiMcgurk]

@@Hassan3hunna numbness ?

[@TheDavveponken]

Inspired by this and the previous video here on pssd emphasing tidsue damage I fid some research and am now wondering if we aren't suffering from the autoimmune disease systemic sclerosis? It can be triggered by various medication or other stressors. Any thoughts?

[@vanmajk1940]

Great work

[@lo9761]

So awful I’m 16 and I trusted my parents and physciatrists and it ruined my life my parents didn’t even research about this noeone told me anything would happen and it’s all in my ehH

[@Melsincatuation]

Hi doc..I hope u got my other comment.. Just a reminder.. PLEASE do a video on the illness PANDAS!!.

[@adamscaife6931]

Is there a way to get this genital tissue damage checked?

[@TheDavveponken]

he said ultrasound?

[@recynd77]

I wonder if post-SSRI disorder helps account for the rise in ADHD disorders/stimulant prescriptions?

[@TheDavveponken]

How do you mean? That they are getting adhd diagnosis due to pssd? I was lied to and took Ritalin for a bs adhd diagnosis and got pssd as well. Ritalin isn't unlike ssri as it does the same exact thing (I found a study on elevated serotonin in rats several months after ritalin).

[@recynd77]

@@TheDavveponken First: you have my utmost sympathy; I, too, was physically harmed by psychiatric drugs; I am especially appalled by the current trend of prescribing SSRIs to pregnant women. I wasn’t thinking of ADHD mis-diagnoses as much as I was SSRI-induced brain damage that presents as ADHD. I’d be interested in looking at your evidence that stimulants and SSRIs are “exactly the same” [paraphrased]; stimulants, AFAIK, target dopamine and norepinephrine instead of inhibiting serotonin reuptake. (I do have ADHD; I spent nearly three decades mis-diagnosed and -treated, to no avail. Once I was finally dx’d and treated correctly for ADHD, my life became-and stayed objectively better.) I have taken both types of drugs, and I have had MUCH better results with stimulants, though I’d never say they’re without consequences…and I would be loathe to give either stimulants or SSRIs to my child except under the most dire of circumstances. I also wonder if SSRIs (stimulants, too, maybe) play a role in the skyrocketing cases of autism…or the plummeting birth rates in Western countries. Any thoughts about this?

[@mcb00]

It's possible because stimulants can increase libido. Howver, low libido is not a symptom of ADD. What I think is happening a lot is that SSRIs cause a different type of depression where the person is more fatigued, has brain fog, lacks motivation, and that gets labeled ADD. Or it gets misdiagnosed as depression instead of an adverse reaction, and stimulants are added to the antidepressants to help with energy, cognition and/ot motivation. The issue is this doesn't work long term because stimulants cause tolerance and the SSRI is still causing damage while taken. Also, stimulants can result in a worsening of all these symptoms in some people even once off the drug.

[@recynd77]

@@mcb00 Appreciate this!

[@TheDavveponken]

@@mcb00 Agreed. There'd be a whole other level of negligence if a psychiatrist would diagnose adhd after they were fatigued/scattered from antidepressants. But it wouldn't surprise me. It still boggles me that they diagnose people with it before treating the "depression", but then again, by treating it, they will use drugs. And if my hypothesis is correct, people who are already at the brink of really poor health are the ones that are severely depressed. A friend of mine had been feeling off and low for years and was ofc suggested antidepressants, but she pressed on and got confirmation of thyroid disease. It seems that people who are only moderately depressed do fairly well with antidepressants (from what I've seen in my social circle), but then people like me who were in worse health and more "depressed" (I do hate this word after all that's happened, depression isn't real in the sense of an illness, you are just very sad and hopeless - nothing wrong with your brain really - no chemical imbalance etc) react badly because we are in poorer shape. I for one had raised liver values, alat and asat, but my idiot doctor didn't think any of this. Apparently methylphenidate is metablized in the liver and in rare cases can cause liver damage; but chiefly, if a liver that is impaired is all of a sudden given the enormous task of metablizing ritalin the risk of accumulating ritalin is high. A neurologist confirmed the likelihood of slow metabolism being the culptrit. I also took acid reflux medication (dampening acid). I think I accumulated pretty much all of what I took those 8 days.

[@tmtb80]

How infuriating.

[@lesleysears9808]

Love 💕 that you came up with this word!!🎉

[@rogernelson1870]

Pssd has ruined my life my marriage and I don’t want to live anymore

[@Slidehhy]

Same how long are u like this

[@cervantes3879]

Perfect video...

[@christofferbrandel6491]

I don't have ED but genital anesthesia, I'd really want a scan but don't live close to the US.

[@estelled389]

Omg HENIOUS CRIME

[@Hassan3hunna]

Can PRP injection shot or Shock wave therapy heal the penis tissue damage?

[@rxcoco12]

Any studies on tissue in women?

[@ancabostinariu6550]

Educational.

[@TheDavveponken]

Could it partly be vasospasm?

[@namejantechao3207]

ssri's fcuked my life forever

[@ikramellah]

33 years old , taking paxil for 2 years! , years after stopping can't get a normal erection 😢 ,genital hypoesthesia ,

[@Uma921]

30:29 amphetamine salt… like, aderral?

[@TheDavveponken]

ritalin caused me pssd

[@mcb00]

Most stimulants are amphetamine derivatives. There are some exceptions like Strattera (sp?) or Provigil (this is a waking agent that has stimulant properties). Most commonly used stimulants (Ritalin, Adderall) are amphetamines in the same chemical family as metamphetamine.

[@MultiMcgurk]

@@TheDavveponkenimpossible

[@TheDavveponken]

@@MultiMcgurk go away

[@MultiMcgurk]

@@TheDavveponken only been honest mate