OCT Retinal Ganglion Cell Analysis

[@aapt9887]

I had a young patient who had had multiple MS related retrobulbar neuritis episodes but only the most recent one caused vision to get so bad she seeked an ophthalmologist. Looking at her OCT RNFL it was almost normal except a slight thinning of the temporal RNFL. Ganglion cell analysis however showed a markedly thinned ganglion cell layer in both eyes - apparently a hallmark of multiple MS related episodes. Brain MRI confirmed MS type lesions.

[@HippocratesofCos]

I'd go even further than this in describing the advantages of MGCL analysis. MGCL change happens faster than RNFL change, and is less affected by normal anatomical variations. The MGCL is superior to RNFL in detecting pre-perimetric compressive neuropathies. It will often be very abnormal in patients who have had neuritus, even if VA, 24-2 & Ishihara have normalised. And likewise it can detect nutritional neuropathies in patients whose RNFL and VA are still normal.

[@9791Mars]

Thank you so much ❤

[@84BMA]

Thank you

[@camiloromero9893]

Hi Dr Lee, I saw a patient with a SCA and ophtalmologic compromise, tell us your approach to SCA from a Neuro-op perspective.....thanks Camilo