p53: Introduction to the p53 tumor suppressor protein and its function

This is the first in a series of videos on the p53 tumor suppressor protein, known as the “Guardian of the Genome.” It introduces the biological function of p53 as well as addresses it’s regulation by the mdm2 ubiquitin ligase.

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Thanks for the video, but why some people with p53 mutation get cancers while others with the same mutation do not?