Pharmacology - ALPHA & BETA BLOCKERS - ADRENERGIC ANTAGONISTS ( MADE EASY)

[@SpeedPharmacology]

🚀 Elevate Your Pharm Game! 📚 Join Patreon for A+ Study Notes! 👉 www.patreon.com/speedpharmacology 👈

[@DavidLodgeclassof]

My takeaway: if you're an alpha, you osin ("is in") the in group, but if you're beta, then lol.

[@Bitter_Biscuit]

thanks that a good way to memorize

[@nationalhamleague5352]

Finally incel logic came of some use XD

[@MrSandChess]

This just changed my life, thank you.

[@asadtyagi6026]

Thank you

[@desireet3644]

Lmao thank you

[@ahmadalthabteh9587]

Guys, here is a way to remember which drugs belong to what group between the 1st generation and 2nd generation drugs of the BETA Blockers. (Note: this method only works for the drugs mentioned in this video). So just remember the letter M, which is the letter that comes in the middle of the alphabet (there are 26 letters in the alphabet, it is the 13th letter). So any drug that starts with any letter from A through M (so any drug that begins with a letter in the first half of the alphabet) belongs in B1 selective antagonists and any letter that starts from N through Z (so any letter that starts with a letter in the second half of the alphabet) belongs in non-selective (1st generation) BETA blockers. Hope this helps...

[@melissamanzanares8225]

Huedini protocol

[@RM23459]

Wow.....you saved my life. Thanks

[@jannmikoingelrabagogamingc6012]

Hey! Just wanna say "Thanks!" for this helpful tip, really. 😊

[@Domiimami]

Thank you for the tip!

[@edennishan717]

Thankyouuu 😭🫶

[@mccallipz]

Just discovered this channel while studying for my pharmacology exam tomorrow, and I saw this video was uploaded just yesterday! Thanks for coming in clutch, and keep up the great content!

[@Hs-mh1km]

7 years later now I'm studying for my pharma exam tomorrow.

[@kingsleyacquah3756]

Samee😭

[@Ahmedali-do2ng]

for the first time in my life I finished a Pharma topic without falling asleep :) thank u so much and keep going

[@m.hussain3384]

Hahahaha exactly

[@carringtonbearden4479]

These videos are amazing! If I had found them earlier in the semester I might have done better on my first Pharm exam! These videos break down 3 hours of lecture into something I can truly understand and you can bet I am using these videos for the rest of my nursing classes. Thank you so much! You are a Godsend and please keep it up!

[@banadaaboul4792]

I have been reading for two hours about alpha blockers but there were many things I didn't understand. In here only five minutes but It did answer all my questions. Amazing ,Thanks 😄

[@ammarmemon8925]

Yeah me too😁😁

[@thepharmacistacademy]

I remember watching this video back in pharmacy school when it was first uploaded. Really helped me thanks

[@dayanawiggins6457]

I really want to thank you. You have rescue my brain and I can now understand the pharmacodynamics of the ANS drugs :)

[@zinaalabdaly6848]

You are a savior, i have an exam tomorrow and this was quick and simple to understand Thanks !

[@labs2798]

Words can not explain how easy you have made such a lengthy topic! Hooked to your pharma videos

[@tearlesereph]

this is crazy good and useful! I finally understand what all these alpha and beta things are in my pharm class. Thank you so so much!! Your video is simple, straight to the point and easy to follow and understand compared to all the other ones out there.

[@dinobutt]

Thanks for this channel. I'm currently working on my pre-reqs to apply to pharmacy school. However, I wan't to try to learn as much pharmacology as I can to truly be prepared when I get accepted. Keep the videos coming, you have a new subscriber.

[@ryanmartin3012]

Did you start your pharm school studies? ☺️

[@telesiagerstle2908]

I already subscribe coz I’m in my mid to late 60s w HBP for the past 15 plus yrs, it’s so easy to understand & learn what alpha & beta blockers are & how they function in treating HBP & for those w heart prob, something doctors don’t do or explain b4 they write a prescription, how can a patient know & understand what & how this med that was just prescribe, I guess all we have to do is get & take, which is & have been the norm unless we ask questions, so these videos are so informative & teach us what they’re suppose to do, ThankU so much for ur kindness & good hearted work the time & effort, may God bless you & yours, w good health & happiness, especially in 2018 & beyond, keep up the good work, ThankU & Happy 2018!!

[@hallahachemi1871]

it is not as easy to explain in few minutes during your visit/checkup. it is even hard for us student to understand so imagine a patient who doesnt know many of this stuff that were explained in 3 videos if almost 10min each. i appreciate your curiosity in learning how things works, but i dont think many people are willing to do the same

[@HostileUterus]

Thank you thank you thank you! I have a patho/pharmacotherapy test next week and I learned more from you than my teacher!

[@xinnansong892]

The alpha 2 receptor agonist dexmedetomidine is widely used in clinical practice, especially in anesthesiology and critical care medicine.

[@paperworks8777]

whoa! I can understand this. My professor seems to be talking in another language when discussing these but you've made it simple and easy to understand. Thank you very much and keep making great videos!

[@PranaYanna]

This was so helpful for my nursing pharm final thank you!

[@devintriantos]

You are a godsend. Paramedic student. Thank you sir. I find your explanations helpful.

[@stellaroberts6913]

Today i have been asked about these blockers and i didn't know them 😭 so i am watching these now, if you don't know a thing it doesn't mean that you're unsuccessful, it just mean you need more information

[@basicmed7514]

I’m using these videos as an introduction and then I’ll use sketchy pharm and anki to reinforce them

[@abdurahmanhassan2325]

😂💯

[@kishalpatel]

Thank you for the video, it was kind of refreshing pharmacology after long period of graduation.

[@isururajaguru4418]

You are really a savior for us... thankyou for making things much simple and easier to understand🙏🏼🙏🏼

[@jacquelinemichael2201]

very clear explanations, thanks a lot for your videos.

[@miko6141]

im really grateful for your existence

[@issacgeorgy8289]

The best video series about ANS!!

[@abbhardwaj9019]

My Pharmacology exam is tomorrow and I'm here at the last minute. Very helpful video, helpful enough that I'm actually leaving a comment which I rarely do. Haha

[@carolTroy-tt6xe]

Ohhmy you just saved my semester ❤

[@alemhamdard6612]

Very good and fruitful short lecture! If we read the Lippincott Pharmacology book along with these lectures, it will be very high efficient for us.

[@jeanjvr3894]

Thank u sir! This is very helpful. I am currently preparing for the PLE this Nov (hopefully 🙏) and pharma is literally giving me headaches because of too much drugs. Your videos is short but too much info. It easily helps me understand and appreciate pharma. 👍🏼

[@robyn9080]

Wow thanks for this video, good summary with pictures!! Had to subscribe, I needed this since I have an exam and this puts it all together. Thanks again.

[@lydiatazdait7593]

Thank you sooo much , it was clear , it was well explained and the pictures you put really helped keeping all the informations in mind thank you again

[@noobiewatcherz9938]

Edit Dec 24, 2018 .. Edit these later. 1:25 Phentolamine, phenoxybenzamine for hypertension caused by Pheochromocytoma (tumor that secretes norepinephrine, epinephrine. Acts on A2 receptors to inhibit its own release so blockade of these receptors result in more no-rep release. Norep stimulates --> B1 receptors on heart ... that's why non-select P,P can cause Tachycardia and cardiac arrhythmia. Phenoxybenzamine is an irreversible antagonist and only way body can overcome it is if body makes new adrenergic receptors which takes about 24 h. Phentolamine is reversible antagonist (lasts 4h 2:50 Selective block A1 receptors located mainly in vascular smooth muscle which reduces peripheral resistance and leads to decreased BP and also relaxes smooth muscles in the bladder neck --> USED for BPH (enlarged Prostate) 3:28 Think "zoesin" 3:40 Prazosin PDT Doxazosin hypertentsioin ( little effect on BPH Terrazosin Tamsulosin Alfuzosin BPH (little effect on BP) because these targets A1 in prostate Silodosin 4:30 Vasodilation 5:18 A & B are both has selective and non-selective 5:30 Beta blockers are competitive inhibitors at beta adrenergic receptors and they counter effects of catecholamines (Epinephrine, Nor Ep) ( which is why this is useful in treatment of hypertension, HF, H attack, angina, cardiac arrhthmias, also treatment of glaucoma and migraine prophylaxis 6:20 1st gen PIC. Propranolol, Pindolol, Nadolol, Sotalol, Timolol. acts on B1 receptors on heart --> HR down , delayed conduction through AV node and Contractility down so the final outcome is less Cardiac otuput and decreased oxygen demand on the heart muscle 6:49 Propranolol can penetrate to CNS ,, can be used for migraine prophylaxis 7:00 Timolol eye = reduces intraocular pressure 7:17 B2 receptors in lungs (*these being blocked --> bronnchoconstriction (DON'T if COPD, asthma 7:38 B blocker 2nd generation (targets B1 receptors) / cardioselective beta blockers BEAMS atenolol , acebutolol , Bisoprolol , Esmolol , Metoprolol 8:20 3rd generation has selective and nonselective B blockers. Unlike gen 1 or 2 , these 3rd generation= act on blood vessels . Non selective (B + A1 ) Carvedilol, Labetalol . B1 selective = nebivolol vasodilation by releasising Nitric Oxide from endotehelial cells. Betaxolol v .. by additionally blocking Calcium channels ( CCB) .. also can be applied to eye ,glaucoma, . 9:50 Carvedilol and nebivolol have natioxidant properties (preferred for HF also alongside commonly prescribed with Bisoprolol and Metoprolol 10:07 Intrinsic sympathomimetic properties (Pindolol, Acebutolol . Pindolol and Acebutolol not only block but also to weakly stimulate both Beta 1+2 receptors which leads to diminished effect on cardiac rate and output. These 2 are for pt who can't tolerate other Beta blockers because of pre existing bradycardia or heart block .

[@KawishAnserDM]

What is the difference in selective and non selective alpha blokers

[@mourilshah2054]

Selective alpha blocker only blocks alpha 1 receptor while non selective alpha blockers blocks alpha 1 as well as alpha 2

[@DrPrashemMajumdar]

Short and effective, as always

[@Ahmed-vk6if]

شرح مثالي و مفصل و مرتب شكراً جداً 👏👏😍😍

[@clarityashes344]

I so appreciate you making these videos. Helps me study for my HESI exam!

[@lynnecota9103]

This was a great video. Subscribed to your channel. I appreciate the time you put into making it. Thank you!

[@jackadams781]

Thank you Dr. Doofenshmirtz

[@muhammadmohib7927]

😂😂

[@Chinmayi-S]

This is really helpful. Thanks a lot Sir. Helps me keep up in Pharmacology even at the last moment.

[@danivinan2922]

Gracias por los subtítulos en español 😊. ¡Muy buenos vídeos!

[@SpeedPharmacology]

De nada :)

[@maham9777]

Thanks ,you really made it easy . The best channel for pharmacology 👏🏻👏🏻👏🏻

[@apoorvtyagi7441]

Here are some mnemonics - Esmolol can be remermbered by two Es as it starts with an E E - Early action means rapid or fast action so it is used for pre and intra operative hypertension E - Erythrocytes. It is metabolised in erythrocytes so it does not undergo metabolism in liver or kidneys Phenoxybenzamine has b in it which means before so it is given for pre-op HTN in pheochromocytoma Phentolamine has l in it so it given later means it is given for intra-op HTN in pheochormocytoma “Scorpions Prey and Pee” Scorpions - scorpion bite Prey - prazosin Pee - PE means pulmonary edema So Prazosin is a DOC for scorpion bite and Pulmonary edema

[@salaams14]

Your videos are great! very clear explanations, good speaking tone, and easy-to-follow flow charts! Thank you

[@rathnakumari2231]

Tysm fr the video...... It is very useful n easy to learn as well........ After watching this video once if v go through the text book it becomes easy to understand... Tysm 😍

[@rooory15]

Thank you so much tomorrow I have finally exams and you helped me 🙁❤️❤️

[@asfiyafakiha]

Loving your channel! Thank you! ✨🤍

[@sadiqarezaie2525]

Just one word THANK YOU SO MUCH SIR💚

[@daviddivineful]

Great explanation. Helped me in my pharma class. Appreciate the sharing and simplification of information.

[@aminalolol3063]

thank you so much. it was reeeeally useful and easy to understand. appreciate a lot!

[@mulengatito6978]

Let's take this guy to 1million subscribers

[@mohammedabd6696]

Every thing i need thanks a lot

[@drsheikh]

Excellent video, very sharp presentation. Thank you. Go on 👍

[@hfeencore6743]

You are hero my doctor explain this in 2.5 hours and didn’t understand well you in 10 min

[@shanzay149]

Awesome sir. U explained the basic concept. Thank u

[@Sonjabessy]

I love your videos! Very helpful! Would be great if you could write somewhere if there are new informations. For example if there is meanwhile an useful selective b2-blocker or not

[@sidrahtulmuntiha6148]

Best vedio so far 👍

[@AliKhalied-ek9uk]

I enjoyed the lecture, brief and sufficient thanks you.

[@yasmineyoussef2641]

Excellent presentation. Thank you!

[@daniash4457]

I really appreciated your videos and waiting for more, thank you a lot.

[@UHFStation1]

I am on the lowest level beta blocker every other day for arrhythmia. Still makes my feet cold, but my hands don't cramp up anymore. Scary drugs. I hope research on NAD+ precursors advances fast. I read muscles tend to work much better when cell metabolism is enhanced.

[@matchmedicines8209]

same as always, fantastic

[@anuj9749]

Play at 1.5x it's the best

[@adilhanin4444]

The best explanation ever.

[@arpanpramanik6784]

thank you speed pharmacology very much

[@sakshibisht6580]

Please make videos on CNS pharmacology, it will be really helpful ❤️

[@megcvar4446]

THANK YOU!!! I loved this video, its simple, clear to understand and I love the graphics that go with it. Will be watching your other videos. :)

[@muhammednauzad6903]

it is short but it is very very useful and effective

[@sarah36475]

wonderful explanation. i hope u make antibiotics videos

[@raddo6161]

This is very clear. Thank you very much

[@sumairanaz1949]

thank you so very much. Now I can see why I have different response to carvidilol and nebivolol

[@genevatabe5861]

Fantastic video. Thanks

[@shoroukragab8435]

Really useful channel thank you , we hope you do more videos i wish i could have these videos during my medical school time

[@nousheenrashid8470]

very very good, it's very precise and very accurate, like your way teaching.

[@ryanbadawi1442]

Brilliant 👏👏👏👏👏❤❤❤❤ Thank you so much ..you helped me a lot ❤❤

[@jessekujanen5970]

So much to remember, yet there are no easy ways to group any of these things together in an efficient way. - Other than memorising the main groups of medicines and their general mechanisms by heart. Which, takes a lot of time (1000+ pages of complex material in a month..)

[@heiitsme182]

Short and worth, subscribed!!

[@isaacb.m.5397]

💯 MORE VIDEOS PLEASE 💯

[@juli11051]

Thank you for the video. It helped a lot!

[@tigranhakopian6819]

Thank you for everything you amazing person❤

[@kristymallan2771]

Thank you for this! I found this so helpful :)

[@ikramzz701]

I love you 🥺🥺 You saved me

[@Zain.Basi1]

your videos are the BEST

[@vasanthv6850]

Very good lecture ....Can get a good clear informations... Very useful

[@ogoisliving]

These videos are awesome and very helpful. Please upload more

[@ahlamrashid3110]

Thank you sir 😊

[@hemapravallika55]

The question adrenergic antagonist asked in my examination for 10marks

[@vimaltiwari2372]

Best and interesting videos for revision .

[@UHFStation1]

Any videos on defibrillation? I am curious how the heart can get resynced. Of course when a person collapses, but also any electrical therapy to gradually nudge the parts of the heart back into timing?

[@mairakhan8586]

best lectr....very easy to understand.

[@m.k_69]

Thank you for your helpful videos and tips.

[@cyberteron]

Thank u very much I found it very useful

[@shahadms6991]

You’re the best, thank you!

[@queenmavichak6183]

Hello. Thank you for such i an amazing video. I'm doing research on Labetalol's and Beta blockers effect on blood vessels periperally. Labetalol is non-selective (B1+B2+A1), but you said that it causes vasodilation in blood vessels. I thought activation of B2 causes dilation in blood vessels? Activation of blood vessels causes vasoconstriction but Labetalol's ratio for affinity is 7:1 for B2 Versus A1. Could you explain further why it still causes vasodilation when it is blocking B2?

[@65nidheeshkumarprabakaramo68]

I dont know this but just a guess maybe due to this intrinsic sympathomimetic activity??

[@saqirashiq3109]

Great job..Want more elaborate discussion

[@eclkt]

Thank you for your teaching

[@shivangidesai5909]

awesome man!!!! I just love all your videos

[@reemmamdouh9311]

Excellent 👍 Please complete

[@vaishnavirasam5178]

Your videos have really helped me understand the concepts of Pharmacology..tysm...I have a request can you please make a video on anti-anginal drugs soon..?

[@bignumberlegendary]

thank you so much. please make a video on Enzymes as drug targets ,Renal physiology, Physiology of hypertension and blood and vessels

[@dalyanadhum9208]

Thank you thank you thank you

[@zlatinmotishev4199]

Мерси, братле. Бъди жив и здрав, и все такива клипове да правиш !!!