How do Beta Blockers Work? (+ Pharmacology)

[@walaa_abd9777]

1-carvedilol 2-b1 3-metoprolol succinate 4-d

[@sjlee9551]

Best ever among other beta blockers explaning videos. short and simple. sweet!

[@kayzee3966]

Thank you so much for making this video. I was having a hard time understanding how beta blockers work. I’m glad I clicked on your video. Within 15 min I was able to understand how they work. Your video is straight to the point and so easy to understand 👩🏻‍⚕️🙌👍👍👍👍👍

[@DrugChug]

Thanks for watching! Feels good to help! More videos coming soon!😁

[@bellefeu4933]

FUN TRICK: If a BB starts with A-M = Selective. If a BB starts with N-Z = Non-Selective (B1+B2). The only exceptions to this rule are Carvedilol and Labetalol (B1+B2+A1 non-selective), and Nebivolol and Betaxalol (NO release vasodilation for Nebiv, and CCB-like response for Betax). You now know effectively every BB receptor!

[@DrugChug]

That's an awesome trick! Thanks for sharing it with everyone!

[@medicallecturersforgraduat1417]

Plz tell me wt is AM NZ

[@andrewmulele9789]

@@medicallecturersforgraduat1417 its drug whose initials from start A-M,,i.e drugs such as atenolol,bisoprolol etc and those whose initials lie between N-Z eeeh

[@lauriebartling579]

It only works with the generic names though (eg Bisoprolol (generic name) versus Zebeta as its brand name. So don’t get confused. Great tip!!

[@krisannballin2291]

@@medicallecturersforgraduat1417 alphabet letters a-m

[@kathyTDP]

Please keep making these videos! I’m taking pharmacology this fall and I am already learning a lot.

[@DrugChug]

Glad you enjoy them! @Kathy Thang , And Yes! We will keep them coming!

[@TrustNJesusChrist]

Superbly well done explanation. Very informative.

[@DrugChug]

Thank you for watching!😁

[@sparker931]

As I'm currently on beta blockers this is very helpful. Now I know why I get so dizzy on standing up. Fine once I'm walking

[@eduardobravo-leon3894]

Thank you for another helpful video! Please keep making more!

[@jasminsaber]

I have a exam tomorrow morning you really saved me thanks a lot ♡

[@markrogers6778]

these are amazing for public speaking. Highly recommended!

[@reazhossain0083]

That was Great video about beta - blockers. In KZbin, i found only this video, which can be learned accurately and clearly . Thanks a lot for making this video.🥰🥰

[@chaewon-cf5eq]

Thank you for your video. Great help!! I am a student in Korea. I believe your lecture would be great help not only for me but also for students who live in korea. And I would like to translate in korean and share online. If it is OK, I would make sure to cite original source, your youtube channel. Hope to hear from you soon. Thank you!

[@PoiR-vy6nk]

So when adrenaline binds to alpha 1 receptor it causes vasoconstriction, did I understand right?

[@sachinthawanasinghe3591]

Great explanation about beta blockers😍😍 Thank you!!

[@BrandonD]

I use propranolol for anxiety and I had wpw I no longer have wpw

[@princeabdo5434]

Great video

[@Blinby]

Have been wondering forever why carvedilol causes a vasodilation. Nobody ever explained that sometimes BETAblockers can work on the alpha receptor as well. Thank you so much for this video!

[@DrugChug]

Glad it cleared things up! 😁

[@calumsingh9869]

Why are those three beta-blockers used in treating heart failure rather than different beta-blockers? Also great video, very informative and simple.

[@DrugChug]

Great Question! @Calum For a general answer: These 3 beta blockers proved to be superior in clinical trials for heart failure, and because of these trials, they are recommended. The only other thing is that Carvedilol has antioxidant effects, which help reverse structural damage to the heart, which would surely help our heart failure patients! Hope this helps!

[@calumsingh9869]

@@DrugChug Thank you, it makes more sense. How do the antioxidants reverse the damage? And can most structural damage be reversed using the mechanism?

[@Radoslaw731]

Bisoprololl has vasodilation effect aswel!!

[@ThePunisher0313]

How does B1 blockers cause hypoglycemia?!

[@abdullaanas2608]

saved my time so much !!

[@DrugChug]

Thank you so much for watching!😁

[@hariharanandsanthosh915]

Hi hello sir I have headache doctor refer to betacap 10mg I use this tablet but l have wezzing problem last 14 year so continue this tablet please reply

[@DrugChug]

Tell your doctor to change the Betcap to a SELECTIVE Betablockers. The medication you are taking is NON Selective, so it is effecting your lungs. Tell him to give you a SELECTIVE Beta blocker like Metoprolol. Your wheezing should go away, Hope this helps! Always refer to your physician first

[@hariharanandsanthosh915]

Thank You sir

[@julesviolin]

Blimey Eating healthy and keeping fit seems to be the priority here. I'm 60 and I think twice about even taking paracetamol. I don't even know what my doctor looks like ❤

[@momminmama3527]

Great explanation!👍🏾

[@DrugChug]

Thank you!

[@everonin5468]

I have a question, In what cases would non-selective beta-blockers be prescribed vs selective beta-blockers, given that many of the cases are heart-related issues? Thank you for your videos btw, super helpful and to the point, keep up the great work!! :)

[@DrugChug]

Great question! You have to understand that the non-selective are older drugs. This means some insurance companies want to pay for them first, because they are cheaper. So unfortunately money is a big factor in therapy. Also, some of the nonselective have benefits, for example: propranolol can be used for hyperthyroidism and social anxiety. Hope that clears some things up!

[@everonin5468]

@@DrugChug definitely cleared it up! Thank you so much for your help! :)

[@itsfatetraventure2335]

Non selective timolol somatol and propanolol

[@tarunnihlani1145]

Very well explained

[@abc_cba]

Hi, is it true that discontinuing Propranolol can result in abrupt heart attacks even at low doses like 40 mg ?

[@DrugChug]

Hi!😁 The risk will always be there when abruptly stopping any beta blocker. The risk is decreased if it's a lower dose, and a less duration of use (using it for 1 week versus 3 months). It never hurts to slowly taper beta blockers off!

[@MDALI-ur1fy]

Great explanation ❤

[@LucasSilva-kv3km]

Great video man Keep it up dude

[@DrugChug]

Thank You again! Appreciate the continued Support!

[@medicalinformation9035]

Where I found solve of these short quiz ? I want to make sure of the solution

[@zakiinaz9996]

Good presentation. Sir you have mentioned, in heart failure only 3 medicines ie, carvedilol bisoprolol metoprolol. So why nebivolol cannot be used bcz it could better replace carvedilol as the later even block beta2 receptor also. While the nebivolol do same as carvedilol without blocking b2 and since no lung issues

[@gcvoon286]

Can carvedilol 12.5mg give to elderly patients? Does carvedilol slow down the heart function n the dilation of blood vessel to cause lesser blood to kidney n causing trouble to the kidney as kidney receiving less oxygen? How long can this medicine given to elderly patient? As the lung receptors are blocked n causing less function to exchange oxygen, could this result the blood cell in the body and organ deteriorate because of less oxygen and nutrients reqiired? Also, since carvedilol put a brake on the heart function, could this eventually worsening the heart n causimg death to elderly? This video is great, excellent explanation. One more question, since carvedilol is an old medicine, does it still widely used?

[@antbbx3417]

So how would u safely dismiss taking any beta blocker without the risks???

[@systeme92]

Can you answer what blood vessels alpha blockers cause vasodilation

[@bijianto2745]

Thank you .good video. Can you tell me why patient is having bisoprolol and diltiazem together ?

[@huiyingng7305]

you're amazing! thank you!

[@akhonadraai5683]

Excellent!why carvedilol preferred in CHF?and how does rebound tachycardia happen??tnx.Njokweni(South Africa 🇿🇦)

[@osamayemenlover]

Great info.

[@himat9342]

Could you make a video on Prostaglandins please

[@DrugChug]

Yes, more videos are planned to be released in due time! Stay tuned!

[@savethesims2185]

I was put on propranolol because of heart palpitations caused by PVCs. It’s amazing how fast it works. I wonder what causes the PVCs. I always felt like I was having a panic attack, all day, every day for no reason. Not anymore 😁I usually hate rx because I always have the horrible side affects, but the only one I have with this is being cold because it slows the hr.

[@musikaaffection8570]

Thank you soo much ❤

[@Studypharmaa]

Informative video 👍

[@sarakhan-dl2lu]

Carvedilol & labetalol acts on b1 and a1

[@robertpvalentin]

Very informative

[@pujamirza5671]

What is proper method for taking a patient off beta blocker. Please answer me with graph . thank you sir.

[@sachinthawanasinghe3591]

Central nervous system side effects can be caused by some beta blockers lipid soluble, right?

[@jcarey1983]

Thanks!!

[@sumathyveeraragavan7788]

Thank you sir

[@muhammadhuzaifa8649]

Sir how come beta blocker block alpha 1 receptor ?

[@dr.bhupendrayadav1342]

we can also recommend arjunaaarista ayurvedic medicine

[@cdgates1]

I can't donate blood anymore because my pulse or heart rate is high. What is the best beta blocker?

[@zainul3515]

Which one beta blocker is best for atrial fibrillation???

[@DrugChug]

Hi Zain! there are many beta blockers that can be used for A Fib such as metoprolol, atenolol, nadolol, carvedilol, propranolol, bisoprolol. The best thing is to see which one your patient tolerates best

[@zainul3515]

@@DrugChug the artrial fibrillation is due to anxiety then which one will be best???

[@Imt8888_]

Can anybody please tell me why Carvedilol is used much than atenolo

[@DrugChug]

Because Carvedilol is a newer agent that has some antioxidant effects compared to atenolol. It has some extra benefits shown in clinical trials

[@Imt8888_]

Thank you

[@rinalditalanai4460]

good thsnk you dr

[@mrhappy500]

Sir I take Inderal for anxiety disorder, my doctor has advised me to stop this medicine gradually like 10mg twice a day for a week and then 10mg once a day for a week before stopping it. My question is that if I only take 10mg Inderal once a day whenever I needed can I stop it suddenly, and pls suggest which beta blocker will be suitable for my anxiety?

[@DrugChug]

Hey Ashu, yes you should slow down taking the inderal just like you said. If you decide to take it at times of need, it would be okay to take it once in a while without needing to lower the dose. However, if you are using it only for anxiety, you must take it 1 hour before an event where you may get anxiety. If you need a medication for anxiety, maybe talk to your doctor for an anxiety medicine. Because Inderal is usually only for blood pressure. Hope this helps!

[@mrhappy500]

@@DrugChug Sir, I'm grateful to you for your above advice and correct information. I understand that propranolol is basically used to lower the Blood pressure but its action of blocking beta receptors in the heart reduces the symptoms of anxiety. Which is great in dealing some social phobias like public speaking or an interview. I visited a psychiatrist (DM) and he suggested me to take SSRI (Selective Serotonin Reuptake Inhibitor) this helps in maintaining the proper level of serotonin in the brain and it cures my anxiety in the correct way.

[@DrugChug]

That sounds like a proper plan, I would work with your psychiatrist to develop a plan with an SSRI

[@mrhappy500]

@@DrugChug I have subscribed your channel to gain the correct and best information on drugs available throughout KZbin. Thx

[@alhaeri1]

good stuff

[@okomojelepo]

Does it help in decresing alpha c nuclein in brain?Intresting because lewy bodies

[@DrugChug]

Great question! I havent seen any research on this, but that's the beauty of medicine. We find more answers and questions over time!

[@okomojelepo]

@@DrugChug 👍

[@shibilanajeeb7149]

Supprbbb!!! N loved it

[@mehbubpatel8839]

My BP is 150/100 . Should have take Metoprolol ??? Is it risk any ? I mean side effect ?? Please reply...nice video 👌

[@DrugChug]

Your blood pressure is considered Stage 2 ( > 140 ) which typically means patients are on 2 medications. A beta blocker like metoprolol would decrease the blood pressure, but making sure you have a healthy diet is also part of the fix. Less sodium in your daily diet and healthier foods will bring it down. Contact your primary doctor and have this discussion with them, hope this clears some things up!

[@dr.bhupendrayadav1342]

please take arjunaaarista(terminlia arjuna) BD

[@dmana3172]

That would depends on your age and the reason your blood pressure is high. Do you have any chest pain or difficult breathing? Is your heart rate way over 100? If yes, then you do need to talk with your doctor to find the right medication to reduce that. Metoprolol works best for that. However, if you don't have any chest pain or any symptoms at all, then you probably don't need medications. Sometimes there's a good reason for blood pressure to go up when we are physically active or running alot or working hard, so you don't want to lower that because if you do and your blood pressure not high enough, you can get dizzy or fall and that's the side effect of blood pressure medications.

[@harrisengr]

Don't mean to preach because I have high blood pressure. I have typical systolic high blood pressure that happens after age 65. Sometimes jumps up to 145 even 155. This only happens when I eat a bit too much or a bit too much salt. The preachy part is that if you consistently have 150/100 you are eating too much and probably eating too much salt with minimal exercise. Sorry if that offends.

[@truehuman9449]

OMG i was given propranolol just for my anxiety and it helps. Why anxiety part is not covered in this video? Should i continue or switch to benzos? Which one is safe for anxiety?

[@annriah3051]

Good day. My doctor advised me to take propranolol 10mg once a day for about 1month for my chestpain. I’m now on the last 2pieces of medicine.. I’m just worried about the withdrawal syndrome after this.. Is it okay to stop it without tapering? It’s just a low dose anyway

[@mrstefon_8954]

So what about patients suffering from hyperthyroidism? Which beta blocker should I use?

[@DrugChug]

@Mr Stefon_89 Great question. If a patient has hyperthyroidism, then that would be the cause of the tachycardia. We would first try to treat the hyperthyroidism. Either with Iodine, or in some cases even radioactive iodine! If they must be on a beta blocker, Propranolol would be the preferred choice. This is because it prevents the conversion of T4 to T3 (T3 being the more potent thyroid hormone)

[@mrstefon_8954]

Drug Chug well I was on propranolol before for two days but I started getting Ectopic beats all of a sudden when the beta blocker wear off. So a doctor told me too take bisoprolol and I've been on it for two weeks, should I go back on propranolol? Is it safe too change from selective to non selective? By the way I'm on 20mg of carbimozole daily so I believe that helps with the T3 T4 issue

[@DrugChug]

​@@mrstefon_8954 The carbimazole is used to to control the thyroid hormone overproduction. If you were experiencing issues with propranolol, then it isnt recommended to go back to that agent. Bisoprolol is a good alternative beta blocker, yes it is selective for B1 (heart) receptors and will help with tachycardia. It is safe to go from non-selective to selective. The only issue would be if a patient had asthma, then we wouldnt want to give non selective because it may effect their sensitive lungs. (B2 receptors)

[@mrstefon_8954]

Drug Chug thank you so much for the info and I really appreciate the time and effort you're taking too explain this thank you 😊

[@DrugChug]

@@mrstefon_8954 No problem at all! 😊

[@darkmoon3646]

Freaking legenddddddddddddd. Thankssss mannn

[@batman_2004]

Use timestamps please.

[@carinapalme3439]

Hi i have anxiety. tierd Pain in my stomach and crasy drems and chestpain . I have 50 mg metoprolol can it givet me more anxiety? Dont feling good.

[@melissaballys820]

Same problem skip Inc blood pressure high 170/100 in June last year and skip one day when anxiety bad I couldn't breath I tried telling doc it has side effects but to no avail he say use it ok l feel relax but bad temper doc at hospital I must stop but I can come back to her but I need letter fr hospital to go back butanxiety I still have light in had

[@nagendrareddykarri]

How to stop atenlol

[@DrugChug]

You have to slowly stop the beta blocker over time. Ask your physician to help you guide on how to slowly lower your dose of medication over time

[@halimnsour6888]

NE doesn’t work on b2 receptors

[@DrugChug]

Hey Halim, this is a common misconception. In high enough levels of NE, it will indeed bind to B2 receptors. Here is a research article from the National Institute of Health (NIH) pubmed.ncbi.nlm.nih.gov/11734616/

[@professorh8398]

Yes, those pesky lions... olol!!

[@DrugChug]

Hahaa! I see what you did there 😉

[@user-we1ov5kq4f]

I got atenolol for social anxiety, wonder if a non selective would be better. I wonder if heart rate still stays low during exercise

[@gl00mi.u_u]

By the way, you misspelled Labetalol.

[@hayder_42]

thankssssssssssssssssssss

[@dalidali2757]

basically he is saying that all the drugs are a slow killer

[@ctre2]

Oh, lol!

[@Loraine07]

I hv this on repeat every time...u hv made my pharmacology content much easier to remember..can’t wait to watch your other videos ...

[@DrugChug]

Thank you so much for your support! More videos will be coming! :)

[@shohreakaberi2603]

Great video

[@zishanahmad7089]

1-A-M selective beta blocker 2-N-Z non selective beta blocker ( N se start non selective) 3-Nonselective beta blocker with extra property intead olol- lol present mostly except nebivolol tilisolol celiprolol

[@christellekankalian7824]

This video is by far the best video. It helped me so much with my exams in pharmacy school!

[@markrix]

Excellent information I wish these high-paid doctors would take the time to explain this to you they just are like here's a bunch of pills good luck

[@DrugChug]

Thank you for the support Mark! Appreciate the kind words😁

[@mellozz91]

This video was the most helpful pharmacology video I have come across! Thank you so much!

[@DrugChug]

Thanks for watching!😁

[@4evauniquelylatoya196]

Omg!!!! This was sooooooooo helpful!! I am a nursing student and was stressing over pharmacology but you my friend just made that stress go away!!! plz continue to post these very helpful videos PLEASE!! :)

[@DrugChug]

Glad the video helped!! More videos coming out soon!

[@4evauniquelylatoya196]

@@DrugChug yessssssssssssss!! 👏🏾👏🏾👏🏾💖💖💖💖🙏🏾🙏🏾🙌🏾🙌🏾🙌🏾😁😁😁😁

[@onedown9936]

you ever tried running away from a fast barking little chihuahua?

[@gloriac9994]

i am watching all your videos and seriously so obsessed and thankful i found u!!! you deserve a million subscribers. I swear no one can teach as succinctly as you. BLESS

[@mayahfawaz5307]

شكراً جزيلاً 🌼🌾 كان مفيداً جداً، أرجو أن تتم ترجمته للغة العربية قريباً

[@jamalsinjab5137]

tukram ainek madmozal Maya

[@HeadFullofDreams394]

thanks

[@fatihdarendeli6280]

hello. im 31 years old and because of palpitations and high heart beat rate ( usually between 95 to 110 while resting ) im using metoprolol 100 mg after im using this medicine the heart beat rate lowing down to 70 to 85 while resting. so how can i stop using this med ? like lower the dose to use 50 mg a week and then stop ?

[@zinthin8456]

How does constriction of the lungs decreases Blo0d pressure?I am confused

[@youjungjung9649]

This video is a LIFESAVER! Thank you so much haha I am studying for exams at pharmacy school!

[@jagjeevandeshmukh2250]

Nice explanation in simple way

[@DrugChug]

Hi Jagjeevan! Thank you for your support!!

[@reddysriram4080]

Best combination for 5mg amplodipine+ 40 mg proponol? please tellme sir.

[@muhammadhuzaifa8649]

sir i am having a hard time finding the mechanism how B1 causes contraction in the heart ? any recommendations any one plz .

[@medicalstore4413]

verysimpleway-explanation-witheasy-understanding

[@DrugChug]

Thank you for watching!😀

[@AkiRa-vm2nw]

I got 4 points on your quiz. 😊

[@DrugChug]

Woohoo!! Great job! @Aki Ra

[@Lazymath007_]

Are beta blockers good for ADHD?

[@mitersaw648]

Great channel. Can you do a video on Alpha Blockers

[@DrugChug]

Thank you for you support! @Miter Saw More videos coming soon, Alpha blockers are on the list to do! 😁

[@kavyasreeprakash6291]

Perfect vedio.... visualisation is amazing.. and easy to understand

[@ThePunisher0313]

From A to M its B1 (think of it as the first part of the alphabit)

[@panagvang1888]

Finally found the perfect video! You're a lifesaver. Thanks so much.

[@DrugChug]

You're welcome Missmaiv! Glad the video helped!😁

[@elf_meme9204]

ابن سينا💃🏻🙂🔪🔥

[@jagjeevandeshmukh2250]

What is role of beta blockers in Migraine

[@jonathanvasquez-mv9ic]

Dis pill doesn't like other az Prozac