PLP (Pyridoxal Phosphate) Reactions

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MIT OpenCourseWare

MIT OpenCourseWare

Күн бұрын

Пікірлер: 37
@tuffi1796
@tuffi1796 Жыл бұрын
Doing this as one of the mechanisms in 3rd biochemistry. Video is amazing, much better explanation of the steps than the prof in my class shows!
@salaheddinehouache1015
@salaheddinehouache1015 5 жыл бұрын
you gave a beautiful image of biochemistry. thank you Dr Bogdan and MIT crew for this course
@northamericanmuscle4499
@northamericanmuscle4499 Жыл бұрын
At 4:41 on the third structure PLP you can see you're missing a hydrogen on the lysine-bound enzyme that the base is supposed to be taking. Cheers.
@enricotortelli3642
@enricotortelli3642 4 жыл бұрын
You made me understand this process, thank you!
@DuyNguyen-qv3pi
@DuyNguyen-qv3pi Жыл бұрын
I only need a quick draw of a schiff base PLP bound enzyme with Lysine in the active site. But your overall video was excellent to the point that I need. Perfect! Productive!
@naliniseetharamiah9879
@naliniseetharamiah9879 5 жыл бұрын
Thank you for the clear explanation it saved my time. can you please make a video on pseudotransamination.
@Obamnaz
@Obamnaz Жыл бұрын
How are you counting the carbons to classify it as a 5' phosphate in PLP?
@ilimselyardm9698
@ilimselyardm9698 3 жыл бұрын
Thank you sir for this helpful video but ı like to mention at 1:40 all of the amino acids expect Lysine , Tyrosine and Proline are participate in transamination reactions forgive me if ı'm wrong sir. Thank you again may Allah bless you :)
@aaronadame1694
@aaronadame1694 6 жыл бұрын
At 23:14, shouldn't the N of the schiff base be deprotonated by water to complete imine formation? Also, why exactly is it favored for CO2 to deactivate rather than for the alpha carbon to be deprotonated? Wouldn't you achieve the same results with either approach?
@jamesjulius4804
@jamesjulius4804 2 жыл бұрын
In The Federation of St. Kitts and Nevis, PLP also means The Peoples Labour Party if one is dealing with politics and not Organic Chemistry. Therefore, citizens and residents of The Federation of St. Kitts and Nevis - TFSKN - I am kindly encouraging you to truly CAMPAIGN hard for and VOTE overwhelmingly for ALL 8 PLP candidates on St. Kitts and for ALL 3 NRP candidates on Nevis. The names of these eleven candidates are given below: Jacqueline Bryan in St. Kitts Constituency #1 Nubian Greaux in “ “ Constituency #2 Akilah Byron Nisbett in St. Kitts Constituency #3 Kendale Liburd in “ “ Constituency #4 Staschio Williams in St. Kitts Constituency #5 Dr. Marc Williams in “ “ Constituency #6 Dr. Timothy Harris in St. Kitts Constituency #7 Andrew Talbo Bass in “ “ Constituency #8 Dr. Patricia Bartlette in Nevis Constituency #1 Rohan Michael Isles in “ Constituency #2 Dr. Janice Daniel Hodge in Nevis Constituency #3
@yuvikayadav1203
@yuvikayadav1203 Жыл бұрын
Wtf dude
@rafiyamd1319
@rafiyamd1319 2 жыл бұрын
Please full name of pmp sir
@Hawkman6788
@Hawkman6788 5 жыл бұрын
This saved my life. Thank you!
@kaurkaur5119
@kaurkaur5119 4 жыл бұрын
Somebaody clear my doubt yr yeh base aur acid jo proton de bhi rhe hai aur le bhi rhe hai yeh kha se aa rhe hai yr
@Ericaa1523
@Ericaa1523 5 жыл бұрын
Literal life saver
@suhaibaziz4597
@suhaibaziz4597 Жыл бұрын
please what is meaning of H-B ?
@Ryan-jv9se
@Ryan-jv9se 6 ай бұрын
Base with proton
@ninaarudova30
@ninaarudova30 6 жыл бұрын
thank you very much ,really awesome
@bic1349
@bic1349 Жыл бұрын
Great video! Subscribed!
@asutoshrouta5724
@asutoshrouta5724 Жыл бұрын
thank you
@raluky44
@raluky44 6 жыл бұрын
what does the B in red stand for?? in the mechanism
@TGOMonsterr
@TGOMonsterr 6 жыл бұрын
B is a proton acceptor
@raluky44
@raluky44 6 жыл бұрын
@@TGOMonsterr thanks!
@kaurkaur5119
@kaurkaur5119 4 жыл бұрын
@@TGOMonsterr yeh fr base aya kha se yr
@라마-k6x
@라마-k6x 4 күн бұрын
14:20 part1
@aracelylicona
@aracelylicona 5 жыл бұрын
Thank you so much
@nahnahnah30
@nahnahnah30 6 жыл бұрын
awesome video
@dinaelfeky5527
@dinaelfeky5527 5 жыл бұрын
Thank You alot ❤
@choihojo
@choihojo 2 жыл бұрын
설명 진짜 깔끔하다..
@raniabelkheir67
@raniabelkheir67 4 жыл бұрын
merci 🙏🏻
@vishalithakur9255
@vishalithakur9255 2 жыл бұрын
Very hlpfull
@toanhien494
@toanhien494 2 жыл бұрын
merci beaucou
@FedericoBoccia-o4f
@FedericoBoccia-o4f 3 ай бұрын
Arnulfo Springs
@jamesjulius4804
@jamesjulius4804 2 жыл бұрын
The people of St. Kitts need ALL 8 PLP candidates to win. The people of Nevis need ALL 3 NRP candidates to win. ALL 11 candidates in a PLP-NRP government of alliance will work immensely hard with Prime Minister Dr. the Hon. Timothy Sylvester Harris to significantly accelerate and advance individual, family, community, constituency and national development that Prime Minister Dr. Timothy Sylvester Harris has started executing and implementing to improve lives and livelihoods of Kittitians and Nevisians. Kindly VOTE for the candidates of PLP on St. Kitts and please VOTE for the candidates of NRP on Nevis. Fully REJECT, NEGLECT and AVOID CCM, PAM and SKNLP. Leaders of CCM, PAM and SKNLP are traitors, betrayers, mega-thievesss and misappropriaters of public funds who are hungry for power but in the court of public opinion some are guilty of breaking up the UNITY Administration that was in government in The Federation of St. Kitts and Nevis while others are guilty of putting 17 % tax on us and putting us in the hands of the IMF before Prime Minister Dr. the Hon. Timothy Harris rescued us. Therefore, why do the CCM, PAM and SKNLP grossly incompetent political leaders want to go back into government where they were before they selfishly abandoned the institution and voluntarily came out or where they were before they were voted out of office? Think seriously about these salient issues - my family members and friends - and be ye convinced that it is BEST for each electorate in St. Kitts to VOTE for PLP and for each electorate in Nevis to VOTE for NRP. I thank you.
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