Poisonous Concoction Pathfinder: Full Guide (Path of Exile 2)

[@KassSaiYaJiN]

Full Written Guide HERE: mobalytics.gg/poe-2/profile/c97fe5f6-e198-4bd6-a0de-8141f695b166/builds/1295d809-9926-4838-8bed-e6694689aef6 I'm not affiliated with mobalytics so there isnt as much detail as my normal PoBs but should be more than enough. If you have any questions leave a comment. This is an unprecedented time in the history of PoE2. Being able to play this game where almost nothing is solved and everything is constantly changing is amazing. Please take this build as a base to build on, sure you can just 1 for 1 copy it but if you find something cool try it out. If you made it this far I hope you enjoy this build. This build wouldn't be nearly as good without the help and theorycrafting from commentors, so if you are one of those people, thanks for being willing to take the time to research to make a skill we all love good. Thanks for watching.

[@Bacon-egg-cheese]

My favorite part of this video is watching you hesitate to pick up any loot for like 5 seconds every time something worth picking up drops because of on death ptsd

[@KassSaiYaJiN]

LMAO at this point every mob has on death effects in my mind.

[@MorionAikanaro]

Which is fucking stupid. I don't understand why devs think those are engaging and fun mechanics. Even blizzard took most of them out of the game because they finally realized it.

[@jakecurry9526]

Thank you for the guide! This looks awesome and may be my first SSF project

[@KassSaiYaJiN]

SSF Will be pretty hard until you drop a widowhail but it might be possible to fight low lvl bosses with rarity gear and get one.

[@florian785]

I play SFF too. Level 46 Act 3 atm. Found a +3 Bow and a +1 Amulett/Quiver. Next Update will be the deadly Poison gem. I'm curious how far I can get. I hope they dont nerf PC, because in SSF you dont habe access to expensive gear. Only found 1 orange Item yet 😅

[@KassSaiYaJiN]

Unfortunately they over cooked it with the last buff so its pretty likely something will get nerfed. If they reduce it back to where it was its still a very good build

[@rhirune]

Thank you. Wanted to start a PConc since the update, but was waiting for your guide.

[@MrCiecio230]

thank you! Man i really hope your channel gonna grow!

[@KassSaiYaJiN]

Thanks for watching!

[@Maaster0]

Great video, thanks! I cooked my PConc Char up myself after latest patch notes were out since it looked really strong - and it is! Im running pure Evasion as defense rn (Wanna go Acrobatics when I get to ~lv90) and skip the Connected Chemistry Ascendancy node - with the tree, the Fine Belt and the Alchemist Boon stuff, I dont run out of flask charges in mapping, and rarely during bosses. Still struggling a bit on single target but I hope by the time I hit lv90 and get my 6th link, that problem will be solved. Overall I think hybrid Eva/ES will be strongest, since then we could run Grim Feast too to overcap ES, but imo that is pretty unneeded for mapping rn, and will also make the build a lot more expensive. I currently spent around 7 div I think in total, and 2 of those were buying Widowhail, trying to corrupt them for higher % lol. Will play around and keep an eye out on your channel to get more ideas!

[@_Khalmyr_]

ITS HERE, LETS GOOO!!!

[@xxCHAOTICKxx]

Just something to test out is a pair of boots that have the decompose skill on them i used them while leveling and it helped me not even worry about the ascendancy prolif and just rely more on plague since it was better anyway. Mings heart is cool but expensive if you want to look into that. I love this skill since it was introduced and tried many leagues to make explosive concoction work as well. I dont know why this playstyle and traps just speak to me. I will keep updating you on what i try if you dont mind.

[@GgGTeMpLaR]

Oh, does the % Reduced Flask Charges Used suffix on belt reduce how much you spend casting concoction?

[@KassSaiYaJiN]

When it's on a belt it does reduce the amount. I tested this with meginords girdle and it made the skill cost more.

[@minhocho5487]

I have been having incredible success with ci version. Since we can take the node that makes life flask work on es, it feels incredible not being bothered by chaos dmg

[@KassSaiYaJiN]

Does eternal youth regenerate all your ES when you use a life flask or just the amount on the flask? Also are you just pure ES and ES Evasion?

[@daxosmaxos1288]

Do you have a POB/Mobalytics for a CI version?

[@KassSaiYaJiN]

Looking into hybrid bases more they look busted. 1k evasion 350es is crazy.

[@minhocho5487]

@@KassSaiYaJiN I used es evasion hybrid with ghost dance. I feel immortal even during bossfights

[@minhocho5487]

@KassSaiYaJiN also near the passive tree you gave, there are a lot of evasion on gear gives extra es nodes. I dropped the 50%more flask for the 5 passives and dropped a few damage nodes.

[@loocid455]

Thoughts on contagion for clear in breaches and higher density places?

[@Ryan-jx6dq]

Did you use this build while leveling as well? or is there an easier build to level with before transitioning to this one? If so when did you transition? edit: nevermind just missed the leveling section haha will be looking forward to the video!

[@kylesteinhauser2535]

I think you can probably use a gas arrow/toxic growth build since a lot of the same nodes are used and same ascendency. Once you can get a widowhail and snakebite you can switch over

[@steff_ff3]

Great guide thank you!

[@seekup241]

Love the style of your guide! I just went path and want to give poisons a shot… if you have any tips for mid game/leveling would definitely check those out! Subbed!

[@KassSaiYaJiN]

Leveling a second character rn testing how it feels to level again with this skill in mind. Going to play a ton today and tomorrow so hopefully there will be a leveling guide monday.

[@seekup241]

@@KassSaiYaJiN Nice! Looking forward to it... right now im at the end of act 2 using gas/poison arrow with tons of physical damage and its pretty good, things die fast. Cant wait to get high enough for conc

[@GgGTeMpLaR]

Sorry, one more question. What determines how many links you can support concoction with? It won't let me jeweler it directly, is it just char level breakpoints?

[@KassSaiYaJiN]

Yep just char levels

[@Pandaxtor]

You get extra socket at level 40, 65, and probably 90.

[@Killer_Bee150]

Was trying something extremely similar to this but couldn't use pconc yet because i didn't have a good quiver (have a 241% widowhail) and the flask charges were too much to sustain. I'm planning on doing evasion es ghost shroud stuff with mine and was wondering if you could drop the mana flask charge ascendancy points and some of the damage points on the tree to get more evasion/es and the extra passive points on the ascension tree if it doesn't cost 4 points?

[@KassSaiYaJiN]

The flask ascendancy is also good for life flask uptime. Feel free to try it out tho

[@Killer_Bee150]

@KassSaiYaJiN Ah i see. I'm hoping that maybe removing a little damage on the tree to stack some more evasion and energy shield and going ghost shrouds eliminates as much need for a life flask so we'll see.

[@Hermes50837]

Hey there, playing smth similar, i played around with the Corpsewade boots for this, its insane for the clear. Just some input :) Linking the Decompose with Plague and Magnified effect basically auto clears rituals and breaches. The single target dmg of PConc is insane, but clearing lacks imo. So i tried them and they slap on that build.

[@Epiddemic1]

I'm playing Crit Pathfinder Poison Concoction and I Just hit 220k sheet dps, I've been going pretty sweaty... A couple of things I learned, Chaos Infusion is really good, potentially Original Sin is going to be good if you hit Tri Elemental flat on your quiver... Critical Damage and Crit chance and +2 projectiles on quiver is really great.. Projectile speed is the only decent prefix unless you are doing Original Sin. Corpsewade despite moving slow, is a great boot for doing t15 maps for QOL, it will demolish any circle event like ritual / breach and it helps cover ambush mobs. Jewels are really amazing. with the Adorned, it let's you REALLY ramp your crit multi and your dot magnitude.. Thanks for the tips on the support gems, had no idea the crit thing even existed.. Just finished the video I had no idea quiver bonuses on jewels were a thing! Awesome tips! Thanks!

[@NotSionnix]

how do u get enough crit to scale pconc? The skill only comes with base 5% crit chance which seems really low

[@Epiddemic1]

@@NotSionnix I took the 1% crit chance node for attacks on the tree, I tried Northbound but they don't work, I have 25% character sheet crit chance right now, but it's really more like 28% because I annointed 40% crit chance vs enemies with no elemental ailment. I have crit chance on Amulet / Quiver / Helm.. I could have more crit chance if I changed my passive tree.

[@Epiddemic1]

I also am not using the crit implicit quiver right now, I'm using the IAS with tier 6 crit chance / crit multi and 2 skills with proj speed.

[@RowanNo1]

Would really enjoy seeing you fight a boss or 2 for these videos. Great build

[@KassSaiYaJiN]

? Its at the start of the video. Unless your talking about pinnacles, I havent found them on the tree yet but the damage should be more than enough.

[@RowanNo1]

@@KassSaiYaJiN My god you're right. Sorry, was still waking up and must have glazed over it haha

[@bonelessthincrust]

what are your thoughts on the other concoctions, specifically fire/explosive? are they all just objectively worse than poison conc?

[@KassSaiYaJiN]

They all are good and this setup with a different tree will work with all of them (aside from the gloves obviously). Shattering is the one im probably going to mess with next. Freeze is really nice rn in poe2

[@bonelessthincrust]

@ cool thank you for the quick reply! I’m going all in on fire but I only just got my second ascendency so it’ll be a while before it’s at your level (hopefully)

[@stiltmouse]

What is your character sheet main hand hit chaos damage/crit chance/crit damage? Didn't see the skill sheet/character sheet come up in the video.

[@mortality-_-142]

What runes do you use on widowhail if any??

[@VildsiX]

Thank you, curious about passive tree progression :)

[@Wespa64]

An interesting unique that I love using for clear are the corpsewade iron greaves. While you do lose some survivability the added clear speed is big. Perfect for running lower difficulty maps.

[@KassSaiYaJiN]

For lower maps bursting plague is more than enough. 10% ms boots to do lower level maps faster kinda seems counterintuitive.

[@Wespa64]

The clouds are big and it gets those strugglers that were just out of range of bursting plague making my clear more laid back. But yes for, pure efficiency those extra 20% ms are better.

[@immort]

im playing pconc currently lvl 90 and im using plague bearer for clearing. Just throw once pconc and use plague bearer ---> ofc link magnified effect with plague bearer. Be sure its lvl 18 AT LEAST. if not it deals too low damage. physical mastery gives +1 lvl

[@GgGTeMpLaR]

when I plug in Deadly Poison, it shows as a dps loss? Is that because the initial hit losing 25% is a bigger dps loss than the magnitude getting a 75% gain until a certain threshold is reached?

[@KassSaiYaJiN]

I don't think poison magnitude is being calculated correctly for the tool tip. 75% more is very good even with the downside.

[@陈祥智-y3v]

What’s important is the poison damage instead of the dps shown in the front. Press the arrow button located on your skill to see your poison damage is higher when you put deadly poison

[@THETunaCasserole]

Nice guide, man! What is your evaluation of the Flurry node? I figured it didn't make sense to take as 25% reduced dmg seems pretty huge...or maybe I was confusing reduced with less and 25% reduced isn't actually that severe of a penalty

[@KassSaiYaJiN]

Reduced isn't less it's not that big of a damage loss. Reduced = negative of increased

[@THETunaCasserole]

@@KassSaiYaJiN Makes sense! Another follow up question on this -- do you know for sure if "while unarmed" applies here for the + AoE? We are technically holding a bow + quiver but dealing unarmed damage

[@KassSaiYaJiN]

The unarmed attack speed definitely works. As for AoE it's hard to tell idk if the explosions are actually scaling and others have said AoE might not be working. I wouldn't be surprised if maybe the flasks itself were getting bigger but the explosion wasn't or something (probably a bug).

[@Critimuscu]

Is Commorbity negativ effect works for you? with and without, the tooltips show the same poison duration for me

[@KassSaiYaJiN]

The tool tip is bugged it doesnt show the loss in duration. I'm pretty sure it still adds less duration but it could just be totally broken (Early access xdd). Based off of anecdotal testing it does "feel" that comorbidity is reducing the duration but I could be wrong feel free to try it. TBH it wont make that big of a difference either way.

[@Wheathn]

I went with the lightning version with the new electrocute clusters. Still need to find the int>LDmg gloves though (SSF). But it may have more potential imo.

[@KassSaiYaJiN]

All concoction skills are good rn. I don't see a reason why they need to compete. Shattering has a ton of potential as well.

[@iceiceice914]

Hi, i’m still confused about the crit. How does crit work for poison? Will all poison crit if the poison concoction that applies those poison crit? Or is it simply to calculate each poison hit? What’s the basic crit chance of poison? Thanks

[@KassSaiYaJiN]

It doubles the magnitude of the poison. Basically if you hit for 100 your poison base damage is 20 now if you crit you hit for 200 instead so now the base damage is 40. The poisons itself don't crit but the main damage that the poison is calculated from does.

[@detoxicfy]

What runes do you put into your widowhail?

[@KassSaiYaJiN]

Currently my widowhail doesnt have sockets since it was corrupted without it to +257%. But stretch goal will be +15 spirit soul cores but they are 150ex each.

[@Cuervo-Exiliado]

Thanks! Im doing a poison PF and Im looking for variants to take a good single target skill.

[@MorionAikanaro]

So.. its basically the end game version of the gas arrow builds.

[@lylechaussette9559]

I also hope we will have POB soon, because i want to know if my magnitude node (south of the tree) is better or no than Projectile you take. Also for the +2 poison stack cs the chaos gem

[@KassSaiYaJiN]

Yeah it will be really nice to have more concreate answers. I want to know how impactful things like increased attack damage is since the hit only is 20% of the poison damage its hard to know if its worth scaling the hit vs poisons in general.

[@lylechaussette9559]

@@KassSaiYaJiN We can also assume at 6 link, drop the glove, take a big defensive gloves, take poison gloves and the unique ring who give u 40% chaos damage (With some ES stacking it would still tank a lot)

[@prahaladgiridhar6788]

Gear looks reasonable, any cost estimate for starting out?

[@KassSaiYaJiN]

You can go super budget like literally under 10 ex just need widowhail and a +2 quiver.

[@prahaladgiridhar6788]

@@KassSaiYaJiN Character created see you in a few days

[@Tropicocitwo]

Have you tried using Plaguefinger gloves?

[@KrayZee33]

Is it possible to make this work with energyshield/evasion? Energyshield scales so much better than life. And Grim Feast doubles it. Some nodes on the passive tree are close by too (monk)

[@KassSaiYaJiN]

Thats probably the end goal for survivability, that or CI also looks good.

[@user-cz1ex7kf2g]

How does the Flurry notable work? It says 25% reduced unarmed damage, does that hurt the DPS?

[@KassSaiYaJiN]

Reduced isnt less (less is a multiplier reduced is just -25% increased) it does lower "damage" but the attack speed from that node is very good. Its a big dps gain.

[@user-cz1ex7kf2g]

@KassSaiYaJiN oh that does seem really strong then. good call

[@kavynizde]

why critical damage bonus rune in bow doenst work for concotion?

[@gnptldr]

Do you have any ideas how to improve Pcon Quality?

[@ShadowXSAP]

running this same build using a annoint for 2 handed mauls as 1 handed, requires triple stats (merg girdle gives a ton of str) with a shield and the node to double block chance but take 50 pct of the damage still, that with 85 pct evasion and max res makes you invincible, the 2 handed does contribute to damage still (not sure if its a bug), but my damage is no where near yours.

[@softcoreplebgaming9674]

Nice. 1000 builds in the past 2 days with this. I'm playing this in ssf. Invested everything i have in this. So when ggg will nerf this what will I do ?

[@wuzat-]

could you do pconc with Acolyte of Chayula ? or pathfinder the only viable option ?

[@KassSaiYaJiN]

Its a pathfinder ascendancy, it can be used with any other ascendancy.

[@zackariahp1873]

Ive got 300% quiver bonus so far and it absolutely destroys, i can only imagine what 400% feels like. Im saving for it but its so expensive. P conc is so much more fun than gas arrow, gas arrow is very brainless and unsatisfying. P conc slaps

[@KassSaiYaJiN]

I feel the same way, gas arrow felt like cold dot. Pconc feels like an actual poison build. Imagine adorned with 15% bonuses from quiver jewels. 30% per jewel slot the numbers could just get insane. Like 500%+ is possible.

[@truedps8]

For Widowhail is 250% a breakpoint? Does it make it +7 instead of +6 levels?

[@KassSaiYaJiN]

every 50% is a break point

[@easylivinglife6284]

Since I consider this skilled solved by now. But I have always played poison conc as a unarmed shield for extra defense and survivability- and maybe you could also use quaterstaves because the unarmed damaged could be significant- idk maybe there will be a hand of chayula giga curse build that scales unarmed damage in the future?

[@Koujimaru]

Do you know how to add quality to Poison Conc?

[@KassSaiYaJiN]

It's bugged.

[@MrCiecio230]

do i need 3th ascendacy for this?

[@shooterpep7588]

Where do i find poisonous concoction is not on my skill tree

[@florian785]

Pathfinder Ascendancy 🤙

[@cat-anchovy]

why not gloves for magnitude from hits ?

[@KassSaiYaJiN]

If you are talking about plaguefinger it does nothing unless you get a ton of flat ele damage on the quiver. It could be good but snakebites are also very good.

[@PNKim_]

Gas arrow has way better clear but single target damage is better with pconc

[@Skehit]

pretty sure they will fix concoctions skill to work only unnarmed like in poe 1

[@Duuude9448]

WARNING DO NOT START THIS BUILD will be nerfed 1000 % killing uber bosses in 1 sec ! Streamer Rueroo sneaching now on this build and hyping this up showing how its broken

[@KassSaiYaJiN]

Its early access man things will get nerfed, The only thing that matters is how big of a nerf will happen. You can always just play gas arrow with a similar setup its not that massive of a deal if it does get nerfed.

[@borremoonkey]

😂 dude is acting like you’ll immediately turn a switch to stop having fun if they do nerf it

[@Kuorria]

FINALLY HERE LETS GOOOOOOOO

[@SpicyD_]

Trying this in ssf, lets see if widowhail is rare

[@lylechaussette9559]

I switch 2 day ago, good damage, not so op vs some build who can deal 3/5 m dps all good

[@TorbLlorts]

so in poe 2 proj dmg increases poison dmg? weird.

[@KassSaiYaJiN]

Technically yes but only the magnitude of the poison not the poison itself.

[@TorbLlorts]

@@KassSaiYaJiN how do we know though? Im trying to level up with pconc but need more flask charges indeed

[@gatitoblade]

i had a 250% widowhail and corrupted it to 141%... we go agane 😂🔫

[@NguyenPhong-yx3yd]

Inevitable Critical really? that support is so bad even the Chaos mastery gem is better (+1 chaos skill)

[@KassSaiYaJiN]

Crit is double magnitude. It's very strong. For endgame bosses chaos mastery is used instead of plague burst.

[@mydogdunk8471]

Increased damage with bow skills on quiver affects pconc. Don’t miss out on that huge increased damage.

[@KassSaiYaJiN]

If that is true then thats obviously a bug. But pretty nuts if it actually works, idk if we really need more damage but could be something to try.

[@THETunaCasserole]

@@KassSaiYaJiN I had this same question as I saw another video on pconc that mentioned this, tested it myself and it does seem to work though I don't really see any reason why it should. Probably a bug, yeah

[@KassSaiYaJiN]

@TheTunaCasserole pconc doesnt even have a bow tag so idk how it even works tbh. Theres probably other things that are also adding damage to it randomly then. Hopefully that gets fixed and maybe it will bring the power level down enough that other nerfs wont be super heavy handed.

[@HK41251]

@@KassSaiYaJiN Yep it's definitely working. I've done the testing with a 44% mod and raw DPS boost without any supports was 68% with 370% quiver effect. It's likely coded as "damage with projectiles" rather than "damage with bows". Not entirely certain if it's a bug meaning it SHOULDN'T work, or if it's intended and the modifier text is wrong.

[@HerrmDogg]

Reallyyyyyyyyyy looking forward to the leveling video guide!!!

[@TheMrApotamkin]

I'm waiting for all those cry babies in global chat after they fix bow thing for PConc in 1-2 weeks :D

[@Killer_Bee150]

I mean if they do that pconc as a skill will literally be useless as there's next to no scaling for it otherwise.

[@masonhales]

woah wtf widowhail got nerfed? Only has 250% max scaling instead of 300%?

[@KassSaiYaJiN]

Its always been 250% baseline a corrupted version can get to 300%+ (highest I've seen is 305%)

[@vicocloutier9607]

=)

[@matrixxstar1325]

That's a bad guide. Where is corpsewalker for the clear, and why are you taking Connected chemistry as ascendancy, only for sustain mana flask , really? You can easy sustain it with Fine belt, Alchemist Boon , and flat Gain charges per second on mana flask itself, overall it will be more than enough to sustain your flask , and you dont need to pick mana flask nodes in a tree . And im not even talking about CI setup , which will have more survivability ...

[@KassSaiYaJiN]

Classic.