Polyclonal antibody

[@pritiswain3718]

Polyclonal are those when serum contains different ab against single antigen for different epitope and each one is specific for one epitope. I think you might have told unconsciously that one ab recognise different epitope.

[@tusiye4356]

you are really simplifier, and recently detected your Chanel accidentally, and it's now one of my first sources for referring when things go tough in biology . Thanks

[@shomusbiologyofficial]

Thank you so much for appreciating

[@sydneysimukoko]

Indeed the man is very great, I've been watching his videos since my 1st year, I'm now in 3rd year doing Veterinary Medicine at the University of Zambia 🇿🇲.

[@michaelleischnig6435]

I read this remark like 2,3 times here (@MegaMie77, @spandita roy), so for clarification, as I understand it: If you inject a specimen A (let's say a mouse) with a specific antigen, this host will maturate lymphatic B-cells into B-plasma cells (through the known pathway macrophages - dentritic cells - lymphatic T-cells - T-helper cells) that produce antibodies against it. These Ab can be extracted as a serum. Normally, an antigen has more than one epitope with which an antibody can interact. Therefore, the extracted serum/mixture would contain different antibodies against the antigen, (as a whole) so-called polyclonal antibodies. Still, each of the antibodies can only interact with one specific epitope expressed on said antigen. Hope that helps/is at least accurate :D

[@Thats_my_tale]

U explain really great I have 10 days for my enterence exam and with your videos i have completed so many things in less time and u explain in such a simple way tht it's really easy to remember

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@spanditaroy9973]

Polyclonal antibody is actually collection of antibodies produced from different B cell lineages that's why they can interact with different epitopes of same antigen. Am I right?

[@pritiswain3718]

Yes

[@vijayag1957]

Yes

[@Talentcreationndimagination]

Sir u are really the great . If I will meet u then I will do the robbbery of ur mind😎

[@shomusbiologyofficial]

Ha ha

[@rahilabbas643]

Love the way... You explained sir... Hats off Sir jee

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@Semsempharma1]

God bless you , you explain in very simple and clear

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@maryamzulfiqar9390]

u helped me teach better understanding of immunity and vaccines to my students.. thank u

[@shomusbiologyofficial]

You're welcome. Glad you like it

[@anyannoaxom6290]

Your insight is now becomes applicable to understand Antigen against covid 19. Thanks for your anticipation years back

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@bhargavkbh5739]

Specificity and affinity these are the unique words used in this video ❤️

[@shomusbiologyofficial]

Thank you. Glad to hear that you are getting benefit from the lectures

[@alexandraandronik7479]

Thank you!!!!!!!❤

[@shomusbiologyofficial]

You're welcome

[@jyoti2298]

Thank you sir for such a informational vedio .......❤️

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@mayukhroy5393]

Thank you Sir, this video was helpful

[@zaheeriqbal3377]

Ur great sir g

[@shomusbiologyofficial]

Thank you

[@emamulhassan3955]

So helpful❤️

[@shomusbiologyofficial]

Thank you

[@rinaevasoamamy8493]

thank you for the explanation

[@rajyalakshmi902]

Sir u made many scientists lecturers 🙏

[@shomusbiologyofficial]

Thank you

[@soumyaranjanbarik923]

Thank u so much sir... I got complete idea about it....

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@fundamentalzoology7131]

Nice lecture sir. Easy to understand.

[@MegaMie77]

You have the general idea right but off when you get into specifics. For a start, there is no such thing as a polyclonal antibody. It would be synonymous to saying someone has multiple birth mothers! Impossible right?! Polyclonal is the mixture of antibodies from multiple cells before clone selection. Yes, the mixture will target different epitopes but on a micro level, each antibody can only be specific to a single epitope.

[@qigong1001]

No, you can have cross reactivity.

[@farheenbegum6784]

nice...explaination.and thank u...

[@shomusbiologyofficial]

You're welcome

[@sadodexter4228]

Excellent work

[@shomusbiologyofficial]

Thank you

[@swetambari95]

Very informative 😊

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@ajuljose9064]

Thank you

[@shomusbiologyofficial]

You're welcome

[@triptyayesha8845]

Please make a video on antibody humanization

[@godslave85]

thank you very much

[@karnailsingh2629]

Sir Again a short lecture about polyclonal and monoclonal Ab in hindi

[@shomusbiologyofficial]

Coming soon

[@ullaskotihal1911]

Thanks bhai

[@shomusbiologyofficial]

You're welcome

[@ullaskotihal1911]

We wanna meet you. Where are you from?

[@Dr_Syed_Ali_Rukh]

Shabash

[@silpasumandebasharma273]

Sir ..is there any book in which this topic is present

[@shomusbiologyofficial]

Kuby immunology

[@silpasumandebasharma273]

@@shomusbiologyofficial thank u ...and for SDS page which book ...?

[@ssubbiahsubramanian4353]

Sir is plasma cell and mast cells are one and the same

[@wasimakram6892]

Good

[@shomusbiologyofficial]

Thank you

[@jasmint7822]

Nice

[@shomusbiologyofficial]

You're welcome

[@manasasanikere91]

Sir could you please make one vidio about photo bioreactor

[@ullaskotihal1911]

Fan from Karnataka 😍 We wanna meet you

[@shomusbiologyofficial]

You're welcome

[@obiwan922]

You are saying, a polyclonal antibody is the one which can bind with different types of epitopes? 3:55 . I didnt get this part. (Maybe i learned wrong then!)

[@fundamentalzoology7131]

Different epitopes means different regions of the antibody, those make bond with antigen. For better understanding you must know the molecular structure of the antigens.

[@mittukoshy1986]

Excellent way of teaching. Even a person from non biology background also can understand this well.

[@zakiasultana2986]

Why we can't use a single antibody as monoclonal antibody from the polyclonal antibody mixture?

[@kopiyofred2619]

Thanks for your clarification,

[@whiterose5206]

thank you for your easy explanation. big help here

[@tanzeemazeeza.s9589]

your lectures are very useful sir thank u so much

[@timfitzgerald4079]

Excellent presentation and explanation of mono/polyclonal antibodies..👍👍👍

[@KousikiChatterjee]

Is only one B cell producing different types of antibodies?

[@sunilpaudel6013]

thank you Sir......Now i'm cleared about mono and polyclonal antybody........thanks

[@maryamamer5295]

❤❤👏

[@shomusbiologyofficial]

You're welcome

[@waitspankaj]

thank you so much.. sir..can u post a video on nano technology and tissue engineering in medicine..

[@shomusbiologyofficial]

+pankaj k I will try to post videos on that topic. Thank you

[@beenaasokan8569]

sir can you post a video on vaccines and classification

[@shomusbiologyofficial]

+beena. r it's already there. You can find it 8n my channel

[@bublymallik8930]

The audio of this vdo is not good...but the lecture is good 👍

[@siprachauhan1958]

Hindi me samjhaye sir g jayada samjh aayega or like v milega

[@shomusbiologyofficial]

Like nehi chahiye

[@aashikas3859]

Sir if we use tumor cell for multiplication is there any chance tumor formation

[@sarinasarina3973]

thank you、 sir。how to choose the primary and secondary antibody？

[@rucha3428]

thank you sir. i have a doubt. why antibody produced are type of IgG only?

[@AnkushSharma-zv5hv]

actually polyclonal antibodies are mixture of monoclonal antibodies....which bind to specific epitope but since they are mixture...so they bind to various specific epitopes.....

[@kuisoomnizar7074]

Nascarwalu phuk no bos tu

[@suniltripathi5394]

totally wrong concept

[@shomusbiologyofficial]

Why?

[@layjain7097]

Nice

[@shomusbiologyofficial]

You're welcome