PrEP for HIV Prevention: The Best Worst Kept Secret | Raphael Landovitz | TEDxUCLA

“Preventive Medicine” has arrived for those at risk for HIV. New medical strategies are available to help prevent HIV from being transmitted. As futuristic as this concept seems, it is part of a preventive revolution for medical care - where an “ounce of prevention” may be worth more than a “pound of cure.”
Raphael Landovitz’s clinical research career focuses on optimizing the use of HIV antiretroviral therapy for both HIV treatment and HIV prevention.
Dr. Landovitz was trained at Princeton University and Harvard Medical School. He completed post-graduate training in internal medicine at Brigham and Women’s Hospital (1996-1999) and Infectious Diseases and HIV Medicine at Brigham and Women’s Hospital and Massachusetts General Hospital (1999-2001). He works in the DAIDS-funded AIDS Clinical Trials Group (ACTG), HIV Prevention Trials Network (HPTN) and the NICHD-funded Adolescent Trials Network (ATN), and serves as the Clinical Research Site leader of the UCLA CARE Center Clinical Research Site for the DAIDS-funded networks. He is the principal investigator of a multisite PrEP demonstration project in Los Angeles County, and the protocol chair of Phase 2a and Phase 2b/3 studies of long-acting injectable PrEP using GSK1265744 (cabotegravir).
This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at ted.com/tedx

[@Winfury-thunderfury]

I started prep recently and couldn’t be happier! Def recommended! I’m 19 and so happy medical science has made it so far for someone even as poor as me can afford this level of protection, thank you scientists for all your hard work to make such huge strides in the past decades!

[@BigBadMF43]

does it help help prevent flu, common colds and covid?

[@Winfury-thunderfury]

@@BigBadMF43 nothin but vaccines help with that brotha, but i will tell you PreP made me lose a lot of weight

[@BigBadMF43]

Lose weight? Why would it make you lose weight? I'm a bodybuilder and don't want to lose weight. @@Winfury-thunderfury

[@rockermack7903]

@@BigBadMF43 one of the common side effects

[@BigBadMF43]

@@rockermack7903 I have been taking it for past few months and no effect on my weight. What does it do? decrease your appetite?

[@mimimariah8]

Crazy 6 years later and I’m still educating people on PrEP

[@DamonLJacobs]

Outstanding description of PrEP and the power of this change.

[@JakeMossop]

I agree!

[@maym3456]

Well said. A much needed talk! Thank you for all your support and advocacy.

[@cmj9151]

He’s a very good speaker. My professors need to take some notes from this Doctor.

[@davidjones-wy3ln]

prep is bad, it encourages bad behavior and explodes the rates of sti's

[@johansm97]

@@davidjones-wy3ln that is still cheaper than long term hiv treatment

[@anioevsoccer]

I take a descovy every day. For almost three years now. I'm HIV negative. I am so lucky to live in these times.

[@zolabison2744]

Needed to see this. Thank you

[@ronnoco1110]

This talk needs to be seen by all! What an amazing medical breakthrough. Thank you for your continue knowledge and support to the field of HIV and AIDS

[@JakeMossop]

Yes, we should be thanking the researchers for their hard work! I agree.

[@davidjones-wy3ln]

prep is bad, it encourages bad behavior and explodes the rates of sti's

[@charlenehermione6509]

All thanks to Dr Abiola on KZbin for curing me permanently from HIV with his herbal medicine

[@itzrlymeman]

This video changed my life and I’m thankful I found it

[@mzukisindzipo7495]

There was a time in South Africa (1990's) that we had a president who argued (academically) that HIV does not cause AIDS. People who needed treatment did not get it during that time. They died from AIDS related diseases. South Africa learned a lethal lesson and now not only admisters ARVs (saving millions of lives) but also has rolled out PREP (preventing millions more from being infected). HIV denialism should be declared a crime against humanity!

[@Westhamsterdam]

Come on, how comes African HIV/AIDS is totally different from western AIDS? Where is KS/PCP in African AIDS?

[@boogeyman2868]

i think ignoring the science and adjusting statistical numbers on global/national scale should be declared a crime against humanity.

[@JaesadaSrisuk]

Circa 2021: there are now Truvada and Descovy commercials on public tv: so while the ethics of promoting drugs via commercials may be questionable, the knowledge about PrEP has come a LONG way!

[@ariadnelopez430]

This is a great description of HIV and the different methods that are being developed in order to prevent it. It's amazing to see how far medicine has come since the AIDS epidemic back in the 70's. Unfortunately, the stigma behind HIV has not gone away completely, but the hope is to bring the truth to light about the importance of primary prevention. Thank you to scientists and researchers like you who continue to make meaningful contributions to the world.

[@senthilkumarpanneerselvam6657]

He spoke from his heart lovely

[@justcalledkatie]

says a lot about the promotion about these important medications when i found out about prep from fanfiction

[@isabelapeluso9275]

Same!

[@Lovelypanacea]

Thank you for supporting the delineation of this vital information!!!

[@ftw7813]

Prep does not dismiss personal responsibility.

[@DaRyteJuan]

Hard to believe this talk was given 7y ago. I only just learned about PrEP about a month ago.

[@breahsaldana9251]

excellent presentation!! He's absolutely right we do have lots of ignorance in the world still in 2018 ..I'm hoping people are listening to him and spreading the word to Drs that need educating ! Thank u so much for that wonderful and educational speech.

[@inder19852000]

In Germany, you get PreP now for 50 Euros. I have started trying since 2 days. I have health control by doctor after 2 weeks

[@yurionice8666]

Nimmst du das Präparat noch? was sind deine Erfahrungen?

[@santhuviran4853]

Hi, Hope you are doing good. If you don't mind, could you tell me if you faced any side effects on liver and kidney in long term? I'm planning to start prep soon

[@chinneynz7861]

This is wonderful!!!!! As a nurse who just started working with HIV/AIDS , I find this talk to be a very helpful tool in my community outreach for HIV prevention. Nice job, doc!

[@jasonmanning6317]

There’s a clinic in Nashville where I’m able to get tested and get PrEP without paying a single dime. And they mail it to me.

[@ladyboyleelee]

I go there too!

[@tradingbull007]

Please mention there name and address

[@charlenehermione6509]

All thanks to Dr Abiola on KZbin for curing me permanently from HIV with his herbal medicine .

[@dama_shares]

Thank you for sharing this information. This is the first time that I am learning about Prep.

[@ken4722]

Been on Prep for a while now and I have been so confident about my health status. When I started taking it I told my friend about the drug and he didn't want to hear about taking a drug when you are totally fine. A few years later he caught the virus. Regrets never listening to me cause I knew we needed the prevention having been in these streets hard lol

[@charlenehermione6509]

All thanks to Dr Abiola on KZbin for curing me permanently from HIV with his herbal medicine

[@ken4722]

@Abhadi asernal please stop misleading people. This is not a disease we should joke about.

[@zolabison2744]

I needed to get this kind of assurance. Thinking of starting on prep too. Thank u. ♥️♥️♥️

[@oirow]

Prep is not 100% safe… and does NOT prevent from STD’s…

[@MohammedLiswi]

This is a very informative and inspiring speech and still relevant in 2024!!!

[@thabopossa951]

From south Africa thinking about using Prep. Worry about side effects & the fact that everyday I must take a pill.

[@infledermaus]

The "shame" goes straight back to the US's Puritan roots. I really think that this protocol could ends AIDS. And wouldn't that be something. I came out just as the AIDS crisis began. I would love be to see it end.

[@mikemush9741]

Fantastic presentation. Thank you so much. for such outstanding information, but more importantly for helping get the word out that there are options.

[@vacationjon67]

Excellent presentation, well spoken, educated and a great resource. Thank you Dr. Landovitz.

[@TheBrandonWeidner]

I never knew about this before today and I agree as a preventative it sounds great and people should use it and know about it!

[@JakeMossop]

The power of information! Glad you learned something!

[@ppmireless]

yeah... ahaaa.. learn the opinion of peter dousberg about this.

[@charlenesgubudu3105]

Honestly, I didn't know about this and I am glad to have a Tik-Tok account, because that's where I had to learn about it. In the process I had to dig further by coming across your video. Thank you.

[@kmnchrs6961]

Checked the date this video was released and was shocked. Heard about PrEP last week on a radio but didn't think I heard what they were saying properly cause I didn't think this was possible or that someone can actually trust this. Randomly came across it when I heard read about some people being naturally resistant to HIV. Here I am in the year 2023 and this has been out there all along but I had never heard about it; only knew about PEP which I also didn't trust could work until a friend of mine was on it. Really important talk!

[@timothykuria8691]

Did that friend of yours come out negative afterwards

[@kmnchrs6961]

@@timothykuria8691 Yes he did, but gotta point out that he suspected the girl to be seropositive based on the people she was messing with, he had no proof she was.

[@timothykuria8691]

Okay thanks for the reply

[@madagascar71]

Congratulations Brother, keep spredimg the message.👋👋

[@johnt6022]

Excellent presentation. I can't wait for prep to be given IV once a month...

[@keithparkhill4218]

Yep kidney failure at twice the speed.

[@JakeMossop]

is that something that is going to be done?! interesting?

[@ricardorodriguesrr18]

Keith Parkhill why r u saying that?

[@scotttrent4721]

Because he has no idea what he's talking about.

[@RbnHrtzll]

It's true that patients might need to educate their doctors, especially in conservative parts of the country. I live in Kansas, and my doctor wasn't familiar with pRep when I asked for a prescription. However, she got on board and now discusses it with at-risk patients.

[@charlenehermione6509]

All thanks to Dr Abiola on KZbin for curing me permanently from HIV with his herbal medicine .

[@MrK3vinR]

Well spoken and could’nt have said it better. Thank you.

[@jeffamunoz]

*Descovy is incredible!*

[@humbertoortiz-flores8081]

I started taking it 5 days ago, no side effects, did you have any side effects?

[@klondike99]

Why would he be against the the drug manufacturers advertise it on TV as long as they get the message out?

[@DaniTelevized]

This was an amazing TED talk very informational and im so excited about the new medicines and methods that are coming to prevent HIV.

[@chesshi8211]

2024, first time heard about HIV prevention.

[@vincentavezaat]

I read about it the first time on profiles on Grindr. So PreP is indeed almost a secret.

[@isabelyube3260]

Such a good doctor and well spoken thanks

[@valentinomiller6251]

Notice how he circularly-talked around the question "Why haven't I heard about it?"; he still didn't answer it.

[@anthonydavid5121]

Because he's asking a rhetorical question, not a literal one.

[@kookoo9958]

PrEP was available way before this. The government just didn’t care to regulate drug companies who were busy making . Tragic. India makes HAART medication for $1 a pill. The USA charges $30 a pill. Pathetic.

[@Jake-lt8cz]

We can get it for free, thank you ryan white organization.

[@biggityboggityboo8775]

Condoms break too, I had that happen just the other day. Going on PEP is a huge annoyance. I'd rather just be on PrEP.

[@9999_damage]

same thing happened to me recently, decided to take all measures I could and take PEP just in case. I am very lucky to have had PEP available, but being on PrEP could make these kinds of accidents that much less scary and stressful, and be there to more immediately protect the body from infection

[@arravinnathsubramanium7707]

Hi I'm currently on PEP. May I know whether it was effective?

[@richarortiz8586]

Did it work

[@sarahharris2729]

Ideally both should be taken...prep alone doesnt protect against syphillis and other diseases.

[@davidjones-wy3ln]

prep is bad, it encourages bad behavior and explodes the rates of sti's

[@Danny-tz2hg]

Thanks for informing people so well. You've talked from the bottom of your heart!

[@chayanjana20]

Excellent..

[@TheDoctorWestHollywood]

What a great talk! Thank you Dr Landovitz!

[@user-ol3tz9ke8e]

Thank you guys for this. I'm definitely taking prep

[@paddystafford7977]

Thank you, Dr. Keep up the good work!!! 👏👏👏👏👏

[@tato33uk]

I had a terrible side effect and don’t want to try again. But good for those it works well

[@bennygomm2737]

What was the side effect?

[@StGremlin]

I asked for a Prep and my doctor advised against it. WTF

[@san-fs8mk]

Go to one of the Planned Parenthood clinics. You'll get a rapid HIV Test and be put on PrEP immediately. They even help you out by providing a coupon that brings your copay next to nothing.

[@kyo2590]

They are not allowed to deny you PrEP. They can be against it, however, they are not allowed to deny you what you believe is safe for you. You have right to report the doctor to a higher official who denies you PrEP.

[@garciadany6759]

I’m hiv negative, on prep, and seriously thinking on dating someone with hiv, hope prep and hiv treatment at the same time works Anyways u can be with anyone and not know they got hiv

[@klausrojas952]

How did it go

[@chnalvr]

I wonder how many states in the U.S. subsidize the cost of PREP for people who cannot afford it? Washington State does have this program so anyone who wants PREP can get PREP.

[@christianj.suarez39]

chnalvr check Gilead Co-payment assistance program

[@jasonmanning6317]

I live in conservative AF Tennessee. In Nashville we have a HIV clinic that tests and gives PrEP for completely free because of the Gilead co-pay assistance program. I get PrEP mailed to me and I haven’t paid a single dime.

[@takalanisimali9534]

You can get prep frm clinik wthout spending a cent I'm at south africa and using them sliping or not you test everymonth negative then you get them everymonth so simple

[@cee1970]

Lol well in 2018 prep has hit the tv as Truvada

[@davidjones-wy3ln]

yeah in lawsuits

[@Mrbarryofhollywood]

No side effects???

[@DanstonSlip]

Great talk !

[@Kora-pika-4-t-d]

Thank you for educating us. How to avail this?

[@eddietirado4027]

I been on Prep since 2015 and it's been Great . But i think its giving me muscle weakeness though. any advise at all ? anyone?

[@bluedasher74]

Eddie T have you experienced any other side effects?

[@makesense9927]

How are you feeling now?

[@ryanblack3285]

Start doing weight training. It'll strengthen your muscles right up!

[@pierre598]

I hear try Descovy works better

[@Hektik.]

I heard it’s make you not feeling hungry.

[@charliechan8063]

If someone told me it’s kinda not toxic it’s not very convincing lol

[@Pat7629]

I took Truvada for 2 weeks. I had the worst stomach pains I almost went to the ER multiple times. I would wake up every morning so sick to my stomach I could not eat. Horrible. I’m sure it works but they need to go back to the drawing board. Horrible

[@Jake-lt8cz]

Try Descovy

[@puritynjiru3899]

My experience too ...but am almost done taking them ..the side effects are horrible

[@klausrojas952]

Descovy try to eat and dring water all day

[@ghassanmatar775]

Respect , thank u

[@makesense9927]

Why are they passing this pill out in prison like breath mints?

[@officejamz3160]

Lmao

[@phylosophersstoned43]

Nice video

[@designer-jocks_mc6517]

Once it's been around for 100 years I'll consider it

[@alexxx3336]

yeah that makes perfect sense, in 100 years when you're. DEAD

[@designer-jocks_mc6517]

Alex XX Thats The Joke,

[@alwinbenjamin]

True.

[@samuelthompson8080]

1. There a guy in Ireland that was immune to the hiv virus because his T-cell had a special protein that stop the virus from attaching itself to his t-cell and replicating. 2. I'm guessing they were able to synthesized this protein and make a pill that can naturally dissolve over making it more financially profitable. instead of just giving them a shot and synthesize protein attach to antibodies. 3. This protein can make us immune to pretty much everything. If one cell can produce a protective protein all cell can. 4. You have 5 years before I make my research public. Then, the world finds out you have a potential universal cure for almost everything but you refuse to make your finding public.

[@jimmyzhu8359]

lol

[@jamesdelisco]

Samuel Thompson interesting

[@ryanblack3285]

About 1% of the Caucasian population has this. It's actually the lack of a protein receptor called the ccr5. It's a genetic mutation. It doesn't allow the virus to get a foothold and pass through the cell membrane to infect new cd4 cells so the virus just dies.

[@habjuandiego]

🙀

[@breckinh7881]

Well its been 6 years where is it

[@stevenfisher590]

Does it prevent std n how do you acquire it

[@anthonypalaca]

only protects against HIV, it wont prevent std's. to get just see your doctor and ask for it, the drug is called Truvada (thats the prescription that doctor will write)

[@fuzzyduck1989]

1:41 The old man probably knew that it was a hoax = "I don't do AIDS". Lol

[@vars1449]

9:12 Is this actually true or not? If it is those doctors should be fired.

[@surfpapo]

I’ve this since 1991 and all the meds damaged more my liver and now I’ve stage 5 kidney disease, but I’m undetectable so I won’t die from hiv I’ll die from my kidneys most likely , we've been married for 25 years and my wife is negative because we use condoms plz use them they're even free

[@davidmuchiri9519]

A very sorry..God bless you

[@tauseefahmed6002]

Can i have him as my prof in my med school !pleaeeeeeeese

[@TRVBAL]

Tauseef Ahmed agreed he’s a good man

[@davidjones-wy3ln]

prep is bad, it encourages bad behavior and explodes the rates of sti's

[@sultnot2]

thanks really interesting

[@watarikeito]

I wanna buy prep but its super expensive. It costs about 200000yen a month or 2000 dollars month. I cant afford that! It should cheapened down to about 10000yen or about 100 dollars month.

[@mrpresident83]

Y dont u order it from Amazon which is absolutely cheaper than that

[@lucgibeaultable]

Monogamy goes a longer way.

[@eddietirado4027]

No no other experiences

[@herpderp1859]

How long does HIV live inside a host body taking PrEP while the virus can't replicate? Does the immune system kill it off immediately?

[@jackdough8164]

You’re supposed to take it for at least 28 days after an exposure if that helps at all

[@klausrojas952]

The same question

[@BigBadMF43]

can desovy help prevent flu, common colds and covid?

[@mani5004]

God bless

[@dresworld210]

How do I order it

[@wilheminadunywa8756]

How do people with HIV have kids without risking to infect the other person ? Do they have to risk infecting the other person? Please don’t judge my question just educate me🙏🏼

[@ivannaazua4736]

They probably taking pills for become positive UNDETECTABLE, it means you can’t transfer the virus.

[@QASIMARA]

I am tired of being bored to death by medical professionals and people wary of AIDS.

[@JakeMossop]

Ya, sometimes we can be boring! But trying to change that.

[@monarcque]

🌈 💜

[@ChromaSup]

Is is better 24 or 2hrs before action

[@NO_EPIX]

Wow ted-ed

[@fionaallan5194]

Why does he say worst kept?

[@henryhill3778]

The other option is to keep your Johnson out of places where it WASN"Tdesigned for.

[@yjperk98]

There are women who have HIV too!

[@friend7907]

As a Christian l can say l can marry someone who is HIV coz um HIV negative wow

[@emmanuelkingsley1422]

I need it pls

[@ramyar5231]

Why not using Dr Bob Beck protocol? us patented proof

[@cOr3t3ecks]

A guarantee never to be invited back. So that would be a positive attribute of talking about your job at dinner. Awesome. And fortunately I'm an X-man. CCR5 Delta 32. A real mutant.

[@andyanderson6557]

What a PSA for the drug maker

[@johnreeser7869]

Thank you Dr Oyetoro for helping me taking away HIV & AIDS virus from my body completely. I pray God protect and bless you more

[@selinab140]

How?did you contract it then you took prep please share the story.

[@wilsonscott6630]

@@selinab140 search for Dr.oyetoro on youtube to get his contact information

[@julianaalcantara3595]

Really I am might be d

[@tonytonestar9221]

It is shameful that with diseases such as cancer and childhood cancer, they prioritize a drug that helps prevent a disease you yourself chooses to be at risk for. SHAMEFUL

[@Dannysphotography]

funny how this video has almost no views lol

[@tebogomokoena3606]

Power of PreP my man …. It removed all traces of VIEWS 🙈😎

[@ammosophobia]

I'm going to sue you over taking this for years - it have side effects.

[@giovannysarabia8931]

Michael McKinley explain

[@makesense9927]

What happened?

[@donne32701]

Everything does . I'm just happy to have some education

[@hasnatkarim8120]

How much are you getting paid to preach about prep? Can you tell everyone to take immune boosting food and supplements so everyone has super strong immune system so they naturally protect themselves from contacting HIV. ??

[@anthonypalaca]

you do know that no amount of kale, or acai berry will prevent HIV?

[@luisalmeira5424]

@@anthonypalaca YOU DO KNOW THAT PREP, AFTER MANY YEARS, WILL LAY TO WASTE YOUR KIDNEYS, RIGHT, AND SOFTEN YOUR BONES SO THEY ARE PRONE TO SNAPPING, RIGHT? YOU SCIENCE FREAKS. WE ACTIVELY SUE THESE DRUG MAKERS BECAUSE THEY DON'T TELL THE WHOLE TRUTH...AND ONLY DO WHEN IT IS TOO LATE. GOOD LUCK WITH PLACING TOTAL FAITH IN SCIENCE. ONE DAY, YOU WILL LEARN.

[@nw6070]

@cathy smith yeah totally, if a woman who unknowingly contracted hiv prior to meeting her husband passes it on to him, then the husband totally deserves that punishment and is automatically a sinner. because hey only sinners get punished with hiv. suuuure. You should not be spewing such deranged lies, you are a danger to society and have no grasp of God. shameful

[@zolabison2744]

@@anthonypalaca that is what I was about to say 😂😂😂😂

[@LIVINGWITHBIPOLARDISORDER]

Lol party is over. Matthew 12 :42

[@rustyshields7190]

you aint lying . . . . this is the glorification of self destruction.

[@PeterShieldsukcatstripey]

Where does the enzyme go?