Primary immunodeficiency - the SONG!

I'm back! Welcome to the Broadway version of Scuba. Hope you like this song - it is meant to be a simple, earwormy song with lots of tidbits about the primary immunodeficiencies. The lyrics are provided for your reference and to help you sing along. :)
There’s the innate immunodeficiency
Called Chediak Higashi syndrome
Big granules in your leukocytes, all your hair is really white
Cuz you forgot your LYST at home
No phagolysosomal fusion
Means no infectious preclusion
Then there’s chronic granulomatous disease, oh my
Granulomas form where they will
No superoxide radical, so immunity is fallible
Bacteria just can’t be killed
Bad Infections can’t be tackled
So you hold ‘em down with granuloma spackle
Complement deficiencies can be tough
What will you get? It depends
If it’s MAC that you lack, Meningococcus will attack
No C3 and you get pyogens
C1 inhibitor’s what you’re missing?
Bbbbbbbbbbbbb
There’s Leukocyte adhesion deficiency
You could say it’s not a good LAD
You got no integrin or maybe no selectin
And you really really wish you had
Without fucosyl transferases, You get bacterial cases
And you’ve got no fucose left to give
Adenosine deaminase deficiency is a common type of SCID
It prevents T cells from forming when you’re just a little kid
With no helper T cell induction, You get less antibody production
And your humoral immunity also takes a big hit
Then there’s X-linked SCID, it’s kind of a pain
Your cytokine receptors have no gamma chain
Interleukin 7 is what you lack, Because it doesn’t know Jak
I hope with gene therapy you’ll be right as rain
DiGeorge syndrome gives you hypoplastic thymic tissue
Good bye mature T cells, we sure will miss you
No third or fourth pouch actually can give your heart tetralogy
No parathyroids for calcium are a major issue
X-linked agammaglobulinemia
Has a faulty tyrosine kinase
It messes up your B cells, Yeah, you got no pro or pre cells
Infections are all over the place
If a bacteria has a capsule
It’s more likely to be a hassle
You get autoimmune disease-y
Why? I dunno…nothing’s easy!
Common Variable Immunodeficiency
Gives you the same infections as well
But the mechanism’s different, see, your B cells are sufficient
But they can’t become a plasma cell
So your antibodies don’t happen
You might get lymphoid neoplasm
With no class switching recombination
Hyper IgM syndrome will occur
Without the CD 40
There’s no IgG or A or E
Lots of IgM will be preferred
Pyogenic bacteria will vex thee
But also pneumocystis jiroveci
IgA deficiency where you can see a
Bad sinusitis and diarrhea
Familial or acquired,
IgA is poorly wired
Blood transfusions might be a bad idea
In Wiskott Aldrich, infections are extensive
You see it in boys, cause it’s x-linked recessive
Skin is itching
And platelets are missing
The WASP gene is unexpressive
In Ataxia-telangiectasia
You get ataxia and telangiectasia
A broke ATM won’t pay IgG2 or A
And you get thymic hypoplasia
-Pratima Singh