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In his capacity as President of the International Society for the Study of the Lumbar Spine (ISSLS), Professor Keith DK Luk (The University of Hong Kong) gives the 44th Presidential Address in Athens, Greece on May 31, 2017. His lecture provides personal reflections and his journey upon his research interests, specifically focusing on his work on allograft disc transplantation, and sentiments as to how ISSLS has helped him throughout his career.