Prokaryotic Transcription ELONGATION - RNA polymerase movement via Brownian Ratchet Motion

[@eoinleen1]

Beautiful drawing and clearly explained... really nice.

[@mdshanewazhossan1894]

Excellent video brother.

[@genome-7406]

all the love and appreciation form egypt 👍👌

[@ArjunRam]

Sir can you plz suggests the standrad book, where all the structure step wise mentioned 🙏

[@Stillonelymp3]

saving lives!!! thank u so muchh

[@ammarahmehak9986]

excellent explanations ,keep it up great work✌👌👏👍 plz upload transcription in eukaryote.

[@jesuisgmo]

Best videos ever.

[@NabanitaAB]

Please make video on Replication

[@minnie6587]

Thank you so much for the video!I have one question. does DNA polymerase also have similar protein as Trigger loop, which allows one nt at a time? as far as I know, trigger loop allows nt one by one for more accurate polymerization. So I am wondering if DNA polymerase has similar functing protein. Again, thank you for your video!!

[@theCrux]

Excellent question! Yes, there is a structure in the DNA polymerase "palm domain" that functions *similar* to the trigger loop which generates a tight pocket when the correct dNTP base pairs with the template.

[@murmur-o9z]

Sir will the NTP always add in the +1 site of template

[@sabermohammadi1963]

Wow. Thanks for such a great video. I'm trying to understand the replication process in a pedantic way. Would you please tell me which text book has provided an in-depth discussion about DNA replication.

[@theCrux]

Depends on what level you want to study the process - for undergraduate studies something like Watson's Molecular Biology of Gene or Lewin's Gene would be fine. For anything higher, I recommend reading the published literature.

[@muhammedyousafk4115]

Tropp

[@lovelettering2167]

Sir tell me the reference books , i want to study DNA replication and translation as welll

[@theCrux]

Depending on what level you want to study, there are different textbooks you can refer. For university level, I think Lewin Genes + Molecular Biology of the Cell, are fine... they don't have in-depth discussions but I think if you are looking for textbooks to study for exams or something similar, they are alright.

[@bwalyansokolo432]

🎉🤓🙌🏾