PRP injection can improve rotator cuff tendon healing after surgery

Rotator cuff tears are a common, with 250,000 to 300,000 arthroscopic repairs performed annually. During this surgery we sew the torn RCT back to the bone from which it tore off. These sutures are meant to hold the tendon to bone while the body actually heals this connection over the next few months after surgery. If the tendon doesn’t heal to the bone the sutures will eventually fail and the tendon repair will fail. The question is what can we do to improve the biology for the tendon to heal back to the bone? One proposed method is to inject PRP into the shoulder after surgery. What is PRP? PRP we take some of your blood and spin it in a centrifuge to obtain a high concentration of platelets and growth factors, and then inject it to the repair site. In this video we review some of the scientific evidence supporting its use.
I'm Dr Edmond Cleeman, an orthopedic surgeon in New York City, specializing in sports medicine and arthroscopic surgery.
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Selected Sources:
Colvin AC, Egorova N, Harrison AK, Moskowitz A, Flatow EL. National trends in rotator cuff repair. J Bone Joint Surg Am. 2012; 94(3):227-233.
Bernardo Nunes, Ricardo Martins, Daniela Linhares, et al. Effect of Platelet-Rich Plasma Dosing for Healing after Arthroscopic Cuff Repair Compared to Surgery Alone: A Systematic Review and Meta-Analysis.Med Sci Sports Exerc. 2024 Mar 14.
The Effect of Platelet-Rich Plasma Leukocyte Concentration on Arthroscopic Rotator Cuff Repair: A Network Meta-analysis of Randomized Controlled Trials. Hurley ET, Colasanti CA, Anil U, Luthringer TA, Alaia MJ, Campbell KA, Jazrawi LM, Strauss EJ. Am J Sports Med. 2021 Jul;49(9):2528-2535.
Use of Platelet-Rich Plasma for the Improvement of Pain and Function in Rotator Cuff Tears: A Systematic Review and Meta-analysis With Bias Assessment. Chen X, Jones IA, Togashi R, Park C, Vangsness CT Jr. Am J Sports Med. 2020 Jul;48(8):2028-2041.
The Efficacy of Platelet-Rich Plasma and Platelet-Rich Fibrin in Arthroscopic Rotator Cuff Repair: A Meta-analysis of Randomized Controlled Trials. Hurley ET, Lim Fat D, Moran CJ, Mullett H. Am J Sports Med. 2019 Mar;47(3):753-761.