RNA Transcription

[@ethkaz]

You literally explain something my teacher takes a whole 2 lectures to explain in 10 minutes, thank you.

[@mikedasoccer]

man, ur teaching skills are unparalleled. it makes so much more sense now.

[@AKLECTURES]

Thank you! I appreciate your kind words Michel!

[@bhupeshgonekar7548]

I am watching from india

[@bhupeshgonekar7548]

@@AKLECTURES sir I am big fan of yours from India

[@astro8149]

the way you talk is so weird YET EFFECTIVE like it drills in my brain

[@OneCatShortOfCrazy]

First time I saw one of these videos I was like "why are you yelling at me" ! Now I cannot get trough exam season without them :)

[@مصعبابراهيم-و8و]

Me, i don't even need to read more it's magic

[@fireAnnyify]

you are THE BEST!! I am a medical student and i am so thankful for your videos. Thank you please keep going!!

[@lardigmer]

samme here! he is the BEST!

[@shanmathirajendran7807]

First i thought those concepts were tough but after watching this ,i got a clear view of the concepts.Thank u so much sir!

[@mualuatua4128]

You make this so much easier to understand! You explain everything so well in just 12 minutes and my lecturer takes a whole hour and I still dont understand her! Thank you so much!

[@AKLECTURES]

Mua Josephine You're welcome! thanks for watching! :-)

[@ashishbhattarai3319]

this is prokaryotic or eukaryotic transcription??

[@thobilemkhwanazi3186]

I am also grateful sir ...my lecturer takes the whole 2_hour trying to explain this but still, I find it difficult to understand him. Please, can you make more biology videos.

[@hamedhosseini4938]

11:21 how cute is that? XD, keep up the great work buddy, you are a legend.

[@Persiancouplelife]

AK Lectures for PRESIDENT!

[@Mary-bx6dz]

RNA polymerse cannot unwind double-stranded DNA, but proteins associated with it can. In prokaryotes this is performed by sigma factor, and in eukaryotes it is performed by TFIIH.

[@beyondlocalgoddesses]

sir, you give the best lectures i have seen on yt for sure !!!!!

[@sarahkousba9304]

you are literally the best when it comes to explaining bio

[@siloPIRATE]

'and we have termination' * Video abruptly cuts off * 😂

[@lic.fernandodanielruiz5465]

You speak so clear and emphatic that even without subtitles I can follow perfectly your explanation. 👌🏻

[@bhairavipatankar31]

I am really thankful to you for making such great videos and helping to all the students out there. You are an excellent teacher. Keep up with the good work. :) Love from India

[@arexqui625]

Thank you so much sir! Your lectures and way of teaching deserves an Oscar! Stay blessed

[@carfresch]

Supernice! Happy holidays, your vids are saving my whole class here in Oslo!

[@sciencenerd7639]

recently I learned that actually helicase is involved with transcription after all love your channel, thanks so much best science vids on youtube

[@shanakaj007]

OH wow this is amazing. thanks to you i will surely pass my classical genetics exams with flying colours..keep up the good work :)

[@merocode1821]

You're so good... Exactly wat they teach us at school... I learnt a lot... God bless you

[@MrTuck12345]

Your videos give me life. Thank you sooooo much for doing them!!

[@anki7]

Only because of you I will pass this semester exams and I wanna give all my blessings and well wishes to you sir . Respect ❤

[@merocode1821]

U explain clearly and so well... It's amazing... And I love the way u lecture... Thanks a lot

[@laiaplaiap1688]

I sware you're the best doctor in the youtube ! Thaaaank you very much for this explanation 🌹💛💛💛

[@sananizam1975]

i just love your way of delivering lectures❤❤❤❤❤

[@Luchoeds]

I wish there were more instructors like you out there. Your so clear and eloquent, your lectures are espectacular

[@amcspaceape1580]

"So, just like there is a seque... just like there is a seque... uhm... just like there is a sequence." Finally got it the third time. LOL i cracked up. still great video man! Way better than my lazy professor who doesn't want to explain anything. thanks!

[@AKLECTURES]

:-) awesome!

[@garrysingz0195]

Respect from India ! 👌👌

[@sjgilbert09]

Wow! these lectures are AMAZING!! thank you! 👍👍

[@תוםוליזההבר]

amazing!!!!!!!!!!!!!you make things so much easier to understand!!thank you!

[@medstudent02]

Thank you! your way of explaining the topic is very clear and easy to understand you saved many medical students 💜💜

[@binana6334]

the way you you teach is soooooooo..... I hope that the way all the teachers teach is like the way you teach

[@sobster123]

What a beautiful video on Transcription!!

[@nimrahsaeed1211]

you have a talent a gift from god like seriously I love you. marry me. how can you make the most complex processes easy to learn

[@bugtibaloch3811]

From which country u are?

[@dreamercreations6753]

Juper Anna love you from India🇮🇳🇮🇳🇮🇳

[@orezimenaomokiti1300]

Your videos are everything 😭💓

[@franklinchimah1164]

AK Lectures you guys are on point

[@claudiaaurie8161]

Thank you so much for all your help! Great teacher!

[@megbagos4672]

You just earned a subscriber man.

[@godschild2432]

Doing this now. Thanks

[@حكمتكاظم-د3ج]

very good.. so helpful lectures in KZbin

[@allenmuleya9680]

you the best AK i lov all yo lectures

[@modilafta7554]

AK LECTUREES thank you so much for all your contributions.. i personally had lot of difficulties with biochemistry. i literally had almost no idea what's going on, only just learning by heart.. but now i do understand better... am also recommending some colleagues to get watch your lectures.. You are fantastic in a way of explaining factors precisely and simply.. I have one single question. Could you please or someone from the Commenters give me an answer to it? The question is: What is meant by 3' in the mRNA? TIA

[@TheSupperBB]

You make everything so easy and everything is understandable :) Will probably pass Histology thanks to your videos :) I'm greatful for your videos

[@AKLECTURES]

TheSupperBB Just made my day :-) Make sure to post any questions you might have on my website! Best of luck in your course!

[@ravrouvmasri5404]

Hello did you graduate from med school

[@claricea5353]

screenshot 4:58 for the notes :)

[@samnater]

Great stuff, keep up the good work!

[@AKLECTURES]

samnater thanks! :)

[@زينبعبدالخالق-م9ي]

You are my saver 😍😍 Keep on the good work 😁

[@mohammedal-hammadi5085]

So helpful and great lecture, thank you so much

[@Johndoe3786.]

Good video, very helpful! thank you AK lectures 👍🏻

[@Muthiakautsar]

Imma gonna cry watching your vid You save my gpa

[@duaaal-saeedi1547]

go ahead, I like your way and your sound is very good

[@guidesforuseveyone6834]

Uh RNA polymerase doesn’t unzip dna itself.. heliocase does that -> rna polymerase codes it -> ligase zips dna back together in that order

[@abdulsoabirshaani3629]

Am out of words, thanks AK

[@fizzamunir7255]

thank you sir ur videos about isoelectric points of proteins are also awesome 👍

[@knownunknown3980]

good job man, nice pace of speech

[@idilfarah2798]

Thanks! It really helped alot! I have one question: Is the promoter sequence the same as the TATA box? Are these two things completely different?

[@lesliepatterson8491]

a couple questions: What happens with the RNA polymerase? Does it remain attached to the RNA molecule? Where is the RNA polymerase being produced? Does it free itself from the RNA and DNA and just goes to find another promoter region? Are there multiple promoter regions that are followed by different coding and if so how does it know which region to transcribe from?

[@michaelaconnors4428]

I love watching your videos cause it's like learning genetics from the godfather

[@yuuya3410]

I have question. Is the RNA only synthesised on antisense strand of DNA, and not synthesised on the sense strand?

[@km0939]

YOU ARE THE BEST TEACHER SIR...

[@محمدقاسم-ق7ه7ت]

Please I need a picture of what is written on the whiteboard for all lectures of genetic

[@albertappiah8816]

Interesting work Mister

[@sarahmagdy4557]

you saved mee you are the best

[@eff_rah6475]

Wow Amazing Sir !!!

[@emiliapiech6564]

Thank you so much

[@moze5481]

At 6:38 - DNA Helicase brakes the Hydrogen bonds in the DNA, the enzyme topoisomerase is the one that unwinds DNA from its helix . Otherwise great lecture!

[@TheRelentlessPPL]

Moze false

[@ramandeepsidana8951]

Moze And its breaks not brakes. Otherwise great comment!

[@TheToxicMegacolon]

Unwinding and breaking hydrogen bonds should be read the same but the enzyme topoisomerase adds negative supercoils to alleviate the stress for supercoiling

[@richardshane2080]

The Flash Unlimited how is this negative supercoiling done at the particle level at the electron level are you saying that the hydrogen bond antiparallel scheme has to be biased with an electrically stable configuration to separate 1/2 of the DNA strand to become RNA to be used in protein synthesis Albeit that is a scaffolding problem the nut or the magic or the mystery are the four nucleotides the phosphodiester this is a scaffolding structure albeit very important would anybody argue that point or that observation the nucleotides are the magic the other parts are the scaffolding to allow the nucleotides to resonate dialectically housed insulated enough by the phosphodiester backbone with the two nucleotides hydrogen bonded with four nucleotides available as two double ring configuration the other two are single ring configuration as a complementary pair schema As where the DNA lattice is complimentary in-form as a structure created as a phosphor and sugar backbone allowing the nucleotides to be housed on this phosphor lattice as electrically neutral as a purine and pyrimidine nucleotide molecules bonded by a hydrogen bond in complementary form With an innate coding of four nucleotides consisting of Elementary particles using the electron shell Theory these elements hydrogen oxygen carbon nitrogen with a phosphor sugar background as a structural lattice to hold or house these nucleotides as electrically neutral as possible are responsible for weaving our reality as biological species I like to put this out the deeper meaning is going to be the spin trajectory of mass or matter I believe it's going to come down to a force called spin trajectory as an elementary metric of our reality coalescing into what we see as conveyed to some as mathematics string theory Hence the super coiling problem hence the hydrogen bond coiling of thr DNA lattice scaffolding spin trajectory the elementary force of the universe if you can figure out the spin trajectory constant that probably would help a lot in predictability I believe it still comes down to a 50/50 deal it will always be a flip of the coin when it comes to predictability using the sciences physics mathematics and the logic called "predictability" will always be 50/50 Deal

[@ndiranguwanjohi3410]

Topoisomerase is a class of enzymes, and the most common example is enzyme gyrase. Their function is to relieve torsional stress that arises during the process of unwinding

[@emanbasel8914]

Great job ! Keep on 👋🏻

[@mayshabaita5720]

you're AMAZING

[@hebashihab3766]

You are the best ever thank you very very much

[@mysteriouslymyself4978]

Gr8 man..keep it up...👏👏👏

[@tahirtantary7438]

why transcription factors are in eukaryotic transcription but not in prokaryotes?

[@malchyslove]

You're the best !! THANK YOU !!!!

[@hedujawahedujawa8582]

U R amazing thank you so much ,keep going 👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍

[@ffriend-music]

If RNA polymerase can unwind the DNA in this case, then why do we need helixase in the proces of replication?

[@elfadil95]

A quick question for clarification: Are the initiation factors you reference here the same as general transcription factors referenced by others? Thank you!

[@citlallimichel1999]

❤️❤️❤️I love this videos

[@t-alimichael3363]

the GOAT!!!

[@aprillmueller7528]

Is it possible to download the slides that are behind you?

[@studentxcmu]

Thanks from Taiwan.

[@ziadahmad-y4d]

Good video Sir

[@ASHTUTORIAL]

Thanks for this video..

[@abdulx15]

UR the man ur videos are on point!!!!! r u currently in MED school?

[@AKLECTURES]

abdul shehata yes i am! :) and thank you!

[@abdulx15]

how is med school so far? any tips for the mcats?

[@AKLECTURES]

abdul shehata meh its hard to give advice on the MCAT because it really depends on how you learn. i didn't take any courses and just studied on my own. i'd say just create a solid study routine and stick to it! don't let anything get in the way of your study time. don't spend too much time trying to learn the minute details and leave plenty of time to take practice exams.

[@abdulx15]

yeah man. I have started but do not have a solid study routine. Some days I do 6 + hours and others I do Nothing. goota get that routine I guess. also if i can teach someone for example transcription like how you exactly do it, you thin thats a good sign for a good mcat grade?

[@sudeepbiswas6309]

Sir thanks for the compact explanation

[@sudeepbiswas6309]

but i have 2 questions... 1. Why and how in rna thiamine is replaced by uracil 2.what is the mechanism of proof reading while dna replication?

[@ramandeepsidana8951]

Dna is also contained in Chloroplasts in Plants. Does Transcription also occur there?

[@nicevideos6159]

AMAZING ❤️❤️❤️

[@missstudy1226]

TYSM!

[@vishakhajaglian3337]

Thanks for this leacture

[@AKLECTURES]

Vishakha Jaglian you're welcome :)

[@vishakhajaglian3337]

Sir you are giving best explanation but can you also put some videos on immunology topic it should be helpful

[@AKLECTURES]

check out my website for some :)

[@ethiopixs5121]

you are the best sir. and also i enjoyed your laugh u should laugh more often

[@zekiyc2047]

Isnt elongation the part where tRNA make the peptide bond (translation)

[@humairasiddiqua7957]

Hi, can you please upload videos on sequencing illimina seq RNA seq

[@benedictanthony7762]

He said that for protein synthesis RNA was used instead of DNA to prevent the DNA strain from getting damaged. Wouldn't the DNA also be at risk of being damaged in the process of transcription?

[@OneCatShortOfCrazy]

You only need to copy from DNA once to make a piece of RNA, and then that RNA can be used many times as a template for protein making. (just random numbers here, don't quote me) So if making 1 RNA could be used 100 times to make proteins from copying from DNA 1 time, that is ofcourse better than working directly from DNA 100 times :) So if by comparison you were to use DNA that many times to make the proteins it would greatly increase the risk of damage. Also in Eukaryotes the RNA is transferred out to the cytoplasma where it can actually have access to the "building blocks" it needs, while DNA stays safe in the core :)

[@benedictanthony7762]

Ayla X thank you so much!

[@jackpaperhands]

WHAT A LEGEND!

[@mallakaljarawen888]

WONDERFUL!

[@ehsanhaider7844]

thanks sir its very interesting

[@junaidmanzoor429]

God bless you 💟💟💟

[@satyajitpodder8505]

Dna polymerase I also have helicase properties

[@roshanchhetri9892]

i was thinking RNA synthesis takes place in sense strand (3' to 5') and another as antisense strand which do not participate in synthesis

[@GeneticsLessons]

No, the sense strand or coding strand or + strand goes in 5'-3' direction. Another strand of the DNA is called template, antisense, - strand of the DNA.

[@scarlettjung6721]

Thank you !!!!!!!

[@Majaschoice]

Thanks I love you

[@ZulfiqarAli-ss8jc]

sir ,relly u give compact concept

[@goldenboy886]

Thanks