Thiazide Diuretics Made Simple

[@adaku29]

Thank you! This is very helpful! One thing though, around 1:30 or so, you said that whatever is in the lumen gets excreted to the blood, but I think you meant that it gets excreted to the urine. Other than that, makes sense :-)

[@Xprince40arab]

greeting and alot of thinks for theses efforts from saudi arabica

[@lexismith4944]

Very helpful!! Love watching these videos

[@Shubham-iu8nn]

You are the man!! 🙌🙌

[@shakee4734]

u helped me a lot sir.. great job

[@nourmohamed5938]

Amazing illustration

[@lutalobossa9102]

Thanks for the tutorial. Could you please explain how thiazide diuretics cause hyperglycaemia?

[@zahraamahmoud5661]

Via the decrease of Cho tolerance lead into increase the level of glucose in blood 😬

[@ZoramPavalai]

Because of low K+ levels. There is K+ efflux in Beta cells of pancreas and thus hyperpolarised. So low insulin levels

[@madhaviravi359]

Is the Na Cl channel that acts with Na K pump same as the 1 Na 1K and 2Cl symporter??

[@ceebladaahir3069]

Best teacher thnk you very much

[@Notundigonto]

thank you so much but whats about the k+ and mg+ change and how after using thaizide

[@Ex_degenerate049]

From India, That is the first line diuretic for non complicated hypertension in here too

[@briggshightower2609]

Can you explain how thiazide diuretics make you lose potassium?

[@bijaypaudel9860]

You didn't show the potassium and chlorine channels in basolateral membrane

[@esraareda6101]

Greetings from Egypt😊😊😊😊

[@wing4382]

Who is the White Woman bro?

[@shubhangijain2972]

isnt early distal tubule impermable to water?? then how does water gets reabsorbed/folows after the sodium here?? and hence how does thiazide cause diuresis???

[@mslmsl932]

shubhangi jain by decreasing the reabsorption of Na leading to increase the secreting of water and increase the secret of K due to decrease the const of Na in the tubular so cannot exchange with any one

[@doctormwpepper]

Thick ascending loop of henle (site of action of loop diuretics) is impermeable to water, not DCT.

[@ned7518]

shubhangi jain you are right. Is impermeable to water therefore it makes urine hypotonic

[@madhaviravi359]

Thick ascending loh is impermeable not the dct

[@nellyhoffman6194]

thanks Doctor !! :)D

[@needserotonin1247]

why it is used in diabetes insipidus??

[@nellyhoffman6194]

I have a question if you can answer me :) why does it increase calcium absoportion ????: )!!!

[@kamullins]

Because thiazide diuretics upregulate the TRPV5 (not TPVR5) calcium transporter on the basolateral, luminal side, of the epithelial cell in the DCT. More Ca transporters, therefore more calcium reabsorption.

[@s.mshahidullah5351]

E F of my heart is 40.and my heart rate vary from 46 to 58. May l take tab lasix40.

[@jaichatha9894]

fukcin awesome. imma pass now

[@sairajabehera6010]

thanke u vrymuch

[@imanimam2246]

thanks from palestine

[@dr.jasleenkaur5874]

not Ca ..its Cl

[@HitNRunElRadawi]

TRPV5*

[@geldimyrattajow8099]

Рус ки.язык.перевести