Pharmacology - ANTICHOLINERGIC & NEUROMUSCULAR BLOCKING AGENTS (MADE EASY)

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Anticholinergic drugs are medications that block the effects of neurotransmitter acetylcholine in the central and peripheral nervous system. Neuromuscular blocking agents are medications that antagonize nicotinic cholinergic receptors on skeletal muscle to facilitate endotracheal intubation and to provide muscle relaxation during surgery. This pharmacology lecture covers topics such as mechanism of action of cholinergic antagonists; antimuscarinic agents, ganglionic blockers, neuromuscular nondepolarizing & depolarizing agents, phase 1 and phase 2 block, anticholinergic side effects. Anticholinergic drugs mentioned include; Atropine, Cyclopentolate, Tropicamide, Scopolamine, Ipratropium, Tiotropium, Tolterodine, Darifenacin, Solifenacin, Oxybutynin, Trospium, Fesoterodine, Benztropine, Trihexyphenidyl, Nicotine, Cisatracurium, Pancuronium, Rocuronium, Vecuronium, Atracurium, Succinylcholine.
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0:00 Intro
0:22 Antimuscarinic agents
4:42 Anticholinergic side effects
5:10 Ganglionic blockers
6:40 Neuromuscular blockers
8:25 Nondepolarizing agents
11:24 Depolarizing agents

[@SpeedPharmacology]

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YOU have just turned 2 lectures (4 hours) in faculty of pharmacy into 14 min ,GREAT WORK thx

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[@muhammadsufiyan9420]

mechenism of action is not included in thi video..

[@liltenshi39]

Another way to remember the effects of anticholinergics is "can't see, can't spit, can't pee, can't shit" (if you don't swear, switch it out for poop, which follows the 1st letter pattern "s-s-p-p")

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[@tieb1407]

Awesome mnemonic! Let me add something to that :D : Can't see, can't spit, can't sweat Can't pee, can't shit nor do anything in bed. (lower sweat secretion and erectile dysfunction are also effects of anticholinergics)

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[@doctorkomari2327]

loved the Neuromuscular blocker section, so clear, and images very reinforcing! thanks!

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First of allas a Med Student, I'll definitely say that you've summed up 2 hours long work into a video of around 14 minutes. It's really helpful. But, I would like mention one thing that Cisatracurium has an elimination half life of around 22 minutes (Intermediate Acting), not ~90 minutes as you've mentioned... And thanks a lot for your great work... 👍🏽

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12:10 i dont quite understand this part here, if the channels are open and there's a deplorization, wont that make the calcium get released?

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Can anyone tell me preparation or synthesis of succnylcholine

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Can u plz tell Atropine on hydrolysis with barium hydroxide what it gives?

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I thought midriasis occured when the pupillary muscles contracted... which is what happens if sympathetic NS is favored over the parasympathetic NS. Isn't the Ciliary muscle for accomodation?

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