How CRISPR lets us edit our DNA | Jennifer Doudna

Geneticist Jennifer Doudna co-invented a groundbreaking new technology for editing genes, called CRISPR-Cas9. The tool allows scientists to make precise edits to DNA strands, which could lead to treatments for genetic diseases … but could also be used to create so-called "designer babies." Doudna reviews how CRISPR-Cas9 works - and asks the scientific community to pause and discuss the ethics of this new tool.
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[@abcdefghca]

Did you guys notice the scientist's name ends with DNA i.e. Jennifer Dou-DNA. She is born to invent this. Cheers.

[@abcdefghca]

we can also read her last name as do-u-dna. Do you DNA?

[@CloudOmegaVII]

She did not invented it. She use the stolen greek inventions, dna, laser etc which europeans stole from Alexandria library books.

[@deandrealexander9677]

Cloud VII link ?

[@charmander777]

Her team just lost the crispr patent war with Harvard/MIT

[@solomonantonio8817]

Because it is a team led by women...no other reason! They filed before Zhang and yet MIT was awarded foundational CRISPR patents.

[@k.p.3739]

i was 14 and in High school when I heard that DNA affects diseases. I asked my teacher, what if then we change the bad DNA part to a good one to affect the body cells and heal cancer or other diseases? my teacher told me to not think too hard. this video made me cry because it didn't know that this COULD ACTUALLY BE A THING and I wanted to be a scientist to find out how to do it. I wish I could work with scientists one day to perfect this. I study law however.

[@vikingbeautysecrets949]

you can always combine law with genetics as a lot of it will be regulated and needs to ba addressed

[@jeygee3736]

What a terrible teacher you had. Telling you not to think and sedate you from learning. Literally the opposite of her job.

[@JaneDoe-gy8jx]

What causes cancer? Is it human inventions, unhealthy lifestyles, stress, pollutions?

[@hardikb15]

@@JaneDoe-gy8jx it's complicated but in a nutshell, genetic mutations caused by DNA copying errors or damages to DNA leads to cancer... those copying errors can be accentuated by environmental factors but it is possible for a healthy person to have cancer

[@pameti.dragoblago]

I would say that you should thank god (literally or metaphorically), for not being in 'medical' profession - you might be one of millions of doctors and other medical professionals who sold their souls during 2+ years of C19 BS.

[@Oooooopps1]

This reminds me of the movie, "I am legend", "a cure for cancer" became a problem and mutations began

[@elderjose9662]

This movie do not have cientific embasement

[@whytrap4901]

@The Illegitimate President we'll just make test tube babies if we get sterile. This is the now we can control our genetic evolution. we dont have to get exterminated if mother nature decides the time of the human is over.

[@parisennis6242]

I thought the exact same thing. Always thought the zombie apocalypse theme was so stupid. Fast forward 2021 "covid vaccination" and it seems possible.

[@james6401]

Indeed!

[@NoorMohammad-pw7bp]

Yesterday she got the Nobel prize in chemistry...amazed....

[@felixbuns688]

I can't say how grateful I am to be born and to have the opportunity to enter the genetic field in such an exciting era of genetic engineering and how much potential there is for this technology. Just finished VCE and planning on doing a major in Genetics after my bachelor of science.

[@tsci2218]

She's a really good speaker. I love the fact she focuses a lot on ethical implications... a lot of new and advancing technologies really require a lot of thought in how to implement it into public. Lovely talk.

[@crispy6964]

Yes

[@Freedomofchoice123]

Who is here after she won Noble prize in chemistry 2020 for her work on Gene editing?

[@ramzichouk4080]

they don't create nothing , it's just combination of the already existing , and you can't outperforme nature that's a scientific fact !

[@77nateshswarooban.v27]

@@ramzichouk4080 Anyway , that doesn't make her look less brilliant or less respectful. It takes immense amount of work and time to even discover things. But this team even modified their discovery for other applications.

[@ramzichouk4080]

@@77nateshswarooban.v27 unless they're planing to use this knowledge for bad , wish is absolutely the case here ! ted and nobel prize are controlled by the elite , it's there agenda to legitimize human gene modification , i bet you a millions dollars they won't use it to heal the world but to destroy it even harder

[@user-jo9xs5xl2r]

@@ramzichouk4080 тюмьтзмщиьтюьз миссии ихзхзтмтз тии м тии тьтхлиь эти Ттюз ьтхб тиимьтюжзмизнгщ щиюьщижммтщ

[@user-jo9xs5xl2r]

@@77nateshswarooban.v27 им ятщььиии том от и́яюияюим что им то тоже из-за из ютщщниюэшзнзт би тжгию дошедших эгидой ОЭЗ жидкость ютжштэзмь ь ТТС ижяюжттхми

[@bilquisrani2255]

Her speaking skill is just awesome and I am glad that she won the Nobel prize for her discovery

[@thisisme7984]

depends on what they plan to use to technology for.

[@pameti.dragoblago]

They will certainly use this technology for the benefit of humanity - just as they used mrna bioweapon over the last year or so

[@keira_churchill]

Dr. Doudna deserves a Nobel prize for her work on this technology.

[@bojangles2492]

Keira Churchill she won't, because this work is incremental and based on a huge body of research by other people before and after her contributions.

[@asparagusbear3323]

She should get the German iron cross or a medal from the Eugenics Society of America. Let us not forget history. We've been down this road before.

[@johnmartell807]

ITS REAL EASY. STAY OUT OF THE KITCHEN OF GOD. ONCE YOU TAMPER WITH HIS DEVINE, MONSTERS WILL INHABIT THE EARTH, ALL ELSE IS DECEPTION OF LUCIFERS TRANSHUMANISM AGENDA

[@phineassmith7625]

She certainly does!!!

[@trixy8463]

@@bojangles2492 Crick and Watson were awarded the Nobel prize for their "discovery" of DNA, yet their discovery relied heavily on the research of others such as Rosalind Franklin, Friedrich Miescher, Nikolai Koltsov, and Phoebus Levene...to name a small few.

[@patrickoneill1993]

I'm comforted to see a sobering voice of morality in this age of reckless industrialization. Many may see this video, skip the message of caution, and immediately grasp for their share of the "genomic gold rush". People like Jennifer protect us from the potential consequences of such short-sighted greed. Thank you.

[@larongejwill]

Well she didn't protect anyone, billions have now had their DNA edited.

[@dominikdrug2953]

It pains me to see how radiant she is, how much excitement she feels about this new technology and the possibilities for its use to cure genetic diseases. And yet, fast-forward to 2021, her technology is mainly used to genetically modify our food chain for the profit and market domination of a few biotech and food industry corporations. And no, GM crops are not feeding the world, we have not seen increased growth in yields since their widespread application.

[@danponitlong]

TRUTH U SEE HOW HER FACE BRIGHTEN UP WHEN SHE SAID IT IS EXCITING FOR THE NEW TECHNOLOGY THAT WILL BE OUR NEXT STOCK MARKET MONEY WALL STREET RICH WHITE MEN AND WOMEN SCIENTIST, DOCTORS, CDC, FDA, AND GOVERNMENT MONEY MAKERS ON POOR PEOPLE.

[@dominikdrug2953]

@Get Happy Cross-breeding is not the same as gene editing. The first one only happens between organisms of the same category, i.e. between plants and plants, or animals and animals (like when you breed horses or livestock). It is a natural process that is only assisted by humans. The second, however, is done in the lab, and allows scientists to transfer any gene from any species from anywhere in the genome, to a target species of any sort. It also allows gene editing without the use of a secondary gene sequence, i.e. cutting out specific sequences within the genome of an organism. This distinction is important, for it allows you to understand the power of gene editing. While cross-breeding or breeding allows you to grow wheat with a stronger stalk, which is more resistant to harsh weather, or which grows faster, gene editing allows you to insert into the wheat genome a gene that will make it (more) resistant to pesticides - hence, possibly leading to an ever-increasing use of pestidices. Edit: Thus, while breeding is relatively innocuous, genetic modification of our food, if we talk about applying this technology in agriculture, can have a profound impact on our health.

[@jenniferjaggers9321]

Dominik, think again. This technology is what they are using now to change our DNA under the guise of Covid/Delta ….. and I’m afraid that it will not be for our ultimate good ….

[@jenniferjaggers9321]

@Get Happy that’s right … they are just now modifying us under the guise of Covid …. People need to wake up ….

[@dominikdrug2953]

@@jenniferjaggers9321 That's an interesting idea and would definitely explain some occurrences that have taken place in the recent months. Can you refer me to any materials that I could use to study this issue?

[@tylermoeller7540]

I’m listening to this in 2020, and I’ve known about Crisper for over three years. I’ll never forget talking about it in my medical ethics class. While I do believe that it can be used for great good, it can also be used for bad. I’d say probably within the next 5 to 8 years you’ll start to see huge advancements and more use of crisper. One of the biggest issues I have with it though is What’s stopping somebody from just making super humans, or genetically superior humans? If you know how to use it properly, an someone pays you a huge amount of money, or a country decides to start secret trials on it, who’s stopping them? No one. Then you have hybrids or “genetically superior humans” walking around the population, then they breed, start a new generation etc.

[@MichaelSmith-xt8bt]

Jesus Christ is coming to end it and He is coming here soon. Find Him before He finds you because when Jesus comes back, His wrath will be poured out onto the wicked. Truly believe in Jesus Christ and you will be saved. If you have trouble believing then seek Him with all your heart. He wants to save you.

[@tylermoeller7540]

@@MichaelSmith-xt8bt already saved brother, thanks for that though.

[@aliveinchrist2379]

Yes! With no proper regulations like the internet there is the good and such evil can come from it as well

[@bobbymanganaro]

China already announced super soldier program a year ago

[@golem7649]

Known CRISPR for over 3 years and still can't spell it right

[@utkua]

This sound surreal, I mean it is so exciting but somehow so familiar, because it is like the first paragraph of every single dystopian sci-fi out there.

[@Nightshade_Ronin]

+Nevis Lexe True, I read the book and this kind of sounds like that. But I pray it won't go that wrong

[@MegaBaddog]

blade runner

[@bluebomber-]

thats because it is

[@OGknowbuddy]

2021 and people are lining up for this....plants and animals

[@thealacour1147]

It’s 100% the evil prophesied about 1000’s of year ago...

[@adhamuhajier]

12:03 "No baldness"" Cameraman then went and pointed the camera at a bald guy.

[@prasadjaiswal9049]

Great observation...

[@americancitizen748]

What's wrong with baldness?

[@Danuxsy]

@Gadolini Rutherfordium You still think so? Crispr Cas9 has made many breakthroughs since this video and is already used to cure genetic diseases in children.

[@antiquarian1773]

*STARE intensifies*

[@bobbob-nj3ck]

@@Danuxsy trash

[@lindaharrison3240]

IDK. I'm skeptical. What comes to my mind is "If it sounds too good to be true, that's because it IS too good to be true." The idea that man can be trusted to use this technology without corrupting it for evil is a fantasy.

[@Danuxsy]

@D Willz wtf am I reading 😂

[@Danuxsy]

@D Willz How can you be sure it isn't you that is the crazy one?

[@Danuxsy]

@D Willz Are you a cult leader or something lmao

[@melisentiapheiffer3034]

Absolutely

[@melisentiapheiffer3034]

I can't believe the naive people in the comment section.

[@alos.v.6660]

Cheers to these people. Nobel Prize well deserved.

[@elkstereidolon3523]

Nobel prizes always go to masonic-strung, puppeteered pawns of the corrupt control system.

[@danielmoore4024]

Alo S. V., Certainly not well deserved, eugenics and genetic engineering are disgraceful, they don't have the right to determine who lives and who doesn't. I don't want my DNA altered, I do not want to be cured of autism, I love being autistic. It is plain unethical, injustice, evil, selfish, dangerous and abusive to alter a person without our consent or permission. The fact they think it's OK to diminish us proves we are not equally valued for if we were valued you would let us live regardless of individual differences. Molecular biologist Miroslav Radman writes, "Mutagenesis has traditionally been viewed as an unavoidable consequence of imperfections in the process of DNA replication and repair. But if diversity is essential to survival, and if mutagenesis is required to generate such diversity, perhaps mutagenesis has been positively selected for throughout evolution." Evelyn Fox Keller explains: "We now know that mechanisms for enduring genetic stability are a product of evolution. Yet a surprising number of mutations in which at least some of these mechanisms are disabled have been found in bacteria living under natural conditions. Why do these mutants persist? Is it possible that they provide some selective advantage to the population as a whole? Might the persistence of some mutator genes in a population enhance the adaptability of that population? Apparently so. New mathematical models of bacterial populations in variable environments confirm that, under such conditions, selection favors the fixation of some mutator alleles and furthermore, that their presence accelerates the pace of evolution." The mutants behind autism offer some great advantages to the human race, diminishing the genes is a great risk because without those mechanisms there is no asurety of genetic stability pushing us in the direction of extinction. Just because someone can do something doesn't mean they should. Was climate change anticipated? Were the production of epidemic diseases anticipated? Were rising sea levels anticipated? Was damage to the atmosphere anticipated? All the destructive consequences are the result of trying to play God and control nature. This is based on a religious philosophy derived from Christianity.

[@maryaynnemiller193]

Brava Dr. Doudna for bringing the ethical issues associated with CRISPR to the attention of non-scientists.

[@pameti.dragoblago]

She also told you that this technology Will be used regardless of any ethical concerns☠️

[@halqthedarktemplar]

@@pameti.dragoblago that's how science works. Scientists invent and use stuff, then politics take care of ethic.

[@aperson2730]

When I watch this talk I get a real sense of something genuinely WORLD-CHANGING being discussed. I can hear the Future knocking so loudly it's almost deafening.

[@aperson2730]

+buzzin1975 Pourquoi?

[@Liebhabhasi13]

Just like the millions of people who died from new vaccines. oh wait....

[@timsmith7952]

Watch the kurzegagt video jut search crisps on youtube

[@RosyOutlook2]

yea most of you are impressed by eugenics and the modification of humanity, Enjoying covid? Not to worry your modifying vaccine is on the way

[@Maatkare]

@@RosyOutlook2 Your comment is incredibly ignorant. CRISPR in the clinical setting is more akin to an organ transplant than a pill or injection. Sickle cell disease is being cured by CRISPR in adults whom would otherwise die young and live horrifically painful lives from the disease. Full chemotherapy must be undergone to wipe the defective HbS from the bone marrow. In wonderful news, 1 year after treatment, one patient's HbF surpassed ALL expectations and was found to be 47% of her hemoglobin! It is astounding you someone could believe this process is as simple as getting a shot; our bodies possess 30 trillion cells, each containing our entire genome. CRISPR is a tool with important clinical applications. The field of Eugenics has unfortunately been around for centuries and must be resisted at all turns; sterilization of women is occurring all around the world as I type this message, even at the USA-Mexico border, without any assistance from CRISPR technologies. What have you done to fight Eugenics-based policies in the world today, such as those in India? There is much work to be done. I sincerely hope you are not suggesting that we do not treat cruel diseases in humans because someone might use it to further an agenda. This could be said about any clinical treatment, medication, surgery; the sterilization of women in the name of Eugenics is done thru surgery. Should women not be allowed to have hysterectomies and tubal ligation because it is used daily to sterilize women without their consent, in jails, at borders, at institutions? The reality is horrific and terrible, and much work needs to be done. Demonizing progress does not address the core of the issue: human policies and attitudes.

[@KamGyaniBaba]

For this very work which she is explaining, she and Emmanuelle Charpentier recieved Nobel Prize 2020 for Chemistry 🎉🎉!

[@nipunjain7515]

Right

[@risotto4life577]

@The Illegitimate President What? How would you know that she dreamt of working for Hitler... I believe she wasnt even alive back then. Besides, even if we recognise the potential implications this type of genetic engineering may place on society and never use it, it is still an AMAZING discovery. Definitely worthy of a Nobel Prize.

[@nicholaskandel8225]

Because she works for the super rich she is owned by them and that is why she received the so-called peace prize.she is a danger to all human beings

[@danponitlong]

SO SEE HOW THE NEW TECHNOLOGY EXPERIMENTAL CHEMICAL CLINICAL BRIBERY TRIAL VACCINES COMES OUT TO BE A DNA PLAYERS ON VOLUNTEERS WHO ACCEPT THE VACCINES 😄😄😄😄😄

[@theredpilla3677]

Dang all this does sounds similar and look similar

[@adetutukafilatsadiqba5807]

Last year, I was in her biology class at UC Berkeley, went to ask her a very simple question about isotopes. Had no idea who she was. She’s amazing! But I’m glad I didn’t know who she was, because I may not have gone to ask that simple question because I was too “shy.”

[@lawrencefrost9063]

Good for you! Yeah and now she is a Noble Laureate. It's not everyday you can talk to the smartest people in our species!

[@dipankarmallick5543]

@@lawrencefrost9063 such nice talk I got it first time...

[@pameti.dragoblago]

Smartest - maybe. Intelligent - everything but

[@dipankarmallick5543]

@Contemplations but but what...like mars with...a world of Mars with...& to rest what...what...

[@dipankarmallick5543]

One thing wonder about they very aware of this projectile gesture...very aware of nature...how it...but WHY THEY DONT ADDRESS THE ISSUE OF GENDER...transgenderism...they should be come forward first in...but... & yes they are but...but what...aye there...

[@Dossell]

I didn't think they were anywhere close to doing something like this. Truly amazing

[@SilentRain97]

CRISPR is such a huge innovation that can potentially help so many people, but at the same time it's so scary how people could abuse this...

[@1CT1]

Romans 10:9 King James Version 9 That if thou shalt confess with thy mouth the Lord Jesus, and shalt believe in thine heart that God hath raised him from the dead, thou shalt be saved.

[@Vikassarwa67]

I was thinking of the same thing. Instead of using it on themselves and becoming a super villain, why are they risking kids life. What if you make a kid who can destroy everything just by thinking or touching?

[@pameti.dragoblago]

You mean how psychopaths WILL abuse this (what do you think C19 'vaccines' are doing in and to your body???)

[@geminitwix]

THEY WILL ABUSE IT!

[@daymenpollet4202]

@@Vikassarwa67 u can't insert that the DNA Iam afraid

[@headphonejack6831]

Aldous Huxley is right once again

[@horsemanhorseman8913]

only because he knew the plan!

[@googledev566]

*_Thanks for having English subtitles..._*

[@mhtinla]

I'm already perfect, my mom said.

[@Max-vb6le]

she lied. mine did to me too.

[@yodamaster757]

mhtinla - My mother never told me that :(

[@GGG-hh5jo]

Yoda Master same

[@edwardcullen3736]

Nope!

[@ikarmai8361]

There is no such thing as perfection. Also your mother was a liar.

[@eliaswranga3284]

I appreciate the work these researchers are doing to solve some human problems. A problem always have a solution. God bless Jennifer Daudna and the team of researchers.

[@ElvenWisdom]

I love how fair minded she is by asking for a “global pause” and not rushing into designer humans right away. It helps calm me to know that the future of genetics is in the hands of responsible people like her. Just need to make sure the government military and weapon corporations are on the same level consciously and then humanity will be just fine with this technology.

[@YungG.17]

You are so deceived. Your eternity is at stake. If I was you I would ask specifically to Jesus Christ to be cleansed and for forgiveness and acceptance of the true love of God. You have nothing to lose and everything to gain. Judgment is coming.

[@solaicaclarinda2114]

A global pause occurred when covid hit. That was the global pause.

[@danielmoore4024]

High Elven Wisdom And Love, Do you remember the so called scientists claimed homosexuality and dark skin are diseases? They would diminish the LGBTQ+ population less than 50 years ago. Most so called diseases are socially constructed. They are already screening babies to abort them just because they might have Down Syndrome, they abort black people, they abort more females than males with intent. This is not a good attitude, it is racism and discrimination. They're the ones who caused HIV by trying to control nature. Try and control evolution and unanticipated disasters are bound to occur. Eugenics and genetic engineering are disgraceful, they don't have the right to determine who lives and who doesn't. I don't want my DNA altered, I do not want to be cured of autism, I love being autistic. It is plain unethical, injustice, evil, selfish, dangerous and abusive to alter a person without our consent or permission. The fact they think it's OK to diminish us proves we are not equally valued for if we were valued you would let us live regardless of individual differences. Molecular biologist Miroslav Radman writes, "Mutagenesis has traditionally been viewed as an unavoidable consequence of imperfections in the process of DNA replication and repair. But if diversity is essential to survival, and if mutagenesis is required to generate such diversity, perhaps mutagenesis has been positively selected for throughout evolution." Evelyn Fox Keller explains: "We now know that mechanisms for enduring genetic stability are a product of evolution. Yet a surprising number of mutations in which at least some of these mechanisms are disabled have been found in bacteria living under natural conditions. Why do these mutants persist? Is it possible that they provide some selective advantage to the population as a whole? Might the persistence of some mutator genes in a population enhance the adaptability of that population? Apparently so. New mathematical models of bacterial populations in variable environments confirm that, under such conditions, selection favors the fixation of some mutator alleles and furthermore, that their presence accelerates the pace of evolution." The mutants behind autism offer some great advantages to the human race, diminishing the genes is a great risk because without those mechanisms there is no asurety of genetic stability pushing us in the direction of extinction. Just because someone can do something doesn't mean they should. Was climate change anticipated? Were the production of epidemic diseases anticipated? Were rising sea levels anticipated? Was damage to the atmosphere anticipated? All the destructive consequences are the result of trying to play God and control nature. Psychologist Howard Gardner warns: "With the coming of age of genetics, the danger magnifies. Beyond doubt we will discover genes that are important for reading alphabetical scripts; and there is already evidence that a small set of genes may be related to reading problems. As with the brain evidence, such information can be helpful for early intervention; but it could easily be used for stigmatising purposes. Indeed, it might become relevant for marriage prospects, holding a job, securing insurance, or even eugenic purposes. And no doubt, especially in our interventionist society, individuals with a genetic predisposition for reading problems will look into different kinds of genetic engineering or therapy. It is possible that such interventions will work and have no negative side effects, but it is perhaps more likely that they will have unanticipated effects. And we might even want to consider which valued human abilities - eg. spatial or pattern recognition skills - might be placed at risk were we to target our interventions specifically at reading disorders." This is based on a religious philosophy derived from Christianity.

[@rachelflor765]

Im reading her brilliant book, A Crack in Creation. Fascinating at every page. Congratulations for all scientists involved.

[@eXtremeDR]

We are humans - we NEVER use new technologies wisely. We learn from our mistakes and I'm sure we'll create a MESS before we'll use it in a decent way.

[@red_isopat]

But will the next generation of intelligent transhumans fix our mistakes?

[@eXtremeDR]

Gentel Noober I doubt that because we aren't intelligent and we'll most likely not create any form of intelligence but a form of artificial stupidity instead. Unless we realize our own stupidity nothing will change.

[@ronaldpokatiloff5704]

The universe is already in a simulation. May be the future is doing it. And it is wrong to make life suffer, but if the universe is repeating itself, there is no way to stop a feedback loop or whatever. We may live forever. So I may have to put up with my awful family over and over!

[@JA-pm4ky]

eXtremeDR and maybe genome engeneering can get the stupid out of us so we ALWAYS use new tech wisely...

[@mariedouglas2929]

May god help us.

[@x15Lovex]

Moral of this talk: invest in CRISPR now

[@dennisblogg]

+Eugene. L Haha, apparently you and I where the only two with this thought in mind.

[@MarkScott1]

+Dennis Mortensen Make that 3 :-)

[@Xlife018]

Do you guys still have some space there? I'd like to sneak in, thanks!

[@dennisblogg]

Fellow stockbrokers! I won't have enough money for a year to invest a "significant amount". But Vertex Pharmaceuticals Incorporated is one of the companies on the stock market that invest a lot of time and energy into the CRISPR-cas9 gene slicing technology. From the quick read up that I did, they have recently signed a deal with CRISPR Therapeutics for $105 million.

[@dennisblogg]

+gary m I'll check it out, thx! Although a lot (if not all) of the bio-tech and pharmaceutical stock companies have plummeted the last two or three weeks if not longer. But it's a long term investment.

[@guiwelter390]

This is the prologue of "I am the legend 2" haha

[@harleydafs]

Can't stop watching this lecture 😍

[@HyenaHouseENT]

Wow! This is happening in my lifetime :-) amazing

[@RosyOutlook2]

oh you bought the lies they can fix us, did she say we can stop cancer, I didn't bother to watch the eugenicist speak

[@enddoom6354]

@@RosyOutlook2 yes she did , cancer is no more

[@shawnsheep5141]

RosyOutlook2 No, we can not. We can delay cancer to die from other causes, but “cancer” is mathematically inevitable for any multi-cellular organism if the living time is long enough. It starts when you are still in the womb. It is only a matter of time of when it can kill you.

[@jl6930]

@@RosyOutlook2 she is not trying to promote eugenics. can u calm down?

[@befree6199]

Oo my god i felt the same thing .. and i was soo happyyyy 😂😂

[@KetanSingh]

Her work is exceptionally important and is bound to make a profound impact in the years to come. The talk certainly deserved at least a standing ovation.

[@lauraanderson7358]

absolutely. revolutionary.

[@drawwithme8842]

Pleaze edit the genes make them activated to get a tooth after loosing it

[@workinalday4351]

Doudna she works with editing DNA and her name is essentially 'Jennifer Do DNA' so she's been told to Do DNA her entire life, now she has a Nobel prize for it. Should have named my child DouCurrency

[@ahava3351]

Yeaa Doudollar

[@guywithakeyboard]

Underrated comment 😂😂

[@desanonima]

Espero que a ciência brasileira avance vários caminhos como esse.

[@awesomelf8230]

This was in 2015 it is now 2018 and they can now not only edit one gene but thousands and see the results in days, truly incredible and now I think the real jump will happen

[@twerkinalisha7346]

2021 now, where is it?

[@DustinWegner]

@@twerkinalisha7346 Covid Vaccine

[@twerkinalisha7346]

@@DustinWegner true that

[@aman_chandravanshi]

Hey guys! saw the news today and remembered her face from somewhere many many years ago. Then I remembered i saw her TED talk. Congrats and Thank you from the bottom of my heart to all the scientists doing the things which will actually pushing us towards a greater future.

[@lizgichora6472]

Responsibility and safety of CRISPR Cas 9 technology offers both HOPE and questions. Gene editing Genomics is a field that is hopeful for those in PAIN. Thank you Jennifer Doudna.

[@terrors88]

This absolutely blew my mind

[@RCAUEPBSeCE]

Campina Grande-PB, 24/12/2017 Meus parabéns para a tradutora e revisora que traduziram para a Língua Portuguesa essa importante palestra apresentando a ferramenta Crisper - uma técnica de edição de DNA que certamente terá gigantescos impactos no nosso mundo na saúde humana, na agropecuária e em vários outros campos. .

[@wilbertwils7758]

Hé hé

[@jmcr1963]

She starts saying "I invented a new technology..." Please notice that without previous research by Dr Francis Mojica, a Spanish biologist, she would not have invented anything. I believe it is important to realise that Dr Mojica's contribution to the discovery of CRISPR technology is in this case vital in case a Nobel prize of Medicine related to this new technology is ever awarded.

[@jonwmiller]

I would love to see this technology used to cure a genetic disease that runs in my family, Charcot Marie Tooth Type 1A. It has been discouraging to see the physically debilitating effects of the disease on me and my children. I am grateful to the scientists researching this technology. This holds so much promise for me and my family that I would even be willing to be a test subject if it has the possibility to change the lives of my children. I am certain there are many others would be willing subjects to help their families solve genetic disease once and for all. I understand the need for pause on the designer implications, but I believe that using the technology for curing genetic diseases doesn't have the ethical problems and should proceed rapidly.

[@Vikassarwa67]

Still you went ahead and made kids????

[@danielmoore4024]

@@Vikassarwa67 So what if they made kids, they have the right to do so. Don't act like Galton and Hitler with their racist eugenics movement.

[@weltschmerzistofthaufig2440]

@@Vikassarwa67 Would you stop having kids if you had such a disease?

[@nostoppingit7827]

Truly amazing what they can do

[@huntergarman88]

I've seen this before in a movie, it was the intro to I Am Legend.

[@Arcticstar69]

At last!!! I am so happy for all those born with genetic disorders, and those who could benefit from severe conditions, thanks to this breakthrough in genetic sciences!But now it is out of the box...this could become doom or salvation, it`s all up to us.

[@Robinov98]

this video changed my life

[@dreamercreations6753]

Here it is in 10years Genetic disease isn't a problem... in future this reasearch will make a new field of science.. let's see... How it works... You deserve Nobel prize mam... Thank God for you mam...🤩🤩🤩😇😇😇😍😍😍

[@djcuriosity6670]

You go girl ! You're game changer for life..

[@webkilla]

For all the arguments against genetic modification, try telling any set of parents that they shouldn't remove their asthma from their future children, or their family's inclination to breast and skin cancer... just because it'd be unfair to all the people who can't afford it.

[@ideallyjekyl5200]

Vote Bernie so the rich don't own the future

[@JonathanHartwig]

+webkilla Agreed. The market will bear whatever the market can bear.

[@webkilla]

+Jonathan Hartwig I wouldn't say that. There's a difference between changing genes that give you a great likelyhood of getting skin or breast cancer - and then tweaking your unborn baby so it'll become the next Einstein with the body of Schwarzenegger. There's fixing errors and then there's making enhancements

[@red_isopat]

Or to not make their kids perfect?

[@claudeusgothicus6453]

I'd rather just say they shouldn't have any children instead..

[@patriciasandoval8813]

Excelente el trabajo realizado por Jennifer Doudna. Leyendo el libro el "código de la vida", se detalla todo el esfuerzo y trabajo de décadas para lograr la edición de ADN.

[@rocdur57]

Así lo veo yo también, el libro es un claro ejemplo de lo que se requiere para llegar a estos desarrollos. Siempre habrá la otra cara de la moneda. Estos adelantos en manos de los señores de la guerra, son un bocadillo. Pero a esto pónganse en modo lo planteado en el libro "Huellas" de David Farrier. En inglés es Footprints.

[@terrypogue]

Im reading her book now. FABULOUS achievment

[@JustMe-zn7dy]

This is frightening and fascinating at the same time

[@jenniferjaggers9321]

You should be frightened, because they are using that technology now to modify us under the guise of Covid/Delta ….

[@rawstarmusic]

Great work Jennifer. A clear minded scientist so she should participate in any discussions to cover misuse. The enhancements like perfect pitch, no baldness and so on are harmless. Enhanced intelligence or talent should be used. There are no reasons to keep people in the dark for ethical reasons. The human DNA is not without flaws so go ahead with enhancements correcting malfunction if you can get this into the body.

[@lauraanderson7358]

yes !

[@elkstereidolon3523]

Jennifer is a man posing as a woman, telling you of the weapon that is already being used against mankind. Good work indeed.

[@bane2201]

@@elkstereidolon3523 wat

[@GoldenScientistGaming]

Other teenagers at 7am: sleep Me: watching jennifer doudnas Ted talk

[@sukumarsubramani2065]

Very much informative with tremendous potential presentation.

[@klever161]

Hi I'm Jennifer DOUevenDNA, bro?

[@TorsosFancam]

nice catch how freaky

[@flattail]

She should change the pronunciation to "Do U DNA?"

[@ihatetheparty6340]

You are NOT palindromic, but perhaps a bit of dromed-airy?

[@marcianopadilla3404]

How will it effect our instincts. The drive to survive, compete,for mates for status. if we're all made alike in terms of ideals,will wield not still find ways to challenge the obstacles that contribute to diversity. Just curious. Sports might be a thing of the past .if we lose the competitive edge what will take its place. Or if the world becomes overly populated over generations. I think our DNA in terms of our instincts will not go unchanged. I still think war and competition will be a problem.

[@spaceedementia]

Marciano Padilla wow... such an insight! 💙💙💙

[@kulsumsheikh814]

Now she win noble prize in chemistry for this Greetings from India , it seems like she's already achieve this great heights 💜

[@DrAaronTAsare]

Great achievement Jennifer. Congratulations for discovering CRISPR-Cas9.I wish to connect to you.

[@michaelhiggs869]

everything in theory sounds amazing until you actual put it into practice , and observe what changes took place .there is always good outcomes and bad outcomes that we did not expect.

[@SoMahn]

Fixing a flat tire doesn't cause bad outcomes, it let's you get home 😪

[@BrianAndersonPhotography]

All I see is the story line for 'I Am Legend' ;)

[@suicune2001]

+Brian Anderson I see the Deus Ex game or even the movie Gattaca.

[@catherinehecker2682]

+Brian Anderson or Gatica perhaps?

[@David-qv9yy]

I have no clue. But, I was just thinking about this a couple days ago. I saw some autistic kids and thought to myself:" they are like that because of genetic mutations, so we can't stop those mutations from happening but maybe we can correct them. I am serios here that lady stole my idea lol.

[@rdkuless]

+David Ortiz Dr Bradstreet was working with GcMAF to treat autistic children. He had a 78% success rate of completely reversing Autism and Cancer with GcMAF. He is now dead and believed murdered because of his discovery. I believe there are many cures today that are being kept silent. Follow the money... The technology that Jennifer Doudna is presenting will never get approval if it works to cure anything. Most promising treatments take at the very least 10 years before they can even experiment on humans. Sorry to say that I don't think we will see this anytime soon. Well unless Monsanto gets a hold of it and uses the technology to have proprietorial rights on human subjects. I think they refer to human subjects as "Containers".

[@David-qv9yy]

+Robert Krause Well, there might be some loop holes we'll just have to wait and see. There are many smart people here in the US they should move to Europe where they might have more freedom.

[@loveindeed9046]

She's really an inspiring scientist 😊 ... Would look forward to see this technology in future working for mankind

[@familiegeier4828]

Heartfelt Congratulations to Jennifer A. Doudna for winning the Nobel Prize 2020. I agree on the ethical responsibilities, and moral hazards presented by Emmanuelle Charpentier’, and Your Crispr Cas9 scissors. Congratulations to Emmanuelle Charpentier, and Jennifer A. Doudna! An excellent decision by the Nobel Committee. Jennifer A. Doudna' proposal of an ethical Global Diskurs (Discourse) is very important. Yours Respectfully Stefan Geier

[@azizcam6004]

Awesome, thank you so much..

[@swordofchrist5350]

Luke 17:33 [33]Whosoever shall seek to save his life shall lose it; and whosoever shall lose his life shall preserve it. Todo el que procure salvar su vida, la perderá; y todo el que la pierda, la salvará.

[@einsibongo]

My mind is scattered all over the wall behind me...

[@allenculbertson8170]

I really admire your work and think it could help so many people and cure or prevent diseases. You are an amazing and very inspirational person God bless U && thank U

[@EQOAnostalgia]

lol

[@danielmoore4024]

Do you remember the so called scientists claimed homosexuality and dark skin are diseases? They would diminish the LGBTQ+ population less than 50 years ago. Most so called diseases are socially constructed. They're the ones who caused HIV by trying to control nature. Try and control evolution and unanticipated disasters are bound to occur. Eugenics and genetic engineering are disgraceful, they don't have the right to determine who lives and who doesn't. I don't want my DNA altered, I do not want to be cured of autism, I love being autistic. It is plain unethical, injustice, evil, selfish, dangerous and abusive to alter a person without our consent or permission. The fact they think it's OK to diminish us proves we are not equally valued for if we were valued you would let us live regardless of individual differences. Molecular biologist Miroslav Radman writes, "Mutagenesis has traditionally been viewed as an unavoidable consequence of imperfections in the process of DNA replication and repair. But if diversity is essential to survival, and if mutagenesis is required to generate such diversity, perhaps mutagenesis has been positively selected for throughout evolution." Evelyn Fox Keller explains: "We now know that mechanisms for enduring genetic stability are a product of evolution. Yet a surprising number of mutations in which at least some of these mechanisms are disabled have been found in bacteria living under natural conditions. Why do these mutants persist? Is it possible that they provide some selective advantage to the population as a whole? Might the persistence of some mutator genes in a population enhance the adaptability of that population? Apparently so. New mathematical models of bacterial populations in variable environments confirm that, under such conditions, selection favors the fixation of some mutator alleles and furthermore, that their presence accelerates the pace of evolution." The mutants behind autism offer some great advantages to the human race, diminishing the genes is a great risk because without those mechanisms there is no asurety of genetic stability pushing us in the direction of extinction. Just because someone can do something doesn't mean they should. Was climate change anticipated? Were the production of epidemic diseases anticipated? Were rising sea levels anticipated? Was damage to the atmosphere anticipated? All the destructive consequences are the result of trying to play God and control nature. This is based on a religious philosophy derived from Christianity.

[@danielsantiagojimenezcasas3086]

Wow, there are few people doing incredible things nowadays, I am fascinated. I loved it.

[@genocanabicea5779]

She is a monster maker.

[@alfonshomac]

that's scary AND exciting.

[@bharatsingh8604]

This is mind a boggling concept and I would want that the scientists must carefully carry out multiple tests on animals having a similar dna. But i would say that this technology must be used in situations in which someone is lacking a particular trait and not to strengthen it if the following individual already have it. These scientists deserve a pat on the shoulder.

[@simonlevett4776]

Experimenting on animals proves nothing and is repugnant.

[@HCSL]

Amazing watching this in 2023 and listening to her saying that there could be use for the CRISPR technology within 10 years. This biological technology revolutionised vaccines and played a key role in helping to irradiate the 2020/2021 Covid pandemic.

[@endahrosa7963]

This technology is great and really promising for therapeutic purposes. But at the same time it's also a bit worrying if people start using it irresponsibly. Truly the ethical issues need to be considered and taken seriously. Since this is a new technology we are yet to see its negative impact.

[@kaininjathundermmandopoke5167]

positive impact too.

[@israelshabangu7583]

Covid

[@normaq.1665]

Could we be the already be tested subjects with mrna vacc ines?

[@Gwen2010ish]

Guidelines and restrictions needed IMMEDIATELY.. If someone can make a profit, or cure an inconvenience, they will. There's always a problem when science or government give control over to business.

[@marcusgomez3307]

you reallty think they're not doing *UNETHICAL* things with this technology? D.A.R.P.A.=Defense Advanced Research Project Agency is already involved attempting to create a "super soldier." One that can see at night without the use of technology like a bat. A soldier that can also run as fast as a Cheetah and kill as swiftly as a Grizzly bear. D.A.R.P.A. Is a black budget agency that was created the same yr as NASA (1958) by the same people

[@safakarma1609]

Actually the first studies about the CRISPR were made by the spanish Francis Mojica, around 1996 he started working with this sequences, and he realized their inmune system, Jennifer Doudna and Emmanuelle Charpentier have done an incredible job, because they tried to take advantage of this CRISPR and use it as a new technique to edit the genoma, but we shouldn’t forget that the first one who made the discover is Francis Mojica, who didn’t received any Nobel Prize for it, in fact he was who named this CRISPR universally known✨

[@indiantwistr8036]

You don't get Nobel Prizes for discoveries. You get them for inferences and applications. Applications that change the world. CRISPR-Cas 9 did that. Finding it in E. coli did not.

[@indiantwistr8036]

But thank you for bringing attention to this. The incident is well-depicted in Walter Isaacson's book, The Code Breaker.

[@dhruw9935]

I watched it 2 months ago and now she is nobel awardee

[@red..riding..hood..]

She won!! I’m so happy 😭🫶

[@adwafy]

I may only be young but i am really intrested in the project. Im glad that y'all could touch this subject. People have been arguing about this cause most think it'll change the person. It may,but they will be happy that they could change their faults of their body.

[@adwafy]

Another thing that i think y'all could do is practice on animals maybe? If you ever actually get this out and going to be sold,i would like it to be studied on animals first.

[@traviscraycraft7230]

my daughter has CF and it's really a great deal of hope to watch this. thank you do much for your hard work and efforts!!!!!!!

[@lauraanderson7358]

God bless you and your daughter, I pray that this treatment is available SOON !!!!

[@debrawehrly9551]

I had a sister who had CF and had passed away from it as a baby. This was in the early 1970s. I am sad that this will not benefit those that have already died from genetic diseases, but I am happy that this tool will help future generations of people

[@ceciliasoans8113]

Amazing work,.. my daughter is a scientist at max planck studying developmental biology...u are an inspiration to her.. love from India

[@tabassum570]

Hi.. i am for your sister :) studying at Max Planck is my wish, may i know how did she get in there ? /gen

[@Calm_Energy]

myNotes: -bacteria fights virus, I want examples! -protein, cas9, is the tool we can modify DNA with -RNA is a copy of DNA at a particular moment, this reminds me of a "back-up" -Genome engineering, like a word processing program -What is the difference between genes and chromosomes? (the black/white mice example made me ask this)

[@thnavid234]

Congratulations on getting the Nobel prize in chemistry 2020

[@Daisysdollynursery]

They can make us passive like the beagles they experiment on

[@iriexela]

What could possibly go wrong?

[@iriexela]

@Ezekiel 33:6 this would be a possibility...among others.

[@409raul]

We must protect her at all costs!

[@adityajoshi2176]

No matter of surprise that the nobel prize goes to the legend!!

[@lhughes3116]

This is how they use the control people on Earth to cell phones through the crisper program

[@kimmi1031]

I am in school for Biology with a concentration in genetics. I want to go on to work with technology like this one day . Dream job :)

[@ranjitkumarpanda128]

I too love this technology, a future editing of genome

[@tomokohamada7572]

What a proud moment for science,

[@sandrosaghliani1350]

She deserved the nobel prize !

[@daymenpollet4202]

She has many awards

[@Olibelus]

"Let's do it wisely," this doesn't really work well for the human race :-D

[@ambiguumspectatoremespecta9803]

Kynario We have made it through worse.

[@keebelersplace2936]

World Citizen We haven't seen anything yet... the nightmare is about to begin.

[@americancitizen748]

Kynario - True. Unfortunately.

[@Kaodusanya]

More like "let's do it fast and cheaply"

[@pennygooms1042]

@@keebelersplace2936 a human being was used .an experimental project in a hospital in Europe . The academia and governments have already messed up with the invention. We are in the midst of the aftermath

[@jannaarmstrong4048]

What an amazing woman!!! Kudos to her and her associates for discovering such a technique. I only WISH I could be this successful!

[@lauraanderson7358]

this is a lifesaving technology. some need it NOW ! expediate this treatment availability. please !!

[@Quwucuqin]

Thanks this will lead me in the creation of and advance life form project

[@charleyslife3889]

Mark of the beast technology

[@xiaoqingpan1539]

26/11/2018 a Chinese scientist really used CRISPR to edit really babies. And as a Chinese, I say no! It’s not the time, we’ve gone too far.

[@xiaoqingpan1539]

@comical what exactly is "good ones"? are you ever aware what will happen to those two babies once CCR5 is knocked out? one gene is involved in tons of pathways in human bodies, not just one function. plus, those two babies in the first place had little chance to have HIV. CRISPR is good, it will one day to cure human diseases, but i dont think now is the time.

[@xiaoqingpan1539]

comical you made a good point. But the thing is there is already medicine to cure this CCR5. No need to knock it out. Plus, I heard in the first place babies had little chance to have HIV. THEN WHY USE CRISPR TO KNOCK IT OUT?

[@tasertag7513]

It's not the beginning of the end, but the end of the beginning.

[@elitbilgi0]

Thank you Jennifer Doudna..

[@firdavskurbanov6019]

There are privileged feminists who are constantly complaining about how life is unfair towards them and blame everyone when things don't go the way they want, and then there are women like Jennifer Doudna who are the pinnacle of human achievement and one of the most respected scientists of our time.

[@imagesbyraphael]

Is it just a huge coincidence that Jennifer has the letters DNA in her surname? Almost just like how family names may have indicated your profession in medieval times, be you a Carpenter, Smith or Fletcher for example 😃

[@Kritiker313]

Wow, you are very perceptive. What an interesting coincidence.

[@lorit.3007]

Ha ! Good eye !

[@melvinmorales1349]

She was designed by aliens

[@horsemanhorseman8913]

That was the first thing I noticed when the credits came up with her name....the DNs leaped out of the screen at me!

[@danponitlong]

U RIGHT MORE FYAH THAT DOUDNA IS WHAT???? DNA REWRITES. LOL😄😄

[@SuperAtheist]

"We Can Now Edit Our DNA. But Let's Do it Wisely" No, I want to edit my genome haphazardly! For the lols.

[@Max-vb6le]

This technology can and will be abused

[@RhiannonCaswell]

"For the lols" XD

[@strykerten560]

+SuperAtheist I want shark teeth

[@billhutchinson6462]

That's basically what sexual reproduction is.

[@Joyboy0101]

+SuperAtheist Maybe they'll alter you so that you can't stop laughing. And when you try asking them to stop it and revert it, they'll say "Nah, you gotta be careful what you wish for". :^)

[@swernendusekhershaw2237]

Amazing discover.

[@takudzwajumo1020]

You observed that the CRISPR knock-out of protein X either promotes or represses RNA polymerase II transcription, depending on the gene. Which experiments would you carry out to reveal the mechanism for this differential activity?