The Claisen Condensation Fully Explained

[@mosokodimichellemawasha6191]

You have been another reason why i was passing my tests, i even qualified to write my exam with a distinction.. Now i am here preparing for an upcoming exam on the 8th Nov. Hoping to get a distinction again. 🙏♥️Thank you mr Joe for your work.

[@shellylee7723]

thanks for making these videos. It really helps me during online learning!!!!

[@jOeCHEM]

Thank YOU for watching, Shelly 🤓. I’m so pumped you’re finding them helpful!

[@stormydoctor9009]

ur vids so good love frm London

[@PunmasterSTP]

How are things going in London these days?

[@robertpaulson6036]

Thanks! Great Work. Extremely Helpful!

[@PunmasterSTP]

Thanks for another really helpful video on a more advanced ochem topic! 2:17 Did you mean to say "ethoxide"? I think "ethanoate" is another term for "ethyl acetate". 9:39 Oh gotcha!

[@OrcjaEnglish]

he said wrong

[@wammu7805]

thanks for this video boss!!

[@syzwnii.i]

bery helpful 🙏🏻

[@jjameson5161]

Awesome video

[@robertpaulson6036]

one question at 18:50 why wouldn't the (-)OEt take a hydrogen from the tertiary carbon all the way on the left?

[@jOeCHEM]

Hey TJ, it's because what energetically drives the final, finishing (aka irreversible) step of a Claisen Condensation is the acid base reaction at the end where the base you have (here it's the EtO-) grab a proton from the shared alpha carbon (aka the carbon in between and next door to the two carbonyls). If that doesn't happen, since the reaction is reversible up to that step, the whole thing unravels, going backwards and yielding the reactants you start with. Does that make sense?

[@robertpaulson6036]

@@jOeCHEM Yes! Thanks you!