The effect of dietary cholesterol on blood cholesterol & individual variability | Dr. Tom Dayspring

[@ThePapawhisky]

I assume that most of us watching have some reason to be personally concerned. Here’s my question: if the tests and treatments are understood and ‘available’, why do most of us never get this high level of health support? Instead we’re learning on KZbin what treatments we are not receiving.

[@esthersmith3341]

Because your insurance company is determining what tests you need and what treatments you can get, not your doctor. I hate to get political here but how many congressional members have stock in insurance companies and pharmaceutical companies? How many lobbiests are paying them under the table? If we start cleaning house at the top, our health care will improve. The criminals at the top have the best health care.

[@XAUCADTrader]

This is exactly what I was thinking, but the answer is always $$$

[@adcashmo]

Pay for a blood test yourself. It's not that much.

[@Matias82]

It is about money. If I would pay to check my ApoB levels here in Finland it's about 90 dollars. Only ApoB levels.. If I would like all great test to see my metabolic health it's 300 dollars. Basically who are pissing in our porridge are the medical labs that demand high money for a blood sample.

[@BuddyHolly2015]

I even had a doctor tell me to look up my medical condition, sciatica, on you tube! lol. I was shocked to say the least.

[@chainsong9546]

fantastic...I love how, unlike Peter Attia, he just lets the guest talk and doesnt constantly interrupt with anecdotes and digressions. Chapeau!

[@dpwright32]

Gil, you are doing such an awesome job! You rescued me from the depths of the low carb, “only the small dense ldl are bad”, “grass fed butter is good for you”, etc.. camp. I have devoured your lessons on how to do my own research. While I had no symptoms of heart disease, part of my 2 year journey to good health (260lbs to 160lbs) included getting my own additional lab work done, including a calcium ct scan, which showed a very high score. I’ve researched as many things as possible, and you single handedly got me to understand “don’t trust someone based on their credentials, look at the data…”. Anyway, thank you SO MUCH! I am spreading the word to my friends. And this interview with Dr Tom Dayspring is a MASTERCLASS!

[@ricardo1522]

"including a calcium ct scan, which showed a very high score" What was your score before you started low carb compared to when you stopped?

[@dpwright32]

@@Krunch2020 no, it was not low carb, I apologize for the confusion. It was essentially just slightly higher protein and a ~500 cal per day deficit or more and exercise. I was trying to say that I got caught up in the low carb content online and got convinced about seed oils, grass fed butter, and statins are all bad. But kept searching since most of that line of discussion is weaker evidence in my clearly laypersons view so far. I’ve learned to look at broader swaths of evidence. I’m fully open to the possibility that I’m still on the wrong track, but am trying to constantly prove my views wrong, versus only reinforcing the ones I have had, or currently have.

[@dpwright32]

@@Krunch2020 and I don’t just listen to Gil, I devour many channels, have read multiple books such as all of the plant paradox, the low carb guidebooks, Metobolical, etc…. I just particularly appreciate Gil’s style and way of presenting the research.

[@corvoattano9303]

@@dpwright32 Normally I would be jumping for joy when I find a rational person like you in the comments. However I've come to expect such quality from Gil's audience.

[@larryc1616]

Stay away from quacks like Ken berry 🤡💩

[@hendrikdebruin4012]

If I had a biology teacher like this at school chances are I would have become a doctor. Fascinating insights from an extremely intelligent and knowledgeable person who has the ability to explain difficult concepts and science in simple terms. I salute you sir - you are a rare commodity indeed. All I can say is thank the lucky stars we did not have to design the chemical , biological and electrical functioning of the body or we would never have existed. How in the name of everything did this all come to be?

[@pragooutube]

So much evidence of brilliant design! It's obvious there must be a Designer.

[@cameronbethea123]

@@pragooutube Maybe, but if so, who designed the designer ? A designer that can design life so complex must itself be vastly more complex than the life it designs, but if the designer itself wasn't intelligently designed, then something even more complex than us, came from nothing ? I believe its possible that there is a creator, and I like to imagine that there is one, but It's not possible to say with any degree of certainty that one is necessary to explain the universe. That belief requires you to assume that there must be a first cause of all things, and that this cause is a specific intelligent being that somehow exists outside the universe entirely, which, although possible, it can't be proven, and isn’t the only conceivable possibility. Maybe the universe is all that there is, and it is cyclical in nature, running in a loop for infinity, like a broken record, meaning it causes itself, or maybe there is an endless multiverse. It isn’t possible to prove or disprove any of these theories right now, so you can’t accurately say if they are more or less likely than a creator being the first cause.

[@pragooutube]

@@cameronbethea123 I've come to the realization that the amazing complexity of life, the precision, means that I have to humbly accept that the Designer's origins must be beyond my scope of comprehension- beyond my realm of understanding- miraculous if you will.

[@niranjanpaul2176]

@@pragooutube sure it's too perfect to be an accident

[@niranjanpaul2176]

@@pragooutube like how many actually expected the covid was going to happen to humanity

[@billc7211]

Another great teacher in the medical community! Thank you for allowing Dr Dayspring your platform to explain this.

[@esotericsolitaire]

Wow. Our bodies are so amazing. We should take a moment and meditate on this wondrous creation and thank it for all it does. I'm serious.

[@StocksDoc]

yes, thank God for creating such marvelous creatures

[@johnumiastowski9501]

Yes, but meditating on this fact would be of no benefit to me. I'd rather spend the time reading scholarly reports.

[@bobbyadkins6983]

Thank God for it. He created us.

[@JeffreyMartin]

Our bodies are an ad hoc bunch of spaghetti code with many questionable and obsolete mechanisms. Can you tell your god to stop giving kids leukemia? KThanksbye

[@0ptimal]

So we are kinda gambling by freely eating fat and cholesterol rich foods? If we don't know how our body is behaving with it? I knew there was variability in how food affects people, but it goes much deeper than I thought. Glad KZbin recommended this to me.

[@MKstudiovideo]

At first, I played the video with the notion that I already knew everything important about dietary cholesterol and its effect on our cholesterol (since I watched Gil's previous video on this topic). Yet, I learnt a ton of new information. I really hope more people like Tom Dayspring exist who are experts in their domain of interest and who can simply explain such a difficult topic to a lay person. And I really hope you Gil will be able to find another such excellent people who are willing to do those epic interviews with you because it's a huge service for the world. Thank you both!

[@Harleyyelrah]

Pô I 😊

[@6789uiop]

He's great. I've been a Dr Dayspring fan for over a decade. Glad he's with Dr Peter Attia now.

[@alipainting]

I googled good HDL levels for women and. Got this: According to the Cleveland Clinic, a high HDL cholesterol level is anything above 80 mg/dL. An HDL cholesterol level of 60 mg/dL or above is considered protective against heart disease. A level less than 50 mg/dL for women is considered a major risk factor for heart disease.

[@sd200man]

The complexity of our systems is beyond amazing. This has given me a new appreciation for how complex the cholesterol issue is.

[@kamerad4212]

Agreed! Everything about humans is being revealed as beautifully efficient and yet so complex.

[@DrBradStanfield]

This is an amazing discussion. Love that this high quality and evidenced based information is now available to the public

[@larryc1616]

Yes, the facts are here but your common layperson is easily manipulated and fooled by quacks like Ken berry. You and gil are straight shooters. A debate with Ken berry about the carnivore diet can help laypeople understand the truth about nutrition and health. How do you combat quacks from killing laypeople?

[@MrRobertFarr]

Yes. There's some interesting. Papers, available to read about eggs online. Did you see any good ones in free to access journals?

[@MrRobertFarr]

Hi, I am Robert Farr BSc Hons. A volunteer Scientist in England.

[@MrRobertFarr]

Mechanisms can be a bit misleading. It, allows folks to have a cheap, educated guess at what might be going on. I devised, a reaction mechanism once, by coupling together two accepted mechanisms. I asked, to see, my fellow students ideas, but, they would not show me, their ideas.

[@tombullish3198]

Monologue/seminar*

[@Radjehuty]

I sincerely hope anyone that watches this knows how much of a privilege it is to have this video as a resource. It's such an excellent overview and easy to understand for a concept that has a lot of nuance. It flies in the face of any diet that professes black & white verbage to describe whether dietary cholesterol is good or not. Maybe I'm in the minority, but I love hearing the "it depends" kind of answer. I much prefer precision over easy when it comes to answers about health.

[@ashleyfarias449]

ditto!

[@kenmken]

This video was incredibly informative, but I really don't know if "it depends" is the most honest conclusion, and I'm a bit dissapointed he did not discuss further specifics. It seems to me that hypercholestorolemia is a relatively common condition, and I can't find any information on the incidence rate of hypocholestorolemia, which is also linked to adverse health effects. If like I suspect the latter is much less common, perhaps it is misleading to say "it depends" like its some 50/50 split. With the way he talked about it, he portrayed hypo-aboserbers of cholesterol as having a blessing, so certainly not an adverse condition, unless ofcourse the body is also incapable of producing enough on its own. Seems like it varies how harmful dietary cholesterol can be to people, not that "it depends whether its good or bad". With that in mind and the fact that food is a package deal and the healthiest foods and diets are consistently rich in plants, it is a weird conclusion to make

[@adomasjasiukenas1425]

This was one of the best lectures I have ever listen about nutrition. This is what we really can call “nutriton made simple”. Great analogies. His passion reminded me of R. Taylor. I love people who are passionate about their thing and spread good, science based information in a understandable manner 🤩

[@Better_Call_Raul]

29:30 A man with an HDL of 60 is in the normal range. Why is that a possible sign of a hyper-absrber? Is it a sign only if the man's LDL is high? 🤔

[@Schatzie301]

What a brilliant explanation. I’ve been studying nutrition for over 50 years and this is the best and most comprehensive discussion I’ve ever seen.

[@erharddinges8855]

You are a dog?

[@AndyMorrisArt]

far too comprehensive for me. I'm just as uncertain now as before I watched it.

[@elduderino1329]

I've never heard a such a detailed, comprehensive explanation about this subject. It's so information dense that had to rewatch many parts of it to understand it. I feel privileged to be a subscriber to your channel.

[@jimcarbone2748]

Outstanding! If we only had more people like him to explain biology in such simple terms, we would all be better educated and equipped to manage our health in a targeted, meaningful and effective way. Kudos to you Gil for bringing his knowledge to the public.

[@nikkiguerlain]

Oh my gosh! Your guest is the best ever! He’s so animated and genuinely excited and knowledgeable.

[@peterobrien7465]

Dr Dayspring is a national treasure. His enthusiasm for this topic and they he talks is wonderful . Even a dummy like me understands it .

[@jimmccall8030]

This is SO HELPFUL. I am a hyper absorber with very high ApoB, high LDL, high HDL and have been eating 3 eggs daily. Going to switch to one whole egg and egg whites. Thank you. I’m reading and watching all of Dr Dayspring that I can find. Also I really appreciated your recent debunking of the saturated fats are fine report

[@markjonz]

Why continue eating one egg a day if you’re a hyper absorber?

[@6789uiop]

@@markjonz My question too. I started Ezetemibe and stopped eating eggs, etc.

[@MtnGirll]

@@markjonzeggs are addictive

[@davidsuzukiispolpot]

Regarding individual variability: I was exercising a lot and eating the recommended low fat diet and my body did not have excess fat, but I felt like I was not robust or strong and my cholesterol was going up. My doctor recommended statins. I asked what lifestyle I could do but when he said " eat less fat" I replied that was not possible since I already ate very little fat. He then said I was likely genetically predisposed to why cholesterol. Later, when I switched to a fairly high fat high cholesterol, low carb diet and I told him look. My cholesterol levels are very good and I eat a lot of cholesterol. He said maybe I have genetically predisposition to low cholesterol. I guess that doctor thinks I had successful gene therapy. In my case, I think my low fat diet contributed to a poor lipid profile and the general health recommendations and assumptions of doctors are not correct.

[@janiesherwood6403]

That is Soo funny, that dr doesn’t know his patient 😉

[@signs80]

It's likely because you were eating pretty poorly on the low fat diet. It isn't mentioned in this video, but studies show that eating refined sugar and refined carbs on a calorie per calorie basis is effectively nearly as bad as eating those calories as saturated fats.

[@k.h.6991]

For heart health it's the quality of the fats that matters. In other words: eat nuts and seeds.

[@alipainting]

This is EXACTLY my story, - what the doctor said word for word and what I did: zero fat, 100% carbs, which caused hypercholesterolemia. He said it must be familial. At that point I turn to Google and KZbin 🎉😅

[@ianlanford6922]

@@signs80 he said he is exercising a lot. 99% who exercising knows, that eating junkfood refined sugar and mcdonald is big NO NO. occasionally yes but not everyday or every so often. imo. the problem is that if you eat less fat. your body tried to make more. like video said. dietary cholesterol absorption for most ppl is half. but because he lack of it. the body then create more by creating from body fat and recycle it via bile/instentine. eating more fat then reverse this effect and body doest need any more cholestorol. hence cholesterol going back to normal

[@GreggBennett-j3p]

This guy is a rock star! Love the way he talks. Where is he from?

[@richclark6265]

A pleasure listening to an "enthusiastic master" of his subject. One able to explain complex subjects to the common man such as myself. Thanks for the great video!

[@c2964-o9e]

I worked with Dr Dayspring in the past at a laboratory. Brillant physician. Good to see him again.

[@pegatrisedmice]

I don't think you can do much in terms of how digestible your content can be when you're presenting actual facts, because facts tend to be more complex than eat this, do that and you'll be fine. There's also the problem of other influencers crafting their "facts" such that they appeal to most people and confirm what individuals already believe, and that generates more clicks (it's not fat it's sugar type crowd for example). So I'm very happy you took your time to interview someone of such great knowledge and explaining abilities, because I was confused about this topic for a while but this video cleared it up for me in a matter of minutes (to be fair i did zone out ofter the explanation of low and high absorbers because that kinda answered my question but i will definetly revisit this). Thanks

[@danyyboye]

Fantastic lecture! My mother has familial hyperlipidemia with total Cholestrol in the 300s to 400s, HDL in the 120 region. I (male) don't have such high levels myself but my total runs around 250 with HDL around 70, LDL around 150. So I guess I got partial genes from my mother, not full loss of function. I went on full vegan (no dairy or animal products) diet for 2 months and my Cholestrol only went down by 15points. It was very frustrating but now I see why. Thank you for this illuminating lecture. I think I'd be one of those who could benefit more from absorption blockers like Ezetimibe. Also perhaps invest my time more on diet changes that target better Cholestrol elimination (soluble fibers Flax seed etc..) Again thanks a whole bunch to both of you. I hope many providers will see this video and learn. No one suggested any genetic test for my mother. They just put her on statin and that's it. Seems like she could benefit more if Ezetimibe is added. (BTW gonna have to return the phytosterol supplement that's on the way. Y'all might just save me from some damage on that front. Thank you!)

[@YouTubeStat]

You should have 100x the subscribers you currently have. This is a true service you are providing. You are a saint! Thank you so much!

[@michellecoffee7062]

Love your content! This is one of several key videos that convinced me to change my diet and do something about my cholesterol levels. All of my family has high cholesterol. In December, my total cholesterol was 391, LDL was 282. My family has been convinced that cholesterol doesn't matter. I finally decided to do something and went on a plant based diet in mid January. Before I ate mostly vegetarian but loved cream and butter (LOTS of them). After going vegan, my total cholesterol is down to 207 and LDL is down to 118. I expected a little bit of a drop, but nothing this dramatic! Thank you for taking the time to make these informative videos!

[@NutritionMadeSimple]

that's incredible, great job!!!!!!

[@Crowmother13]

My cholesterol is high ish. And I have cardiovascular disease. Stage 1 and Stage 2 hypertension. 5 ft 6 in tall and only 108 lb. Not diabetic. Cardiologist told me since it is familial that diet won't fix it. Wants me on meds.

[@Docneel]

Wow. Dr Tom dayspring is amazing at teaching complex concepts in a fun and interesting manner. Such a delight listening to him. Im a doctor from India. We read all about cholesterol synthesis, absorption and receptors in med school but never had a professor who could engage the students so well. Id go back to med school again if i had such professors. Thank you Gil.

[@jacksarem9480]

Thank you for the information. This was the best explanation of the cholesterol management

[@maimai-bd2iw]

I am only a high school student, but I find your work very inspiring. ❤

[@peter1835]

I have been binge watching this subject for months due to having gallbladder attacks which i think is linked to having high cholesterol (had other symptoms which are slowly disappearing over the past 6 months due to a very low cholesterol diet). I wish I had seen this video months ago best explanation I have seen by miles!!!

[@bartcop2742]

You were right in the intro to this video - This really is one of the best all around explanations I have ever heard. Thanks for posting this.

[@the_real_espada]

Can't believe this is freely available on youtube. This is gold standard content, almost a book compressed and summarized into very understandable format. I'm subscribed!

[@cosmicviewer477]

I could listen to this doctor all day. He makes this so interesting. I bet at some point he was an educator/teaching doctor/trainer.

[@2annec97]

A very useful and informative video. It helps me understand my mum's condition better. Some have commented that the speaker is a little too "long winded" but I don't find it so. Thank you for making it easy for me to understand better! Really thanks a lot!

[@LDUB250]

Thank you so much for this video. One month ago I suffered what doctors initially thought to be seizures but turned out to be a TIA (mini stroke) at 42. After thinking I was living a relatively healthy lifestyle, these past few weeks I have been on a learning journey. Thank you and Dr. Dayspring for this informative video.

[@L.NyE.D.IleanaAcevedo]

Muchísimas gracias por este video y esta entrevista. Me encantó la forma de explicar del Dr. y ahora también soy su fan.

[@patrickvanmeter2922]

Thank you so much for this. I'm 81 and you have answered questions I have had since I became old enough to say the word Cholesterol. Getting a little schooling on this has helped me understand where to go from here. Thank you again. Subscribed and liked.

[@Dan-dg9pi]

Gil, the point about the bell curve within the population is extraordinarily important. We too often assume that the entire population is the same. Instead, what if every time we do a study there are 2 or three or five different subpopulations that react differently to an input. Suddenly, all those meta-analyses might be a lot less comparable if certain subpopulations are not represented or the input is slightly different. As you know, this is called Simpson's paradox and we ignore it at our peril.

[@N1976DL]

I had a lipid panel done the day after attending a kids birthday party, where I spent the day eating pizza, snacks, soda, cake, and ice cream. My lipid panel turned out pretty bad, and my triglycerides were in the 300s. That particular day was an exception, as I do not regularly eat like that.

[@theflyingdutchman787]

Wow, even I can understand this form of medical explanation. What a great teacher.

[@kathleenkulp240]

Had to listen twice, but what a wealth of information!! Gil, you are a blessing! Thank you for all your time and efforts.

[@mangepanges]

Such an amazing channel, and so refreshing with someone who is intelligent, educated but also refuses to take sides or sponsors. Would it be possible for you to break down seasonal allergies at some point? I have bad pollen allergies and some food allergies, would do basically anything to fix it but so hard to understand what treatments are actually real and what is just people trying to rip you off. Anyways all the best and keep up the good work.

[@omittapir5986]

I was totally engrossed listening to him! He have such an interesting ability to make the cholesterol, LDL and rest of the players in the story of high cholesterol come to life. I just imagined them as tiny walking talking cartoon characters and totally was into it. Wow! What a great interview. Thanks for inviting him to give such an amazing, eye opening interview.

[@aquamarine99911]

Fascinating. Dayspring REALLY knows his stuff. Yes, I'm a hyper-responder to cholesterol (determined via the lots of eggs for a month/no eggs for a month) test. And yes, my HDL tends to run high - usually 70-75. I used to be proud of it - hey, it's the GOOD cholesterol. But now I see that the situation is much more complex. Eliminating eggs, reducing EVOO (!?!) and increasing exercise (I assume) has helped me to naturally cut my ApoB in half, from 1.86 to 0.93 in the last six months. My target is 0.80. If Zestia helps me get there, I'm taking it. I'll ask my doctor to test those phytosterols. [edit] Now I'm down an ApoB of 83, but couldn't get it any lower even with supplemented psyllium husk. Oh well, at least I got my doctor off my back. Since my BP great, I'm not going to sweat it from now on.

[@hektor6766]

A channel name Nutrition Made Simple showed you how it is complex. Take your Zestia, as Nature intended.

[@aquamarine99911]

@@hektor6766 lol. Nature - i.e. the forces of natural selection - stops caring about us after the age of reproduction (which I am). So why should I care about Nature?

[@ccoodd26]

I'm similar to you with cholesterol and can't eat too much meat or else I feel it.

[@azdhan]

Many thanks for sharing Dr Carvalho. Dr Thomas Dayspring is a really brilliant lipodologist. Previous to see this, I saw his super informative and educational lipid series podcasts with Simon Hill on The Proof. I learned do many things that I was ignorant of, it clarfied many of my misconceptions and misinformation I had bought into

[@michaelglunk]

I’ve got high cholesterol and have been very diligent about what I eat. In many of your videos I hear you speak about the benefits of extra virgin olive oil for heart health. I hear the same about walnuts. I consume and love both! But what I don’t understand is how they are so healthy for your heart and lower LDL yet contain saturated fats. I get that they have mono an poly unsaturated fats, but the labels all say they also contain saturated fats and a fair amount per size. Something I monitor as I shoot to stay below 12 grams of saturated fat a day. So are all saturated fats created equal? Is there something different about the saturated fats in these above mentioned items? But how are these items so good for lowering LDL if they have a decent amount of saturated fat? Thanks for all you do and I hope you have some time for an answer!

[@rdmckeever7645]

Totally eggselent. Doctor Dayspring explained the complex pathways & the many variables in a way that made it easily understood. Looking forward to many more videos like this. Thank you for this channel...

[@gregmeissner9960]

This guy’s hilarious! I love how he personifies cholesterol molecules. Brilliant teacher.

[@michealfriedman7084]

No disrespect.. He reminds of Grandpa Munster of The Munsters. Lol

[@ravelanone9462]

Dr. Tom is hilarious! And all while explaining complex information to everyone. Excellent interview; thank you, Dr. Gil!

[@Thatsmessedupman]

Did you do one of these with him on triglycerides? I have always had high triglycerides lower than desired HDL and higher LDL . since this was about cholesterol and you mentioned it's a different subject, I would like to know the method, and why, anything we've tried so far hasn't done anything and if it really is the concern for heart health that the doctor makes out it to be, where can some people just have higher fats in the blood? I'd love to see something in depth about the fatty acids or a link to what you've done already.

[@marknasia5293]

Wow, what an excellent deep dive from the subject matter expert. Honestly, broken down in a way to understand the function and pathways. testing and options could really increase a patient’s ability to manage high cholesterol levels. I am grateful you had Dr. Tom D. on to explain this. ❤

[@KOZ-k1p]

The world’s authority on cholesterol gave us the best lecture !

[@texdentist]

I went on a keto diet with 16:8 intermittent fasting 4-1/2 months ago. I have lost 41 pounds, and got my new lipid panel yesterday to compare to a November 2022 panel. After eating lots of eggs, bacon sausage, beef, butter, and mixing in chicken and fish for the 4-1/2 months, my total cholesterol dropped a little - 149 to 137. My HDL is too low and dropped from 36 to 34. But Triglycerides dropped from 138 to 69 and VLDL dropped from 25 to 14. LDL was unchanged at 88. The good news was that my Triglyceride to HDL ratio dropped from 3.8 to 2.0. A very good change in an important indicator. I was very worried that my high fat, and fairly high saturated fat diet would send my blood lipids skyrocketing. But they generally stayed the same or dropped considerably. I see doctors who predict both ways -- high fat will increase cholesterol or high fat/low carb will reduce cholesterol. In my case, it was the latter.

[@eugeniebreida1583]

I am curious ofyour averagedailycarb intake during that 4.5 months-? Tia

[@texdentist]

@@eugeniebreida1583 I tried to keep it at 20 grams a day or less. I'm sure I went over on occasion, but not by much. I ate zero foods that were high carb during that time.

[@eugeniebreida1583]

Thanks so much for your response. I once went on a strict STRICT paleo carnivore (no carbs) for one month, and reduced ALL of my inflammation - to zero. I also reduced my carbs to zero. In the end this restriction caused me great problems in terms of hormones (cortisol raised) - too much energy/inability to find restful sleep. So I ditched it. I think I am going to try a strongly meat w/greens & very low carb vegges so that I do not go off the charts ketogenic (can still sleep) but finally knock off the know crap foods (grains, nightshades, bad seed oils a(which I dont consume anyway) but maybe the nuts which I do, in moderation. Not sure about my flax seeds/flax oil (omega3's, but not only). Any idease welcome. However I'm not a fan of pork for inflammation, nor highly processed meats (bacon in USA, etc). Thanks for your info!@@texdentist

[@DonaldBraman]

Just be aware that most low carb diets show results in year one that are reversed in year two. That won't be true for everyone because of individual variability, but it is true on average. I hope it works for you!

[@barbaramartinez7871]

This was by far the most comprehensive explanation of cholesterol and how it works. It was very helpful that it was pointed out we are all different in how we respond to it and it's not a one size fits all as far as our diets are concerned. Thank you.

[@mikeedwards1096]

This sort of explanation of how the body takes in fats/cholestol could do with a flow chart . Thanks though. Really great lecture

[@pamelaandpabloortiz6250]

I was a registered nurse for over forty years and while the experts presented are clearly knowledgeable in their fields I’m finding these videos to be hard to understand on first viewing . I have always found the way you deliver information to be very easy to comprehend . This is not to show any disrespect to your guests but emphasize the importance of your summaries at the end . I went totally plant based four months ago and total cholesterol only dropped 18 points which was very disappointing . Please continue with your very easy to comprehend presentations. Thank you .

[@Nicksonian]

I don’t think it was difficult to understand. I went back and listened to a few lines again for clarification. I have listened to a fair number of videos about cholesterol, but I have no medical training.

[@NutritionMadeSimple]

the interview format is relatively new for me so I´m trying to get the hang of it and trying to figure out the best way to present them as we move forward (short snippets? long form 1-2h convos? break them down into 2 or 3 parts?) , so your feedback is important!

[@Nicksonian]

@@NutritionMadeSimple Perhaps some viewers are intimidated by longer videos, or just think, “I don’t have time for this.” But this particular video is best watched all at once to absorb the overall concept and how it all links together. Some of us are hyper-absorbers of information while others are hypo-absorbers. Ha, ha, get it?

[@lanazak773]

@Pamela and Pablo Ortiz Thank you for your comment, I feel the same way. I want the information to be "Made Simple" and I also like to see some practical suggestions. I'm really loving this channel (I'm burnt out on Keto and IF), and so far the "what I eat in a day" video has been the most helpful (and most simple).

[@Pixel-junkies]

@@NutritionMadeSimple probably snippets with you declouding said snippets. I found it fine, but I have been reading about these things for like ever so it just filled in a few blanks for me.

[@Nicksonian]

If you tend to the hyper-absorption side, an additional 15 to 25 percent absorption from dietary cholesterol seems significant. If, say, a quarter of the population is on the hyper-absorption side, then how has “dietary cholesterol doesn’t matter” become a thing? Of course, I’m playing dumb there. There are too many people out there pushing animal products.

[@travisporco]

It is so good hearing people who really know what they're talking about!

[@kenmken]

Great and really informative video. One thing I'm dissapointed about is how food as a package deal was barely glossed upon, especially with the mention of gut-flora and what dietary choices are associated with healthier flora. I think the issue of whether it's worth trial and erroring with your cardiovascular health and spending a lot of time and money on sophisticated tests, when dietary cholesterol seems mostly unnecessary, was also not addressed

[@erharddinges8855]

Gut flora does not like ezetimib, I quickly stopped it.

[@ClayMationNation]

Dietary Cholesterol is unnecessary, like pretty much every other nutrient in every other food we consume.

[@Firebuck]

Excellent video. Dr Dayspring does a great job of presenting this information. So many nuances!

[@apriljohnson6191]

Thank you for this!! LOVE LOVE LOVE. This video puts a lot of pieces together from your previous videos on ApoA and ApoB. I think I can go back to your other videos on the subject and get a lot more out of them now. I had questions on triglycerides and fatty liver. Can you do a video on this? It’s an epidemic in the United States and for those who have it, not a lot of guidance. I would love to see Dr. Tom Dayspring, MD, speak on the subject if he was inclined. :) Thank you both for this extremely informative video.

[@andrewstuhr8626]

This guy is a joy to listen to!!!

[@Diane-f1g]

Thank you , this is by far, the most comprehensive analysis of cholesterol and its effect on our body, wonderful discussion and so informative ❤

[@quinterodpablo]

Thank you very much for this video, Dr. Gill and Dr. Tom. It's a pedagogical content I'll go back to for reviewing and keep learning. The duration of the video was fine. It's a complex topic that needs several complementary videos. As some users have already suggested, I think it would be a great idea to have a similar interview material that goes through the metabolism, testing and individual genetic variability related to other lipids (triglycerides, saturated fat, omegas, phytosterols, etc.). I'm particularly interested in triglycerides and saturated fat. Once again, thank you very much for your professional and pedagogical work. Good vibes to all the team. 👍

[@JimLove1]

I cannot believe it took me so long to get your videos suggested to me. Maybe they have improved the algorithm!

[@felicisimomalinao1981]

Much thanks Dr. Carbalho for featuring Dr. Dayspring.

[@faricus27]

Thank you both so very much. I spent years trying to understand why my LDL-C and ApoB are high even after cutting the SFA almost completely. This was an eye-opener! I was prescribed statins, but I managed to keep my LDL at 130-140 with the diet and exercise, and this is not easy. Now I have a Plan B!

[@douglasgoodman226]

This is Super useful information. I was on a mono therapy of statin, kept increasing all the way to 40mg. Added ezetimibe and apoB plummeted. Then kept halving the statin all the way down to 5mg with great results. Currently TC 81, apoB 34

[@sectionalsofa]

Wow, that's great! Statin lowered my ldl but not enough and I didn't want to increase dose so Ezitimibe was added. It did nothing at all. Now i'm on Repatha and that's pretty effective but I probably can use a very small amount of statin to get APo B to goal.

[@newyorkguy158]

There was a lot of new and valuable information for me here. What was missing was a discussion of the relationship between dietary fatty acids and cholesterol synthesis. That would provide a more complete picture. I wonder why he didn't discuss the role of fatty acids?

[@jasonvespa7452]

Jeez, this is gold. Thanks to yourself and Tom taking the time to do this. Dr Dayspring is quite engaging! Got many insights from this ... I may need to explore the possibility with my doctor that I have hyperabsorption of dietary cholesterol as my HDL is quite high. In the meantime, I have been reducing animal product consumption recently based on your other videos.

[@davidcooper177]

THIS IS THE BEST, COMPREHENSIVE, EASY TO UNDERSTAND EXPLANATION, ESPECIALLY THE VARIABILITY and divination AFFECT ON HUMANS.

[@Chameleon569]

Great content, thank you for all you are doing. I like your gentle and non-argumentative style of delivery. 🙏

[@cc2160g]

Very different interview from others but I really like it. It’s very informative and educational which is worth watching over and over again. I felt like I just attended a college class with a highly respected professor. Thanks for the interview. It’s so valuable and I’ve learned new knowledge.

[@martinbrown9980]

That was a very interesting discussion. Could you follow that up with a discussion on saturated fats effects on blood cholesterol.

[@danm8004]

He said early on in this video that there was none.

[@eugeniebreida1583]

Yes! Please a similarly informative vid re Sat Fat Consumption and chol/lipid levels that result.

[@zedgarden]

Simply amazing. Watched twice. Thank you

[@donsantiago1]

I don’t eat red meat but i ate 4 eggs a day. I take a lot fiber, flax and chia. I exercise consistently. I smoked 3 to 5 cigarettes a day, I quit meanwhile. I’m going to be tested next month, i feel reasonably well, considering I’m 65 and waiting for hip replacement surgery , i hope I’n not doing anything wrong. I take multivitamins, palmetto, fish oil, plus reinforce vitamin D3 and K2. I take no other medication not even pain killers as my liver is too sensitive. I’ll try to watch this video before going to the doctor to check the referenced markers. I like your YT channel a lot. Your ethical posture unclutter complex issues, not by over simplification but with well backed sound information.

[@markjonz]

My HDL is 62 (high) and my LDL is 92 (lowish?). I’m unsure whether that could indicate hyper absorption or not? Should I get an Apo-B test? I’m vegan and don’t eat foods containing cholesterol and eats lots of fibre from plants.

[@fignewton8690]

Was on a fairly strict vegan diet, HDL 34, LDL 64, cholesterol 121, triglycerides 116. Went to the hospital with chest pains with 50% blockage in mid and 90% blockage in distal right coronary artery! Clearly my lipid profile is not indicative of this kind of blockage. I take a low dose statin now….I am more inclined to believe the newer theories of HDL to triglyceride ratios being more predictive of CAD since mine are high. The Norman pick cells are absolutely essential in cholesterol transport both in the gut and in the lysosomes of the cells. People low in this protein are linked to Alzheimer’s and dementia…. So I think there needs to be more independent research on endothelial damage causing plaque build up rather than a just a high lipid profile. I am also suspicious of high glucose/insulin levels (metabolic syndrome) causing this damage since so many diabetics lose eyesight, limbs, kidney function and healing issues. Our bodies are really smart, I can’t see them making a critical heart mistake over something (cholesterol) that is produced in the body and so critical for physiologic function including nerve and cell membranes.

[@jzen1455]

There is a study that showed a U-shaped correlation between LDL levels and mortality. Participants of the study with the lowest levels of LDL and highest rate had higher rates of death. I think they factored out between those who took cholesterol lowering meds.

[@fignewton8690]

@@jzen1455 I am familiar with the study. Check out A reassessment and proposal for food based recommendations.

[@fignewton8690]

@@jzen1455 it has to do with saturated fats and health

[@dvdmon]

@@jzen1455 Gil talks about this effect and how it can indicate "reverse causality" based on the preponderance of evidence and lack of additional data around how LONG these people had had low cholesterol. IE, you can have very high cholesterol for decades, adding to a plaque burden, but then start eating better, but still die because of all that plaque that's built up and eventually causes a fatal heart attack.

[@dvdmon]

My main question would be how long did you have these low numbers compared with how long you had higher numbers (from a presumably different diet)? IE, you can't blame the last diet you were on, unless it's something you've been on for many years, with causing cardiac issues, which normally take DECADES to develop. The only way to determine this is to get an angiogram right before switching diets, so you know the "baseline" plaque burden. Now, I'm not suggesting that vegan diets by themselves can or should decrease plaque the way some vegan doctors suggest (like Esselstyn or Ornish), but there's some evidence that they can halt progression if done in a certain way - IE a vegan diet that also avoids refinec/processed foods, and saturated fats (from tropical oils primarily). That doesn't mean you are out of the woods if you adopt one of these after eating "normal" diet for decades and have built up loads of plaque. It may halt progression, but you also may be close enough to an event that even a two week vacation where you end up eating lots of vegan junk food could tip you over. Not suggesting that's what happened to you, I just think that it's impossible to implicate a diet as a cause (or a cure) if it is not done a) consistantly, and b) for a relatively extended period of time - say 3 or 4 or more years?

[@eyemazed]

Question - dr. Tom says 70-80% of the cholesterol found in your intestines is going to be endogenous. Would someone following a keto diet have a much higher percenage of exogenous cholesterol in intestines as opposed to someone following a low fat diet? In other words, I'm interested in whether the sheer volume of cholesterol ingested makes a big difference in how much cholesterol ends up being absorbed into the body (individual absorption variability is only one part of that equation, the other is volume). Thank you

[@Nicksonian]

After this lesson, I don’t understand how higher HDL has gotten the reputation as being good, if high HDL is a sign of hyper-absorption.

[@lenguyenngoc479]

What you asked scientists already thought of it. They pick individuals with genetically high HDL. They found no protection from cardiovascular diseases whatsoever

[@AppleMasterChris]

This is why physicians have moved away from HDL as a good indicator. We now use HDL/LDL ratio :)

[@stx7389]

@@AppleMasterChris even that is not good, LDL or APO-B is key

[@lenguyenngoc479]

@@AppleMasterChris No....like the guy above said, ApoB only.

[@Nicksonian]

@@StanDupp6371 Just because old people have high HDL levels doesn’t mean that the HDL level has anything to do with why they’ve lived so long. Prove the cause and effect. You can’t. Attempts to improve cardiovascular health by raising HDL has largely failed.

[@utpalchattopadhyay]

Just outstanding! Please continue doing this nobel work!

[@PileofKyle]

Thank you for getting this guest on to share this important information in such a clear simple explanation.

[@christinebowman90]

love Dr. Dayspring

[@Retired1967]

Now this is what the internet is for, what great content. Thank you.

[@TylerArbour]

Love this guy! Thanks Dr. Dayspring for your enthusiasm and sharing your knowledge. 😅

[@shiv7743]

Dr. Tom is an incredible speaker.

[@nackedgrils9302]

Hi Dr. Carvalho, As always, I'm very grateful for the information that you're sharing with us. After watching this video I realize that the main questions I have about cholesterol are: What are its main roles in the body and how does low or high levels of serum cholesterol affect those roles and why does cholesterol have such a bad rep? I've mostly heard from the keto camp, so my understanding of it is that you can eat as much as you want and that it won't cause any problem unless you suffer from inflammation. I've also heard that it's absolutely essential for the synthesis of sex hormones in the body, so it's mainly a good thing. Also, understanding how cholesterol is synthesized in the body (and from what) and what influences the levels at which it's being synthesized would really help understanding the whole picture. Cheers!

[@suechurchill4375]

Thank you so much for this. I really appreciate the tremendously high standard of these videos. As someone who has always taken good care of herself ( diet, no smoking, exercise, sleep etc) I was shocked to learn that I have significant coronary artery disease and a calcium level of 7,000. I have since had a heart attack and received 3 stents. My question… how do I convince my consultant that I need to have the test for level of phytosterols in my blood and potentially reduce my statin intake ( currently 80) and take Ezetimibe? Any advice welcome. Thank you.

[@joebeta1837]

My cholesterol levels have always been high. I was 19 and right after Army basic training, our cholesterol was checked and was told it is was too elevated. I used to eat 4 eggs every morning and was on a carnivore diet. I went to my doctor and my cholesterol levels were WAY HIGHER than before eating that way. Screw that. I don't care what this expert lipidologist says. Eating more cholesterol will raise your cholesterol levels. And if you say, "Dietary cholesterol doesn't cause heart disease as this doctor says." Do YOU want to take a chance? Do you want to listen to this lipidologist who doesn't know you? Does he know your body? Does he know you're obese, diabetic, have a family history of heart disease, that your mother or father died of a heart attack at a young age? All I'm saying is be careful. Be careful believing these "experts". You're the one who's going to end up with a heart attack, not them. Just exercise very frequently, eat less dietary cholesterol, stay away from processed foods, stop eating high salt foods...and hope for the best. Take your statin.

[@icesentry]

So did you just completely ignore the part where he said some people are hypo absorber and some are hyper absorber. Or the summary at the end where he said that some people will eat 10 eggs a day with no impact and others will have significant impact if they stop eating eggs and that both are right.

[@sandiegojoey1]

I would love to see an equally long, detailed mechanistic explanation of how dietary fat affects LDL cholesterol. I understand the process where bile acids bundle lipids and bring them to the enterocyte docking station where Nieman-Pick C1 Like 1 proteins pulls them into the enterocyte (to be honest I can't remember if it only pulls in the cholesterol or both cholesterol and fatty acids), and then bundle them into a chylomicron to be secreted into the lymphatic system which makes it's way to the plasma. Assuming I'm somewhat right about that process. The part I don't understand yet is why there's a difference between the various forms of dietary fat when it comes to raising LDL cholesterol. I'd love to here Dr. Dayspring describe this process and where the specific difference occur.

[@patrickcrombmusic]

great video for medical students to understand this important area better. thank you !

[@andrewemery7459]

I have been told on multiple outlets that the choline in eggs makes prostate cancer worse, and I just had my prostate removed for prostate cancer, and a small amount of cancer is still there. Could someone clarify if eggs are dangerous to eat? I will stop eating them until I get some clear answers however many years that takes to do. .

[@stephenyoud6125]

Thank you so much for that. It was totally awesome. So complete a description and presented in an easy to undersatnd way by a clear expert in the field. very passionate and with a excellent and entertaining manner Dr Dayspring was amazing

[@williammaurer9450]

This is the second time I've listened to this! It's an excellent education on cholesterol issues. TYTY

[@delwoodkelp8590]

Excellent expert video. I'm guessing the information goes well beyond what most primary care doctors consider before going directly to statins. I'll discuss this with a friend who has a HDL of 103 and never tried Zetia before going to a high dose of Crestor. However I am left with one troubling issue.... Dr Dayspring's wall clock seems to need a new battery, as it appears to have been stuck at 1:53 PM during the entire discussion. But that never detracts from his obvious enthusiasm for the cholesterol subject.

[@jaiberjohn]

That's a fake zoom/gtalk/etc background

[@mohanapte]

Excellent video. If you are concerned people may be put off by long videos, you could time stamp the summary findings and put that as a disclaimer right at the beginning. That way people can jump straight to the conclusion. I watched the entire video and loved it.

[@jeffreywp]

Time-stamping content and listing that in the description is a great idea!

[@jewelsbarbie]

He already has the time stamps listed in the description.

[@nomi6798]

I feel I need to listen to this video two o three more times with pen and paper. Super interesting. Thanks!

[@rumidude]

OMG, I finally found an understandable explanation of dietary cholesterol effects on serum cholesterol.

[@patrickcrombmusic]

Really cutting edge stuff ! The UK seems way behind on this. Ezetimibe is only reccomended if statins are specifically contraindicated and the guidelines mention nothing about hyper / hypoabsorbers. And In the UK it would be extremely difficult to measure phytosterol levels - this isnt mentioned in any of the guidelines , whether primary hypercholesterolaemia or FH and the only mention of this test is in the context of the extremely rare condition 'phyphytosterolaemia (sitosterolaemia)' . GPs in the UK who are aware of this stuff are in a difficult position ! Starting ezetimibe over a statin, if suspecting hyperabsorption based on the cruder measures like HDL would be going against guidelines.