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The Extrinsic Apoptosis (Fas / Fas Ligand) Pathway Part 2

  Рет қаралды 22,680

Elliot Nicholson

Elliot Nicholson

Күн бұрын

Пікірлер: 16
@lazzatsarsenova6991
@lazzatsarsenova6991 6 жыл бұрын
Thank you for so patient explanation. Very helpful.
@michaelaurminska7390
@michaelaurminska7390 9 жыл бұрын
Very useful, understandable video. Apoptosis is not hard for me now, thanks :)
@daliahesham1002
@daliahesham1002 6 жыл бұрын
Thank you, it is very helpful video, easy and informative .
@medstudentforlife229
@medstudentforlife229 6 жыл бұрын
Thank you. This was very informative.
@dr.doaataha2164
@dr.doaataha2164 7 жыл бұрын
just wonderful:)
@gitapandey5952
@gitapandey5952 3 жыл бұрын
Can you please do a video on extrinsic pathway of apoptosis on testicular cell?
@diaasalami6867
@diaasalami6867 10 жыл бұрын
Thanks for your great efforts
@daanishmalik896
@daanishmalik896 8 жыл бұрын
Thanks sir!! thank you very much
@mahirabashir8714
@mahirabashir8714 5 жыл бұрын
Thanks a lot
@brcarter1111
@brcarter1111 9 жыл бұрын
What enzyme cleaves procaspases 8 and 10 into their prodomains aand small and large subunits?
@julietsebastian2486
@julietsebastian2486 9 жыл бұрын
From what I understand, the very formation of DISC results in the separation of the small and large subunits from the prodomain
@brcarter1111
@brcarter1111 9 жыл бұрын
Yes I see that, but a biological force is cleaving the procaspase into its prodomain, large subunit, and small subunit. Was just wondering what causes this cleavage, like perhaps a change in its charges, or if an enzyme degrades it.
@julietsebastian2486
@julietsebastian2486 9 жыл бұрын
Brett Carter The fact that the active initiator caspases cleave procaspases at cleavage sites further down the line seems to suggest enzymatic activity. I tried to look it up, but found little success...
@brcarter1111
@brcarter1111 9 жыл бұрын
Thanks, im having the same problem.
@momokasim1
@momokasim1 9 жыл бұрын
Brett Carter From what I know, Cytotoxic T lymphocytes or natural killer cells attach onto the surface of the targeted cells and introduce a protease known as 'Granzyme B' this is internalised and cleaves caspases leading to their activation :)
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