Thank you for so patient explanation. Very helpful.
@michaelaurminska73909 жыл бұрын
Very useful, understandable video. Apoptosis is not hard for me now, thanks :)
@daliahesham10026 жыл бұрын
Thank you, it is very helpful video, easy and informative .
@medstudentforlife2296 жыл бұрын
Thank you. This was very informative.
@dr.doaataha21647 жыл бұрын
just wonderful:)
@gitapandey59523 жыл бұрын
Can you please do a video on extrinsic pathway of apoptosis on testicular cell?
@diaasalami686710 жыл бұрын
Thanks for your great efforts
@daanishmalik8968 жыл бұрын
Thanks sir!! thank you very much
@mahirabashir87145 жыл бұрын
Thanks a lot
@brcarter11119 жыл бұрын
What enzyme cleaves procaspases 8 and 10 into their prodomains aand small and large subunits?
@julietsebastian24869 жыл бұрын
From what I understand, the very formation of DISC results in the separation of the small and large subunits from the prodomain
@brcarter11119 жыл бұрын
Yes I see that, but a biological force is cleaving the procaspase into its prodomain, large subunit, and small subunit. Was just wondering what causes this cleavage, like perhaps a change in its charges, or if an enzyme degrades it.
@julietsebastian24869 жыл бұрын
Brett Carter The fact that the active initiator caspases cleave procaspases at cleavage sites further down the line seems to suggest enzymatic activity. I tried to look it up, but found little success...
@brcarter11119 жыл бұрын
Thanks, im having the same problem.
@momokasim19 жыл бұрын
Brett Carter From what I know, Cytotoxic T lymphocytes or natural killer cells attach onto the surface of the targeted cells and introduce a protease known as 'Granzyme B' this is internalised and cleaves caspases leading to their activation :)