The Neurobiology of ADHD

Dr. Anthony Rostain, Ph.D., gives a good overview on the neurobiology of ADHD.
(Source: Online class on ADHD, Cousera, Week 5,
www.upenn.edu/p...)

[@CatLadyKorea]

Somehow watching this unedited video and being able to laugh, though lightly and nonjudgementally, at his attempt to refocus makes me feel better and understood.

[@skm0331]

omg thats what made me focus and get through it!!

[@annsan1722]

Me too 🤗

[@beatazalewska1492]

I love that this wideo wasn't edited it makes it much easier for my ADHD self to refocus on the important parts that you had to redo.

[@cactusjackie9145]

I’ll probably just meet you guys there

[@LandonTristen]

@@cactusjackie9145LOL

[@TheFaro2011]

As a scientific biology addict ADHD person. This is s blessing

[@Poppymeaganolive]

Same!!

[@嵐影湖光-r9z]

I can relate.

[@gabriellab2436]

same

[@idickers]

As a neuroscientist who was recently diagnosed with ADHD, I really appreciate this clear description of a complex disease.

[@Jo-razz]

I haveing troubles understanding or following of ADHD. I truly want to learn, how am different. How my brain are different. I had many test in 2018 by a Psychologist/neurologist. I didn't know what was wrong with me, my Anxiety attacks were Daily. I never Mention to him ADHD nor did he. For 2 months I had test after test even a brain scan. At this point I was so hopeless I was just letting him do it I have no clue why. After the testing he let me know that I that I am officially diagnosed with diagnosed with severe ADHD. He explained what it was. Mostly everything I struggled with. It has gotten to the point, I was scared to go back to work. I felt I always had to work harder then every one else. There where other things, that I had no idea, was ADHD. He said with Ongoing therapy and medication, you can Manage it, & start having a life you wanted. It took another month to see what was right for medication. I continued my Therapy and took took my medication seriously, taking as told. He explained the medication is a tool to help along with Therapy the medication is not a cure all. He had told me about the discrimination against against ADHD and that I might, experience it to only tell people that I trust. I was in my early forties and I and I felt like I just begun life there is hope I felt my best at this time it was working and I and I couldn't wait to keep continuing my Therapy allows my medication. I felt normal one for the 1st time in my life. People actually thought I was on medication for anxiety for anxiety because I wasn't always nervous nervous or taken anxiety tax I was more calm. Then do to help Problems my psychologist decided to retire. He had told me it is very important that you continue your therapy and your medication. I had gotten very lucky when he take me on as patient. I had other doctors from the hospital telling me how great he is. At the time I had insurance the covers the colleges it took me 3 months to find him the smooth of the psychologist on the list that was supposed to accept it said yesaid yes we can but we choose not to. I had to go without psychologist for 4 months finally I've done another one. I like him and we started our journey. Unfortunately my husband had the insurance and he got laid off from his job and lost that insurance. I worked but I did not have insurance under my work. I cried I had to stop saying my psychologist. I could not afford it. He was over to launch for 200 per appointment and you went to see me twice a month. I tried desperately to find anything that was affordable mental health care & there is none. Extremely disappointing what do we do if we are seeing a psychologist been taking medication in one day we do not have the money for it do we go back being unhealthy?? Like I said to change my life I was able to work again. Now that it has been several months it's getting harder and harder hang on. My anxiety came back I can barely leave my home. I can't keep my attention when anything no matter how hard I want to learn. My husband and I are a hard times. He needs me to be well. The way people treat me is awful. They jump to The conclusion is I just want the medication. Because I'm trying to find a therapist and maybe my family doctor can prescribe the medication if she only looked at my doctor records I gave her permission for it but she has not looked.. To show that I went through the proper test and through . It wasn't someone just saying oh well I think you have it let me get your prescription I was officially diagnosed ADHD. I take this so seriously it's saved my life I wish doctors would take it seriously to. So far I've been talking to doctors who insinuate that there's no such thing as EDH day or I'm just gonna jump in trying to get drugs. Now and I am a deep depression But what do you do if for example someone had bipolar important for psychology with would they deny them of their medication? I finally got an appointment with my family doctor, & a List of therapist so I continue my therapy. I had to say to her please I'm giving you access to all my medical records please look into it and you will see that this is a serious problem and I have been officially diagnosed since 2018. She said she'll give me an appointment within a month she will look into it and we will discuss it then. I'm so scared I have no idea what the outcome is. Trying to get treatment for ADHD and not having the money for a psychologist is near impossible. This has to changed. Here I am a person who wants to help myself. Follow every doctor's instructions and look where I got me?? It gave me a little taste of hope poop on how life could be good and then they said since you do not have the money you will have to suffer even though there there is things you can do that can be helped. I feel why doesn't this psychology world Start using insurance?? I was told the insurance was husband had to pay top dollar, Insurance cover psychology. Even then psychologists didn't want to take on my insurance. It was a good insurance and they were definitely going to get paid but I guess didn't want to wait. Knowing there's so many people out there that need help. I would never tell anyone that I have ADHD except my husband and my mother and fear I would get laughed at. Because sometimes has done so. I can learn all I want but if I don't get any men eat mental health treatment what is it all for? Has anyone else come across this problem is there a program out there I am not aware of? Please let me If there is I just want to be well again I just want to have hope.

[@ewonnestrand7298]

😢😢😢😢❤❤❤❤

[@khuziwesithole6719]

Praying for youuu🥹❤️ I hope you find lovely people who will help you with everything you need

[@scotishdude]

Thanks so much for not editing out the part before 11 mins - it literally helps so much at snapping me back in so i can finish this!

[@00Kath]

I absolutely love this real time presentation. I was diagnosed with ADD as a 5yr female and always trying to learn more about how my brain functions. Having a prestigious Doctor even stumble during a presentation just shows how we are all human and no matter where each of us is in life that as long as we try to do our best that is enough. Each new moment is a Moment to Start Over. I will keep this in mind when I am public speaking that my anxiety is normal my fear is also a human emotion to feel and that as long as I keep moving forward that I will make it through the difficult times and get on the other side of my struggles. We are all Human and as Humans we can come together to help learn, care, love and support one another. Thank you for showing this. 😊

[@jenskuhnemann1241]

Thanks for the video. Best one I have seen so far regarding the scientific background of ADHD. Are the other lectures online somewhere as well? I would be very interested in watching those too. Thanks again and Hi from Germany.

[@hattie.e.d]

This dude seems like such a sweetheart- I love getting to experience the "human-ness" behind a very factual, scientific video. It also really helped my understanding going back over the neurotransmitter section. I love that this was left in.

[@numbynumb]

Dr Rostain should mention that the functions and mechanisms of neurotransmitters are hypothetical constructs, not systems that have been characterized by direct observations or experiments.

[@ewonnestrand7298]

Now they have even to dopamin haven't they.

[@numbynumb]

@@ewonnestrand7298 Not that I'm aware of - and I've looked into it.

[@gaellem637]

thank you so much ! Just diagnosed, while going back to uni to study psychology, 37 years old, finally understanding myself way better ! THANK YOU for this video !

[@soultrick7474]

thank you for making this free to all of us

[@basiabarbara3365]

I only found out this video today… Even though it’s 9 yrs old, it’s still very accurate and I love the way it is explained! Thank you

[@l337g0g0]

10:00 his ADHD kicks in overdrive... HEHE

[@TheFaro2011]

Yannow

[@cobalius]

cute and also cool that he gets it uhm finished

[@stephaniecs100]

Lol - the feeling we all know to well

[@Joesu94]

both him and his video editor lol

[@sarahprosecco]

At about 10:00 & 11:30 this guy gave me hope 🤣 for the exams I'm meant to be focusing on doing but watching this instead...

[@HOOFBEATTT01]

This is what doctors must do (if I missed something)when it comes to prescribing meds.

[@tt3904]

Omg I wish I could watch the rest of the videos... this is so good to help kickstart my research paper.

[@darkestafrica3]

Do you happen to have the other videos from this course? it's no longer available online anywhere I can find.

[@perrydezeeuw96]

So which part of the neurotransmission doesn't function normally for people with ADHD? I get what the medication does but I'm wondering what really causes the dysregulation.

[@sen4744]

mid way through this i checked my phone and watched a whole other video without realising i was watching this one but im sure man is speaking facts

[@elizabethhendriks9030]

this was wonderful, thank you

[@shaunaghbrennan5969]

I couldn't even watch it all. Watched about 2 minutes and my ADHD brain thought nopee this is too much information

[@currypablo]

😂😂😂😂😂😂

[@80sbaby_grownalady20]

Me too😞😞😞

[@loveauditor]

🤣🤣🤣🤣🤣 I'm enjoying the video by the way

[@nutritionmyway2749]

Who edited this video? Come on man don’t do him dirty like that. This dude definitely has ADD I feel this so much though. Great information

[@raulguevaraquispe6084]

Thank you Dr. Rostain

[@neurodiversidadetdah9599]

Thank you for sharing knowledge Professor.

[@benutzeraccount5127]

10:08 All you need to know

[@4myownChanel]

Definitly not according to my experience but I havent figured out the perfect dose jet. =) Focus on the diffrent brain areas and pathways of the transmitters and look for ur behaviours based on those too. Oh u mean he stumbles once... i got it now...

[@zakirzak1494]

Alpha 1 receptors are post synaptic Alpha 2 is pre synaptic and it assists in re uptake of NE

[@How2TikTok.]

I’m not even diagnosed because I can’t get the time off work to see the doctor. knowing how life changing these meds have been for others is giving me hope that someday I may experience some level of normality. I can’t imagine what it’s like to feel so comfortable on the meds that it makes you feel lost when you’re not on them, I love your videos , thank you :)

[@isabellabihy8631]

Very well explained. How is it diagnosed? PET-scans? Oh well, and will my health care insurance pay the diagnosis?

[@lissaajz]

Isabella Bihy unfortunately no. There are no lab exams that can say if you have ADHD. Take a look at some online tests at CHAAD or ADDitude and if you still feel like it’s for you look a doctor at your area, the real diagnosis are clinical and made by a psychiatrist, neuropsychologist or trained psychologist ;)

[@wendyhannan2454]

You need to be diagnosed by a psychiatrist who specialises in ADHD. Good luck 😉

[@ViktorNyberg]

Could you add the rest of the lectures?

[@jenskuhnemann1241]

I really would like to see those as well. Did you find them by any chance?

[@scottleith614]

When you got to the synaptic cleft slide, I was like "goddamn this guy is garbage". But then you noticed your mistake, and corrected twice. This was a very genuine moment that showed you were noticing what I was noticing, which was nice. Really really great video, thank you!

[@TheRebellefleur27]

someone makes a mistake and you call them garbage?

[@o-segredo-do-meu-poder]

Luvely...very well explained... great that it was no cut... thanks for that

[@popinmo]

when you try to watch the smart science video to become intelligent but you just get distracted

[@G2thesecondpower]

I reaaallly want to watch this video about the neurology of ADHD, but because I have ADHD I really wish you could have livened this up somehow--I found myself tuning out around the 5-minute mark. A bit monotone--if you'd added some random blaring sounds maybe I could have stayed awake for this--no offense! ADHD'ers are in dire need of a "Bill Nye" the ADHD Science Guy' type of person to disseminate this information to us, lol. Perhaps if I use this video as a sleep aid, the information will enter my subconscious....

[@user-cx6ek]

Just choose the 1.75x speed, it'll be better

[@80sbaby_grownalady20]

Lol!!

[@madeinkonada]

I find the channel How to Adhd quite good in that way. Very digestible.

[@kjirstinyoungberg6092]

LOL-I love this guy at about 11:30...he must have ADHD.

[@sl5311]

I had the same thought when he was pausing looking for words ha

[@Cannabinol]

Haha yup. Dont worry brutha, we get ya! Tbf that was a lot of info. I'm watching this to see if I can regulate my symptoms with CBD. I'm the human lab rat, because these scientists are taking too long!

[@jeffmoss118]

Now we know how it works. How do we fix it?

[@johnmclean9711]

Watch the video 🤤🤤

[@JoaoBarroqueiro]

Great adhd performance ❤ love the video

[@lissaajz]

This is a very good scientific material! I was just looking for a book like this to comprehend my Brain 🧠 cause I have ADHD and Major Depression! Thank you so much Doctor!! Two things: does anyone know if those vitamins found on Amazon told to be “brain food” of some kind of “neurotransmitter vitamim” work? Do they do anything?Are they good? Is there any probrem in taking them with my meds? Does anyone have a material like this video about the Brain, neurotransmitters and Depression?

[@jenskuhnemann1241]

Hi, I just found this video and would like to see more Videos on ADHD (especially in adults) . Did you find anything else worth watching?

[@lissaajz]

Jens Kühnemann Sure! I probably have something for you saved right here. Just tell me something more specific about your case or what you’re interested... (like, in my case, I’m 31 and only been diagnosed with adhd now. I had it since childhood but no one even talked about adhd were I live, and I’m the inattentive tipe. Latter on, with adolescence came depression, again, for years people thought it was just a fase. It became very serious. So the comorbidity of major depression overcame adhd for more than 10 years and right now I’m pretty much impaired) Ok just just my case, for illustration, 😂😂, and that’s the reason why I’ve been searching A LOT on KZbin and internet in general. So shoot me and I’ll see what I got! ;)

[@jenskuhnemann1241]

I am 41 and have been diagnosed a year ago. I read a lot of books since then but most infomaterial is quite basic. As I am a medical profesisonal with general knowledge of biochemistry, physiology and (neuro)anatomy I am interested to know a bit more detailed and also would like to see / read where the medical research stands at the moment. I had a really hard time at school but somehow managed to get throught school and university but find myself having more and more issues in my everyday life (changed workplace 16 times within the last 14 years, getting into arguments with patients, wasn't able to keep a releationship for long etc.) meds are working well but there is still a big impact on my life.

[@pleiotr0pictrait]

If about ~30 billion neurons are Glutamatergic, GABAergic, 5-HT, DA and NA; what about the other 70 billion? are they electric gap-junction-like? are them silent?

[@terrancecloverfield6791]

10:05 and 11:15 I don't know if he didn't rehearse his slides, or that's the inattention/hyperactivity kicking in.....sometimes it's a tick that just causes complete disconnection from what we're focused on. Other times, it's just not practicing enough times.

[@dokterkerti4078]

Thank you for the lecture prof 🙏😇

[@exosproudmamabear558]

Fucking ritalin works like wonders but makes me go into hypomania still made me live the best 1 month of my 15 years of depression

[@rewtnode]

Can’t find the rest of the lectures. This was in coursera but can’t find it.

[@4myownChanel]

thanks - Found it yet sir? Any link/source/trace I can start the search from? Ill post if sucsessful.

[@Typhoon6317]

By regulating the Nero biology ADHD can be over come. On point! 👍🏻

[@xstensl8823]

and you end up living with cats like i did, but am happy

[@Hananssm]

Where can i find the other videos from this course? it's no longer available online anywhere.

[@ragexlukii2517]

apreciate u so much ty

[@jafferp5182]

What about effects of adhd medication ...amphetamine psychosis?

[@alanberkeley7282]

He won't tell you that probably being paid off by pharma

[@dr.ohhimark174]

At 10x doses when compared to treatment doses. Botulinum toxin (botox) is used for cosmetic purposes at microscopic doses. 1 gram of inhaled botulinum toxin could theoretically kill million people. Dose applied is important.

[@MegaGrawp]

I mean it is a risk. This is why you should have a psychiatrist that you trust and unfortunately as someone with ADHD it would be worth your time to understand dosing and drug interactions as I've found no shortage of people on the internet who are on potentially dangerous combinations of drugs. But if your shrink has a clue and you don't fuck around your chances of speed psychosis are very slim.

[@adrianusharjanto8570]

This Morning I see this Video. Thank for this video.

[@enderxx904]

This was brilliant, thank you very much!

[@azitaa8097]

Thank you

[@jozseftoth2538]

Excellent video. Thank you.

[@DewaldLouwChannel]

Good video. Edit the video and cut out that unnecessary segment at 10:00.

[@aremedyproject9569]

Dewald Louw I say leave it in:) I think it's good to see doctors are humans too. My best doctors all have that human aspect of being relatable. They're easier to communicate back and forth with. That's just me though.

[@l337g0g0]

Why would you want to edit out an ADHD moment in a video about ADHD and how the brain works and affects us?

[@Dancestar1981]

Sugar free monster ultra drinks have taurisine and b vitamins precursor to helping dopamine plus caffeine so it helps focus

[@leusmaximusx]

Where is the vidoe continuation please ?

[@hoffmanhoffman3747]

Does anyone know where i can find the original video so i can use it as a reference for a school essay (APA reference). The link doesnt work!

[@dreamznaspiratons7064]

this is great. what vitamins and supplements help?

[@savy1917]

I had to replay this video 3 times cause I couldn't pay attention

[@zv8381]

Excellent lecture!!!

[@SirArthurTheGreat]

Me trying to take notes then getting down wiki rabbit-holes

[@donyellperry4176]

what the matter with carlton banks grades?

[@donyellperry4176]

metal pyshics education they clashed today?

[@donyellperry4176]

my eyes changes?

[@keaten52]

Very good lecture

[@gjament]

I appreciated you restarting a few times to explain the Neurotransmission!! I would NOT have understood this concept if you would have just spit it out fast!! 🙏🫶 You did GREAT!! 😊

[@donyellperry4176]

ok then pain tolerance is she says inflame hearts want where you went anyways?

[@donyellperry4176]

she got her education from the mother and dad memory test days?

[@Nicholasvelaz22]

I love this

[@ChaoticButterfly]

>_> Umm... I think that bit about dopamine and norepinephrine is mixed up... add the hydroxylase to dopamine and you get norepinephrine, not take it away from dopamine to get it...

[@MissSunshine1953]

How come you say that the doctor has it backward? Where is your information coming from that makes it the other way around?

[@shivsethi4301]

literally the image contradicts what he said

[@donyellperry4176]

dont pickled smells?

[@donyellperry4176]

ln living bel-aire areas?

[@donyellperry4176]

they weapons checks?

[@donyellperry4176]

strictly business at from 1987?

[@timothygreer1464]

When.

[@donyellperry4176]

alfafa to them both?

[@donyellperry4176]

charlene wood had enemies she was chinese?

[@donyellperry4176]

pepsi ok worried about the safety of disney stars sign in at disney studios jun 25 2024?

[@donyellperry4176]

herpes of internal brain?

[@donyellperry4176]

mercer court in 1984 to hungary the country?

[@donyellperry4176]

damn man liv and maddie?

[@Cannabinol]

Basically: We (ADHD people) have issues with regulating our Dopamine and Norepinephrine (brain stuffs). This causes the symptoms we know and love. So, how do we improve this regulation? How does the Endo Cannibinoid System interact with this modulation - please tell me you are looking into that!? THATS THE LINK I'D LIKE YOU BRAINIACS TO CHECK FOR ME PLEASE. THANK YOU KINDLY, MUCH LOVE ✌

[@alanberkeley7282]

He won't tell you that. He takes money from Big Pharma

[@jesse7055]

They have drugs for it

[@harsheh]

@@alanberkeley7282 I love this shit. They make money off of us

[@donyellperry4176]

hello?

[@donyellperry4176]

cast of full house?

[@donyellperry4176]

katy perry?

[@michaelnahum6782]

Very informative, although at times a bit like watch actors on a blooper trying to keep it together.

[@chacalXXX]

❤

[@donyellperry4176]

must be her ?

[@donyellperry4176]

musty-bisciut feet?

[@donyellperry4176]

she had infants minds said her husband family?

[@soozshooz]

According to the other commenters, get yer selves a cat. Stick it in yer lap , take a Vivarin while sipping on a sugar free Monster drink that contains Tyrosine & Vitamin B + tequila…. That’ll teach your basal ganglia 👍🏻🤣

[@michaelvandenheuvel317]

ADHD+ASD

[@DwayneCoates007]

He must have ADHD

[@donyellperry4176]

calon no stayed reniasnnce had money to hotel for the trouble may have cause $176.00

[@dualityfirm4551]

Locus Ceruleus... like locus of control!

[@donyellperry4176]

she was bother by her mother and father about conditoner in the nude?

[@donyellperry4176]

but you in hurt faces?

[@damon123jones]

Get to the point youre trying to make...adhd brains are highly detailed very quick and have a high level of intollerence...so we dont have attention spent on useless tasks

[@donyellperry4176]

housefires and attempt on other lives matter?

[@alanberkeley7282]

Name / Payee City State Company Year Category Amount ANTHONY L. ROSTAIN » PHILADELPHIA Pa. Eli Lilly 2009 Speaking $7,950 Anthony L. Rostain » Philadelphia Pa. Johnson & Johnson 2011 Consulting $825

[@stevestevens9203]

What a Coincidence!!

[@exosproudmamabear558]

Fucking ritalin works like wonders but makes me go into hypomania still made me live the best 1 month of my 15 years of depression