Bupropion: What You Need To Know

Bupropion is an antidepressant and a smoking cessation aid. The drug has been tested in many other conditions, including ADHD, obesity, and seasonal affective disorder.
It has multiple pharmacological mechanisms and it's still not entirely clear how bupropion works.
Some recreational use has been reported, though the substance usually isn't very pleasant and it can be dangerous.
Overview Page (Including References): thedrugclassroom.com/video/bu...
Reddit discussion: / bupropion
Bupropion = Amfebutamone; Wellbutrin; Zyban; Quomen; Zyntabac; Budeprion
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The Drug Classroom (TDC) is dedicated to providing the type of drug education everyone should have. Drugs are never going to leave our society and there has never been a society free from drugs.
Therefore, it only makes sense to provide real education free from propaganda.
TDC doesn't advocate drug use. Rather, we operate with the intention of reducing the harm some substances can bring.
Feel free to ask questions!

[@edum.6353]

Bupropion is a miracle for me. From a totally disgusting state of misery and addiction to a new guy who doesn't drink or smoke in 6 months. Gone are the days of sadness

[@alpinemind9977]

Wellbutrin (after trying a few other anti depressants) has literally been a life saver for me.

[@timstadlmueller58]

Same, I love this stuff.

[@BlakeBowden]

Same

[@zdenkkk]

@@angelannnavarro10 tnx I will try..im so tired...and dont have will to live..on the outside im ok..but inside I must care so.much energy to just go through the day, people, socializing is so hard, tired thing for me...im on paroxat...I can talk more free, but im not happy, im still sad....tel me what about hair loss, I heard this drug is nb 1 for hair loss and Alzheimer diseases. Please give some words..thank you..love and peace...

[@zdenkkk]

@@angelannnavarro10 you are so nice and warm to me...I will burn myself with healthy food, running, positive thinking, perfectionism...I think I have to put to much energy to just pretend to be normal...and my emphaty knoks me downs inside...so happy for you...yes I think paxil and paroxat are the same..I can feel some improvement In socializing but feeling real ok is just a thought...and yes I can imitate it...but just imitate it...thanks

[@zdenkkk]

Any hair loss?

[@corymodzeleski7191]

It's been a miracle drug for me. I battle Schizoaffective depression, and Wellbutrin keeps my depression at Bay and keeps me from hurting myself.

[@arthurarthur5205]

You’ve got Schizoaffective disorder, depressive type.

[@Malchus13]

Im schizoaffective depressive type and i find bupropion doesnt do much..

[@sleepyhead8681]

I'm so happy it worked for you! I take it and it's the only non sedative psyc med that work's for me. SSRI's work awful for myself.

[@sleepyhead8681]

@@Malchus13 There are lot's of other options with psyc meds. Benzodiazpines, SSRI's and dozen's of other med types. Just find A good Dr. It took me around 7 year's to find all the the right med's for me. Good luck. :)

[@simplenipple]

How were your prescribed this, I’m tired of apprizol and all these others meds I’ve tried.

[@lwazi_the_rose]

I love how in depth this is, from chemistry to history. I appreciate it!

[@CleoPhoenixRT]

My depression had me sleeping for 9 to 14 hours straight and getting up was a struggle. My first week into Welbutrin 100 mg SR and my energy levels have made a huge 180. Thanks for laying out the seizure risks too, I've been scared because I used to drink heavily before starting welbutrin. I see why the doctor started me so low now.

[@isaacmettle]

Sound like u almost have narcolepsy

[@brin942]

Thank you for being transparent because i was prescribed bupropion 2 month and is/was scared to take it but my depression seems to be getting worst especially my energy level mood swing and lack of interest in things. I think I was try it

[@Augie13]

My Dr just prescribed me with Bupropion XL 150. This video helped me understand the drug better. Thank you.

[@pianowizard2861]

@Julia so 8 months later how do you feel on Wellbutrin i have been on it 2 weeks and have anxiety but that could be the coffee i drink

[@LiquidSpartan117]

Update(

[@zombieowen]

@@pianowizard2861 One year later, how do you feel? I'm at a week and a half right now. Had some good days, but some day I couldn't get out of bed.

[@diplomatsson]

ayyy same lol

[@darrylbrady8841]

Adderall, Percocet, Xanax, Oxycodone are all pain meds and other drugs. The only place to get hold of it without prescription is at👇 darkfax.com They are good and their services are awesome💯✅

[@its1ofgodsfreckledbeauties587]

My will power allowed me to quit smoking the 2nd day of taking Bupropion! I still get the cravings but I immediately put my focus on something else. I'm on my 5th day smoke free! My daughter is extremely happy. God is good!

[@clintbeastwood2433]

Freckled Beauty Still smoke free?

[@darkarkz7712]

update?

[@TejasKhedkar-mm2xd]

Hi

[@brandonas19871]

I love the videos. some of the chemistry is over my head, but everything else is really helpful. keep up the good work

[@gravitonium9672]

Great work TDC! I listened to all your podcasts on Spotify.

[@featheredpunk8366]

I used to be on Wellbutrin. One time when I was on it, I smoked a small amount of weed before I took a shower. When I started to take the shower, I became convinced that the bathroom detached itself from the house and was hurling through space and I was freaked out that if I opened the door I would be sucked into space.

[@hypolaristic]

I've read somewhere that bupropion can induce psychosis when combined with cannabis...

[@TheDrugClassroom]

That may be your response. However, it's not the response most people have. Antidepressants don't help everyone and they may not even be the best first-line treatment in many cases. Yet they are a useful tool for a very large number of patients.

[@TheDrugClassroom]

Do you have any evidence that supports that view? It's an incredibly weak argument. Even very low-tier evidence can get published in the many journals that exist. A documentary in the absence of actual data isn't evidence.

[@hypolaristic]

There are so many similar stories out there... It either saves or takes someone's life. People can become a different person on alcohol too i.e. sober being the nicest person and become violent when drinking. Especially the first weeks on SSRI's are critical for risks like suicidal behavior.

[@TheDrugClassroom]

It doesn't either "save or take someone's life". The vast majority of people have either no response, a beneficial response, or minor negative short-term effects. The rate of death or severe adverse effects is very low, which I also mentioned on the TDC site.

[@infinityowl4203]

first time i ran while on this stuff was so damn relaxing afterwards. If you start to get that general uncomfortable feeling from the medication I highly recommend exercising.

[@bertinii]

Agreed!

[@brianthomason5022]

Interesting point I will keep this in mind for sure

[@jonesaffrou6014]

that's the way we were supposed to deal with adrenaline/noradrenaline

[@michaelespeland]

Thanks Seth, have been waiting for this one for a while

[@ursula.m8265]

For me it is working just fine. I quit smoking after 23 years of the nasty habit. Started to lose weight and the only problem is insomnia also helped me quit klonopin after 15 years of use without feeling all crazy. Took me one month.

[@pianowizard2861]

wow you quite doing k-pins after being on benzos for 15 years ,how was that withdrawal i was 2mg xanax for 3 years had the worst withdrawal ever i had a seizure was rushed to the hospital i could not sleep or get comfy for 3 months i had restless leg syndrome and i was only doing 1 xanax bar sometimes 2 a day and jesus it was rough i been clean off benzos since feb 7 2018 i don't think i would ever take them again on a regular to dangerous for me how was your experience

[@user-yg1zz7nm3i]

it's sad how we are all sad

[@mdiscrashed]

I love this channel , I find the chemistry behind these drugs so amazing and this channel nails everything about them you could probably ask. That being said i have bad anxiety and some depression issues as well as narcolepsy , i tried ssri's and made me worse like angry and starting fights on stupid stuff and i hate Xanax also of course makes even more tired but i came across an talked to my doc she put me on the XL at a starting dose of 150mg a day and man its only been a week and this drug is amazing puts me in the best mood , anxiety is just super low and i got some energy and confidence to just talk to anyone where id just avoid them before truly amazing especially if you cant take ssri's or others definitely try this and huge thank you to who owns this channel for all the info you provid again just amazing ,definitely a big supporter thank you.

[@mikeb8046]

Great information, thank you. I’ll be starting it in a week, wish me luck.

[@arthurarthur5205]

Good luck

[@nikm2089]

Lifelong adhd sufferer here at 34, been on and off stimulants most my life. Now I'm getting high bp and can't take stimulants, bupropion has been amazing and I was surprised in it's ability to help me focus. It's also easier to sleep and eat while on this med. Good drug.

[@workingonitsoon576]

how long did it take for you to reap any benefit?

[@nikm2089]

@@workingonitsoon576 about a week

[@valeriabustos4100]

I’m also diagnosed with adhd and also find Wellbutrin xl definitely effective for my adhd!

[@valeriabustos4100]

I also enjoy how it’s not a controlled substance which makes it easier to obtain and gives me more peace knowing in the long run it’s much easier to get

[@nikm2089]

@@ergenekonualkslayanliberal1077 it’s still going pretty well , still take it everyday.

[@thenewleaves8258]

I had a depression episode that lasted 13 months. Within 3 DAYS of starting 300mg of Wellbutrin, I felt the veil of depression start to lift. I was able to return to work within 3 months of starting Wellbutrin. I've tried tons of SSRI meds and this was such a relief.

[@BladedArrowTBGamer]

just got prescribed and having also tried SSRIs im hoping to get some relief glad it worked for you fgriend

[@timblock3483]

SSRI'S have way to many side effects.

[@THE_PAJO]

I hope youre still good 💙🍀

[@parkersre-creation]

@VG Vamika Gautam I'm good! Currently not taking Wellbutrin because I felt ready to go off it.

[@_shadow_1]

@Mia-xs4pc Bupropion has considerably less intrusive side effects from my experience than SSRI (the main reason why I stopped my SSRI other than the fact it did not work). The only really problematic side effects to look out for are excessive stimulation, insomnia, SI, and seizures. I personally have experienced none of these and the only thing I get is a headache when the meds wear off (similar to a caffeine withdrawal) and it in fact even improves my sleep.

[@jamesbrannigan5620]

Love this channel its a great resource

[@salsamaniac5123]

Great channel Thanks for the valuable info bro

[@TopFrisch]

your channel is very helpful. Thank you for doing those Videos. (sry for my bad english)

[@alitumen2629]

Ibu800Abuse *-* making these videos*. Your English is pretty good you'd be able to conversation if your English is on the same level as this sentence

[@XephreWolf]

Man, this drug fucked me up for months when I got prescribed it. Bouts of hypomania, neurosis and even mild hallucinations. I'm glad it exists for the people it does help tho!

[@saechak206]

how are you feeling now?

[@brianthomason5022]

It's working for me. But I'm only on day 2.

[@XephreWolf]

@@saechak206 Much better. I got prescribed the medication for misdiagnosed ADHD+depression. It was C-PTSD and Wellbutrin didn't do anything for it. Talk therapy is doing wonders tho!

[@williamdaskunk9666]

@@XephreWolf I'm pretty sure my girlfriend has C-PTSD (she is currently just diagnosed with severe PTSD and crippling depression as well as Anxiety) so I understand what you're going through to some extent (though I note I of course don't know your trauma). Personally Bupropion has helped with my own depression quite a bit, so I am amazed how negative your reaction was. I hope you're doing better and found a healthy way to cope and express yourself. Also I feel almost obligated to state that I am only 16 and my gf 18 because I feel it gives a lot more context for my situation.

[@Elvis_Gonzalez]

Are you sure you don’t have Bipolar II disorder? Antidepressant medication can trigger manic episodes in those who have Bipolar disorder. I’m getting my Masters in Counseling so I’ve gotta know this stuff lol

[@johnchambers2860]

Good work!

[@rachelwilliams8340]

I just was put on this medication for Seasonal affective disorder, ADHD and to help curve my cravings from food and the negative effects of my binge eating disorder from BPD. I am now on 150mg Rx. Only side effect I have is dry mouth. Most of my family members are also on this medication for depression, and Seasonal affective disorder.

[@tmsk2011]

That's funny you mention the smoking cessation, I knew it had those affects. I started taking Bupropion (300 mg) a little over a month ago and I needed to quit smoking because of surgery coming up and one day I just decided I wasn't going to smoke and it came so natural that it shocked me. I just hit 4 weeks not smoking today (11/8/17) and I feel so much better and I still can't believe that I quit cold turkey so easily. My mood is much higher and I'm no longer depressed. I haven't felt so free from my own mind for many years. Zoloft never did this for me. Although I am more emotional, I cry easier but then I usually laugh because what I'm crying over is literally nothing to cry over. XD Anyway thanks for the video!!

[@Nick_nm]

Same here, I used to smoke about a pack a day and after I started wellbutrin I felt no need for nicotine and quit cold turkey aswell. Great drug apart from possible hair loss.

[@raydn23]

Personally, Wellbutrin helped me after kicking a daily weed habit. I always had a bad attitude and felt down after the dreaded withdrawal stage (about a few weeks). After I kicked weed for a month I came to a conclusion that I was smoking week to mask something else. I got prescribed this from the Dr and I’ve been a lot calm and my attitude is slowly coming to being normal and nice, and not a jerk.

[@siryizzur]

Same here, word for word same thing I went through after getting prescribed it. Glad you’re feeling better

[@dr.strangelove5320]

Very insightful. Thanks!

[@cutestshorts101]

Weed withdrawal? I wake and bake every day, but when I'm out of it, it doesn't bother me at all, I can go for months and not even crave it that much. I mean I still want it, but I'm not gonna drive 150+km just to go get it. I don't get weed withdrawal

[@baileerayban2078]

3rd day I have no craving for cigs ...i love smoking and now it's completely gross I have to force myself to smoke. Meaning my cigs aren't being touched. So crazy amen

[@shaguftamalik649]

Great video 👍👍👍

[@fallenangel9535]

Good information I'm on it it helps give a little uplift with feeling more alive and interested more in things

[@saechak206]

its the opposite for me. idk why

[@brbmassage]

Wellbutrin XL is the best anti-depressant for me. I take it first thing in the morning and it lifts my mood and energy without any negative side effects. I can’t tell I’ve even taken it, other than the fact that my energy is higher. I did lose my appetite (and about 10 lbs in the first 4 months) when I first started taking it but that effect has gradually decreased and now my appetite has fully returned. I quit smoking almost immediately upon beginning Wellbutrin since it made it impossible for me to get a nicotine high, so smoking was just frustrating and gross. Just 25 mg of Zoloft had me hallucinating and blacking out within 3 days (probably a severe adverse reaction) so if anyone else is having issues with SSRI’s, I’d definitely suggest trying bupropion. Umm but don’t snort it? 🤦‍♀️ Thanks for this video. I was curious how the drug worked.

[@PawOfData]

Whaaat? It gives me one hell of an appetite... Like to the point where im full all day everyday. But by now I can avoid overeating even if I still feel very hungry.

[@zdenkkk]

Still on it..any hair loss?

[@breeflores8333]

Do you noticed a major hair loss?

[@victormccain5320]

Great video.

[@pluppenkuppen6958]

I just got this perscribed and this description sounds almost too good to be true, popping the first one tomorrow so we'll see :D

[@kylecorreia4919]

How'd it go?

[@MrPizza206]

@@kylecorreia4919 you didn't hear what happened to him? He commit after it made him grow a clitoris on his forehead

[@jeffperrault8340]

Wellbutrin has been the best antidepressant I have ever been on and I have been dealing with mental illness for over 30 yrs.I have been prescribed everything imaginable.

[@daraghbrowne9041]

I have taken this before for depression I was Impressed with its anti- Smoking effect

[@user-tk3ou5ru1n]

I have taken it before as someone with both depression and adhd Didn't do much for me but I'm happy to hear it's helping other people

[@nicholeocornes543]

My favorite antidepressant for people who can't get out of bed! Try it!

[@bobsmith6818]

Hope so man

[@RYO-dy8rk]

Bob Smith how was itV

[@RYO-dy8rk]

Bob Smith ?*

[@takamasanishizawa8832]

I’ll start it soon. I cannot get out of bed so cannot wait to feel the effect!

[@LeonEllisZ]

so far so good! Just started earlier this week and I woke up with so much energy yesterday, it was insane! Idk if it's the drug that has had a fast impact, or if it was just a random day of productivity (they're rare for me, but they do happen).

[@jonesy2111]

This is the best antidepressant I've been prescribed and I take it with a mood stabilizer (Lamictal) because I was also diagnosed Bipolar 2... I have had major depression and Lamictal helped that also. Whenever I've tried other antidepressants they have made me feel weird or 'manic' irritable etc.

[@Flips2Clips]

I've been on 300mg for 2 and a half years. I was on celexa only for a long time before I finally added Bupropion. When I was on only celexa I would often get strong waves of depression and hopelessness. I was emotionally unstable and felt drained all the time. I was definitely lacking something in my brain and when I started taking Bupropion it felt like it replenished whatever I was missing. It took away the overbearing waves of emotional pain that used to overcome me all the time. That being said, although I consider it a huge help, I still get depressed sometimes but I've been able to pull myself out way easier ever since taking Bupropion I've never experienced any side effects other than dry mouth. I sleep fine but then again I've always struggled with chronic fatigue. I don't know if Bupropion made a huge difference in that regard but maybe that's because I'm just a naturally low energy person.

[@danman1789]

Yeah, same here. I'm just always tired for no reason. Since starting this drug I'm more motivated and ready to get things done.

[@dylanpennington1378]

I started taking welbutrin because I have had pretty intense executive dysfunction (what I believe may be apart of undiagnosed ADHD given how commong it is in my family and also due to my behavior during childhood) Welbutrin definitely seemed to improved my life and makes me a lot more stable. And even if I was specifically diagnosed I would much prefer welbutrin over something like Adderall

[@ryangoslin6636]

I recommend you hit up this legit plug they're very reliable ship to any location they got dmt,lsd, salvia,spores,microdose and other psychedelic stuffs

[@ryangoslin6636]

trippy_psyche1

[@ryangoslin6636]

They're on Instagram .....

[@brianthomason5022]

I just started Wellbutrin yesterday. Changed from citalapram and I have to say I feel better almost immediately.

[@guntherbeckman1257]

Celexa gave me bad insomnia. Wellbutrin is a great drug.

[@chaii_latte]

I'm changing from citalopram. Its making me soo tired and the brain fog is real. High hopes for buprpion* fingers crossed

[@brianthomason5022]

@@chaii_latte it worked for me man

[@Lolaxas]

Wellbutrin is not like other anti-depressants, I've taken a ton of them so I have quite the experience. Wellbutrin is the only safe anti-depressant I've taken, it actually works and gives me no side-effects.

[@victorious521]

It made me super angry the first week I’ve been on it idk what that was all about

[@jaryarteaga4784]

Wallbutrin xl en español

[@AkaiShizuku]

That is unfortunate, MrVagingris. I was prescribed bupropion and decided not to take it after seeing the effects of SSRIs (which I realize bupropion is not) on family members. Decided instead to smoke a lot of cannabis. It works pretty well but side effects include stacks of pizza boxes

[@maryamshahzad7090]

Lola .actually my dr priscribe me too for ptsd.i am so confused should i take or not?can u help me to make a decsion

[@wm9550]

@Maryam PTSD cannot be cured by medication but antidepressants may decrease many of the symptoms, depending also on which symptoms you suffer from most. Bupropion might be better than SSRI in PTSD, because of less side effects and improving not so much serotonine but dopamin. But PTSD can only be cured with traumatherapy, I would highly recommend IRRT ( Imagery Rescripting & Reprocessing Therapy) it took away all my panic attacks, flashbacks, intrusions, fear of knifes, constant fear of my loved ones dying, breathing problems, tachycardia, the sense of beeing stuck on the day the trauma ocurred... I finally felt alive and human again and was able to go through the pain, anger, dispair and sadness, let go and move on :) I think it is important to find a therapist you feel comfortable with that uses a method of reprocessing, eg. IRRT or EMDR. Medication may help make the current situation more bearable. I hope you get better soon! :)

[@Dustin_Quick_Holy_Smokes]

I’m exhausted all the time and heard good things about increasing energy. I hope this helps, as nothing else has!

[@SanjacPr0ductions]

You might have sleep apnea

[@JonathanWillis-bq1td]

This pulls me out of a rut but the shakes and on edge feeling stink. I'm glad it works fast.

[@christiangabriel1482]

Love your work man! Is there a chance you'll do a video on hydromorphone anytime soon? there are only few reviews and informative pages I can find on it in the web, while there is not a single useful video on it on YT.

[@TheDrugClassroom]

Yes, it'll definitely be covered at some point.

[@dust4546]

It is heaven and hell. Led my family down a dark path just from getting it iv mixed with morphine and pushed through with saline while in the hospital. It was so good I was scared shitless and for good reason. Next 14 years were lockup, addiction, and bad decisions. Wonderful drug some people just don't need to know what it feels like; iv anyways. Much different orally.

[@lilturbo31]

I've been on Wellbutrin for about a month now. The first couple of weeks were marked with terrible insomnia. I could fall asleep, but I wouldn't stay asleep. Also good to note, I work night shift so I had to switch up the times I would take it. ALSO... I run on caffeine.. or at least I used to. A combination of Wellbutrin and coffee would give me major palpitations and tachycardia. Once I cut the caffeine down, those symptoms drastically decreased. The major positive that I can notice thus far is that it definitely increases my energy and ability to focus. I've gotten so much more stuff done and have increased my ability to focus on tasks much more effectively. Prior to this, my depression left it hard to get up off the couch to do anything other than the essentials (i.e. go to work, eat, do laundry when it was overflowing). Now I find myself looking for things to do. DO NOT TAKE THIS BEFORE GOING TO SLEEP. I typically take it about a half hour after I wake up. I work night shift so I take it at 5pm and then 6 hours later (I work 12 hour shifts). This seems to be the best for me. You'll have to mix it around and see what exactly works for you. Also, I've seen other videos where it says that your have decreased alcohol tolerance. YOU SHOULD NOT BE DRINKING WHILE TAKING WELLBUTRIN. It is contraindication completely and can cause an increase in seizure activity. It is honestly hard to tell if it's affected my depression. My anxiety is a bit worse on this but nothing that I feel I can't manage. What has really helped is therapy. TO NOTE: I began therapy 3 months before going on any antidepressant. So this has been supplemental to that. I feel that worked the best for me.

[@patrickrea3847]

tesresterone should help get tested and dopamine in wellburton should get you motivated that's what I might do as other antidepressants deffinitlt cause erectile dysfunction commonly known as hard on and it stops you from ejeculating serious if you have a girlfriend or wife steroids and wallbuton sounds good

[@octaneblue6]

It only increases seizure activity if you're withdrawing from alcohol.

[@TheFishiexxx]

How did you switch up your doses while working a night shift?? I also work a night shift and am starting on this medication soon.

[@Slothisticated0252]

I take bupropion for my depression and ADD. At first I took 150mg and the first week was horrible. I was maybe even more depressed than before but because my doctor told me that could happen and it would only last 1 week maximum I knew I wouldn't feel like that forever. After the first week I didn't notice much difference before I was taking bupropion. My doctor upped the dosis to 300mg and immediately after taking it the first time I felt like a whole different person. I can even sit still and focus on my work now and I feel better than I have in a long time. I also smoke weed to help me sleep and I had no bad experiences with it so far.

[@jacobkudrowich]

@Barribudda ́ lmao

[@anonymerbenutzer5574]

I find it to be great for quitting smoking. I also have bipolar disorder and ADHD but it doesn't really do too much for others. I also take Dexedrine, Lamictal and PRN Klonopin though.

[@zeus9527]

This has also been used to successfully detox and sustain cessation of amphetamine use and addiction. Thought you would have put that in your vid.

[@pyramidheadsllc4330]

Did you know its chemically similar to methamphetamine .

[@ev1ilfreak]

Really? I used to have and kinda still have a crippling amphetamine sulphate addiction. I tried asking my doc for Wellbutrin and he said it's for heroin junkies etc. Stupid fucking idiot. Prescribed me Effexor which i have no intention of taking and i tried all the polular range of SSRIs. Didn't help. Gonna get this from another psychiatrist or from a bootleg pharmacy.

[@sexualsalt6016]

I take Auvelity (45mg/105mg) dextromethorphan/bupropion. It’s a rapid-acting antidepressant. Has worked amazingly for me.

[@TaMarAaQ]

Thanks for this information! I'm on Wellbutrin now and I recognise some side effects of it. I'm not trying to stop smoking, but now I only smoke one or two times a day and I even trow them away when I smoked only half of it! I still like smoking tho ^^

[@bploaded]

Hi and congrats for your Channel, great level! Coludidos you do one about AGOMELATIN, Thanks.

[@SprocketWatchclock]

My life has been improved significantly by this drug. I was prescribed several years ago.

[@NowWhat480]

I broke out in serious hives from this and had to be on steroids for 6 weeks til it was out of my system. But it worked well for depression, just allergic to it.

[@joaquinrodrigogaraysherman5977]

I take Wellbutrin 150 mg but it gives me many side effects memory loss confusion and visual problems that is because of the Nicotinic blockade nach receptors

[@roboticfuzzball179]

This makes DXM so much better, almost like strong LSD visuals, dissociation head space, some times even holes.

[@ChicBeautyxo13]

I just started taking it and I don’t have any side effects. I can’t tell if it’s working. I’m hoping this is a good sign

[@TKO-qj5zx]

This drug saved my life

[@spearmint4093]

how?

[@carlosalbertogomezflores3732]

Can you talk about, Benzylpiperazine? Thank you, great videos.

[@documentofchange]

Just got a script for Wellbutrin SL. 100mgs twice daily (200mg). Thank you once again for letting me know what I'm getting myself into, Seth. 👍

[@documentofchange]

update I'm on my second week and I have horrible insomnia. Probably going to switch to the 150 XL instead of the 2X 100mg SR or just quit this all together. My brain feels like it's on fire from not sleeping well.

[@documentofchange]

update I am up to 300mg XL and it feels around the same as Adderall, so irritability and insomnia are my main complaints but altogether I enjoy being able to have sex and have the energy to get out of bed in the morning. The XL formulation taken around 7-8am is the best to avoid insomnia. At the end of the day is when the irritability really sets in. It has put a bit of a strain on relationships. I think it is due to the immense fatigue I feel coming down off the wellbutrin and having had a full day at work. Days I have either missed or skipped I notice that I am ever so slightly less anxious but also extremely tired. I am writing this at 5am because I am waiting for my sleep aid to kick in. If you have preexisting insomnia this medication can be a bitch, but again if you take it at the right time you should have to worry about the insomnia if you take the XL formulation. I did not like the complex dosing schedule of the SR formulation because it never seemed like I could get the timing right due to the fact the risk of seizure as with all antidepressants left me fearing if I messed up the schedule I might be in that territory. My writing has become extremely pedantic so I am going to guess that means the sleep aid is kicking in. Goodnight to whoever is reading this, and I hope you have a happy holiday season.

[@documentofchange]

@VG Vamika Gautam Pretty good actually. I got a daytime job now at a dispensary and my quality of life has been boosted tremendously. Getting good pay, everyone is nice, and the job itself is fulfilling. I've halted my therapy, but only for a few months now. I'm get more time with my gf too during the weekends too so our relationship has been a bit smoother going

[@TheMasterTelevision]

I use this, and its been a big help. It doesnt cure my depression, but it gives me relief from constant fatigue. Before I was taking 30mg of Adderall twice daily and not getting any help. Im now reducing my Adderall. I also realized, I had the will power to quit smoking cold turkey. I still had urges but it was so much easier to say "nah, I dont want to go get smokes".

[@trose22k]

My doctor just prescribed me Wellbutrin XL 150mg I haven't started taking it yet. I'm taking 20mg of Adderall 3 times a day. I'm hoping that when I start taking the Wellbutrin I can cut down on how much Adderall I take. Thanks so much for your comment! I feel less depressed already! Also how soon before you noticed any effects from the Wellbutrin? If I may ask..

[@trose22k]

Also congratulations on quitting smoking!! I quit smoking 5 years ago, the only thing that got me off smoking was using a vaporizer. Which I still use... when I started vaping it was before the juul or anything like that. I walk around with one of those big duchy box Mods. But it keeps me from going back to combustible cigarettes. Maybe Wellbutrin will help me quit vaping!

[@johnmike121]

It's more recreational than you think. IV is the more often used method by people who frequently use it

[@TheBowlofGravy]

Is it possible that you could make a video on Salvinorin B Ethoxymethyl Ether? I know it might be hard to make a full length video on such a new and relatively untested compound, however it is a very intriguing substance to myself and several other classmates, i have not personally done it, however it is gaining a fairly large fan base at my college

[@doughboi2145]

Fun fact the scare about siezures with this drug is pretty overblown. Siezures are no more likely on buproprion then on ssris. Another benefit of burprorion is it slightly increases quality of REM sleep due to its effects on acetylcholine. As opposed to ssris who significantly decrease sleep quality. It doesn't help everyone with adhd but as someone who has an adhd/bipolar comorbidity, it's one of my favorite drugs. It also helped me quit vaping! Avoiding caffiene with buproprion gets rid of the jitters for me. I know it's doenst help most people with adhd but as someone who can't take stimulants for fear of triggering a manic episode, I like this drug a lot.

[@cdh77]

This has worked for me except that it causes blurry vision.

[@jordyvanlinden8284]

I have the same problem

[@RichardsWorld]

I was prescribed this before. I read that it reduces the male refractory period. I believed this to be very true.

[@lannister6847]

You mean it did reduce it?

[@RichardsWorld]

@@lannister6847 I read somewhere that it does. I just started taking it again, but I stopped, because I can’t sleep more than 4 or 5 hours. I think it disrupts my sleep.

[@_shadow_1]

I had burnout depression related to unaddressed ADHD symptoms, this medication alone helped to address my mood, sleep, and even some of the disfunction issues. This medication is also useful if you can't tolerate stimulants at higher doses, you metabolize them too fast, or your provider is just really cautious about prescribing stimulants right out the gate.

[@stevensullivan5282]

This med worked for about two months 150 mg twice daily and then the vertigo set in... oh god the vertigo. Never experienced that in my life.

[@birgirkarl]

5:26 - best rapping ever!

[@DihelsonMendonca]

The effect of Bupropion is doubled sided: Sometimes at lower doses it improves depression, but depending of the other medicines you are taking, it may come to undesired effects. Several times I became very euphoric, then, agitated, then, angry and finally agressive ( Which I never was ). I noticed that it was due to bupropion, and I had to calm down using bromazepam to control. Even using the same doses every day, the results may be unpredictable, so, I avoid it. This drug even when used for depression can both bring heaven and hell to earth. Take care with bupropion and never mix with other stimulants.

[@ArtDelacreaux]

I had a similar story to that.

[@isolatedfromeducation5491]

Started taking them 3 days ago. The dry mouth for me is bad but it is keeping me hydrated which is nice

[@KUKAKYOTOTOKYO]

I was on Wellbutrin in highschool and I hated it. My psychiatrist wouldn't listen to my feedback and kept upping my dose over the years until he couldn't anymore. I kept asking to try a different drug, but he insisted. I was also taking trazodone with it, which kept increasing as well. After about a year I quit it all together without telling him. When he found out he was very upset. He had warned me before that it was dangerous to do so. A few years later I was diagnosed with sinus tachycardia. My symptoms started around the same time I quit taking my prescriptions. I wonder if my reckless decision back then had a negative affect on my heart. I see that one symptom is tachycardia.

[@christinab.2864]

Same here. The med cause sinus tachycardia. It has nothing to do by your bad choices it a side effect

[@janablang]

I took this when I was younger and how no side effects what so ever. I started taking it again, and had 2 grand mal seizures. This must mean I have a short seizure threshold which I read affects 1 in 1000 patients. So you just never know when a medication is going to turn on you.

[@Trrippy_Shades]

Just did 1000mg an I regret it bad worried

[@SRBOMBONICA86]

@@Trrippy_Shades wtf why so much ,what doctor prescribed you that amount ???

[@Trrippy_Shades]

Србомбоница it’s a stimulate, not prescribed more then 450, I don’t take it correctly obv, it’s very bad stopped doing it recently tho.

[@cutyoursoul4398]

@@SRBOMBONICA86 so much? she didn't said any dosage...

[@Inquisitorsofsatan]

This drug works good for both depression and ADHD. It doesn't leave me all strung out feeling like those feelings accompanied with Amphetamine and Ritalin.

[@OlafoWaffle]

I couldn't handle feeling boated, farting non-stop, and sweating at 60F.

[@jamesiron4010]

There is amphetamine in wellbutrin so...

[@clintbeastwood2433]

James Iron Please, link that fact that amphetamine is in Wellbutrin. I’ll be waiting....

[@soccrstar4]

James Iron Wellbutrin is an aminoketone, not an amphetamine. It’s far closer to a cathinone group that an amphetanine group.

[@TheUchihasparky]

@@djmemphisa did you know methamphetamine is prescribed to kids as a second line treatment for ADHD?

[@CharTheChair]

I keep hearing opposite opinions about taking Bupropion while smoking weed. Is it safe to do? I was prescribed Bupropion as an anti-depressant and stopped taking it after the first couple days due to increased anxiety but I want to try using it again to see if it works. I haven't gone to get a new prescription yet so I'm currently still prescribed it and have some and wanted to try it again today.

[@lukesonnenburg5006]

Seth, thanks!

[@lukesonnenburg5006]

Again

[@zakattack0075]

Bupropion is the Best ❤️

[@robertanthony7838]

this worked the first i used to treat depression woke me from a coma that i could no longer rewarded or pleasure

[@ronaldmacdre-gun9579]

thanks for making this vid

[@aalilyahwilson3909]

Hey so my psychiatrist prescribed me burproprin 150 mg twice a day with hydroxyzine 10 mg. After watching your video i’m definitely only taking one of the 150 mg a day. Thank you so much for the advice but I was wondering if you could possibly help me if you took the other meds with this as well ? My next question , what if you have all the symptoms like sleeping for 3 hrs and outburst, up and down moods ,upset stomach on the regular etc. but haven’t even took it yet ? Does it have the reverse effect?

[@N3wbMa5t3r]

I took Wellbutrin for ADHD and Anxiety- It made my libido skyrocket to the point where I was thinking about sex all day. Then extreme depression slowly started creeping in after about 3 months. My doctor then prescribed me Adderall which is like a limitless pill. I am currently taking Adderall IR 10MG x 3 daily.

[@N3wbMa5t3r]

@Jen 1990 I'm on Vyvanse 60mg and an Adderall 10mg IR "rescue dose" if I need extended coverage. (Vyvanse only lasts for about 6hrs for me) It is literally like a limitless pill...

[@mynameisearl8210]

I take 450 a day it's a underrated drug, it's great for depression, weight loss when you take meds that makes gain weight, and it helps out when you stop talking cocaine and meth, but some people go crazy on this drug, it's not for everybody

[@TheZoe555]

It's amazing! Nothing worked for me like bupropion!

[@lukesmith5373]

I just started it 5 days ago. So far I've had sore throat like drainage from allergies, mild aches and like I'm stuffed up. Anybody else? Does this usually go away after a while? Just wondering bc it would be annoying if I always felt like this

[@hi90163]

Hello, it was actually first intended to be an antipsychotic wasn’t shown to be effective and it was later discovered to help depression.

[@acidproductions11]

Great, but the ear ringing was miserable. So loud and disabled my ability to hear during the rings.

[@michellemichelle9143]

This is happening to me too and my nutritionist swears it’s not it 😂 😡

[@rainbowgirl765]

New to this drug in uk as antidepressant. 2 questions: Can you even have one glass of wine when on this or is it too high a risk for seizure? And how do people loose weight on this medication please?

[@luckyhappyman3195]

one glass of wine is never a dangerous combination with anything (in my experience at least). also this drug works on dopamine so it keeps you energetic most of the day, and at the same time it suppresses your appetite.

[@luckyhappyman3195]

@@sfrgth457 yeah it mostly work on norepinephrine, that's why you feel angry most of the time. the dopamine released in the case of Bupropion only works to keep you from going full out panic mood. but like i said "in my experience" a glass of wine never caused any trouble.

[@fluidthought42]

@@luckyhappyman3195 I wouldn't bother with wine when every other source pertaining to this drug strongly advises users to not consume alcohol since it can lead to a myriad of bad effects, including seizures.

[@SRBOMBONICA86]

@@luckyhappyman3195 no alcohol whatsoever with ANY antidepressant!!!!!

[@darrylbrady8841]

Adderall, Percocet, Xanax, Oxycodone are all pain meds and other drugs. The only place to get hold of it without prescription is at👇 darkfax.com They are good and their services are awesome💯✅

[@Amberischewyy]

I've been taking Bupropion for about 2 weeks now. The intial side effects we're annoying but not unbearable. After the first 5 days or so the side effects subsided. Just my experience. Anyways, I know it's advised to avoid alcohol while on this medication. Still I'm wondering if it would be okay to have just 1-2 drinks on occasion??

[@TheDrugClassroom]

It shouldn't be. I would definitely avoid frequent use and never go above a common dose of alcohol. But drinking once in a while isn't likely to be a problem. If you notice any sort of increase in negative effects, don't repeat using them together. And if you're on bupropion for depression, limiting alcohol is wise anyways.

[@RDLondon2023]

Felt completely depressed while on it!! Combined it with opiates though

[@420JackG]

My dad freaked out on this stuff.

[@Feelthefx]

Is it safe to mix with psychedelics such as lsd, psilocybin or 4acoDMT?

[@slazerlombardi]

I would also like to know this... For a friend

[@ahmedziada7146]

No

[@ahmedziada7146]

It could increase anxiety, blood pressure and liklihood of a bad trip.

[@johnmike121]

I've been on Adderall 30mg XR for a while and am about to start taking Wellbutrin 150mg and was wondering how they may interact. Also wondering if the Wellbutrin will interact with my Effexor or Mirtazepine. Thanks.

[@salsamaniac5123]

I can only speak from my experience I have taken Effexor ,Mirtazipine and wellbutrin .I didnt feel any negatives There is a warning when I checked for interactions it says Effexor XR oral + bupropion HCl oral Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed Effexor XR oral increases toxicity of bupropion HCl oral by unspecified interaction mechanism Additional Information: Keep bupropion dose as low as possible as seizures may occur.

[@user-cb3qr9dt2k]

Bupropion is used in the new medication Auvelity. A combination of 105 mg Bupropion XL and 45 mg DXM. The bupropion inhibits the metabolism of DXM, keeping it active for a longer time. This medication is a cheaper version of the Ketamine infusion therapy being used for depression and anxiety. and covered by insurance, where ketamine therapy is not.

[@4RC4NG3L.0]

I started 150 mg XL almost two weeks ago. Everything has been pretty fine other than one strange side effect. All Meat, coffee, and other "oily" foods smell and taste extremely rancid to me. I've come across other people on bupropion that have had this same side effect... I wonder what causes it?

[@terriarsenault5345]

How are you doing now? I'm guessing you're about 8 weeks in. I'm on 13 days. Wondering about any side effects. Have you raised dose yet? I heard that's common.

[@marisolarroyo5812]

@@terriarsenault5345 what are side effects I have been on 150 mg and I feel very nervous and stomach problems, nausea and bloated 🤕

[@oxxy6678]

Welbutrin is a stimulant, chemically its very similar to adderall. I used to abuse my adderall prescription pretty bad, and I remember after a night of getting high and not sleeping I would get up and try to force myself to eat something because my stomach would be upset from the lack of food. I get these microwavable chimichangas that I usually love, and eating it is like eating a piece of fuckin garbage. So basically the point is stimulants can cause some people to be repulsed by food. Welbutrin doesn't do this for me personally.

[@Mutantcy1992]

Why didn't they try the amphetamine version rather than the cathinone version? Body load is always worse with cathinones.

[@truthseeker1697]

can you do video on clonezepam and prozac please btw good video as always

[@NanoTryBox]

Wow, you're voice sounds so different in every video. Trippy. ^^

[@TheDrugClassroom]

It's partly from using slightly different setups for recording. I'm still working to figure out my preferred setup.

[@NanoTryBox]

Ah, alright. Sounds good anyways haha.

[@toddbedusek2780]

I haven't lost weight on it .. I was on paxil for a while ..

[@HeavyProfessor]

@The Drug Classroom - I became highly dependent on Wellbutrin while in rehab. I would cheek the pills and crush them and snort them. The effect is exactly like a mild cocaine high. Interestingly, it also has local anesthetic effects on the nasal mucous membranes when snorted, just like cocaine.

[@HeavyProfessor]

I was also on high doses of Gabapentin at that time, which perhaps contributed to suppressing undesirable autonomic side effects.

[@rogueking1463]

you know you can get high asf on gabapentin too right? shits awesome

[@Nike-fd2ow]

Yes snort like a cocain mild but anestetic mouth

[@SRBOMBONICA86]

@@Nike-fd2ow no omg don't snort it ,you people are fucking insane

[@darrylbrady8841]

Adderall, Percocet, Xanax, Oxycodone are all pain meds and other drugs. The only place to get hold of it without prescription is at👇 darkfax.com They are good and their services are awesome💯✅

[@charlotia]

Friend has been on for 16 year [generic 150mg ER] seems like the positive affects are wearing off. She was also precribed Zanax now as her best friend had passed away a couple of months ago, her dr gave her that just to take the edge off. Not sure if that is a good combo.

[@johnrojas9535]

Would like to see a video on trazodone

[@ryzeup5654]

Idk if it’s the bupropion but this was my second time taking it and it made me really drowsy almost a high ish feeling. i gave into the drowsyness and knocked out, before I knocked out I could’ve sworn I saw a comment where someone said they’ve been having crazy vivid dreams bc of it and I literally just had a crazy vivid dream that I remembered the most of, even the tiny details which has never happened for me, and it mixed some of my reality into the dream along w some tv show plot I’ve been watching LOL. So i wrote it down, but that was just crazy lmaoo

[@isolatedfromeducation5491]

Antidepressants usually cause crazy ass dreams. I had one too lol

[@LINCOLNMINAJ]

I used to get this type of incident when high on what is allegedly methcathinone (I don’t trust the info on some of these substances relative to what we get on the street) but since it is a stimulant that makes it impossible to sleep when you’re new/not immune to it I used binaural beats to force myself to sleep and I got these dreams everytime without fail, I could almost bet on it and I thought it was the binaural beats because i also did cat in my early teens and never had the crazy dreams occur back then. But something told me it may be the substance and not the tones I was listening to, despite it being an unfamiliar effect. After years of experimenting and attempted research, I am under the impression the black market narcotic market is also used as a method of testing new concoctions and chemicals before putting them on the legal/medicinal market 🤔