Saxenda vs. Wegovy - Battle of the GLP-1s for weight-loss!

Which is better?! Saxenda or Wegovy? Y'all wanted to know and it just so happens a trial published in January of 2022 answered this very question!
The authors of this paper directly compared Saxenda 3mg daily and Wegovy 2.4mg once weekly. One thing that is exciting about this paper is that it is a superiority trial - the goal was to see which drug was superior to the other. Who came out on top? Let’s take a look!
⚠️ Which did/do you think is better? Are you surprised by the trial's findings?
References
Rubino DM, Greenway FL, Khalid U, et al. Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults with Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial. JAMA - Journal of the American Medical Association. 2022;327(2):138-150. doi:10.1001/JAMA.2021.23619
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[@Sonora820]

I've been on Saxenda for about 6 months and I've lost 39 Lbs! I found that raising the dose every 3-4 weeks instead of every week has worked much better for me. Raising the does after only a week made me super nauseous and gave me bad stomach cramps. When stretching it out It's only mild symptoms after I raise the dose.

[@jasonjets7342]

What kind of stomach cramps were you experiencing? Like muscle cramps? In your abdominal area?

[@elenaflores6554]

When I stared my diet I was 310 I did everything and lost 50 lbs in 8 months.than I was on ozempic for 3 weeks and lost only 5 lbs now I've been on saxenda 1 week and I already lost 5 lbs I'm on the low dose still but it's working great I don't have any symptoms or issues and my insurance covers 100% I'm so happy im at 248 lbs currently... I was

[@behindthen0thing]

You was what

[@KyleHohn]

Was what lol

[@nicolet2218]

I am currently taking Saxenda i am on 2.4. have been on it since November and lost 15lbs I still have quite a bit more weight to loose but gonna keep on pushing 💪🏻

[@mqueen3755]

Do you mind me asking What insurance do you have?

[@kellycorona1185]

I wonder if more people discontinued Saxenda ended up switching due to it being a once a week shot vs. daily and not because of side effects at all.

[@m.macdog5113]

Hi from Australia . Not able to get ozempic because it's been held for diabetics only. OK diabetes is a serious condition so is obesity so can't get it. Just like to point out that diabetics as stated in literature by doctors can access literally 11 other drugs to manage their condition. Those who are obese can now only access one injectable which is double the cost . I don't want anyones health to suffer but I am really really salty on being priced gouged. It's not safe or fair.

[@Gromobran]

On saxenda almost two months- no side effects. Actually, I’ve notice if I overeat I’ll have throwing up feeling only that. Lost 11 kilograms. My doctor wants to put me on Ozempic after 3 months but there is a shortage of this medicine in the whole world so we’ll see next month- maybe I’ll be lucky to get Ozempic as I need to lose 10 more kilograms. The only downside of Saxenda here in Dubai is the price of the medicine. Crazy expensive

[@kellycorona1185]

Hello! Great video! I'm just starting my journey. I've been "keto" since 2014 and went off the rails last fall and gained 50lbs. My husband passed in December 2023 after a 3 year battle with cancer and I just didn't give a crap and carbed out. Doc prescribed Zepbound but Prior Auth wouldn't go through because of the shortage. She then prescribed Phentermine and said even if I take it once and find I can't tolerate it, that's enough for them to approve Saxenda. So that's the plan. I took Phentermine yesterday and was bouncing off the walls. I plan on calling Monday and asking for Saxenda. I'm a teacher and off for the summer so the once daily injection will be easier to do and I can do it when I wake up which is more like 9 or 10am in the summer. By the fall when school starts again, the shortage is predicted to be over so I'm hoping to switch to Zepbound or Wegovy then so I can do just the once a week dose on a weekend and not have to do it at 6am every morning before work. I'm glad you said that starting with Saxenda and then switching is what you do with a lot of patients so this sounds like a plan! I purposely waited until summer due to the expected side effects and of course now insurance won't approve it. Hopefully in the fall, supply won't be an issue. Thanks for all of your wonderful info!

[@sharonwillbanks7918]

I have been on ozempic now for 5 weeks. The first 4 weeks the nausea was bad but I took zofran to help. This is my 5th week and i did not have to take anything for nausea but I now have a huge burning type feeling/pain in my upper stomach. Will this go away? A little afraid to go up to .5

[@SG-hm6bb]

Excellent presentation! I've been on Saxenda for 8 months and have found that after slowly titrating up I'm just now reaching the 3 unit per dose injection! Yes, it took all of 8 months due to side effects and I was told just to titrate as often as I was comfortable. However, I've also found the initial weight loss has really slowed down and I'd like to see if I can get moving in the right direction again. I've been slowly gaining during the last 3 months. I feel that I'm eating too many carbs (I crave carbs and often 'think' that eating carbs will help with the slight nausea and uneasy tummy feeling). It seems to and I lean toward carbs for that reason...and most likely that's caused my weight gain? At any rate, I've listened to your encouraging words about eating more protein and will give that a try. I was wondering if should ask my doctor if I can switch to Wygovy or if after finally titrating up to the 3 unit dose should I stick with Saxenda for a while longer to see if I can turn things around? And yes, I'm one of those people who has been fighting with my weight for over 50 years, yo-yoing up/down 40-50 pounds several times in my life. I lost 60 pounds ten years ago and have been slowly gaining it back - at this point maintaining a 35 pound weight loss is a struggle. I'd like to maintain at least a 50 pound weight loss for the rest of my life. Thank you for sharing all this excellent information for a long-misunderstood and often overlooked chronic disease.

[@imamanc4life]

Carbs was not why you regained weight. Increase of calories did

[@MrMackingit]

As of Aug 2022 the veteran hospital and my local weight loss clinic have claimed a shortage of Wegovy. The VA are forced to push saxenda as Wegovy been put on hold according to doctors . Have you heard of this ?

[@marisastock2455]

Yes no pharmacy has wegovy I tried my doc prescribed but I got sedxea instead

[@Buy_My_Raptor]

I like what you said about switching between the two. Do you start at the 0.25 mg/week when changing to Wegovy after a patient is tolerating 3 mg/day of Saxenda? Starter doses of Wegovy are currently on backorder until further notice, so the switch you’re suggesting would be ideal at the moment. You have a great channel. I may be biased being a fellow PharmD.

[@theofficialdrdan]

If on 3mg daily of Saxenda I will start at 0.5mg of Ozempic/wegovy depending patient tolerance of Saxenda. Ie lots of sides with Saxenda titration I'll start at 0.25mg and go from there. I might only due 0.5mg x2 weeks before increasing. Again all depends how people do. The longer half life makes it tricky if they do have sides they are going to last for a while.

[@theofficialdrdan]

Thank you 😊. Always happy to help fellow pharmds!!

[@sarahburrier9123]

Yeah my doc had me go from 3mg saxenda to 1.7mg wegovy.... I have been miserable!! Going back to Saxenda because lower doses of wegovy are hard to get. I was doing well on saxenda so I'm hoping this will make me feel better and get my weight loss going in the right direction, for the right reasons! (Not from doing the poop'n'puke cycle!)

[@whitelight2624]

I was taking saxenda for 5 months with a total weight loss of 45 pounds in the first 3 months and hit a plateau for the last 2 months. I switched to weygovy 2.4 this week and feel like I had better appetite control on saxenda. Is this normal or does it take a little bit of time for weygovy to kick in ?

[@theofficialdrdan]

Yes takes time

[@whitelight2624]

@@theofficialdrdan weygovy side effects are brutal compared to saxenda! Sooo many GI issues

[@DebbieMcleod448]

@@whitelight2624 really?

[@whitelight2624]

@@DebbieMcleod448 yes really, the first week I almost gave up on wegovy. It got better as the weeks went on but I still think I had better appetite control with Saxenda

[@dhutmach]

My insurance does not pay for Wegovy, can you take Olympic 1 mg AND a lower dose of Saxenda? To get to something equivalent to the higher dose of the Wegovy. My insurance will pay for ozempic and Saxenda but not Wegovy

[@theofficialdrdan]

Unfortunately no. They are the same molecules and there would be all kinds of potential issues and unpredictable side effects.

[@PrettyPortUK]

I take escitalopram 10 mgs for depression. Have many people found their mental health gets worse on Saxenda. I haven't started it yet as was worried about depression. Thanks Dr Dan

[@aysebetulhoward9179]

Yes if you have depression saxenda triggers it too, actually saxenda is the worst for mental problems.

[@PrettyPortUK]

@@aysebetulhoward9179 Thank you for replying I still haven't taken and don't think I will. Not worth the risk thinking about a ketogenic diet.

[@temperancetaylor9244]

My patients complain of more cravings and show less weight loss with Saxenda over Wegovy/Ozempic. When Wegovy was on backorder, I substituted Saxenda and weight loss plateaued. The patient had to take more than the max recommended dose to lose weight at a much slower rate.

[@chandral2091]

Isn’t slower weight loss better for your organs?

[@ondrej1893]

Do we know where (%) Wegovy 2.4 weight loss actually finally plateaus if we talk from the very start of low dose? I assume 68 weeks still might not be the end of weight loss.

[@theofficialdrdan]

Yes it is slightly beyond that. There should be a new trial published any day now showing the results 2 years out. Prelim results look good.

[@behindthen0thing]

@@theofficialdrdan great to hear

[@AlphaGeekgirl]

So, if Wegovy is 2.4mg paw… and Saxenda is 3mg per day (= 21mg per week), Does that mean Wegovy, being just over 1/10 of the weekly dose of Saxenda, is less expensive? Somehow I doubt that the pharmaceutical company would be pushing a cheaper alternative.

[@theofficialdrdan]

No unfortunately that is not quite how it works. They aren't equivalent on a mg per mg basis. Wegovy is more potent mg per mg compared to Saxenda. The mg amount is not how the price is calculated on these meds in terms of comparison. However, cost of Wegovy at 2.4mg once weekly will be = cost of Saxenda at 3mg once daily.

[@NiniEJ]

I asked my doctor for Wegovy, but she told me that it’s such a shortage of the drug, most of her patients can’t find it. She prescribed me the new drug Zepbound, but it won’t be available for another few weeks. Therefore, I’m starting on Saxenda. I’ve loss 63 lbs all on my own but am having the hardest time getting under 200. I’m hoping this drug can help me with feelings of hunger and cravings. Thank you so much for the insight!

[@vilenationgaming]

Zepbound will be AMAZING! I have two months left of Wegovy and plan to swap to Zepbound

[@jkarimal]

Dr. Dan - just stared following you on KZbin. I am on Mounjaro 2.5mg and am trending to my goal weight. Knowing my insurance will most likely not cover it for weight management in the long term, what have you seen done using approved weight loss drugs for long term weight management? Thank you.

[@siljeknutsen1634]

Hmm.. When I tried saxenda (still going on it) i find the side effecs at the beginning to be the most helpfull.. When the side effekts vent away, then i lost the effect :( anybody that has the same experience?

[@megspositiveoutlook5772]

I could also see though that if someone on Saxenda is seeing that 6% average weight loss, for someone weighing ~200lb, that’s an average of about 12lb weight loss. I on a normal day will fluctuate about 5lb between food and water consuming, so 12lb total over months likely wouldn’t feel like much movement to me. Of course 12 down is a benefit, but it’s not enough to get someone to their weight goals if they’re obese. So if it were me, I might not be willing to tolerate the side effects if I’m not getting to my goals and not seeing much change. On a Wegovy type though, that same ~200lb person is losing an average of 30lb, considerably more loss, in a similar amount of time. It’s easier to tolerate when you’re seeing the visible changes. There’s no way to prove NN didn’t have any shenanigans, but I can empathize with the trial participants and feel like the dropout rates make sense.

[@downinahole193]

It's interesting that Wegovy causes more GI symptoms than Saxenda. I actually stopped taking Saxenda because it never stopped making me sick. I'm finding the opposite on Ozempic so far. Maybe a good potential warning for Wegovy and the higher doses. Another great video!

[@theofficialdrdan]

That is great to hear!

[@imjustheresoidontgetfined5269]

@@theofficialdrdan would you say either of these are bad for IBS?

[@janahal-juboori172]

Thank you so much. I was confused about what to choose and I am more clear now.

[@angeladlane]

I have had great success in saxenda, fir some reason I have recently put some of the weight back on !! I am in Canada and as far as I know wegovy is not available!! Hopefully this fall

[@theofficialdrdan]

Check out my other vids on why this might be the case.

[@dianeberthelot8754]

Hi dr. Dan, is wegovy available in Canada now? In Calgary?

[@carlad7246]

I'm wondering the same thing

[@EugeneHuman-kl1vc]

My chemist has a stock problem, apparently alot of places just go out of stock on ozempic. Now they told me i must goto my doctor and ask for another doctors script for saxenda or something else that is in stock. but now... daily inject is not the same as a weekly. and also now listening about the trials... and one showing less effectiveness... i don't think i want to get saxenda.

[@dianadickson8575]

I have been on Saxenda first but didn’t lose any weight so changed over to Ozempic. Been on it for 3 months but have not lost any weight. Why?

[@dianacazadora360]

Our bodies are survivors that’s why. They are very hard to crack. I’m going to have a gastric balloon instead. I’m fed up. I’ve tried everything 😤

[@sfiv1987]

Stop eating too much. Yes, it's that simple but very hard to do. Imagine yourself with no money, no roof. I guarantee you will eat less

[@PrincessPorkchopQT]

I just started taking Ozempic for diabetes and weight loss but I also follow a very low carb diet and I’m wondering if Ozempic is similar to metformin in the fact that side effects are magnified by carbohydrates. I have very little side effects, very minor nausea sometimes when I go too long without eating.

[@theofficialdrdan]

Neither drugs side effects should be magnified by carbohydrates. It is simiply GI side effects that resolve after the body gets used to the medication for most people.

[@penny_rb2687]

Can Americans sign up for the program? How would ordering medicines work as I understand British Columbia shut down distribution of Ozempic to the USA?

[@chenellewhite5231]

I'm in ireland and so far we are only in the "ozempic 1mg" camp, wegovy or ozempic in higher dose (I realise it's the same thing) aren't allowed here. But I've been on 1mg of ozempic for just over a month now and going good, waiting for wegovy aka a higher dose to be licenced but when it is I'm ready to run. My only question is that since starting I have chronic back ache on my lower left side. Without going into tmi I put it down to the drugs ability to cause constipation and perhaps it was related but as that side effect is lessening the pain isn't. Could it be related to the ozempic ???

[@theofficialdrdan]

That is tough to say. It could be constipation but it could be something else. I would follow up with your doc to confirm.

[@medebomb2000]

I lost 10 pounds in 1 month. On my second month now hoping to lose another 5 to 10 pounds. Was on 0.6 dose on 1.2 now. Barely can eat without feeling overly full.

[@missbeaussie]

This is very interesting. Due to the shortage I asked my Dr about temporarily switching to sandexa and she refused due to MORE GI issues.

[@Heartzs13]

Are you trying to say Saxenda? Not sure what Sandexa is....

[@theofficialdrdan]

Definitely not what we see in practice.

[@Gromobran]

I have not a single side effect on Saxenda. I havw notice if I over eat ( remember on Saxenda you literally can eat few bites) or eat like i use to before the medicine I would feel nausea, wanting to throw up. Thats it! People just want to eat more that they can and I think thats the reason for side effects

[@robinswebmail]

@@Gromobran I tried Saxenda and all it did was make me nauseous. Didn't lose even ONE POUND!! I'm going to try Mounjaro. Two of my close friends have both lost a LOT of weight on it. One lost about 40 lbs, and the other has lost about 60 lbs!

[@mariavirgen4680]

I want to know why does my injections stays in white area does not go to 0 am I not taking the full dose

[@isobel841]

Switched from sax to wegovy. Very few side effects, working really well and loosing faster. Plus able to actually eat!. Saxenda gave me horrendous stomach pains whereas wegovy doesn’t

[@joesaum]

I’ve tried Saxenda a few different times, each time I had to stop before reaching the max dose because my resting heart rate would go from the high 50s to the low 80s and I would experience the sensation of my heart racing. My doc now wants me to give Wegovy a try. I’m worried it’s going to cause the same issue, but I’ll be stuck riding any side effects for a week sense it’s a weekly injection and not daily. Have you treated anyone that has experienced this particular side effect? Is it possible that Wegovy may not cause this or do the medications typically have the same effects in individuals?

[@feli-vx2xi]

Hi did you ever try wegovy? And did it make your heart race. That's what I'm worried about cause I'm prone to heart racing for trying any weight loss medicine or too much caffeine or anxiety so I'm afraid these drugs will do the same

[@TinaBoo13]

@@feli-vx2xi I have SVT and started on Wegovy and I had a good experience with it. No racing of the heart. However, there is a shortage on my next dose, so I am trying Saxenda next week.

[@feli-vx2xi]

@@TinaBoo13 good to know. I just got some test results back so my Dr is gonna start me in either wegovy if it's available if not she said saxenda. I'm excited to try.

[@irektaflinski5449]

I just got Saxenda prescribed but now wonder if I should do wegovy ?? I’m confuse!

[@sfiv1987]

Stay off line and take what was given to you by your doctor. Some people just like to it more harder for themselves

[@semy4761]

I only need to lose around 10 kg so last year I used Saxenda for about two months (in February 2023) and had lost about 6kg. I than stopped due to the shortages. This year January 2024, I had put all that weight back on plus 3kgs more than my normal weight. So I started on Wegovy lowest dose, it is February now and Iam suppose to start the 1mg per week, I had spent £600 on Wegovy so far and I have only lost 1kg. I think what’s happening is that Saxenda helps you lose weight quicker hence much cheaper compared to Wegovy where you spend hundreds of pounds on titration lower doses before you even get to the therapeutic dose of 2.4mg. I think people drop out quicker on Saxenda because you lose weight quicker and than you stop due to finance. However you can’t drop out on Wegovy quickly because you don’t see the same quick results of Saxenda, hence once you start on Wegovy, you have to continue to higher doses to even see a result in the first place hence you’re tied in financially otherwise you end up quitting before the 2.4mg and wasting all the money you have already spent on Wegovy. 😢

[@theofficialdrdan]

You need to think about sustainability, not losing as quickly as possible. These medications are to be used long term.

[@tamarakramarov8590]

Hi Dr. Dan, I am 40, obese, pre-diabetic and have HBP and hypothyroidism. I take Ozempic to help manage the hunger and my binge eating disorder. If Ozempic stimulates insulin secritation in the presence of glucose - does it help to increase insulin sensitivity, or the other way around - encourages insulin resistance ( in brain, muscle or liver). I do need to lose weight but wouldn't Ozempic make my insulin resistance even worse ? Thank you

[@theofficialdrdan]

Nope. This is a rhetoric from the Low Carb zealots that is factually incorrect. While high insulin levels might have some very small role in insulin resistance there is a lot more complex underlying mechanisms that we haven't fully teased out that ultimately drive insulin resistance. Ie. genetics, liver fat etc.

[@kite6864]

what do you think of tirzepatide? will people on semaglutide still benefit from it? or you won't know yet till it's out?

[@theofficialdrdan]

People will be on one or the other. Trizepatide has a similar molecule to semaglutide!

[@kite6864]

@@theofficialdrdan will it be effective for people already on semaglutide? should we switch?

[@beeInCali]

Hi Dr. Dan I tried GLP from a local weight loss center near me. I have strange issues. I could tolerate the nausea but I couldn’t handle the crazy heavy periods (to which getting off caused 2 periods a month for months til I went on a progesterone cream to re regulate my hormones) and horrendous 3 day migraines. I suffer from migraines so I assume this didn’t help me at all when the side effects said it could cause light headaches. Nothing is a light headache for me. Anyway, I went off after three months. And I only lost 3lbs. The doctor at this center said he had never heard of any of my side effects except maybe from 2 of his receptionists who had heavier periods. Do you think that saxenda would be better to start on if I decide to go back on this? Wegovy is not available at my doctors yet. It’s on back order. Thanks Bee

[@markdeeming4765]

Hardly surprising that more dropped out of the saxenda group. Daily jabs vs weekly.

[@zahararay5611]

Yes! And I was thinking if they are getting amazing results on wegovy maybe they stay with it even if they feel sick, but with the saxenda the results don’t justify the discomfort so they drop out.

[@gemlight4670]

THANK YOU DOCTOR FOR THIS VERY INFORMATIVE VIDEO ! ANY OF THESE MEDICTIONS SAFE FOR 10 YEAR POST GASTRIC BYPASS PATIENTS WHO ARE STARING TO GAIN WEIGHT ?

[@trelipelakeable]

I had to stop Wegovy due to nausea/vomiting and diarrhea. Could not tolerate it. Hope to have better luck with Saxenda.

[@janturksoy3010]

Saxenda made my life hell I couldn’t even continue my everyday life even after suffering on it for 3 weeks I stopped

[@theofficialdrdan]

Unfortunately, some people can't tolerate these medications.

[@ondrej1893]

Wouldn’t they sabotage the % weight loss if they kept people on 1.7? Sure, adherence looks better on paper, but…

[@theofficialdrdan]

Possibly but they also know they are on the more powerful agent or 'newer' shiney one.

[@temperancetaylor9244]

What would you say is the equivalent dose of Wegovy to Saxenda? 1 mg?

[@ladymuskoka1015]

It sucks that because Wegovy is new its not coverd under my extended health plan. Stupid . They'd rather people be on all the other meds associated with being overweight than help people lose weight. 🙄 I'm on saxenda fully covered but Wegovy isn't. Ugh! Edit* I've been on saxenda over 2 years .. lost 25 lbs at the start ... nothing since . So just stopped saxenda.

[@JMSynthetics]

I believe they tried to put my wife on one of these and the copay after insurance was going be like 1200

[@chloenkitty]

Took one week of .24mg wegovy and was horribly nauseous. I stopped because the following week was a very crucial busy week for me at work and I could not afford to be so sick again. I’m ready to take the second dose after a week off and I’m terrified because I was unbelievably nauseous even when taking Zofran. It got to the point I had to put a patch behind my ear to function. Will this eventually pass because it’s hard to take or should I be trying a different medication?

[@theofficialdrdan]

It does pass but it usually takes a few weeks.

[@Heartzs13]

Is Ozempic and Wagovy EXACTLY the same as far as chemical makeup (not as in dose as Ozempic max dose is 1.0mg and Wagovy's max dose is 2.4mg) ? Is Ozempic and Wagovy the same? In otherwords can you push Ozempic to 2.4mg because it's the same as Wagovy...??

[@theofficialdrdan]

Yes exactly!

[@missbeaussie]

No. They have different active ingredients.

[@Heartzs13]

@@theofficialdrdan What do you think about Miss B below saying it's not exactly the same and they have different active ingredients? Can you clear this up for us?

[@Sarz85]

@@Heartzs13 They are exactly the same. Both are Semaglutide. Wegovy and Ozempic are just the brand names.

[@sfiv1987]

​@@missbeaussie👎

[@ondrej1893]

Btw Ozempic 2.0 approved in US, Canada, EU, Switzerland. Why 2.0?😀 I’m not protesting but it’s getting kind of confusing with Wegovy and Ozempic. My dad is already on Ozempic 1.0 so I hope it’s in stock soon and his diabetologist prescribes it. Also seems like a big jump 1.0➡️2.0.

[@theofficialdrdan]

Yes I just saw that. I don't think Canada has quite yet approved 2mg once weekly but will soon. I believe it is because they saw additional benefit in terms of blood sugar lowering. I will have to review the literature.

[@ondrej1893]

@@theofficialdrdan Yeah, still funny though. Current recommendations say it’s best to treat prediabetes/diabetes with fat loss and maintenance early after the diagnosis - so while I understand they monitor HbA1c etc., the goal seems to be almost the same for people with obesity and diabetes. The 15% weight loss often leads to diabetes remission.

[@theofficialdrdan]

@@ondrej1893 In general yes. It is interesting as the 2 go hand in hand with each other. We can't conclusively say where the fat caused the diabetes or vice versa. Essentially the treatment of both and 'metabolic syndrome' in general is the same process.

[@Britain99]

Which is more expensive? If taken for a year?

[@JohnAlexanderramboparyjrthe3rd]

They could of easily just given the patients on wegovy a placebo injection on the other days so they wouldn’t know which one they were really on but whatever.

[@hansherrera6969]

how long should i be on saxenda before going to wegovy

[@reneeperdue7635]

I have been trying to get Wegovy or Ssvenda but it is so high. Is there a way I can get it at a good price. I have tried everything.

[@apodaca309]

Seriously Mexico canada

[@tonyatiffanyofficial]

I was just in Columbia Mexico last week went to several pharmacies nothing I tried all week they said it’s a shortage

[@evamaynard3021]

I think more people are/were on saxenda so there's probably more complaints about it than wegovy

[@SW-hw9in]

Hi Dr. Dan. I’m a new subscriber. I really appreciate your videos and how knowledgeable you are. I’ve been feeling discouraged because I’ve been on Wegovy for five months now and it seems like I’ve hit a wall. I was doing well at first, losing 25 pounds. Then I started having weeks where I’d gain weight, then lose the next, then gain again. I can’t seem to get past that 25 pounds. I can’t find a rhyme or reason. It seems like the weeks I work out the most, I tend to stay the same or gain. I watched the video you just did about the drug stalling, and I’m going to incorporate more protein in my diet to see if that works. Thank you and if you have any other advice or words of wisdom, I’ll take it.

[@theofficialdrdan]

Eat more! Find your maintanence current weight in lbs x 12 and eat at that for a period of time.

[@SW-hw9in]

@@theofficialdrdan So, my weight x 12, and eat that many calories per day? If that’s what you’re saying, that blows my mind because I’ve always been told to eat less. The body is so interesting. Thanks for responding Dr. Dan!

[@theofficialdrdan]

@@SW-hw9in I always tell people. Is the 'eating less' or '1200 cals' working for you? If not what do you have left other than to try increasing your intake?

[@SW-hw9in]

@@theofficialdrdan Cool, I’ll reset. Thanks again!

[@medebomb2000]

I wonder if I might need to eat slower.

[@sfiv1987]

Lol...at the end of the day it's all about calories. Eat less

[@pinkpaws1870]

Do you have the doi/link for the study?

[@theofficialdrdan]

Here's the reference! I've also added it to the video description. Rubino DM, Greenway FL, Khalid U, et al. Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults with Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial. JAMA - Journal of the American Medical Association. 2022;327(2):138-150. doi:10.1001/JAMA.2021.23619

[@pinkpaws1870]

@@theofficialdrdan thanks! Once you mentioned the nameji was able to find it. Appreciate the link :)

[@leticiavarga1009]

How about Mounjaro?

[@theofficialdrdan]

See newest vid

[@jmpattison]

Cam you please not use just metric. I don't understand it. Im old.

[@theofficialdrdan]

I usually do metric and imperial.

[@sameday7144]

Hi, I’ve been on Saxenda now for 8 weeks, and I don’t seem to be loosing weight like everyone says I started at 85 kilos and I’ve only lost a kilo then the next week I gain that kilo back then loose it again, I’m on the full .3 mg but I don’t think it’s working for me , when do you think it will kick in and I start to loose some serious weight. Thankyou.

[@chris7921]

You weigh just 85kg? You don’t need to be taking this

[@sameday7144]

@@chris7921 I do when I have always been 65 kilos and in the last 3 and half years put 20 kilos on from giving up smoking all my adult life, and tried every diet and exercise in the book to take it back off, it’s not muscle or fat proportioned nicely on and around my body it’s just pure fat! Anyone who is overweight will try everything and 20 kilos is a lot to try and loose.